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Items: 35

1.

Precision medicine meets the DNA damage response in pancreatic cancer.

Perkhofer L, Illing A, Gout J, Frappart PO, Kleger A.

Oncoscience. 2018 Feb 22;5(1-2):6-8. doi: 10.18632/oncoscience.392. eCollection 2018 Jan. No abstract available.

2.

Reprogramming to pluripotency does not require transition through a primitive streak-like state.

Raab S, Klingenstein M, Möller A, Illing A, Tosic J, Breunig M, Kuales G, Linta L, Seufferlein T, Arnold SJ, Kleger A, Liebau S.

Sci Rep. 2017 Nov 29;7(1):16543. doi: 10.1038/s41598-017-15187-x.

3.

Gene dosage reductions of Trf1 and/or Tin2 induce telomere DNA damage and lymphoma formation in aging mice.

Hartmann K, Illing A, Leithäuser F, Baisantry A, Quintanilla-Martinez L, Rudolph KL.

Leukemia. 2017 Dec;31(12):2853. doi: 10.1038/leu.2017.224. Epub 2017 Nov 10.

4.

Stem cell-derived organoids to model gastrointestinal facets of cystic fibrosis.

Hohwieler M, Perkhofer L, Liebau S, Seufferlein T, Müller M, Illing A, Kleger A.

United European Gastroenterol J. 2017 Aug;5(5):609-624. doi: 10.1177/2050640616670565. Epub 2016 Sep 21. Review.

5.

Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling.

Hohwieler M, Illing A, Hermann PC, Mayer T, Stockmann M, Perkhofer L, Eiseler T, Antony JS, Müller M, Renz S, Kuo CC, Lin Q, Sendler M, Breunig M, Kleiderman SM, Lechel A, Zenker M, Leichsenring M, Rosendahl J, Zenke M, Sainz B Jr, Mayerle J, Costa IG, Seufferlein T, Kormann M, Wagner M, Liebau S, Kleger A.

Gut. 2017 Mar;66(3):473-486. doi: 10.1136/gutjnl-2016-312423. Epub 2016 Sep 15.

6.

Tbx3 fosters pancreatic cancer growth by increased angiogenesis and activin/nodal-dependent induction of stemness.

Perkhofer L, Walter K, Costa IG, Carrasco MC, Eiseler T, Hafner S, Genze F, Zenke M, Bergmann W, Illing A, Hohwieler M, Köhntop R, Lin Q, Holzmann KH, Seufferlein T, Wagner M, Liebau S, Hermann PC, Kleger A, Müller M.

Stem Cell Res. 2016 Sep;17(2):367-378. doi: 10.1016/j.scr.2016.08.007. Epub 2016 Aug 10.

7.

"Miniguts" from plucked human hair meet Crohn's disease.

Hohwieler M, Renz S, Liebau S, Lin Q, Lechel A, Klaus J, Perkhofer L, Zenke M, Seufferlein T, Illing A, Müller M, Kleger A.

Z Gastroenterol. 2016 Aug;54(8):748-59. doi: 10.1055/s-0042-105520. Epub 2016 Jul 14.

PMID:
27415403
8.

Xpg limits the expansion of haematopoietic stem and progenitor cells after ionising radiation.

Avila AI, Illing A, Becker F, Maerz LD, Morita Y, Philipp M, Burkhalter MD.

Nucleic Acids Res. 2016 Jul 27;44(13):6252-61. doi: 10.1093/nar/gkw376. Epub 2016 May 2.

9.

A Dynamic Role of TBX3 in the Pluripotency Circuitry.

Russell R, Ilg M, Lin Q, Wu G, Lechel A, Bergmann W, Eiseler T, Linta L, Kumar P P, Klingenstein M, Adachi K, Hohwieler M, Sakk O, Raab S, Moon A, Zenke M, Seufferlein T, Schöler HR, Illing A, Liebau S, Kleger A.

Stem Cell Reports. 2015 Dec 8;5(6):1155-1170. doi: 10.1016/j.stemcr.2015.11.003.

10.

Cardiac-Specific Activation of IKK2 Leads to Defects in Heart Development and Embryonic Lethality.

Kraut B, Maier HJ, Kókai E, Fiedler K, Boettger T, Illing A, Kostin S, Walther P, Braun T, Wirth T.

PLoS One. 2015 Nov 5;10(11):e0141591. doi: 10.1371/journal.pone.0141591. eCollection 2015.

11.

Protein Kinase D2 Assembles a Multiprotein Complex at the Trans-Golgi Network to Regulate Matrix Metalloproteinase Secretion.

Eiseler T, Wille C, Koehler C, Illing A, Seufferlein T.

J Biol Chem. 2016 Jan 1;291(1):462-77. doi: 10.1074/jbc.M115.673582. Epub 2015 Oct 27.

12.

Gene dosage reductions of Trf1 and/or Tin2 induce telomere DNA damage and lymphoma formation in aging mice.

Hartmann K, Illing A, Leithäuser F, Baisantry A, Quintanilla-Martinez L, Rudolph KL.

Leukemia. 2016 Mar;30(3):749-53. doi: 10.1038/leu.2015.173. Epub 2015 Jul 2. No abstract available. Erratum in: Leukemia. 2017 Nov 10;:.

13.

TBX3 Directs Cell-Fate Decision toward Mesendoderm.

Weidgang CE, Russell R, Tata PR, Kühl SJ, Illing A, Müller M, Lin Q, Brunner C, Boeckers TM, Bauer K, Kartikasari AE, Guo Y, Radenz M, Bernemann C, Weiß M, Seufferlein T, Zenke M, Iacovino M, Kyba M, Schöler HR, Kühl M, Liebau S, Kleger A.

Stem Cell Reports. 2014 May 6;2(5):747. doi: 10.1016/j.stemcr.2014.04.011. Epub 2014 May 8. No abstract available.

14.

[Induced pluripotent stem cells. A new resource in modern medicine].

Liebau S, Stockmann M, Illing A, Seufferlein T, Kleger A.

Internist (Berl). 2014 Apr;55(4):460-9. doi: 10.1007/s00108-013-3397-2. Review. German.

PMID:
24553769
15.

TBX3 Directs Cell-Fate Decision toward Mesendoderm.

Weidgang CE, Russell R, Tata PR, Kühl SJ, Illing A, Müller M, Lin Q, Brunner C, Boeckers TM, Bauer K, Kartikasari AE, Guo Y, Radenz M, Bernemann C, Weiß M, Seufferlein T, Zenke M, Iacovino M, Kyba M, Schöler HR, Kühl M, Liebau S, Kleger A.

Stem Cell Reports. 2013 Aug 29;1(3):248-65. doi: 10.1016/j.stemcr.2013.08.002. eCollection 2013. Erratum in: Stem Cell Reports. 2014 May 6;2(5):747.

16.

Modelling human channelopathies using induced pluripotent stem cells: a comprehensive review.

Müller M, Seufferlein T, Illing A, Homann J.

Stem Cells Int. 2013;2013:496501. doi: 10.1155/2013/496501. Epub 2013 May 12.

17.

Definitive Endoderm Formation from Plucked Human Hair-Derived Induced Pluripotent Stem Cells and SK Channel Regulation.

Illing A, Stockmann M, Swamy Telugu N, Linta L, Russell R, Müller M, Seufferlein T, Liebau S, Kleger A.

Stem Cells Int. 2013;2013:360573. doi: 10.1155/2013/360573. Epub 2013 Apr 16.

18.

A novel splice variant of calcium and integrin-binding protein 1 mediates protein kinase D2-stimulated tumour growth by regulating angiogenesis.

Armacki M, Joodi G, Nimmagadda SC, de Kimpe L, Pusapati GV, Vandoninck S, Van Lint J, Illing A, Seufferlein T.

Oncogene. 2014 Feb 27;33(9):1167-80. doi: 10.1038/onc.2013.43. Epub 2013 Mar 18.

PMID:
23503467
19.

A hierarchy in reprogramming capacity in different tissue microenvironments: what we know and what we need to know.

Liebau S, Mahaddalkar PU, Kestler HA, Illing A, Seufferlein T, Kleger A.

Stem Cells Dev. 2013 Mar 1;22(5):695-706. doi: 10.1089/scd.2012.0461. Epub 2013 Jan 5. Review.

PMID:
23167697
20.

Substrate profile and metal-ion selectivity of human divalent metal-ion transporter-1.

Illing AC, Shawki A, Cunningham CL, Mackenzie B.

J Biol Chem. 2012 Aug 31;287(36):30485-96. doi: 10.1074/jbc.M112.364208. Epub 2012 Jun 26.

21.

Estradiol increases hematopoietic stem and progenitor cells independent of its actions on bone.

Illing A, Liu P, Ostermay S, Schilling A, de Haan G, Krust A, Amling M, Chambon P, Schinke T, Tuckermann JP.

Haematologica. 2012 Aug;97(8):1131-5. doi: 10.3324/haematol.2011.052456. Epub 2012 Feb 27.

22.

Zip14 is a complex broad-scope metal-ion transporter whose functional properties support roles in the cellular uptake of zinc and nontransferrin-bound iron.

Pinilla-Tenas JJ, Sparkman BK, Shawki A, Illing AC, Mitchell CJ, Zhao N, Liuzzi JP, Cousins RJ, Knutson MD, Mackenzie B.

Am J Physiol Cell Physiol. 2011 Oct;301(4):C862-71. doi: 10.1152/ajpcell.00479.2010. Epub 2011 Jun 8.

23.

Protein kinase D2 is an essential regulator of murine myoblast differentiation.

Kleger A, Loebnitz C, Pusapati GV, Armacki M, Müller M, Tümpel S, Illing A, Hartmann D, Brunner C, Liebau S, Rudolph KL, Adler G, Seufferlein T.

PLoS One. 2011 Jan 27;6(1):e14599. doi: 10.1371/journal.pone.0014599.

24.

Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor.

Rauch A, Seitz S, Baschant U, Schilling AF, Illing A, Stride B, Kirilov M, Mandic V, Takacz A, Schmidt-Ullrich R, Ostermay S, Schinke T, Spanbroek R, Zaiss MM, Angel PE, Lerner UH, David JP, Reichardt HM, Amling M, Schütz G, Tuckermann JP.

Cell Metab. 2010 Jun 9;11(6):517-31. doi: 10.1016/j.cmet.2010.05.005.

25.

Transport model of the human Na+-coupled L-ascorbic acid (vitamin C) transporter SVCT1.

Mackenzie B, Illing AC, Hediger MA.

Am J Physiol Cell Physiol. 2008 Feb;294(2):C451-9. Epub 2007 Dec 19.

26.

Analysis of a vesicular glutamate transporter (VGLUT2) supports a cell-leakage mode in addition to vesicular packaging.

Mackenzie B, Illing AC, Morris ME, Varoqui H, Erickson JD.

Neurochem Res. 2008 Feb;33(2):238-47. Epub 2007 Dec 13.

PMID:
18080752
27.

Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy.

Tuckermann JP, Kleiman A, Moriggl R, Spanbroek R, Neumann A, Illing A, Clausen BE, Stride B, Förster I, Habenicht AJ, Reichardt HM, Tronche F, Schmid W, Schütz G.

J Clin Invest. 2007 May;117(5):1381-90. Epub 2007 Apr 19.

28.

Significant genetic differentiation between Poland and Germany follows present-day political borders, as revealed by Y-chromosome analysis.

Kayser M, Lao O, Anslinger K, Augustin C, Bargel G, Edelmann J, Elias S, Heinrich M, Henke J, Henke L, Hohoff C, Illing A, Jonkisz A, Kuzniar P, Lebioda A, Lessig R, Lewicki S, Maciejewska A, Monies DM, Pawłowski R, Poetsch M, Schmid D, Schmidt U, Schneider PM, Stradmann-Bellinghausen B, Szibor R, Wegener R, Wozniak M, Zoledziewska M, Roewer L, Dobosz T, Ploski R.

Hum Genet. 2005 Sep;117(5):428-43. Epub 2005 Jun 16.

PMID:
15959808
29.

Investigation on the flow behavior of dispersions of solid triglyceride nanoparticles.

Illing A, Unruh T.

Int J Pharm. 2004 Oct 13;284(1-2):123-31.

PMID:
15454303
30.

Investigation on particle self-assembly in solid lipid-based colloidal drug carrier systems.

Illing A, Unruh T, Koch MH.

Pharm Res. 2004 Apr;21(4):592-7.

PMID:
15139515
31.

Crystallographic investigation of cetylpalmitate solid lipid nanoparticles.

Lukowski G, Kasbohm J, Pflegel P, Illing A, Wulff H.

Int J Pharm. 2000 Mar 10;196(2):201-5.

PMID:
10699718
32.

Possible risk considerations for toxic risk assessment.

Paul H, Illing A.

Hum Exp Toxicol. 1991 May;10(3):215-9.

PMID:
1678952
34.

Lipophilicity of acceptor substrate as a factor in "late foetal" rat liver microsomal UDP-glucuronosyltransferase activity.

Paul H, Illing A.

Biochem Pharmacol. 1980 Apr 1;29(7):999-1006. No abstract available.

PMID:
6770870
35.

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