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Items: 1 to 50 of 78

1.

Publisher's Note: Chromosomal breaks during mitotic catastrophe trigger γH2AX-ATM-p53-mediated apoptosis. J. Cell Sci. doi: 10.1242/jcs.081612.

Imreh G, Norberg HV, Imreh S, Zhivotovsky B.

J Cell Sci. 2017 Oct 1;130(19):3418. doi: 10.1242/jcs.210682. Epub 2017 Sep 21. No abstract available.

2.

Chromosomal breaks during mitotic catastrophe trigger γH2AX-ATM-p53-mediated apoptosis.

Imreh G, Norberg HV, Imreh S, Zhivotovsky B.

J Cell Sci. 2016 May 1;129(9):1950. doi: 10.1242/jcs.190132. No abstract available.

3.

Clinical Severity of PGK1 Deficiency Due To a Novel p.E120K Substitution Is Exacerbated by Co-inheritance of a Subclinical Translocation t(3;14)(q26.33;q12), Disrupting NUBPL Gene.

David D, Almeida LS, Maggi M, Araújo C, Imreh S, Valentini G, Fekete G, Haltrich I.

JIMD Rep. 2015;23:55-65. doi: 10.1007/8904_2015_427. Epub 2015 Mar 27.

4.

Chromosomal breaks during mitotic catastrophe trigger γH2AX-ATM-p53-mediated apoptosis.

Imreh G, Norberg HV, Imreh S, Zhivotovsky B.

J Cell Sci. 2011 Sep 1;124(Pt 17):2951-63. doi: 10.1242/jcs.081612. Erratum in: J Cell Sci. 2016 May 1;129(9):1950.

5.

Segmental duplications and evolutionary plasticity at tumor chromosome break-prone regions.

Darai-Ramqvist E, Sandlund A, Müller S, Klein G, Imreh S, Kost-Alimova M.

Genome Res. 2008 Mar;18(3):370-9. doi: 10.1101/gr.7010208. Epub 2008 Jan 29.

6.

Profiling of copy number variations (CNVs) in healthy individuals from three ethnic groups using a human genome 32 K BAC-clone-based array.

Díaz de Ståhl T, Sandgren J, Piotrowski A, Nord H, Andersson R, Menzel U, Bogdan A, Thuresson AC, Poplawski A, von Tell D, Hansson CM, Elshafie AI, Elghazali G, Imreh S, Nordenskjöld M, Upadhyaya M, Komorowski J, Bruder CE, Dumanski JP.

Hum Mutat. 2008 Mar;29(3):398-408.

PMID:
18058796
7.

Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis.

Gal A, Sjöblom T, Fedorova L, Imreh S, Beug H, Moustakas A.

Oncogene. 2008 Feb 21;27(9):1218-30. Epub 2007 Aug 27.

PMID:
17724470
8.
9.

Why do we not all die of cancer at an early age?

Klein G, Imreh S, Zabarovsky ER.

Adv Cancer Res. 2007;98:1-16. Review.

PMID:
17433906
10.

Severe defect in thymic development in an insertional mutant mouse model.

Assarsson E, Chambers BJ, Högstrand K, Berntman E, Lundmark C, Fedorova L, Imreh S, Grandien A, Cardell S, Rozell B, Ljunggren HG.

J Immunol. 2007 Apr 15;178(8):5018-27.

11.

Mandatory chromosomal segment balance in aneuploid tumor cells.

Kost-Alimova M, Darai-Ramqvist E, Yau WL, Sandlund A, Fedorova L, Yang Y, Kholodnyuk I, Cheng Y, Li Lung M, Stanbridge E, Klein G, Imreh S.

BMC Cancer. 2007 Jan 26;7:21.

12.

Array-CGH and multipoint FISH to decode complex chromosomal rearrangements.

Darai-Ramqvist E, Diaz de Ståhl T, Sandlund A, Mantripragada K, Klein G, Dumanski J, Imreh S, Kost-Alimova M.

BMC Genomics. 2006 Dec 29;7:330.

13.

Multipoint interphase FISH in childhood T-acute lymphoblastic leukemia detects subpopulations that carry different chromosome 3 aberrations.

Haltrich I, Kost-Alimova M, Kovács G, Dobos M, Klein G, Fekete G, Imreh S.

Cancer Genet Cytogenet. 2007 Jan 1;172(1):54-60.

PMID:
17175380
14.

Modeling non-random deletions in cancer.

Kost-Alimova M, Imreh S.

Semin Cancer Biol. 2007 Feb;17(1):19-30. Epub 2006 Nov 17. Review.

PMID:
17174104
15.

Non-random genomic instability in cancer: a fact, not an illusion.

Mai S, Imreh S.

Semin Cancer Biol. 2007 Feb;17(1):1-4. Epub 2006 Nov 12. No abstract available.

PMID:
17158061
16.

Down regulation of 3p genes, LTF, SLC38A3 and DRR1, upon growth of human chromosome 3-mouse fibrosarcoma hybrids in severe combined immunodeficiency mice.

Kholodnyuk ID, Kozireva S, Kost-Alimova M, Kashuba V, Klein G, Imreh S.

Int J Cancer. 2006 Jul 1;119(1):99-107.

17.

Multipoint interphase FISH analysis of chromosome 3 abnormalities in 28 childhood AML patients.

Haltrich I, Kost-Alimova M, Kovács G, Klein G, Fekete G, Imreh S.

Eur J Haematol. 2006 Feb;76(2):124-33.

PMID:
16405433
18.

Jumping translocation of 17q11 approximately qter and 3q25 approximately q28 duplication in a variant Philadelphia t(9;14;22)(q34;q32;q11) in a childhood chronic myelogenous leukemia.

Haltrich I, Kost-Alimova M, Kovács G, Kriván G, Tamáska J, Klein G, Fekete G, Imreh S.

Cancer Genet Cytogenet. 2006 Jan 1;164(1):74-80.

PMID:
16364767
19.

[Identification of 3q21q26 syndrome by "multipoint" interphase FISH analyses in childhood myeloid leukemia].

Haltrich I, Kost-Alimova M, Kovács G, Kriván G, Dobos M, Imreh S, Fekete G.

Magy Onkol. 2005;49(2):141-7. Epub 2005 Oct 24. Hungarian.

20.

CGH analysis of familial non-BRCA1/BRCA2 breast tumors and mutation screening of a candidate locus on chromosome 17q11.2-12.

Maguire P, Holmberg K, Kost-Alimova M, Imreh S, Skoog L, Lindblom A.

Int J Mol Med. 2005 Jul;16(1):135-41.

PMID:
15942690
21.

Evolutionarily plastic regions at human 3p21.3 coincide with tumor breakpoints identified by the "elimination test".

Darai E, Kost-Alimova M, Kiss H, Kansoul H, Klein G, Imreh S.

Genomics. 2005 Jul;86(1):1-12.

PMID:
15913951
22.

Mitotic infidelity and centrosome duplication errors in cells overexpressing tripeptidyl-peptidase II.

Stavropoulou V, Xie J, Henriksson M, Tomkinson B, Imreh S, Masucci MG.

Cancer Res. 2005 Feb 15;65(4):1361-8.

23.

LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription.

Sharp TV, Munoz F, Bourboulia D, Presneau N, Darai E, Wang HW, Cannon M, Butcher DN, Nicholson AG, Klein G, Imreh S, Boshoff C.

Proc Natl Acad Sci U S A. 2004 Nov 23;101(47):16531-6. Epub 2004 Nov 12.

24.

Culture and expansion of the human embryonic stem cell line HS181, evaluated in a double-color system.

Imreh MP, Wolbank S, Unger C, Gertow K, Aints A, Szeles A, Imreh S, Hovatta O, Fried G, Dilber S, Ahrlund-Richter L.

Stem Cells Dev. 2004 Aug;13(4):337-43.

PMID:
15345126
25.

Interstitial deletions including chromosome 3 common eliminated region 1 (C3CER1) prevail in human solid tumors from 10 different tissues.

Petursdottir TE, Thorsteinsdottir U, Jonasson JG, Moller PH, Huiping C, Bjornsson J, Egilsson V, Imreh S, Ingvarsson S.

Genes Chromosomes Cancer. 2004 Nov;41(3):232-42.

PMID:
15334546
27.

Search for unknown tumor-antagonizing genes.

Imreh S, Klein G, Zabarovsky ER.

Genes Chromosomes Cancer. 2003 Dec;38(4):307-21. Review.

PMID:
14566849
28.

Coincidence of synteny breakpoints with malignancy-related deletions on human chromosome 3.

Kost-Alimova M, Kiss H, Fedorova L, Yang Y, Dumanski JP, Klein G, Imreh S.

Proc Natl Acad Sci U S A. 2003 May 27;100(11):6622-7. Epub 2003 May 8.

29.

Consistent downregulation of human lactoferrin gene, in the common eliminated region 1 on 3p21.3, following tumor growth in severe combined immunodeficient (SCID) mice.

Yang Y, Li J, Szeles A, Imreh MP, Kost-Alimova M, Kiss H, Kholodnyuk I, Fedorova L, Darai E, Klein G, Imreh S.

Cancer Lett. 2003 Mar 10;191(2):155-64.

PMID:
12618328
30.

Comparative human/murine sequence analysis of the common eliminated region 1 from human 3p21.3.

Kiss H, Darai E, Kiss C, Kost-Alimova M, Klein G, Dumanski JP, Imreh S.

Mamm Genome. 2002 Nov;13(11):646-55.

PMID:
12461651
31.

The microcell hybrid-based "elimination test" identifies a 1-Mb putative tumor-suppressor region at 3p22.2-p22.1 centromeric to the homozygous deletion region detected in lung cancer.

Kholodnyuk ID, Kost-Alimova M, Yang Y, Kiss H, Fedorova L, Klein G, Imreh S.

Genes Chromosomes Cancer. 2002 Jul;34(3):341-4.

PMID:
12007195
32.

Simian AIDS-related lymphoma growth in severe combined immunodeficiency mice is independent of karyotypic abnormalities or Bcl-6 mutations.

Castaños-Vélez E, Heiden T, Lindvall C, Capello D, Sandlund A, Imreh S, Blennow E, Andersson LC, Gaidano G, Nordenskjöld M, Biberfeld P.

AIDS Res Hum Retroviruses. 2002 Mar 20;18(5):383-90.

PMID:
11897040
33.

The transcriptional map of the common eliminated region 1 (C3CER1) in 3p21.3.

Kiss H, Yang Y, Kiss C, Andersson K, Klein G, Imreh S, Dumanski JP.

Eur J Hum Genet. 2002 Jan;10(1):52-61.

34.

Human wig-1, a p53 target gene that encodes a growth inhibitory zinc finger protein.

Hellborg F, Qian W, Mendez-Vidal C, Asker C, Kost-Alimova M, Wilhelm M, Imreh S, Wiman KG.

Oncogene. 2001 Sep 6;20(39):5466-74.

35.

The position of t(11;22)(q23;q11) constitutional translocation breakpoint is conserved among its carriers.

Tapia-Páez I, Kost-Alimova M, Hu P, Roe BA, Blennow E, Fedorova L, Imreh S, Dumanski JP.

Hum Genet. 2001 Aug;109(2):167-77.

PMID:
11511922
36.

The LZTFL1 gene is a part of a transcriptional map covering 250 kb within the common eliminated region 1 (C3CER1) in 3p21.3.

Kiss H, Kedra D, Kiss C, Kost-Alimova M, Yang Y, Klein G, Imreh S, Dumanski JP.

Genomics. 2001 Apr 1;73(1):10-9.

PMID:
11352561
37.

Similar regions of human chromosome 3 are eliminated from or retained in human/human and human/mouse microcell hybrids during tumor growth in severe combined immunodeficient (SCID) mice.

Yang Y, Kost-Alimova M, Ingvarsson S, Qianhui Q, Kiss H, Szeles A, Kholodnyuk I, Cuthbert A, Klein G, Imreh S.

Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1136-41.

39.

Fine mapping of the constitutional translocation t(11;22)(q23;q11).

Tapia-Páez I, O'Brien KP, Kost-Alimova M, Sahlén S, Kedra D, Bruder CE, Andersson B, Roe BA, Hu P, Imreh S, Blennow E, Dumanski JP.

Hum Genet. 2000 May;106(5):506-16.

PMID:
10914680
40.

Combined LOH/CGH analysis proves the existence of interstitial 3p deletions in renal cell carcinoma.

Alimov A, Kost-Alimova M, Liu J, Li C, Bergerheim U, Imreh S, Klein G, Zabarovsky ER.

Oncogene. 2000 Mar 9;19(11):1392-9.

41.

A novel gene containing LIM domains (LIMD1) is located within the common eliminated region 1 (C3CER1) in 3p21.3.

Kiss H, Kedra D, Yang Y, Kost-Alimova M, Kiss C, O'Brien KP, Fransson I, Klein G, Imreh S, Dumanski JP.

Hum Genet. 1999 Dec;105(6):552-9.

PMID:
10647888
42.

A 1-Mb PAC contig spanning the common eliminated region 1 (CER1) in microcell hybrid-derived SCID tumors.

Yang Y, Kiss H, Kost-Alimova M, Kedra D, Fransson I, Seroussi E, Li J, Szeles A, Kholodnyuk I, Imreh MP, Fodor K, Hadlaczky G, Klein G, Dumanski JP, Imreh S.

Genomics. 1999 Dec 1;62(2):147-55.

PMID:
10610706
43.

Genomic alterations in solid tumors. Introduction.

Imreh S.

Semin Cancer Biol. 1999 Aug;9(4):241-4. No abstract available.

PMID:
10448111
44.

TOM1 genes map to human chromosome 22q13.1 and mouse chromosome 8C1 and encode proteins similar to the endosomal proteins HGS and STAM.

Seroussi E, Kedra D, Kost-Alimova M, Sandberg-Nordqvist AC, Fransson I, Jacobs JF, Fu Y, Pan HQ, Roe BA, Imreh S, Dumanski JP.

Genomics. 1999 May 1;57(3):380-8.

PMID:
10329004
45.
46.

Stability of a functional murine satellite DNA-based artificial chromosome across mammalian species.

Telenius H, Szeles A, Keresö J, Csonka E, Praznovszky T, Imreh S, Maxwell A, Perez CF, Drayer JI, Hadlaczky G.

Chromosome Res. 1999;7(1):3-7.

PMID:
10219727
47.

Genomic structure and chromosomal localization of the mouse persyn gene.

Alimova-Kost MV, Ninkina NN, Imreh S, Gnuchev NV, Adu J, Davies AM, Buchman VL.

Genomics. 1999 Mar 1;56(2):224-7.

PMID:
10051410
48.

Assignment1 of phosphotriesterase-related gene (PTER) to human chromosome band 10p12 by in situ hybridization.

Alimova-Kost MV, Imreh S, Buchman VL, Ninkina NN.

Cytogenet Cell Genet. 1998;83(1-2):16-7. No abstract available.

PMID:
9925913
49.

The human LARGE gene from 22q12.3-q13.1 is a new, distinct member of the glycosyltransferase gene family.

Peyrard M, Seroussi E, Sandberg-Nordqvist AC, Xie YG, Han FY, Fransson I, Collins J, Dunham I, Kost-Alimova M, Imreh S, Dumanski JP.

Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):598-603.

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