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Histone acetyltransferase PCAF is involved in transactivation of Bcl-6 and Pax5 genes in immature B cells.

Kikuchi H, Nakayama M, Kuribayashi F, Mimuro H, Imajoh-Ohmi S, Nishitoh H, Nakayama T.

Biochem Biophys Res Commun. 2015 Nov 20;467(3):509-13. doi: 10.1016/j.bbrc.2015.10.011. Epub 2015 Oct 9.


Mammalian Bcnt/Cfdp1, a potential epigenetic factor characterized by an acidic stretch in the disordered N-terminal and Ser250 phosphorylation in the conserved C-terminal regions.

Iwashita S, Suzuki T, Yasuda T, Nakashima K, Sakamoto T, Kohno T, Takahashi I, Kobayashi T, Ohno-Iwashita Y, Imajoh-Ohmi S, Song SY, Dohmae N.

Biosci Rep. 2015 Jun 12;35(4). pii: e00228. doi: 10.1042/BSR20150111.


Paired box gene 5 isoforms A and B have different functions in transcriptional regulation of B cell development-related genes in immature B cells.

Kikuchi H, Nakayama M, Kuribayashi F, Mimuro H, Imajoh-Ohmi S, Nishitoh H, Takami Y, Nakayama T.

Microbiol Immunol. 2015 Jul;59(7):426-31. doi: 10.1111/1348-0421.12272.


Lack of GCN5 remarkably enhances the resistance against prolonged endoplasmic reticulum stress-induced apoptosis through up-regulation of Bcl-2 gene expression.

Kikuchi H, Kuribayashi F, Mimuro H, Imajoh-Ohmi S, Nakayama M, Takami Y, Nishitoh H, Nakayama T.

Biochem Biophys Res Commun. 2015 Aug 7;463(4):870-5. doi: 10.1016/j.bbrc.2015.06.027. Epub 2015 Jun 15.


Efficient inhibition of tumor angiogenesis and growth by a synthetic peptide blocking S100A4-methionine aminopeptidase 2 interaction.

Ochiya T, Takenaga K, Asagiri M, Nakano K, Satoh H, Watanabe T, Imajoh-Ohmi S, Endo H.

Mol Ther Methods Clin Dev. 2015 Apr 1;2:15008. doi: 10.1038/mtm.2015.8. eCollection 2015.


Histone acetyltransferase p300/CBP-associated factor is an effective suppressor of secretory immunoglobulin synthesis in immature B cells.

Kikuchi H, Nakayama M, Kawai C, Kuribayashi F, Mimuro H, Imajoh-Ohmi S, Nishitoh H, Takami Y, Nakayama T.

Microbiol Immunol. 2015 Apr;59(4):243-7. doi: 10.1111/1348-0421.12237.


LAP degradation product reflects plasma kallikrein-dependent TGF-β activation in patients with hepatic fibrosis.

Hara M, Kirita A, Kondo W, Matsuura T, Nagatsuma K, Dohmae N, Ogawa S, Imajoh-Ohmi S, Friedman SL, Rifkin DB, Kojima S.

Springerplus. 2014 May 1;3:221. doi: 10.1186/2193-1801-3-221. eCollection 2014.


GCN5 is involved in regulation of immunoglobulin heavy chain gene expression in immature B cells.

Kikuchi H, Nakayama M, Kuribayashi F, Imajoh-Ohmi S, Nishitoh H, Takami Y, Nakayama T.

Gene. 2014 Jul 1;544(1):19-24. doi: 10.1016/j.gene.2014.04.030. Epub 2014 Apr 18.


Protein kinase Cθ gene expression is oppositely regulated by GCN5 and EBF1 in immature B cells.

Kikuchi H, Nakayama M, Kuribayashi F, Imajoh-Ohmi S, Nishitoh H, Takami Y, Nakayama T.

FEBS Lett. 2014 May 2;588(9):1739-42. doi: 10.1016/j.febslet.2014.03.025. Epub 2014 Mar 19.


Centrosomal BRCA2 is a target protein of membrane type-1 matrix metalloproteinase (MT1-MMP).

Wali N, Hosokawa K, Malik S, Saito H, Miyaguchi K, Imajoh-Ohmi S, Miki Y, Nakanishi A.

Biochem Biophys Res Commun. 2014 Jan 24;443(4):1148-54. doi: 10.1016/j.bbrc.2013.12.103. Epub 2013 Dec 30.


Down-regulation of Fas-mediated apoptosis by plasma transglutaminase factor XIII that catalyzes fetal-specific cross-link of the Fas molecule.

Kikuchi H, Kuribayashi F, Imajoh-Ohmi S.

Biochem Biophys Res Commun. 2014 Jan 3;443(1):13-7. doi: 10.1016/j.bbrc.2013.10.163. Epub 2013 Nov 8.


GCN5 is essential for IRF-4 gene expression followed by transcriptional activation of Blimp-1 in immature B cells.

Kikuchi H, Nakayama M, Kuribayashi F, Imajoh-Ohmi S, Nishitoh H, Takami Y, Nakayama T.

J Leukoc Biol. 2014 Mar;95(3):399-404. doi: 10.1189/jlb.0413232. Epub 2013 Sep 26.


GCN5 protects vertebrate cells against UV-irradiation via controlling gene expression of DNA polymerase η.

Kikuchi H, Kuribayashi F, Imajoh-Ohmi S, Nishitoh H, Takami Y, Nakayama T.

J Biol Chem. 2012 Nov 16;287(47):39842-9. doi: 10.1074/jbc.M112.406389. Epub 2012 Oct 2.


Two novel heat-soluble protein families abundantly expressed in an anhydrobiotic tardigrade.

Yamaguchi A, Tanaka S, Yamaguchi S, Kuwahara H, Takamura C, Imajoh-Ohmi S, Horikawa DD, Toyoda A, Katayama T, Arakawa K, Fujiyama A, Kubo T, Kunieda T.

PLoS One. 2012;7(8):e44209. doi: 10.1371/journal.pone.0044209. Epub 2012 Aug 28.


Sorting nexin 27 interacts with multidrug resistance-associated protein 4 (MRP4) and mediates internalization of MRP4.

Hayashi H, Naoi S, Nakagawa T, Nishikawa T, Fukuda H, Imajoh-Ohmi S, Kondo A, Kubo K, Yabuki T, Hattori A, Hirouchi M, Sugiyama Y.

J Biol Chem. 2012 Apr 27;287(18):15054-65. doi: 10.1074/jbc.M111.337931. Epub 2012 Mar 12.


The high-affinity choline transporter CHT1 is regulated by the ubiquitin ligase Nedd4-2.

Yamada H, Imajoh-Ohmi S, Haga T.

Biomed Res. 2012 Feb;33(1):1-8.


GCN5 regulates the activation of PI3K/Akt survival pathway in B cells exposed to oxidative stress via controlling gene expressions of Syk and Btk.

Kikuchi H, Kuribayashi F, Takami Y, Imajoh-Ohmi S, Nakayama T.

Biochem Biophys Res Commun. 2011 Feb 25;405(4):657-61. doi: 10.1016/j.bbrc.2011.01.088. Epub 2011 Jan 31.


BRCA2 interacts with the cytoskeletal linker protein plectin to form a complex controlling centrosome localization.

Niwa T, Saito H, Imajoh-ohmi S, Kaminishi M, Seto Y, Miki Y, Nakanishi A.

Cancer Sci. 2009 Nov;100(11):2115-25. doi: 10.1111/j.1349-7006.2009.01282.x. Epub 2009 Jul 8.


Proteomic analysis of protein complexes in human SH-SY5Y neuroblastoma cells by using blue-native gel electrophoresis: an increase in lamin A/C associated with heat shock protein 90 in response to 6-hydroxydopamine-induced oxidative stress.

Nakamura M, Morisawa H, Imajoh-Ohmi S, Takamura C, Fukuda H, Toda T.

Exp Gerontol. 2009 Jun-Jul;44(6-7):375-82. doi: 10.1016/j.exger.2009.02.009. Epub 2009 Mar 3.


Cell adhesion markedly increases lucigenin-enhanced chemiluminescence of the phagocyte NADPH oxidase.

Kuribayashi F, Tsuruta S, Yamazaki T, Nunoi H, Imajoh-Ohmi S, Kanegasaki S, Nakamura M.

Genes Cells. 2008 Dec;13(12):1249-56. doi: 10.1111/j.1365-2443.2008.01241.x. Epub 2008 Nov 19.


Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways.

Arimoto K, Fukuda H, Imajoh-Ohmi S, Saito H, Takekawa M.

Nat Cell Biol. 2008 Nov;10(11):1324-32. doi: 10.1038/ncb1791. Epub 2008 Oct 5.


Novel antiangiogenic pathway of thrombospondin-1 mediated by suppression of the cell cycle.

Yamauchi M, Imajoh-Ohmi S, Shibuya M.

Cancer Sci. 2007 Sep;98(9):1491-7. Epub 2007 Jul 26.


Protein kinase C epsilon phosphorylates keratin 8 at Ser8 and Ser23 in GH4C1 cells stimulated by thyrotropin-releasing hormone.

Akita Y, Kawasaki H, Imajoh-Ohmi S, Fukuda H, Ohno S, Hirano H, Ono Y, Yonekawa H.

FEBS J. 2007 Jul;274(13):3270-85. Epub 2007 Jun 6.


Autoantibodies against glial fibrillary acidic protein (GFAP) in cerebrospinal fluids from Pug dogs with necrotizing meningoencephalitis.

Shibuya M, Matsuki N, Fujiwara K, Imajoh-Ohmi S, Fukuda H, Pham NT, Tamahara S, Ono K.

J Vet Med Sci. 2007 Mar;69(3):241-5.


Interference with BRCA2, which localizes to the centrosome during S and early M phase, leads to abnormal nuclear division.

Nakanishi A, Han X, Saito H, Taguchi K, Ohta Y, Imajoh-Ohmi S, Miki Y.

Biochem Biophys Res Commun. 2007 Mar 30;355(1):34-40. Epub 2007 Jan 26.


Role(s) of nucleoli and phosphorylation of ribosomal protein S6 and/or HSP27 in the regulation of muscle mass.

Kawano F, Matsuoka Y, Oke Y, Higo Y, Terada M, Wang XD, Nakai N, Fukuda H, Imajoh-Ohmi S, Ohira Y.

Am J Physiol Cell Physiol. 2007 Jul;293(1):C35-44. Epub 2006 Dec 20.


Identification of phosphoproteins associated with maintenance of transformed state in temperature-sensitive Rous sarcoma-virus infected cells by proteomic analysis.

Yamaoka K, Imajoh-Ohmi S, Fukuda H, Akita Y, Kurosawa K, Yamamoto Y, Sanai Y.

Biochem Biophys Res Commun. 2006 Jul 7;345(3):1240-6. Epub 2006 May 15.


Assembly of the type III secretion apparatus of enteropathogenic Escherichia coli.

Ogino T, Ohno R, Sekiya K, Kuwae A, Matsuzawa T, Nonaka T, Fukuda H, Imajoh-Ohmi S, Abe A.

J Bacteriol. 2006 Apr;188(8):2801-11.


Fibulin-4 is a target of autoimmunity predominantly in patients with osteoarthritis.

Xiang Y, Sekine T, Nakamura H, Imajoh-Ohmi S, Fukuda H, Yudoh K, Masuko-Hongo K, Nishioka K, Kato T.

J Immunol. 2006 Mar 1;176(5):3196-204.


BopC is a novel type III effector secreted by Bordetella bronchiseptica and has a critical role in type III-dependent necrotic cell death.

Kuwae A, Matsuzawa T, Ishikawa N, Abe H, Nonaka T, Fukuda H, Imajoh-Ohmi S, Abe A.

J Biol Chem. 2006 Mar 10;281(10):6589-600. Epub 2006 Jan 4.


The superoxide-producing NAD(P)H oxidase Nox4 in the nucleus of human vascular endothelial cells.

Kuroda J, Nakagawa K, Yamasaki T, Nakamura K, Takeya R, Kuribayashi F, Imajoh-Ohmi S, Igarashi K, Shibata Y, Sueishi K, Sumimoto H.

Genes Cells. 2005 Dec;10(12):1139-51.


Lysophosphatidic acid cooperates with EGF in inducing branching morphogenesis of embryonic mouse salivary epithelium.

Noguchi Y, Okamoto A, Kasama T, Imajoh-Ohmi S, Karatsu T, Nogawa H.

Dev Dyn. 2006 Feb;235(2):403-10.


Carbonic anhydrase II is a tumor vessel endothelium-associated antigen targeted by dendritic cell therapy.

Yoshiura K, Nakaoka T, Nishishita T, Sato K, Yamamoto A, Shimada S, Saida T, Kawakami Y, Takahashi TA, Fukuda H, Imajoh-Ohmi S, Oyaizu N, Yamashita N.

Clin Cancer Res. 2005 Nov 15;11(22):8201-7.


Cleavage at the carboxyl-terminus of Ku80 during apoptosis in human Jurkat T cells.

Kato M, Nonaka T, Imajoh-Ohmi S.

J Biochem. 2005 Jun;137(6):685-92.


Cleavage of nonmuscle myosin heavy chain-A during apoptosis in human Jurkat T cells.

Kato M, Fukuda H, Nonaka T, Imajoh-Ohmi S.

J Biochem. 2005 Feb;137(2):157-66.


Membrane binding properties and terminal residues of the mature hepatitis C virus capsid protein in insect cells.

Ogino T, Fukuda H, Imajoh-Ohmi S, Kohara M, Nomoto A.

J Virol. 2004 Nov;78(21):11766-77.


[Peptide chemical synthesis].

Fukuda H, Imajoh-Ohmi S.

Tanpakushitsu Kakusan Koso. 2004 Aug;49(11 Suppl):1527-33. Review. Japanese. No abstract available.


LPS-induced apoptosis is dependent upon mitochondrial dysfunction.

Kuwabara T, Imajoh-Ohmi S.

Apoptosis. 2004 Jul;9(4):467-74.


Proteomic surveillance of autoimmunity in osteoarthritis: identification of triosephosphate isomerase as an autoantigen in patients with osteoarthritis.

Xiang Y, Sekine T, Nakamura H, Imajoh-Ohmi S, Fukuda H, Nishioka K, Kato T.

Arthritis Rheum. 2004 May;50(5):1511-21.


Sustained calpain activation associated with lysosomal rupture executes necrosis of the postischemic CA1 neurons in primates.

Yamashima T, Tonchev AB, Tsukada T, Saido TC, Imajoh-Ohmi S, Momoi T, Kominami E.

Hippocampus. 2003;13(7):791-800.


Oxidative stress in the pathogenesis of thoracic aortic aneurysm: protective role of statin and angiotensin II type 1 receptor blocker.

Ejiri J, Inoue N, Tsukube T, Munezane T, Hino Y, Kobayashi S, Hirata K, Kawashima S, Imajoh-Ohmi S, Hayashi Y, Yokozaki H, Okita Y, Yokoyama M.

Cardiovasc Res. 2003 Oct 1;59(4):988-96.


Shigella-induced necrosis and apoptosis of U937 cells and J774 macrophages.

Nonaka T, Kuwabara T, Mimuro H, Kuwae A, Imajoh-Ohmi S.

Microbiology. 2003 Sep;149(Pt 9):2513-27.


Reveromycin A inhibits antigen receptor-mediated antigen presentation by B lymphoma cells via its effect on intracellular trafficking of the antigen.

Tanaka Y, Ishikawa F, Osada H, Imajoh-Ohmi S, Uchida T, Kakiuchi T.

J Antibiot (Tokyo). 2002 Oct;55(10):904-13.


Superoxide generation in directional coronary atherectomy specimens of patients with angina pectoris: important role of NAD(P)H oxidase.

Azumi H, Inoue N, Ohashi Y, Terashima M, Mori T, Fujita H, Awano K, Kobayashi K, Maeda K, Hata K, Shinke T, Kobayashi S, Hirata K, Kawashima S, Itabe H, Hayashi Y, Imajoh-Ohmi S, Itoh H, Yokoyama M.

Arterioscler Thromb Vasc Biol. 2002 Nov 1;22(11):1838-44.


Characterization of mineral deposits formed in cultures of a hamster tartrate-resistant acid phosphatase (TRAP) and alkaline phosphatase (ALP) double-positive cell line (CCP).

Sakiyama H, Nonaka T, Masuda R, Inoue N, Kuboki Y, Iijima M, Hirabayasi Y, Takahagi M, Yoshida K, Kuriiwa K, Yoshida M, Imajoh-Ohmi S.

Cell Tissue Res. 2002 Aug;309(2):269-79. Epub 2002 Jul 5.


Cloning of hamster type XVII collagen cDNA, and pathogenesis of anti-type XVII collagen antibody and complement in hamster bullous pemphigoid.

Yamamoto K, Inoue N, Masuda R, Fujimori A, Saito T, Imajoh-Ohmi S, Shinkai H, Sakiyama H.

J Invest Dermatol. 2002 Mar;118(3):485-92.


Induction of phagocyte oxidase components during human myeloid differentiation: independent protein expression and discrepancy with the function.

Inoue Y, Yagisawa M, Saeki K, Imajoh-Ohmi S, Kanegasaki S, Yuo A.

Biosci Biotechnol Biochem. 2001 Nov;65(11):2581-4.

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