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Items: 15

1.

99mTc-HYNIC-spermine for imaging polyamine transport system-positive tumours: preclinical evaluation.

Pesnel S, Guminski Y, Pillon A, Lerondel S, Imbert T, Guilbaud N, Kruczynski A, Bailly C, Le Pape A.

Eur J Nucl Med Mol Imaging. 2011 Oct;38(10):1832-41. doi: 10.1007/s00259-011-1857-2. Epub 2011 Jun 10.

PMID:
21660624
2.

A fluorescent biomarker of the polyamine transport system to select patients with AML for F14512 treatment.

Annereau JP, Brel V, Dumontet C, Guminski Y, Imbert T, Broussas M, Vispé S, Bréand S, Guilbaud N, Barret JM, Bailly C.

Leuk Res. 2010 Oct;34(10):1383-9. doi: 10.1016/j.leukres.2009.12.021. Epub 2010 Jan 22.

PMID:
20096930
3.

Preclinical activity of F14512, designed to target tumors expressing an active polyamine transport system.

Kruczynski A, Vandenberghe I, Pillon A, Pesnel S, Goetsch L, Barret JM, Guminski Y, Le Pape A, Imbert T, Bailly C, Guilbaud N.

Invest New Drugs. 2011 Feb;29(1):9-21. doi: 10.1007/s10637-009-9328-3. Epub 2009 Sep 24.

PMID:
19777159
4.

Synthesis of conjugated spermine derivatives with 7-nitrobenzoxadiazole (NBD), rhodamine and bodipy as new fluorescent probes for the polyamine transport system.

Guminski Y, Grousseaud M, Cugnasse S, Brel V, Annereau JP, Vispé S, Guilbaud N, Barret JM, Bailly C, Imbert T.

Bioorg Med Chem Lett. 2009 May 1;19(9):2474-7. doi: 10.1016/j.bmcl.2009.03.052. Epub 2009 Mar 18.

PMID:
19332372
5.

Antitumor activity of pyridoisoquinoline derivatives F91873 and F91874, novel multikinase inhibitors with activity against the anaplastic lymphoma kinase.

Kruczynski A, Mayer P, Marchand A, Vispé S, Fournier E, Annereau JP, Brel V, Barret JM, Delsol G, Imbert T, Fahy J, Bailly C.

Anticancer Drugs. 2009 Jun;20(5):364-72. doi: 10.1097/CAD.0b013e32832a2ed9.

PMID:
19322071
6.

F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system.

Barret JM, Kruczynski A, Vispé S, Annereau JP, Brel V, Guminski Y, Delcros JG, Lansiaux A, Guilbaud N, Imbert T, Bailly C.

Cancer Res. 2008 Dec 1;68(23):9845-53. doi: 10.1158/0008-5472.CAN-08-2748.

7.

alpha2-Adrenoreceptor antagonists.

Mayer P, Imbert T.

IDrugs. 2001 Jun;4(6):662-76.

PMID:
16001311
8.

Preclinical antitumour activity of F 11782, a novel dual catalytic inhibitor of topoisomerases.

Kruczynski A, Etiévant C, Perrin D, Imbert T, Colpaert F, Hill BT.

Br J Cancer. 2000 Dec;83(11):1516-24.

9.

New substituted 1-(2,3-dihydrobenzo[1, 4]dioxin-2-ylmethyl)piperidin-4-yl derivatives with alpha(2)-adrenoceptor antagonist activity.

Mayer P, Brunel P, Chaplain C, Piedecoq C, Calmel F, Schambel P, Chopin P, Wurch T, Pauwels PJ, Marien M, Vidaluc JL, Imbert T.

J Med Chem. 2000 Oct 5;43(20):3653-64.

PMID:
11020279
10.

F 11782, a novel epipodophylloid non-intercalating dual catalytic inhibitor of topoisomerases I and II with an original mechanism of action.

Perrin D, van Hille B, Barret JM, Kruczynski A, Etiévant C, Imbert T, Hill BT.

Biochem Pharmacol. 2000 Apr 1;59(7):807-19.

PMID:
10718339
11.

A new efficient synthesis of efaroxan.

Mayer P, Brunel P, Imbert T.

Bioorg Med Chem Lett. 1999 Oct 18;9(20):3021-2.

PMID:
10571167
12.

Synthesis and antitumor activity of new glycosides of epipodophyllotoxin, analogues of etoposide, and NK 611.

Daley L, Guminski Y, Demerseman P, Kruczynski A, Etiévant C, Imbert T, Hill BT, Monneret C.

J Med Chem. 1998 Nov 5;41(23):4475-85.

PMID:
9804687
13.

Requirements for P-glycoprotein recognition based on structure-activity relationships in the podophyllotoxin series.

Etievant C, Schambel P, Guminski Y, Barret JM, Imbert T, Hill BT.

Anticancer Drug Des. 1998 Jun;13(4):317-36.

PMID:
9627671
14.

Discovery of podophyllotoxins.

Imbert TF.

Biochimie. 1998 Mar;80(3):207-22.

PMID:
9615861
15.

CRE 10904 [2-(p-fluorophenoxy), 1-(o-hydroxyphenyl)-ethane]: a new diuretic and antihypertensive drug acting by in vivo sulfation.

Garay RP, Labaune JP, Mesangeau D, Nazaret C, Imbert T, Moinet G.

J Pharmacol Exp Ther. 1990 Nov;255(2):415-22.

PMID:
2243333

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