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Items: 20

1.

Pharmacologic Characterization of AMG 334, a Potent and Selective Human Monoclonal Antibody against the Calcitonin Gene-Related Peptide Receptor.

Shi L, Lehto SG, Zhu DX, Sun H, Zhang J, Smith BP, Immke DC, Wild KD, Xu C.

J Pharmacol Exp Ther. 2016 Jan;356(1):223-31. doi: 10.1124/jpet.115.227793. Epub 2015 Nov 11.

PMID:
26559125
2.

Voltage-gated sodium channel function and expression in injured and uninjured rat dorsal root ganglia neurons.

Yin R, Liu D, Chhoa M, Li CM, Luo Y, Zhang M, Lehto SG, Immke DC, Moyer BD.

Int J Neurosci. 2016;126(2):182-92. doi: 10.3109/00207454.2015.1004172. Epub 2015 Apr 7.

PMID:
25562420
3.

AMG 580: a novel small molecule phosphodiesterase 10A (PDE10A) positron emission tomography tracer.

Chen H, Lester-Zeiner D, Shi J, Miller S, Glaus C, Hu E, Chen N, Able J, Biorn C, Wong J, Ma J, Michelsen K, Hill Della Puppa G, Kazules T, Dou HH, Talreja S, Zhao X, Chen A, Rumfelt S, Kunz RK, Ye H, Thiel OR, Williamson T, Davis C, Porter A, Immke D, Allen JR, Treanor J.

J Pharmacol Exp Ther. 2015 Feb;352(2):327-37. doi: 10.1124/jpet.114.220517. Epub 2014 Dec 11.

PMID:
25502803
4.

Regional, kinetic [(18)F]FDG PET imaging of a unilateral Parkinsonian animal model.

Silva MD, Glaus C, Hesterman JY, Hoppin J, Puppa GH, Kazules T, Orcutt KM, Germino M, Immke D, Miller S.

Am J Nucl Med Mol Imaging. 2013;3(2):129-41. Epub 2013 Mar 8.

5.

Rapid identification of a novel small molecule phosphodiesterase 10A (PDE10A) tracer.

Hu E, Ma J, Biorn C, Lester-Zeiner D, Cho R, Rumfelt S, Kunz RK, Nixey T, Michelsen K, Miller S, Shi J, Wong J, Hill Della Puppa G, Able J, Talreja S, Hwang DR, Hitchcock SA, Porter A, Immke D, Allen JR, Treanor J, Chen H.

J Med Chem. 2012 May 24;55(10):4776-87. doi: 10.1021/jm3002372. Epub 2012 May 11.

PMID:
22548439
6.

Identification of a potent, state-dependent inhibitor of Nav1.7 with oral efficacy in the formalin model of persistent pain.

Bregman H, Berry L, Buchanan JL, Chen A, Du B, Feric E, Hierl M, Huang L, Immke D, Janosky B, Johnson D, Li X, Ligutti J, Liu D, Malmberg A, Matson D, McDermott J, Miu P, Nguyen HN, Patel VF, Waldon D, Wilenkin B, Zheng XM, Zou A, McDonough SI, DiMauro EF.

J Med Chem. 2011 Jul 14;54(13):4427-45. doi: 10.1021/jm200018k. Epub 2011 Jun 2.

PMID:
21634377
7.

Structure-activity relationship (SAR) investigations of tetrahydroquinolines as BKCa agonists.

Gore VK, Ma VV, Yin R, Ligutti J, Immke D, Doherty EM, Norman MH.

Bioorg Med Chem Lett. 2010 Jun 15;20(12):3573-8. doi: 10.1016/j.bmcl.2010.04.125. Epub 2010 May 20.

PMID:
20493696
8.
9.

Species-specific pharmacology of Trichloro(sulfanyl)ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonists.

Klionsky L, Tamir R, Gao B, Wang W, Immke DC, Nishimura N, Gavva NR.

Mol Pain. 2007 Dec 17;3:39.

10.

Repeated administration of vanilloid receptor TRPV1 antagonists attenuates hyperthermia elicited by TRPV1 blockade.

Gavva NR, Bannon AW, Hovland DN Jr, Lehto SG, Klionsky L, Surapaneni S, Immke DC, Henley C, Arik L, Bak A, Davis J, Ernst N, Hever G, Kuang R, Shi L, Tamir R, Wang J, Wang W, Zajic G, Zhu D, Norman MH, Louis JC, Magal E, Treanor JJ.

J Pharmacol Exp Ther. 2007 Oct;323(1):128-37. Epub 2007 Jul 25.

PMID:
17652633
11.

The TRPV1 receptor and nociception.

Immke DC, Gavva NR.

Semin Cell Dev Biol. 2006 Oct;17(5):582-91. Epub 2006 Sep 24. Review.

PMID:
17196854
12.

ASIC3, an acid-sensing ion channel, is expressed in metaboreceptive sensory neurons.

Molliver DC, Immke DC, Fierro L, Paré M, Rice FL, McCleskey EW.

Mol Pain. 2005 Nov 23;1:35.

13.

AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties.

Gavva NR, Tamir R, Qu Y, Klionsky L, Zhang TJ, Immke D, Wang J, Zhu D, Vanderah TW, Porreca F, Doherty EM, Norman MH, Wild KD, Bannon AW, Louis JC, Treanor JJ.

J Pharmacol Exp Ther. 2005 Apr;313(1):474-84. Epub 2004 Dec 22.

PMID:
15615864
14.

ASIC3: a lactic acid sensor for cardiac pain.

Immke DC, McCleskey EW.

ScientificWorldJournal. 2001 Oct 5;1:510-2. Review.

15.

Protons open acid-sensing ion channels by catalyzing relief of Ca2+ blockade.

Immke DC, McCleskey EW.

Neuron. 2003 Jan 9;37(1):75-84.

16.

Lactate enhances the acid-sensing Na+ channel on ischemia-sensing neurons.

Immke DC, McCleskey EW.

Nat Neurosci. 2001 Sep;4(9):869-70.

PMID:
11528414
18.

Potassium-dependent changes in the conformation of the Kv2.1 potassium channel pore.

Immke D, Wood M, Kiss L, Korn SJ.

J Gen Physiol. 1999 Jun;113(6):819-36.

19.

Influence of non-P region domains on selectivity filter properties in voltage-gated K+ channels.

Immke D, Kiss L, LoTurco J, Korn SJ.

Receptors Channels. 1998;6(3):179-88.

PMID:
10100326
20.

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