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Items: 29

1.

Age- and gender-specific incidence of new asthma diagnosis from childhood to late adulthood.

Honkamäki J, Hisinger-Mölkänen H, Ilmarinen P, Piirilä P, Tuomisto LE, Andersén H, Huhtala H, Sovijärvi A, Backman H, Lundbäck B, Rönmark E, Lehtimäki L, Kankaanranta H.

Respir Med. 2019 Jul - Aug;154:56-62. doi: 10.1016/j.rmed.2019.06.003. Epub 2019 Jun 8.

PMID:
31212122
2.

Cumulative effect of smoking on disease burden and multimorbidity in adult-onset asthma.

Tommola M, Ilmarinen P, Tuomisto LE, Lehtimäki L, Niemelä O, Nieminen P, Kankaanranta H.

Eur Respir J. 2019 Sep 5;54(3). pii: 1801580. doi: 10.1183/13993003.01580-2018. Print 2019 Sep. No abstract available.

PMID:
31048351
3.

YKL-40 and adult-onset asthma: Elevated levels in clusters with poorest outcome.

Ilmarinen P, Tuomisto LE, Niemelä O, Hämäläinen M, Moilanen E, Kankaanranta H.

J Allergy Clin Immunol Pract. 2019 Sep - Oct;7(7):2466-2468.e3. doi: 10.1016/j.jaip.2019.03.043. Epub 2019 Apr 4. No abstract available.

4.

Transient Receptor Potential Ankyrin 1 Enhances Ovalbumin-Induced Acute Allergic Inflammation in Murine Models.

Moilanen LJ, Hämäläinen M, Ilmarinen P, Kankaanranta H, Nieminen RM, Moilanen E, Lehtimäki L.

Int Arch Allergy Immunol. 2019;178(3):238-247. doi: 10.1159/000494932. Epub 2019 Jan 30.

PMID:
30699406
5.

Immediate bronchodilator response in FEV1 as a diagnostic criterion for adult asthma.

Tuomisto LE, Ilmarinen P, Lehtimäki L, Tommola M, Kankaanranta H.

Eur Respir J. 2019 Feb 14;53(2). pii: 1800904. doi: 10.1183/13993003.00904-2018. Print 2019 Feb. Review.

PMID:
30464017
6.

Daily physical activity and lung function decline in adult-onset asthma: a 12-year follow-up study.

Loponen J, Ilmarinen P, Tuomisto LE, Niemelä O, Tommola M, Nieminen P, Lehtimäki L, Kankaanranta H.

Eur Clin Respir J. 2018 Oct 24;5(1):1533753. doi: 10.1080/20018525.2018.1533753. eCollection 2018.

7.

Prevalence of Patients Eligible for Anti-IL-5 Treatment in a Cohort of Adult-Onset Asthma.

Ilmarinen P, Tuomisto LE, Niemelä O, Kankaanranta H.

J Allergy Clin Immunol Pract. 2019 Jan;7(1):165-174.e4. doi: 10.1016/j.jaip.2018.05.032. Epub 2018 Jun 9.

8.

Inhaled corticosteroids and asthma control in adult-onset asthma: 12-year follow-up study.

Vähätalo I, Ilmarinen P, Tuomisto LE, Niemelä O, Kankaanranta H.

Respir Med. 2018 Apr;137:70-76. doi: 10.1016/j.rmed.2018.02.025. Epub 2018 Mar 2.

PMID:
29605216
9.

Concern of underdiagnosing asthma-COPD overlap syndrome if age limit of 40 years for asthma is used.

Tommola M, Ilmarinen P, Tuomisto LE, Kankaanranta H.

Eur Respir J. 2017 Aug 3;50(2). pii: 1700871. doi: 10.1183/13993003.00871-2017. Print 2017 Aug. No abstract available.

10.

Differences between asthma-COPD overlap syndrome and adult-onset asthma.

Tommola M, Ilmarinen P, Tuomisto LE, Lehtimäki L, Haanpää J, Niemelä O, Kankaanranta H.

Eur Respir J. 2017 May 1;49(5). pii: 1602383. doi: 10.1183/13993003.02383-2016. Print 2017 May.

11.

Cluster Analysis on Longitudinal Data of Patients with Adult-Onset Asthma.

Ilmarinen P, Tuomisto LE, Niemelä O, Tommola M, Haanpää J, Kankaanranta H.

J Allergy Clin Immunol Pract. 2017 Jul - Aug;5(4):967-978.e3. doi: 10.1016/j.jaip.2017.01.027. Epub 2017 Apr 25.

12.

The effect of smoking on lung function: a clinical study of adult-onset asthma.

Tommola M, Ilmarinen P, Tuomisto LE, Haanpää J, Kankaanranta T, Niemelä O, Kankaanranta H.

Eur Respir J. 2016 Nov;48(5):1298-1306. doi: 10.1183/13993003.00850-2016. Epub 2016 Sep 22.

13.

Age-specific incidence of new asthma diagnoses in Finland.

Kankaanranta H, Tuomisto LE, Ilmarinen P.

J Allergy Clin Immunol Pract. 2017 Jan - Feb;5(1):189-191.e3. doi: 10.1016/j.jaip.2016.08.015. Epub 2016 Oct 17. No abstract available.

PMID:
27765463
14.

Comorbidities and elevated IL-6 associate with negative outcome in adult-onset asthma.

Ilmarinen P, Tuomisto LE, Niemelä O, Danielsson J, Haanpää J, Kankaanranta T, Kankaanranta H.

Eur Respir J. 2016 Oct;48(4):1052-1062. doi: 10.1183/13993003.02198-2015. Epub 2016 Aug 18.

15.

A 12-year prognosis of adult-onset asthma: Seinäjoki Adult Asthma Study.

Tuomisto LE, Ilmarinen P, Niemelä O, Haanpää J, Kankaanranta T, Kankaanranta H.

Respir Med. 2016 Aug;117:223-9. doi: 10.1016/j.rmed.2016.06.017. Epub 2016 Jun 23.

16.

Emerging Comorbidities in Adult Asthma: Risks, Clinical Associations, and Mechanisms.

Kankaanranta H, Kauppi P, Tuomisto LE, Ilmarinen P.

Mediators Inflamm. 2016;2016:3690628. doi: 10.1155/2016/3690628. Epub 2016 Apr 26. Review.

17.

Phenotypes, Risk Factors, and Mechanisms of Adult-Onset Asthma.

Ilmarinen P, Tuomisto LE, Kankaanranta H.

Mediators Inflamm. 2015;2015:514868. doi: 10.1155/2015/514868. Epub 2015 Oct 11. Review.

18.

Monosodium iodoacetate-induced inflammation and joint pain are reduced in TRPA1 deficient mice--potential role of TRPA1 in osteoarthritis.

Moilanen LJ, Hämäläinen M, Nummenmaa E, Ilmarinen P, Vuolteenaho K, Nieminen RM, Lehtimäki L, Moilanen E.

Osteoarthritis Cartilage. 2015 Nov;23(11):2017-26. doi: 10.1016/j.joca.2015.09.008.

19.

Seinäjoki Adult Asthma Study (SAAS): a protocol for a 12-year real-life follow-up study of new-onset asthma diagnosed at adult age and treated in primary and specialised care.

Kankaanranta H, Ilmarinen P, Kankaanranta T, Tuomisto LE.

NPJ Prim Care Respir Med. 2015 Jun 25;25:15042. doi: 10.1038/npjpcrm.2015.42. No abstract available.

20.

Prognosis of new-onset asthma diagnosed at adult age.

Tuomisto LE, Ilmarinen P, Kankaanranta H.

Respir Med. 2015 Aug;109(8):944-54. doi: 10.1016/j.rmed.2015.05.001. Epub 2015 May 21. Review.

21.

The polyamine spermine promotes survival and activation of human eosinophils.

Ilmarinen P, Moilanen E, Erjefält JS, Kankaanranta H.

J Allergy Clin Immunol. 2015 Aug;136(2):482-4.e11. doi: 10.1016/j.jaci.2014.12.1922. Epub 2015 Jan 30. No abstract available.

PMID:
25649081
22.

Regulation of spontaneous eosinophil apoptosis-a neglected area of importance.

Ilmarinen P, Moilanen E, Kankaanranta H.

J Cell Death. 2014 Feb 10;7:1-9. doi: 10.4137/JCD.S13588. eCollection 2014. Review.

23.

Eosinophil intracellular signalling: apoptosis.

Ilmarinen P, Moilanen E, Kankaanranta H.

Methods Mol Biol. 2014;1178:71-80. doi: 10.1007/978-1-4939-1016-8_7.

PMID:
24986608
24.

Mitochondria in the center of human eosinophil apoptosis and survival.

Ilmarinen P, Moilanen E, Kankaanranta H.

Int J Mol Sci. 2014 Mar 5;15(3):3952-69. doi: 10.3390/ijms15033952. Review.

25.

Tumour necrosis factor-α regulates human eosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-κB and AP-1.

Kankaanranta H, Ilmarinen P, Zhang X, Adcock IM, Lahti A, Barnes PJ, Giembycz MA, Lindsay MA, Moilanen E.

PLoS One. 2014 Feb 28;9(2):e90298. doi: 10.1371/journal.pone.0090298. eCollection 2014.

26.

Enhanced expression of neuropeptide S (NPS) receptor in eosinophils from severe asthmatics and subjects with total IgE above 100IU/ml.

Ilmarinen P, James A, Moilanen E, Pulkkinen V, Daham K, Saarelainen S, Laitinen T, Dahlén SE, Kere J, Dahlén B, Kankaanranta H.

Peptides. 2014 Jan;51:100-9. doi: 10.1016/j.peptides.2013.10.030. Epub 2013 Nov 13.

PMID:
24239856
27.

Eosinophil apoptosis as a therapeutic target in allergic asthma.

Ilmarinen P, Kankaanranta H.

Basic Clin Pharmacol Toxicol. 2014 Jan;114(1):109-17. doi: 10.1111/bcpt.12163. Epub 2013 Nov 13. Review.

28.

Bacterial DNA delays human eosinophil apoptosis.

Ilmarinen P, Hasala H, Sareila O, Moilanen E, Kankaanranta H.

Pulm Pharmacol Ther. 2009 Jun;22(3):167-76. doi: 10.1016/j.pupt.2008.11.012. Epub 2008 Dec 6.

PMID:
19073274
29.

Antieosinophilic activity of orazipone.

Kankaanranta H, Ilmarinen P, Zhang X, Nissinen E, Moilanen E.

Mol Pharmacol. 2006 Jun;69(6):1861-70. Epub 2006 Mar 15.

PMID:
16540599

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