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Items: 19

1.

Modification of the cyclopropyl moiety of abacavir provides insight into the structure activity relationship between HLA-B*57:01 binding and T-cell activation.

Thomson PJ, Illing PT, Farrell J, Alhaidari M, Bell CC, Berry N, O'Neill PM, Purcell AW, Park KB, Naisbitt DJ.

Allergy. 2019 Sep 24. doi: 10.1111/all.14057. [Epub ahead of print]

PMID:
31549414
2.

Response to Comment on "A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands".

Faridi P, Li C, Ramarathinam SH, Illing PT, Mifsud NA, Ayala R, Song J, Gearing LJ, Croft NP, Purcell AW.

Sci Immunol. 2019 Aug 16;4(38). pii: eaaw8457. doi: 10.1126/sciimmunol.aaw8457.

PMID:
31420321
3.

Downregulation of MHC Class I Expression by Influenza A and B Viruses.

Koutsakos M, McWilliam HEG, Aktepe TE, Fritzlar S, Illing PT, Mifsud NA, Purcell AW, Rockman S, Reading PC, Vivian JP, Rossjohn J, Brooks AG, Mackenzie JM, Mintern JD, Villadangos JA, Nguyen THO, Kedzierska K.

Front Immunol. 2019 May 29;10:1158. doi: 10.3389/fimmu.2019.01158. eCollection 2019.

4.

HLA-associated antiepileptic drug-induced cutaneous adverse reactions.

Mullan KA, Anderson A, Illing PT, Kwan P, Purcell AW, Mifsud NA.

HLA. 2019 Jun;93(6):417-435. doi: 10.1111/tan.13530. Epub 2019 Apr 9. Review.

PMID:
30895730
5.

Human CD8+ T cell cross-reactivity across influenza A, B and C viruses.

Koutsakos M, Illing PT, Nguyen THO, Mifsud NA, Crawford JC, Rizzetto S, Eltahla AA, Clemens EB, Sant S, Chua BY, Wong CY, Allen EK, Teng D, Dash P, Boyd DF, Grzelak L, Zeng W, Hurt AC, Barr I, Rockman S, Jackson DC, Kotsimbos TC, Cheng AC, Richards M, Westall GP, Loudovaris T, Mannering SI, Elliott M, Tangye SG, Wakim LM, Rossjohn J, Vijaykrishna D, Luciani F, Thomas PG, Gras S, Purcell AW, Kedzierska K.

Nat Immunol. 2019 May;20(5):613-625. doi: 10.1038/s41590-019-0320-6. Epub 2019 Feb 18.

PMID:
30778243
6.

HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.

Illing PT, Pymm P, Croft NP, Hilton HG, Jojic V, Han AS, Mendoza JL, Mifsud NA, Dudek NL, McCluskey J, Parham P, Rossjohn J, Vivian JP, Purcell AW.

Nat Commun. 2018 Nov 8;9(1):4693. doi: 10.1038/s41467-018-07109-w.

7.

A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands.

Faridi P, Li C, Ramarathinam SH, Vivian JP, Illing PT, Mifsud NA, Ayala R, Song J, Gearing LJ, Hertzog PJ, Ternette N, Rossjohn J, Croft NP, Purcell AW.

Sci Immunol. 2018 Oct 12;3(28). pii: eaar3947. doi: 10.1126/sciimmunol.aar3947.

PMID:
30315122
8.

Employing proteomics in the study of antigen presentation: an update.

Ramarathinam SH, Croft NP, Illing PT, Faridi P, Purcell AW.

Expert Rev Proteomics. 2018 Aug;15(8):637-645. doi: 10.1080/14789450.2018.1509000. Epub 2018 Aug 13. Review.

PMID:
30080115
9.

Identification of Native and Posttranslationally Modified HLA-B*57:01-Restricted HIV Envelope Derived Epitopes Using Immunoproteomics.

Ramarathinam SH, Gras S, Alcantara S, Yeung AWS, Mifsud NA, Sonza S, Illing PT, Glaros EN, Center RJ, Thomas SR, Kent SJ, Ternette N, Purcell DFJ, Rossjohn J, Purcell AW.

Proteomics. 2018 Jun;18(12):e1700253. doi: 10.1002/pmic.201700253. Epub 2018 Apr 10.

PMID:
29437277
10.

The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C*06:02 molecule.

Mobbs JI, Illing PT, Dudek NL, Brooks AG, Baker DG, Purcell AW, Rossjohn J, Vivian JP.

J Biol Chem. 2017 Oct 20;292(42):17203-17215. doi: 10.1074/jbc.M117.806976. Epub 2017 Aug 30.

11.

The role of HLA genes in pharmacogenomics: unravelling HLA associated adverse drug reactions.

Illing PT, Purcell AW, McCluskey J.

Immunogenetics. 2017 Aug;69(8-9):617-630. doi: 10.1007/s00251-017-1007-5. Epub 2017 Jul 10. Review.

PMID:
28695285
12.

MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.

Pymm P, Illing PT, Ramarathinam SH, O'Connor GM, Hughes VA, Hitchen C, Price DA, Ho BK, McVicar DW, Brooks AG, Purcell AW, Rossjohn J, Vivian JP.

Nat Struct Mol Biol. 2017 Apr;24(4):387-394. doi: 10.1038/nsmb.3381. Epub 2017 Feb 20.

PMID:
28218747
13.

Allotype specific interactions of drugs and HLA molecules in hypersensitivity reactions.

Illing PT, Mifsud NA, Purcell AW.

Curr Opin Immunol. 2016 Oct;42:31-40. doi: 10.1016/j.coi.2016.05.003. Epub 2016 Jun 2. Review.

PMID:
27261882
14.

A comprehensive analysis of peptides presented by HLA-A1.

Giam K, Ayala-Perez R, Illing PT, Schittenhelm RB, Croft NP, Purcell AW, Dudek NL.

Tissue Antigens. 2015 Jun;85(6):492-6. doi: 10.1111/tan.12565. Epub 2015 Apr 16.

PMID:
25880248
15.

The cellular redox environment alters antigen presentation.

Trujillo JA, Croft NP, Dudek NL, Channappanavar R, Theodossis A, Webb AI, Dunstone MA, Illing PT, Butler NS, Fett C, Tscharke DC, Rossjohn J, Perlman S, Purcell AW.

J Biol Chem. 2014 Oct 3;289(40):27979-91. doi: 10.1074/jbc.M114.573402. Epub 2014 Aug 18.

16.

Human leukocyte antigen-associated drug hypersensitivity.

Illing PT, Vivian JP, Purcell AW, Rossjohn J, McCluskey J.

Curr Opin Immunol. 2013 Feb;25(1):81-9. doi: 10.1016/j.coi.2012.10.002. Epub 2012 Nov 8. Review.

PMID:
23141566
17.

Constitutive and inflammatory immunopeptidome of pancreatic β-cells.

Dudek NL, Tan CT, Gorasia DG, Croft NP, Illing PT, Purcell AW.

Diabetes. 2012 Nov;61(11):3018-25. doi: 10.2337/db11-1333. Epub 2012 Aug 7.

18.

Immune self-reactivity triggered by drug-modified HLA-peptide repertoire.

Illing PT, Vivian JP, Dudek NL, Kostenko L, Chen Z, Bharadwaj M, Miles JJ, Kjer-Nielsen L, Gras S, Williamson NA, Burrows SR, Purcell AW, Rossjohn J, McCluskey J.

Nature. 2012 Jun 28;486(7404):554-8. doi: 10.1038/nature11147.

PMID:
22722860
19.

Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor.

Reantragoon R, Kjer-Nielsen L, Patel O, Chen Z, Illing PT, Bhati M, Kostenko L, Bharadwaj M, Meehan B, Hansen TH, Godfrey DI, Rossjohn J, McCluskey J.

J Exp Med. 2012 Apr 9;209(4):761-74. doi: 10.1084/jem.20112095. Epub 2012 Mar 12.

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