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Items: 1 to 50 of 151

1.

Anifrolumab effects on rash and arthritis: impact of the type I interferon gene signature in the phase IIb MUSE study in patients with systemic lupus erythematosus.

Merrill JT, Furie R, Werth VP, Khamashta M, Drappa J, Wang L, Illei G, Tummala R.

Lupus Sci Med. 2018 Nov 26;5(1):e000284. doi: 10.1136/lupus-2018-000284. eCollection 2018.

2.

Type I interferon receptor blockade with anifrolumab corrects innate and adaptive immune perturbations of SLE.

Casey KA, Guo X, Smith MA, Wang S, Sinibaldi D, Sanjuan MA, Wang L, Illei GG, White WI.

Lupus Sci Med. 2018 Nov 22;5(1):e000286. doi: 10.1136/lupus-2018-000286. eCollection 2018. Erratum in: Lupus Sci Med. 2018 Dec 22;5(1):e000286corr1.

3.

Response to: 'Response to: 'Lupus Low Disease Activity State(LLDAS) attainment discriminates responders in a systemic lupus erythematosus trial: post-hocanalysis of the Phase IIb MUSE trial of anifrolumab' by Eric Morand et al' by Isenberg.

Morand EF, Trasieva T, Berglind A, Illei G, Tummala R.

Ann Rheum Dis. 2018 Oct 29. pii: annrheumdis-2018-214487. doi: 10.1136/annrheumdis-2018-214487. [Epub ahead of print] No abstract available.

PMID:
30373881
4.

Systemic Lupus Erythematosus (SLE) Responder Index response is associated with global benefit for patients with SLE.

Furie R, Wang L, Illei G, Drappa J.

Lupus. 2018 May;27(6):955-962. doi: 10.1177/0961203318758506. Epub 2018 Feb 20.

PMID:
29460699
5.

Lupus Low Disease Activity State (LLDAS) attainment discriminates responders in a systemic lupus erythematosus trial: post-hoc analysis of the Phase IIb MUSE trial of anifrolumab.

Morand EF, Trasieva T, Berglind A, Illei GG, Tummala R.

Ann Rheum Dis. 2018 May;77(5):706-713. doi: 10.1136/annrheumdis-2017-212504. Epub 2018 Feb 2.

6.

Anifrolumab, an Anti-Interferon-α Receptor Monoclonal Antibody, in Moderate-to-Severe Systemic Lupus Erythematosus.

Furie R, Khamashta M, Merrill JT, Werth VP, Kalunian K, Brohawn P, Illei GG, Drappa J, Wang L, Yoo S; CD1013 Study Investigators.

Arthritis Rheumatol. 2017 Feb;69(2):376-386. doi: 10.1002/art.39962.

7.

Late responses to adenoviral-mediated transfer of the aquaporin-1 gene for radiation-induced salivary hypofunction.

Alevizos I, Zheng C, Cotrim AP, Liu S, McCullagh L, Billings ME, Goldsmith CM, Tandon M, Helmerhorst EJ, Catalán MA, Danielides SJ, Perez P, Nikolov NP, Chiorini JA, Melvin JE, Oppenheim FG, Illei GG, Baum BJ.

Gene Ther. 2017 Mar;24(3):176-186. doi: 10.1038/gt.2016.87. Epub 2016 Dec 20.

8.

Immune reactivity after adenoviral-mediated aquaporin-1 cDNA transfer to human parotid glands.

Alevizos I, Zheng C, Cotrim AP, Goldsmith CM, McCullagh L, Berkowitz T, Strobl SL, Malyguine A, Kopp WC, Chiorini JA, Nikolov NP, Neely M, Illei GG, Baum BJ.

Oral Dis. 2017 Apr;23(3):337-346. doi: 10.1111/odi.12614. Epub 2017 Feb 8.

9.

Targeting the Ca(2+) Sensor STIM1 by Exosomal Transfer of Ebv-miR-BART13-3p is Associated with Sjögren's Syndrome.

Gallo A, Jang SI, Ong HL, Perez P, Tandon M, Ambudkar I, Illei G, Alevizos I.

EBioMedicine. 2016 Aug;10:216-26. doi: 10.1016/j.ebiom.2016.06.041. Epub 2016 Jun 29.

10.

Sifalimumab, an anti-interferon-α monoclonal antibody, in moderate to severe systemic lupus erythematosus: a randomised, double-blind, placebo-controlled study.

Khamashta M, Merrill JT, Werth VP, Furie R, Kalunian K, Illei GG, Drappa J, Wang L, Greth W; CD1067 study investigators.

Ann Rheum Dis. 2016 Nov;75(11):1909-1916. doi: 10.1136/annrheumdis-2015-208562. Epub 2016 Mar 23.

11.

X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome.

Liu K, Kurien BT, Zimmerman SL, Kaufman KM, Taft DH, Kottyan LC, Lazaro S, Weaver CA, Ice JA, Adler AJ, Chodosh J, Radfar L, Rasmussen A, Stone DU, Lewis DM, Li S, Koelsch KA, Igoe A, Talsania M, Kumar J, Maier-Moore JS, Harris VM, Gopalakrishnan R, Jonsson R, Lessard JA, Lu X, Gottenberg JE, Anaya JM, Cunninghame-Graham DS, Huang AJW, Brennan MT, Hughes P, Illei GG, Miceli-Richard C, Keystone EC, Bykerk VP, Hirschfield G, Xie G, Ng WF, Nordmark G, Eriksson P, Omdal R, Rhodus NL, Rischmueller M, Rohrer M, Segal BM, Vyse TJ, Wahren-Herlenius M, Witte T, Pons-Estel B, Alarcon-Riquelme ME, Guthridge JM, James JA, Lessard CJ, Kelly JA, Thompson SD, Gaffney PM, Montgomery CG, Edberg JC, Kimberly RP, Alarcón GS, Langefeld CL, Gilkeson GS, Kamen DL, Tsao BP, McCune WJ, Salmon JE, Merrill JT, Weisman MH, Wallace DJ, Utset TO, Bottinger EP, Amos CI, Siminovitch KA, Mariette X, Sivils KL, Harley JB, Scofield RH.

Arthritis Rheumatol. 2016 May;68(5):1290-1300. doi: 10.1002/art.39560.

12.

EULAR Sjögren's syndrome disease activity index (ESSDAI): a user guide.

Seror R, Bowman SJ, Brito-Zeron P, Theander E, Bootsma H, Tzioufas A, Gottenberg JE, Ramos-Casals M, Dörner T, Ravaud P, Vitali C, Mariette X, Asmussen K, Jacobsen S, Bartoloni E, Gerli R, Bijlsma JW, Kruize AA, Bombardieri S, Bookman A, Kallenberg C, Meiners P, Brun JG, Jonsson R, Caporali R, Carsons S, De Vita S, Del Papa N, Devauchelle V, Saraux A, Fauchais AL, Sibilia J, Hachulla E, Illei G, Isenberg D, Jones A, Manoussakis M, Mandl T, Jacobsson L, Demoulins F, Montecucco C, Ng WF, Nishiyama S, Omdal R, Parke A, Praprotnik S, Tomsic M, Price E, Scofield H, L Sivils K, Smolen J, Laqué RS, Steinfeld S, Sutcliffe N, Sumida T, Valesini G, Valim V, Vivino FB, Vollenweider C.

RMD Open. 2015 Feb 20;1(1):e000022. doi: 10.1136/rmdopen-2014-000022. eCollection 2015. Review.

13.

Elevated interleukin-10: a new cause of dyslipidemia leading to severe HDL deficiency.

Moraitis AG, Freeman LA, Shamburek RD, Wesley R, Wilson W, Grant CM, Price S, Demosky S, Thacker SG, Zarzour A, Hornung RL, Pucino F, Csako G, Yarboro C, McInnes IB, Kuroiwa T, Boumpas D, Rao VK, Illei GG, Remaley AT.

J Clin Lipidol. 2015 Jan-Feb;9(1):81-90. doi: 10.1016/j.jacl.2014.09.014. Epub 2014 Oct 5.

14.

Predominant Glandular Cholinergic Dysautonomia in Patients With Primary Sjögren's Syndrome.

Imrich R, Alevizos I, Bebris L, Goldstein DS, Holmes CS, Illei GG, Nikolov NP.

Arthritis Rheumatol. 2015 May;67(5):1345-52. doi: 10.1002/art.39044.

15.

Establishment of functional acinar-like cultures from human salivary glands.

Jang SI, Ong HL, Gallo A, Liu X, Illei G, Alevizos I.

J Dent Res. 2015 Feb;94(2):304-11. doi: 10.1177/0022034514559251. Epub 2014 Nov 21.

16.

The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.

Kottyan LC, Zoller EE, Bene J, Lu X, Kelly JA, Rupert AM, Lessard CJ, Vaughn SE, Marion M, Weirauch MT, Namjou B, Adler A, Rasmussen A, Glenn S, Montgomery CG, Hirschfield GM, Xie G, Coltescu C, Amos C, Li H, Ice JA, Nath SK, Mariette X, Bowman S; UK Primary Sjögren's Syndrome Registry, Rischmueller M, Lester S, Brun JG, Gøransson LG, Harboe E, Omdal R, Cunninghame-Graham DS, Vyse T, Miceli-Richard C, Brennan MT, Lessard JA, Wahren-Herlenius M, Kvarnström M, Illei GG, Witte T, Jonsson R, Eriksson P, Nordmark G, Ng WF; UK Primary Sjögren's Syndrome Registry, Anaya JM, Rhodus NL, Segal BM, Merrill JT, James JA, Guthridge JM, Scofield RH, Alarcon-Riquelme M, Bae SC, Boackle SA, Criswell LA, Gilkeson G, Kamen DL, Jacob CO, Kimberly R, Brown E, Edberg J, Alarcón GS, Reveille JD, Vilá LM, Petri M, Ramsey-Goldman R, Freedman BI, Niewold T, Stevens AM, Tsao BP, Ying J, Mayes MD, Gorlova OY, Wakeland W, Radstake T, Martin E, Martin J, Siminovitch K, Moser Sivils KL, Gaffney PM, Langefeld CD, Harley JB, Kaufman KM.

Hum Mol Genet. 2015 Jan 15;24(2):582-96. doi: 10.1093/hmg/ddu455. Epub 2014 Sep 8.

17.

Discovery and validation of novel microRNAs in Sjögren's syndrome salivary glands.

Gallo A, Tandon M, Illei G, Alevizos I.

Clin Exp Rheumatol. 2014 Sep-Oct;32(5):761-2. Epub 2014 Sep 5. No abstract available.

PMID:
25189219
18.

Autoreactive IgE is prevalent in systemic lupus erythematosus and is associated with increased disease activity and nephritis.

Dema B, Pellefigues C, Hasni S, Gault N, Jiang C, Ricks TK, Bonelli MM, Scheffel J, Sacré K, Jablonski M, Gobert D, Papo T, Daugas E, Illei G, Charles N, Rivera J.

PLoS One. 2014 Feb 28;9(2):e90424. doi: 10.1371/journal.pone.0090424. eCollection 2014.

19.

Reply: To PMID 23925905.

Golding A, Shavach EM, Hasni S, Illei G.

Arthritis Rheumatol. 2014 May;66(5):1403-4. doi: 10.1002/art.38377. No abstract available.

20.

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome.

Lessard CJ, Li H, Adrianto I, Ice JA, Rasmussen A, Grundahl KM, Kelly JA, Dozmorov MG, Miceli-Richard C, Bowman S, Lester S, Eriksson P, Eloranta ML, Brun JG, Gøransson LG, Harboe E, Guthridge JM, Kaufman KM, Kvarnström M, Jazebi H, Cunninghame Graham DS, Grandits ME, Nazmul-Hossain AN, Patel K, Adler AJ, Maier-Moore JS, Farris AD, Brennan MT, Lessard JA, Chodosh J, Gopalakrishnan R, Hefner KS, Houston GD, Huang AJ, Hughes PJ, Lewis DM, Radfar L, Rohrer MD, Stone DU, Wren JD, Vyse TJ, Gaffney PM, James JA, Omdal R, Wahren-Herlenius M, Illei GG, Witte T, Jonsson R, Rischmueller M, Rönnblom L, Nordmark G, Ng WF; UK Primary Sjögren's Syndrome Registry, Mariette X, Anaya JM, Rhodus NL, Segal BM, Scofield RH, Montgomery CG, Harley JB, Sivils KL.

Nat Genet. 2013 Nov;45(11):1284-92. doi: 10.1038/ng.2792. Epub 2013 Oct 6.

21.

Association of bone morphogenetic protein 6 with exocrine gland dysfunction in patients with Sjögren's syndrome and in mice.

Yin H, Cabrera-Perez J, Lai Z, Michael D, Weller M, Swaim WD, Liu X, Catalán MA, Rocha EM, Ismail N, Afione S, Rana NA, Di Pasquale G, Alevizos I, Ambudkar I, Illei GG, Chiorini JA.

Arthritis Rheum. 2013 Dec;65(12):3228-38. doi: 10.1002/art.38123.

22.

The percentage of FoxP3+Helios+ Treg cells correlates positively with disease activity in systemic lupus erythematosus.

Golding A, Hasni S, Illei G, Shevach EM.

Arthritis Rheum. 2013 Nov;65(11):2898-906. doi: 10.1002/art.38119. Erratum in: Arthritis Rheum. 2014 Jun;66(6):1671.

23.

miR-150 promotes renal fibrosis in lupus nephritis by downregulating SOCS1.

Zhou H, Hasni SA, Perez P, Tandon M, Jang SI, Zheng C, Kopp JB, Austin H 3rd, Balow JE, Alevizos I, Illei GG.

J Am Soc Nephrol. 2013 Jun;24(7):1073-87. doi: 10.1681/ASN.2012080849. Epub 2013 May 30.

24.

Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction.

Baum BJ, Alevizos I, Zheng C, Cotrim AP, Liu S, McCullagh L, Goldsmith CM, Burbelo PD, Citrin DE, Mitchell JB, Nottingham LK, Rudy SF, Van Waes C, Whatley MA, Brahim JS, Chiorini JA, Danielides S, Turner RJ, Patronas NJ, Chen CC, Nikolov NP, Illei GG.

Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19403-7. doi: 10.1073/pnas.1210662109. Epub 2012 Nov 5.

25.

Interleukin-17 cytokines are critical in development of fatal lupus glomerulonephritis.

Pisitkun P, Ha HL, Wang H, Claudio E, Tivy CC, Zhou H, Mayadas TN, Illei GG, Siebenlist U.

Immunity. 2012 Dec 14;37(6):1104-15. doi: 10.1016/j.immuni.2012.08.014. Epub 2012 Nov 1.

26.

Impact of anti-interleukin-6 receptor blockade on circulating T and B cell subsets in patients with systemic lupus erythematosus.

Shirota Y, Yarboro C, Fischer R, Pham TH, Lipsky P, Illei GG.

Ann Rheum Dis. 2013 Jan;72(1):118-28. doi: 10.1136/annrheumdis-2012-201310. Epub 2012 Aug 2.

PMID:
22858586
27.

The expression of APRIL in Sjogren's syndrome: aberrant expression of APRIL in the salivary gland.

Vosters JL, Roescher N, Polling EJ, Illei GG, Tak PP.

Rheumatology (Oxford). 2012 Sep;51(9):1557-62. doi: 10.1093/rheumatology/kes080. Epub 2012 May 4.

28.

The majority of microRNAs detectable in serum and saliva is concentrated in exosomes.

Gallo A, Tandon M, Alevizos I, Illei GG.

PLoS One. 2012;7(3):e30679. doi: 10.1371/journal.pone.0030679. Epub 2012 Mar 9.

29.

Adrenomedullary response to glucagon in patients with primary Sjögren's syndrome.

Imrich R, Nikolov NP, Bebris L, Alevizos I, Goldstein DS, Holmes CS, Illei GG.

Cell Mol Neurobiol. 2012 Jul;32(5):903-6. doi: 10.1007/s10571-011-9787-x. Epub 2012 Feb 18.

30.

TACI-Fc gene therapy improves autoimmune sialadenitis but not salivary gland function in non-obese diabetic mice.

Vosters JL, Roescher N, Illei GG, Chiorini JA, Tak PP.

Oral Dis. 2012 May;18(4):365-74. doi: 10.1111/j.1601-0825.2011.01885.x. Epub 2011 Dec 29.

31.

Temporal changes in salivary glands of non-obese diabetic mice as a model for Sjögren's syndrome.

Roescher N, Lodde BM, Vosters JL, Tak PP, Catalan MA, Illei GG, Chiorini JA.

Oral Dis. 2012 Jan;18(1):96-106. doi: 10.1111/j.1601-0825.2011.01852.x. Epub 2011 Sep 14.

32.

Helicobacter pylori and autoimmune diseases.

Hasni S, Ippolito A, Illei GG.

Oral Dis. 2011 Oct;17(7):621-7. doi: 10.1111/j.1601-0825.2011.01796.x. Epub 2011 Mar 29. Review.

33.

Deep sequencing of short RNAs reveals novel microRNAs in minor salivary glands of patients with Sjögren's syndrome.

Tandon M, Gallo A, Jang SI, Illei GG, Alevizos I.

Oral Dis. 2012 Mar;18(2):127-31. doi: 10.1111/j.1601-0825.2011.01849.x. Epub 2011 Sep 6.

34.

Current state and future directions of autologous hematopoietic stem cell transplantation in systemic lupus erythematosus.

Illei GG, Cervera R, Burt RK, Doria A, Hiepe F, Jayne D, Pavletic S, Martin T, Marmont A, Saccardi R, Voskuyl AE, Farge D.

Ann Rheum Dis. 2011 Dec;70(12):2071-4. doi: 10.1136/ard.2010.148049. Epub 2011 Aug 26.

35.

Microarray analysis of sexually dimorphic gene expression in human minor salivary glands.

Michael D, Soi S, Cabera-Perez J, Weller M, Alexander S, Alevizos I, Illei G, Chiorini J.

Oral Dis. 2011 Oct;17(7):653-61. doi: 10.1111/j.1601-0825.2011.01816.x. Epub 2011 Aug 8.

36.

Use of a novel virus detection assay to identify coronavirus HKU1 in the lungs of a hematopoietic stem cell transplant recipient with fatal pneumonia.

Uhlenhaut C, Cohen JI, Pavletic S, Illei G, Gea-Banacloche JC, Abu-Asab M, Krogmann T, Gubareva L, McClenahan S, Krause PR.

Transpl Infect Dis. 2012 Feb;14(1):79-85. doi: 10.1111/j.1399-3062.2011.00657.x. Epub 2011 Jul 12.

37.

Effect of soluble ICAM-1 on a Sjögren's syndrome-like phenotype in NOD mice is disease stage dependent.

Roescher N, Vosters JL, Yin H, Illei GG, Tak PP, Chiorini JA.

PLoS One. 2011 May 12;6(5):e19962. doi: 10.1371/journal.pone.0019962.

38.

MicroRNA expression profiles as biomarkers of minor salivary gland inflammation and dysfunction in Sjögren's syndrome.

Alevizos I, Alexander S, Turner RJ, Illei GG.

Arthritis Rheum. 2011 Feb;63(2):535-44. doi: 10.1002/art.30131.

39.

The non-muscle Myosin heavy chain 9 gene (MYH9) is not associated with lupus nephritis in African Americans.

Freedman BI, Edberg JC, Comeau ME, Murea M, Bowden DW, Divers J, Alarcón GS, Brown EE, McGwin G Jr, Kopp JB, Winkler CA, Nelson GW, Illei G, Petri M, Ramsey-Goldman R, Reveille JD, Vilá LM, Langefeld CD, Kimberly RP; PROFILE Study Group.

Am J Nephrol. 2010;32(1):66-72. doi: 10.1159/000314688. Epub 2010 Jun 7.

40.

MicroRNAs as biomarkers in rheumatic diseases.

Alevizos I, Illei GG.

Nat Rev Rheumatol. 2010 Jul;6(7):391-8. doi: 10.1038/nrrheum.2010.81. Epub 2010 Jun 1. Review.

41.

Basophils and the T helper 2 environment can promote the development of lupus nephritis.

Charles N, Hardwick D, Daugas E, Illei GG, Rivera J.

Nat Med. 2010 Jun;16(6):701-7. doi: 10.1038/nm.2159. Epub 2010 May 30.

42.

Peptide-based ELISAs are not sensitive and specific enough to detect muscarinic receptor type 3 autoantibodies in serum from patients with Sjogren's syndrome.

Roescher N, Kingman A, Shirota Y, Chiorini JA, Illei GG.

Ann Rheum Dis. 2011 Jan;70(1):235-6. doi: 10.1136/ard.2010.129049. Epub 2010 May 24.

43.

MicroRNAs in Sjögren's syndrome as a prototypic autoimmune disease.

Alevizos I, Illei GG.

Autoimmun Rev. 2010 Jul;9(9):618-21. doi: 10.1016/j.autrev.2010.05.009. Epub 2010 May 10. Review.

44.

Cytokines in Sjogren's syndrome: potential therapeutic targets.

Roescher N, Tak PP, Illei GG.

Ann Rheum Dis. 2010 Jun;69(6):945-8. doi: 10.1136/ard.2009.115378. Epub 2010 Apr 21.

45.

Rapid vision loss associated with fludarabine administration.

Bishop RJ, Ding X, Heller CK 3rd, Illei G, Caruso R, Cunningham D, Pavletic S, Chan CC.

Retina. 2010 Sep;30(8):1272-7. doi: 10.1097/IAE.0b013e3181d20589.

46.

Genetic association between methyl-CpG binding protein 2 (MECP2) and primary Sjogren's syndrome.

Cobb BL, Fei Y, Jonsson R, Bolstad AI, Brun JG, Rischmueller M, Lester SE, Witte T, Illei G, Brennan M, Bowman S, Moser KL, Harley JB, Sawalha AH.

Ann Rheum Dis. 2010 Sep;69(9):1731-2. doi: 10.1136/ard.2009.122903. Epub 2010 Mar 9. No abstract available.

47.

Tocilizumab in systemic lupus erythematosus: data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase I dosage-escalation study.

Illei GG, Shirota Y, Yarboro CH, Daruwalla J, Tackey E, Takada K, Fleisher T, Balow JE, Lipsky PE.

Arthritis Rheum. 2010 Feb;62(2):542-52. doi: 10.1002/art.27221.

48.

Transient detection of E1-containing adenovirus in saliva after the delivery of a first-generation adenoviral vector to human parotid gland.

Zheng C, Nikolov NP, Alevizos I, Cotrim AP, Liu S, McCullagh L, Chiorini JA, Illei GG, Baum BJ.

J Gene Med. 2010 Jan;12(1):3-10. doi: 10.1002/jgm.1416.

49.

Development of a gene transfer-based treatment for radiation-induced salivary hypofunction.

Baum BJ, Zheng C, Alevizos I, Cotrim AP, Liu S, McCullagh L, Goldsmith CM, McDermott N, Chiorini JA, Nikolov NP, Illei GG.

Oral Oncol. 2010 Jan;46(1):4-8. doi: 10.1016/j.oraloncology.2009.09.004. Epub 2009 Nov 4. Review.

50.

Sensitive and robust luminescent profiling of anti-La and other autoantibodies in Sjogren's syndrome.

Burbelo PD, Leahy HP, Issa AT, Groot S, Baraniuk JN, Nikolov NP, Illei GG, Iadarola MJ.

Autoimmunity. 2009 Sep;42(6):515-24. doi: 10.1080/08916930902911738.

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