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Items: 1 to 50 of 142

1.

Plasma MicroRNAs in Established Rheumatoid Arthritis Relate to Adiposity and Altered Plasma and Skeletal Muscle Cytokine and Metabolic Profiles.

Andonian BJ, Chou CH, Ilkayeva OR, Koves TR, Connelly MA, Kraus WE, Kraus VB, Huffman KM.

Front Immunol. 2019 Jun 27;10:1475. doi: 10.3389/fimmu.2019.01475. eCollection 2019.

2.

Effects of microbiota-directed foods in gnotobiotic animals and undernourished children.

Gehrig JL, Venkatesh S, Chang HW, Hibberd MC, Kung VL, Cheng J, Chen RY, Subramanian S, Cowardin CA, Meier MF, O'Donnell D, Talcott M, Spears LD, Semenkovich CF, Henrissat B, Giannone RJ, Hettich RL, Ilkayeva O, Muehlbauer M, Newgard CB, Sawyer C, Head RD, Rodionov DA, Arzamasov AA, Leyn SA, Osterman AL, Hossain MI, Islam M, Choudhury N, Sarker SA, Huq S, Mahmud I, Mostafa I, Mahfuz M, Barratt MJ, Ahmed T, Gordon JI.

Science. 2019 Jul 12;365(6449). pii: eaau4732. doi: 10.1126/science.aau4732.

PMID:
31296738
3.

Cellular energetics and mitochondrial uncoupling in canine aging.

Nicholatos JW, Robinette TM, Tata SVP, Yordy JD, Francisco AB, Platov M, Yeh TK, Ilkayeva OR, Huynh FK, Dokukin M, Volkov D, Weinstein MA, Boyko AR, Miller RA, Sokolov I, Hirschey MD, Libert S.

Geroscience. 2019 Apr;41(2):229-242. doi: 10.1007/s11357-019-00062-6. Epub 2019 Apr 1.

4.

Metabolites predict cardiovascular disease events in persons living with HIV: a pilot case-control study.

Okeke NL, Craig DM, Muehlbauer MJ, Ilkayeva O, Clement ME, Naggie S, Shah SH.

Metabolomics. 2018 Mar;14(3). pii: 23. doi: 10.1007/s11306-018-1318-z. Epub 2018 Jan 31.

5.

A Mitochondrial Progesterone Receptor Increases Cardiac Beta-Oxidation and Remodeling.

Dai Q, Likes CE 3rd, Luz AL, Mao L, Yeh JS, Wei Z, Kuchibhatla M, Ilkayeva OR, Koves TR, Price TM.

J Endocr Soc. 2019 Jan 3;3(2):446-467. doi: 10.1210/js.2018-00219. eCollection 2019 Feb 1.

6.

Respiratory Phenomics across Multiple Models of Protein Hyperacylation in Cardiac Mitochondria Reveals a Marginal Impact on Bioenergetics.

Fisher-Wellman KH, Draper JA, Davidson MT, Williams AS, Narowski TM, Slentz DH, Ilkayeva OR, Stevens RD, Wagner GR, Najjar R, Hirschey MD, Thompson JW, Olson DP, Kelly DP, Koves TR, Grimsrud PA, Muoio DM.

Cell Rep. 2019 Feb 5;26(6):1557-1572.e8. doi: 10.1016/j.celrep.2019.01.057.

7.

Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose.

Meyer JG, Softic S, Basisty N, Rardin MJ, Verdin E, Gibson BW, Ilkayeva O, Newgard CB, Kahn CR, Schilling B.

PLoS One. 2018 Dec 26;13(12):e0208973. doi: 10.1371/journal.pone.0208973. eCollection 2018.

8.

Maternal metabolites during pregnancy are associated with newborn outcomes and hyperinsulinaemia across ancestries.

Kadakia R, Nodzenski M, Talbot O, Kuang A, Bain JR, Muehlbauer MJ, Stevens RD, Ilkayeva OR, O'Neal SK, Lowe LP, Metzger BE, Newgard CB, Scholtens DM, Lowe WL Jr; HAPO Study Cooperative Research Group.

Diabetologia. 2019 Mar;62(3):473-484. doi: 10.1007/s00125-018-4781-1. Epub 2018 Nov 27.

PMID:
30483859
9.

Cord Blood Metabolites Associated with Newborn Adiposity and Hyperinsulinemia.

Kadakia R, Scholtens DM, Rouleau GW, Talbot O, Ilkayeva OR, George T, Josefson JL.

J Pediatr. 2018 Dec;203:144-149.e1. doi: 10.1016/j.jpeds.2018.07.056. Epub 2018 Sep 10.

PMID:
30213459
10.

N6-methyladenosine contributes to cellular phenotype in a genetically-defined model of breast cancer progression.

Fry NJ, Law BA, Ilkayeva OR, Carraway KR, Holley CL, Mansfield KD.

Oncotarget. 2018 Jul 27;9(58):31231-31243. doi: 10.18632/oncotarget.25782. eCollection 2018 Jul 27.

11.

Adverse Effects of Fenofibrate in Mice Deficient in the Protein Quality Control Regulator, CHIP.

Ravi S, Parry TL, Willis MS, Lockyer P, Patterson C, Bain JR, Stevens RD, Ilkayeva OR, Newgard CB, Schisler JC.

J Cardiovasc Dev Dis. 2018 Aug 15;5(3). pii: E43. doi: 10.3390/jcdd5030043.

12.

Age-Related Adverse Inflammatory and Metabolic Changes Begin Early in Adulthood.

Parker D, Sloane R, Pieper CF, Hall KS, Kraus VB, Kraus WE, Huebner JL, Ilkayeva OR, Bain JR, Newby LK, Cohen HJ, Morey MC.

J Gerontol A Biol Sci Med Sci. 2019 Feb 15;74(3):283-289. doi: 10.1093/gerona/gly121.

13.

Remodeling of the Acetylproteome by SIRT3 Manipulation Fails to Affect Insulin Secretion or β Cell Metabolism in the Absence of Overnutrition.

Peterson BS, Campbell JE, Ilkayeva O, Grimsrud PA, Hirschey MD, Newgard CB.

Cell Rep. 2018 Jul 3;24(1):209-223.e6. doi: 10.1016/j.celrep.2018.05.088.

14.

Dietary Patterns among Asian Indians Living in the United States Have Distinct Metabolomic Profiles That Are Associated with Cardiometabolic Risk.

Bhupathiraju SN, Guasch-Ferré M, Gadgil MD, Newgard CB, Bain JR, Muehlbauer MJ, Ilkayeva OR, Scholtens DM, Hu FB, Kanaya AM, Kandula NR.

J Nutr. 2018 Jul 1;148(7):1150-1159. doi: 10.1093/jn/nxy074.

15.

Improvement in insulin resistance after gastric bypass surgery is correlated with a decline in plasma 2-hydroxybutyric acid.

Shantavasinkul PC, Muehlbauer MJ, Bain JR, Ilkayeva OR, Craig DM, Newgard CB, Svetkey LP, Shah SH, Torquati A.

Surg Obes Relat Dis. 2018 Aug;14(8):1126-1132. doi: 10.1016/j.soard.2018.03.033. Epub 2018 Apr 17.

PMID:
29805089
16.

The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase.

White PJ, McGarrah RW, Grimsrud PA, Tso SC, Yang WH, Haldeman JM, Grenier-Larouche T, An J, Lapworth AL, Astapova I, Hannou SA, George T, Arlotto M, Olson LB, Lai M, Zhang GF, Ilkayeva O, Herman MA, Wynn RM, Chuang DT, Newgard CB.

Cell Metab. 2018 Jun 5;27(6):1281-1293.e7. doi: 10.1016/j.cmet.2018.04.015. Epub 2018 May 17.

17.

Physiological mechanisms of sustained fumagillin-induced weight loss.

An J, Wang L, Patnode ML, Ridaura VK, Haldeman JM, Stevens RD, Ilkayeva O, Bain JR, Muehlbauer MJ, Glynn EL, Thomas S, Muoio D, Summers SA, Vath JE, Hughes TE, Gordon JI, Newgard CB.

JCI Insight. 2018 Mar 8;3(5). pii: 99453. doi: 10.1172/jci.insight.99453.

18.

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling.

Softic S, Gupta MK, Wang GX, Fujisaka S, O'Neill BT, Rao TN, Willoughby J, Harbison C, Fitzgerald K, Ilkayeva O, Newgard CB, Cohen DE, Kahn CR.

J Clin Invest. 2018 Mar 1;128(3):1199. doi: 10.1172/JCI99009. Epub 2018 Mar 1. No abstract available.

19.

Kruppel-like factor 15 is required for the cardiac adaptive response to fasting.

Sugi K, Hsieh PN, Ilkayeva O, Shelkay S, Moroney B, Baadh P, Haynes B, Pophal M, Fan L, Newgard CB, Prosdocimo DA, Jain MK.

PLoS One. 2018 Feb 6;13(2):e0192376. doi: 10.1371/journal.pone.0192376. eCollection 2018.

20.

Erratum. Maternal BMI and Glycemia Impact the Fetal Metabolome. Diabetes Care 2017;40:902-910.

Lowe WL Jr, Bain JR, Nodzenski M, Reisetter AC, Muehlbauer MJ, Stevens RD, Ilkayeva OR, Lowe LP, Metzger BE, Newgard CB, Scholtens DM; HAPO Study Cooperative Research Group.

Diabetes Care. 2018 Mar;41(3):640. doi: 10.2337/dc18-er03b. Epub 2018 Jan 8. No abstract available.

21.

Perinatal western-type diet and associated gestational weight gain alter postpartum maternal mood.

Bolton JL, Wiley MG, Ryan B, Truong S, Strait M, Baker DC, Yang NY, Ilkayeva O, O'Connell TM, Wroth SW, Sánchez CL, Swamy G, Newgard C, Kuhn C, Bilbo SD, Simmons LA.

Brain Behav. 2017 Sep 14;7(10):e00828. doi: 10.1002/brb3.828. eCollection 2017 Oct.

22.

Metabolomic analysis of insulin resistance across different mouse strains and diets.

Stöckli J, Fisher-Wellman KH, Chaudhuri R, Zeng XY, Fazakerley DJ, Meoli CC, Thomas KC, Hoffman NJ, Mangiafico SP, Xirouchaki CE, Yang CH, Ilkayeva O, Wong K, Cooney GJ, Andrikopoulos S, Muoio DM, James DE.

J Biol Chem. 2017 Nov 24;292(47):19135-19145. doi: 10.1074/jbc.M117.818351. Epub 2017 Oct 5.

23.

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling.

Softic S, Gupta MK, Wang GX, Fujisaka S, O'Neill BT, Rao TN, Willoughby J, Harbison C, Fitzgerald K, Ilkayeva O, Newgard CB, Cohen DE, Kahn CR.

J Clin Invest. 2017 Nov 1;127(11):4059-4074. doi: 10.1172/JCI94585. Epub 2017 Oct 3. Erratum in: J Clin Invest. 2018 Mar 1;128(3):1199.

24.

Plasma acylcarnitines are associated with pulmonary hypertension.

Luo N, Craig D, Ilkayeva O, Muehlbauer M, Kraus WE, Newgard CB, Shah SH, Rajagopal S.

Pulm Circ. 2017 Feb 1;7(1):211-218. doi: 10.1086/690554. eCollection 2017 Mar.

25.

Targeted Metabolomics Demonstrates Distinct and Overlapping Maternal Metabolites Associated With BMI, Glucose, and Insulin Sensitivity During Pregnancy Across Four Ancestry Groups.

Jacob S, Nodzenski M, Reisetter AC, Bain JR, Muehlbauer MJ, Stevens RD, Ilkayeva OR, Lowe LP, Metzger BE, Newgard CB, Scholtens DM, Lowe WL Jr; HAPO Study Cooperative Research Group.

Diabetes Care. 2017 Jul;40(7):911-919. doi: 10.2337/dc16-2453.

26.

Maternal BMI and Glycemia Impact the Fetal Metabolome.

Lowe WL Jr, Bain JR, Nodzenski M, Reisetter AC, Muehlbauer MJ, Stevens RD, Ilkayeva OR, Lowe LP, Metzger BE, Newgard CB, Scholtens DM; HAPO Study Cooperative Research Group.

Diabetes Care. 2017 Jul;40(7):902-910. doi: 10.2337/dc16-2452. Erratum in: Diabetes Care. 2018 Jan 8;:.

27.

N6-methyladenosine is required for the hypoxic stabilization of specific mRNAs.

Fry NJ, Law BA, Ilkayeva OR, Holley CL, Mansfield KD.

RNA. 2017 Sep;23(9):1444-1455. doi: 10.1261/rna.061044.117. Epub 2017 Jun 13.

28.

Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation.

Dean ED, Li M, Prasad N, Wisniewski SN, Von Deylen A, Spaeth J, Maddison L, Botros A, Sedgeman LR, Bozadjieva N, Ilkayeva O, Coldren A, Poffenberger G, Shostak A, Semich MC, Aamodt KI, Phillips N, Yan H, Bernal-Mizrachi E, Corbin JD, Vickers KC, Levy SE, Dai C, Newgard C, Gu W, Stein R, Chen W, Powers AC.

Cell Metab. 2017 Jun 6;25(6):1362-1373.e5. doi: 10.1016/j.cmet.2017.05.011.

29.

Sildenafil Treatment in Heart Failure With Preserved Ejection Fraction: Targeted Metabolomic Profiling in the RELAX Trial.

Wang H, Anstrom K, Ilkayeva O, Muehlbauer MJ, Bain JR, McNulty S, Newgard CB, Kraus WE, Hernandez A, Felker GM, Redfield M, Shah SH.

JAMA Cardiol. 2017 Aug 1;2(8):896-901. doi: 10.1001/jamacardio.2017.1239.

30.

SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion.

Anderson KA, Huynh FK, Fisher-Wellman K, Stuart JD, Peterson BS, Douros JD, Wagner GR, Thompson JW, Madsen AS, Green MF, Sivley RM, Ilkayeva OR, Stevens RD, Backos DS, Capra JA, Olsen CA, Campbell JE, Muoio DM, Grimsrud PA, Hirschey MD.

Cell Metab. 2017 Apr 4;25(4):838-855.e15. doi: 10.1016/j.cmet.2017.03.003.

31.

A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation.

Wagner GR, Bhatt DP, O'Connell TM, Thompson JW, Dubois LG, Backos DS, Yang H, Mitchell GA, Ilkayeva OR, Stevens RD, Grimsrud PA, Hirschey MD.

Cell Metab. 2017 Apr 4;25(4):823-837.e8. doi: 10.1016/j.cmet.2017.03.006.

32.

Metabolic Alterations Contribute to Enhanced Inflammatory Cytokine Production in Irgm1-deficient Macrophages.

Schmidt EA, Fee BE, Henry SC, Nichols AG, Shinohara ML, Rathmell JC, MacIver NJ, Coers J, Ilkayeva OR, Koves TR, Taylor GA.

J Biol Chem. 2017 Mar 17;292(11):4651-4662. doi: 10.1074/jbc.M116.770735. Epub 2017 Feb 1.

33.

Mixture model normalization for non-targeted gas chromatography/mass spectrometry metabolomics data.

Reisetter AC, Muehlbauer MJ, Bain JR, Nodzenski M, Stevens RD, Ilkayeva O, Metzger BE, Newgard CB, Lowe WL Jr, Scholtens DM.

BMC Bioinformatics. 2017 Feb 2;18(1):84. doi: 10.1186/s12859-017-1501-7.

34.

Prior Dietary Practices and Connections to a Human Gut Microbial Metacommunity Alter Responses to Diet Interventions.

Griffin NW, Ahern PP, Cheng J, Heath AC, Ilkayeva O, Newgard CB, Fontana L, Gordon JI.

Cell Host Microbe. 2017 Jan 11;21(1):84-96. doi: 10.1016/j.chom.2016.12.006. Epub 2016 Dec 29.

35.

Associations of maternal BMI and insulin resistance with the maternal metabolome and newborn outcomes.

Sandler V, Reisetter AC, Bain JR, Muehlbauer MJ, Nodzenski M, Stevens RD, Ilkayeva O, Lowe LP, Metzger BE, Newgard CB, Scholtens DM, Lowe WL Jr; HAPO Study Cooperative Research Group.

Diabetologia. 2017 Mar;60(3):518-530. doi: 10.1007/s00125-016-4182-2. Epub 2016 Dec 16.

36.

Effects of a gut pathobiont in a gnotobiotic mouse model of childhood undernutrition.

Wagner VE, Dey N, Guruge J, Hsiao A, Ahern PP, Semenkovich NP, Blanton LV, Cheng J, Griffin N, Stappenbeck TS, Ilkayeva O, Newgard CB, Petri W, Haque R, Ahmed T, Gordon JI.

Sci Transl Med. 2016 Nov 23;8(366):366ra164.

37.

HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism.

Bradley T, Yang G, Ilkayeva O, Holl TM, Zhang R, Zhang J, Santra S, Fox CB, Reed SG, Parks R, Bowman CM, Bouton-Verville H, Sutherland LL, Scearce RM, Vandergrift N, Kepler TB, Moody MA, Liao HX, Alam SM, McLendon R, Everitt JI, Newgard CB, Verkoczy L, Kelsoe G, Haynes BF.

J Immunol. 2016 Dec 15;197(12):4663-4673. Epub 2016 Nov 14.

38.

Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation.

McDonnell E, Crown SB, Fox DB, Kitir B, Ilkayeva OR, Olsen CA, Grimsrud PA, Hirschey MD.

Cell Rep. 2016 Nov 1;17(6):1463-1472. doi: 10.1016/j.celrep.2016.10.012.

39.

Arsenite Uncouples Mitochondrial Respiration and Induces a Warburg-Like Effect in Caenorhabditis elegans.

Luz AT, Godebo TR, Bhatt DP, Ilkayeva OR, Maurer LL, Hirschey MD, Meyer JN.

Toxicol Sci. 2016 Nov;154(1):195. No abstract available.

40.

N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection.

Gokhale NS, McIntyre ABR, McFadden MJ, Roder AE, Kennedy EM, Gandara JA, Hopcraft SE, Quicke KM, Vazquez C, Willer J, Ilkayeva OR, Law BA, Holley CL, Garcia-Blanco MA, Evans MJ, Suthar MS, Bradrick SS, Mason CE, Horner SM.

Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.

41.

Enhanced GLUT4-Dependent Glucose Transport Relieves Nutrient Stress in Obese Mice Through Changes in Lipid and Amino Acid Metabolism.

Gurley JM, Ilkayeva O, Jackson RM, Griesel BA, White P, Matsuzaki S, Qaisar R, Van Remmen H, Humphries KM, Newgard CB, Olson AL.

Diabetes. 2016 Dec;65(12):3585-3597. Epub 2016 Sep 27.

42.

Metabolomic Profiling Identifies Novel Circulating Biomarkers of Mitochondrial Dysfunction Differentially Elevated in Heart Failure With Preserved Versus Reduced Ejection Fraction: Evidence for Shared Metabolic Impairments in Clinical Heart Failure.

Hunter WG, Kelly JP, McGarrah RW 3rd, Khouri MG, Craig D, Haynes C, Ilkayeva O, Stevens RD, Bain JR, Muehlbauer MJ, Newgard CB, Felker GM, Hernandez AF, Velazquez EJ, Kraus WE, Shah SH.

J Am Heart Assoc. 2016 Jul 29;5(8). pii: e003190. doi: 10.1161/JAHA.115.003190.

43.

Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export.

White PJ, Lapworth AL, An J, Wang L, McGarrah RW, Stevens RD, Ilkayeva O, George T, Muehlbauer MJ, Bain JR, Trimmer JK, Brosnan MJ, Rolph TP, Newgard CB.

Mol Metab. 2016 Apr 22;5(7):538-551. doi: 10.1016/j.molmet.2016.04.006. eCollection 2016 Jul.

44.

Hepatic mTORC1 Opposes Impaired Insulin Action to Control Mitochondrial Metabolism in Obesity.

Kucejova B, Duarte J, Satapati S, Fu X, Ilkayeva O, Newgard CB, Brugarolas J, Burgess SC.

Cell Rep. 2016 Jul 12;16(2):508-519. doi: 10.1016/j.celrep.2016.06.006. Epub 2016 Jun 23.

45.

From the Cover: Arsenite Uncouples Mitochondrial Respiration and Induces a Warburg-like Effect in Caenorhabditis elegans.

Luz AL, Godebo TR, Bhatt DP, Ilkayeva OR, Maurer LL, Hirschey MD, Meyer JN.

Toxicol Sci. 2016 Aug;152(2):349-62. doi: 10.1093/toxsci/kfw093. Epub 2016 May 20. Erratum in: Toxicol Sci. 2016 Nov;154(1):195.

46.

Metabolic Networks and Metabolites Underlie Associations Between Maternal Glucose During Pregnancy and Newborn Size at Birth.

Scholtens DM, Bain JR, Reisetter AC, Muehlbauer MJ, Nodzenski M, Stevens RD, Ilkayeva O, Lowe LP, Metzger BE, Newgard CB, Lowe WL Jr; HAPO Study Cooperative Research Group.

Diabetes. 2016 Jul;65(7):2039-50. doi: 10.2337/db15-1748. Epub 2016 Apr 5.

47.

Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure.

Sun H, Olson KC, Gao C, Prosdocimo DA, Zhou M, Wang Z, Jeyaraj D, Youn JY, Ren S, Liu Y, Rau CD, Shah S, Ilkayeva O, Gui WJ, William NS, Wynn RM, Newgard CB, Cai H, Xiao X, Chuang DT, Schulze PC, Lynch C, Jain MK, Wang Y.

Circulation. 2016 May 24;133(21):2038-49. doi: 10.1161/CIRCULATIONAHA.115.020226. Epub 2016 Apr 8.

48.

Integrated Regulation of Hepatic Lipid and Glucose Metabolism by Adipose Triacylglycerol Lipase and FoxO Proteins.

Zhang W, Bu SY, Mashek MT, O-Sullivan I, Sibai Z, Khan SA, Ilkayeva O, Newgard CB, Mashek DG, Unterman TG.

Cell Rep. 2016 Apr 12;15(2):349-59. doi: 10.1016/j.celrep.2016.03.021. Epub 2016 Mar 31.

49.

Research Resource: Roles for Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) in Systems Metabolism.

Marcelo KL, Ribar T, Means CR, Tsimelzon A, Stevens RD, Ilkayeva O, Bain JR, Hilsenbeck SG, Newgard CB, Means AR, York B.

Mol Endocrinol. 2016 May;30(5):557-72. doi: 10.1210/me.2016-1021. Epub 2016 Mar 22.

50.

Sialylated Milk Oligosaccharides Promote Microbiota-Dependent Growth in Models of Infant Undernutrition.

Charbonneau MR, O'Donnell D, Blanton LV, Totten SM, Davis JC, Barratt MJ, Cheng J, Guruge J, Talcott M, Bain JR, Muehlbauer MJ, Ilkayeva O, Wu C, Struckmeyer T, Barile D, Mangani C, Jorgensen J, Fan YM, Maleta K, Dewey KG, Ashorn P, Newgard CB, Lebrilla C, Mills DA, Gordon JI.

Cell. 2016 Feb 25;164(5):859-71. doi: 10.1016/j.cell.2016.01.024. Epub 2016 Feb 18.

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