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Items: 1 to 50 of 94

1.

Secretome profile selection of optimal IVF embryos by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.

Iles RK, Sharara FI, Zmuidinaite R, Abdo G, Keshavarz S, Butler SA.

J Assist Reprod Genet. 2019 Jun;36(6):1153-1160. doi: 10.1007/s10815-019-01444-7. Epub 2019 May 15.

2.

Response to the letter "Sleep characteristics of children with Williams syndrome in relation to saliva melatonin and cortisol".

Sniecinska-Cooper AM, Iles RK, Butler SA, Jones H, Bayford R, Dimitriou D.

Sleep Med. 2015 Sep;16(9):1177. doi: 10.1016/j.sleep.2015.05.005. Epub 2015 May 21. No abstract available.

PMID:
26141005
3.

Direct and rapid mass spectral fingerprinting of maternal urine for the detection of Down syndrome pregnancy.

Iles RK, Shahpari ME, Cuckle H, Butler SA.

Clin Proteomics. 2015 Mar 24;12(1):9. doi: 10.1186/s12014-015-9082-9. eCollection 2015.

4.
5.

Determination of urinary cortisol, cortisone and 6-sulfatoxymelatonin using dilute and shoot ultra-high pressure liquid chromatography-tandem mass spectrometry.

Sniecinska-Cooper AM, Shah AJ, Dimitriou D, Iles RK, Butler SA, Bayford R.

J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Jan 26;978-979:18-23. doi: 10.1016/j.jchromb.2014.11.016. Epub 2014 Dec 3.

PMID:
25531866
6.

Abnormal secretion of melatonin and cortisol in relation to sleep disturbances in children with Williams syndrome.

Sniecinska-Cooper AM, Iles RK, Butler SA, Jones H, Bayford R, Dimitriou D.

Sleep Med. 2015 Jan;16(1):94-100. doi: 10.1016/j.sleep.2014.09.003. Epub 2014 Sep 19.

PMID:
25441742
7.
8.

HILIC-MS-based shotgun metabolomic profiling of maternal urine at 9-23 weeks of gestation - establishing the baseline changes in the maternal metabolome.

Trivedi DK, Iles RK.

Biomed Chromatogr. 2015 Feb;29(2):240-5. doi: 10.1002/bmc.3266. Epub 2014 Jun 5.

PMID:
24898723
9.

Do not just do it, do it right: urinary metabolomics--establishing clinically relevant baselines.

Trivedi DK, Iles RK.

Biomed Chromatogr. 2014 Nov;28(11):1491-501. doi: 10.1002/bmc.3219. Epub 2014 May 2. Review.

PMID:
24788800
10.

Novel insights into the expression of CGB1 & 2 genes by epithelial cancer cell lines secreting ectopic free hCGβ.

Burczynska BB, Kobrouly L, Butler SA, Naase M, Iles RK.

Anticancer Res. 2014 May;34(5):2239-48.

PMID:
24778026
11.

Stable knockdown of hCGβ mRNA expression in bladder cancer cells results in significant growth inhibition.

Burczynska B, Booth MJ, Iles RK, Shah A, Shiled A, Butler SA.

Anticancer Res. 2013 Sep;33(9):3611-4.

PMID:
24023286
12.

Single point biochemical measurement algorithm for early diagnosis of ectopic pregnancy.

Butler SA, Abban TK, Borrelli PT, Luttoo JM, Kemp B, Iles RK.

Clin Biochem. 2013 Sep;46(13-14):1257-63. doi: 10.1016/j.clinbiochem.2013.06.019. Epub 2013 Jul 3.

PMID:
23830901
13.

Human chorionic gonadotropin (hCG) in the secretome of cultured embryos: hyperglycosylated hCG and hCG-free beta subunit are potential markers for infertility management and treatment.

Butler SA, Luttoo J, Freire MO, Abban TK, Borrelli PT, Iles RK.

Reprod Sci. 2013 Sep;20(9):1038-45. doi: 10.1177/1933719112472739. Epub 2013 Feb 25.

PMID:
23439616
14.

Differential proteolysis of insulin-like growth factor binding protein-1 (IGFBP-1) in pregnancy.

Hills FA, Iles RK, Sullivan MH.

J Perinat Med. 2013 May;41(3):241-9. doi: 10.1515/jpm-2012-0086.

PMID:
23183724
15.

Arsenic trioxide induces cervical cancer apoptosis, but specifically targets human papillomavirus-infected cell populations.

Wen X, Li D, Zhang Y, Liu S, Ghali L, Iles RK.

Anticancer Drugs. 2012 Mar;23(3):280-7. doi: 10.1097/CAD.0b013e32834f1fd3.

PMID:
22245994
16.

Estradiol, progesterone, testosterone profiles in human follicular fluid and cultured granulosa cells from luteinized pre-ovulatory follicles.

Wen X, Li D, Tozer AJ, Docherty SM, Iles RK.

Reprod Biol Endocrinol. 2010 Oct 11;8:117. doi: 10.1186/1477-7827-8-117.

17.

Gonadotropins and gonadotropin receptors--evolutional genetics, signalling mechanisms, extra gonadal function and roles in oncogenesis.

Iles RK, Butler SA.

Mol Cell Endocrinol. 2010 Nov 25;329(1-2):1-2. doi: 10.1016/j.mce.2010.07.024. Epub 2010 Jul 30. No abstract available.

PMID:
20674664
18.

Does hCG or hCGβ play a role in cancer cell biology?

Iles RK, Delves PJ, Butler SA.

Mol Cell Endocrinol. 2010 Nov 25;329(1-2):62-70. doi: 10.1016/j.mce.2010.07.014. Epub 2010 Jul 21.

PMID:
20654692
19.

Purine metabolite levels in preovulatory human follicles may hold the key to ovarian hyperstimulation syndrome.

Iles RK, Docherty SM.

Metabolism. 2010 Oct;59(10):e10-1. doi: 10.1016/j.metabol.2010.04.005. Epub 2010 May 24. No abstract available.

PMID:
20494380
20.

Bony metastases from breast cancer - a study of foetal antigen 2 as a blood tumour marker.

Cheung KL, Iles RK, Robertson JF.

World J Surg Oncol. 2010 May 13;8:38. doi: 10.1186/1477-7819-8-38.

21.

High follicular fluid adenosine levels may be pivotal in the metabolism and recycling of adenosine nucleotides in the human follicle.

Wen X, Perrett D, Jones N, Tozer AJ, Docherty SM, Iles RK.

Metabolism. 2010 Aug;59(8):1145-55. doi: 10.1016/j.metabol.2009.09.037. Epub 2010 Jan 4.

PMID:
20045541
22.

Capillary electrophoresis of human follicular fluid.

Wen X, Perrett D, Patel P, Li N, Docherty SM, Tozer AJ, Iles RK.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Dec 1;877(31):3946-52. doi: 10.1016/j.jchromb.2009.09.046. Epub 2009 Oct 22.

PMID:
19889587
23.

Clinical and endocrinological changes after electro-acupuncture treatment in patients with osteoarthritis of the knee.

Ahsin S, Saleem S, Bhatti AM, Iles RK, Aslam M.

Pain. 2009 Dec 15;147(1-3):60-6. doi: 10.1016/j.pain.2009.08.004. Epub 2009 Sep 18.

PMID:
19766392
24.

hCG beta expression by cervical squamous carcinoma--in vivo histological association with tumour invasion and apoptosis.

Li D, Wen X, Ghali L, Al-Shalabi FM, Docherty SM, Purkis P, Iles RK.

Histopathology. 2008 Aug;53(2):147-55. doi: 10.1111/j.1365-2559.2008.03082.x.

PMID:
18752498
25.

Towards the development of an electrochemical biosensor for hCGbeta detection.

Kassanos P, Iles RK, Bayford RH, Demosthenous A.

Physiol Meas. 2008 Jun;29(6):S241-54. doi: 10.1088/0967-3334/29/6/S21. Epub 2008 Jun 10.

PMID:
18544815
26.

Human granulosa-lutein cell in vitro production of progesterone, inhibin A, inhibin B, and activin A are dependent on follicular size and not the presence of the oocyte.

Wen X, Tozer AJ, Li D, Docherty SM, Al-Shawaf T, Iles RK.

Fertil Steril. 2008 May;89(5 Suppl):1406-13. Epub 2007 Aug 6.

PMID:
17681301
27.

An introduction to mass spectrometry based proteomics-detection and characterization of gonadotropins and related molecules.

Kicman AT, Parkin MC, Iles RK.

Mol Cell Endocrinol. 2007 Jan 2;260-262:212-27. Epub 2006 Nov 13. Review.

PMID:
17097803
28.

Ectopic hCGbeta expression by epithelial cancer: malignant behaviour, metastasis and inhibition of tumor cell apoptosis.

Iles RK.

Mol Cell Endocrinol. 2007 Jan 2;260-262:264-70. Epub 2006 Oct 27. Review.

PMID:
17069968
29.

Designing a new generation of anti-hCG vaccines for cancer therapy.

Delves PJ, Iles RK, Roitt IM, Lund T.

Mol Cell Endocrinol. 2007 Jan 2;260-262:276-81. Epub 2006 Oct 17.

PMID:
17049720
30.

Detection of human chorionic gonadotrophin-beta in serum or urine of prostate cancer patients is of no clinical significance.

Otite U, Baithun S, Chinegwundoh F, Nargund VH, Iles RK.

Tumour Biol. 2006;27(4):181-6. Epub 2006 Apr 27.

PMID:
16651852
31.

Follicular fluid levels of inhibin A, inhibin B, and activin A levels reflect changes in follicle size but are not independent markers of the oocyte's ability to fertilize.

Wen X, Tozer AJ, Butler SA, Bell CM, Docherty SM, Iles RK.

Fertil Steril. 2006 Jun;85(6):1723-9. Epub 2006 May 2.

PMID:
16650414
34.

Characteristics of populations of granulosa cells from individual follicles in women undergoing 'coasting' during controlled ovarian stimulation (COS) for IVF.

Tozer AJ, Iles RK, Iammarrone E, Nica RA, Gillott CM, Xusong W, Al-Shawaf T, Grudzinskas JG.

Hum Reprod. 2004 Nov;19(11):2561-8. Epub 2004 Oct 7.

PMID:
15471924
36.

The effects of 'coasting' on follicular fluid concentrations of vascular endothelial growth factor in women at risk of developing ovarian hyperstimulation syndrome.

Tozer AJ, Iles RK, Iammarrone E, Gillott CM, Al-Shawaf T, Grudzinskas JG.

Hum Reprod. 2004 Mar;19(3):522-8. Epub 2004 Jan 29.

PMID:
14998945
37.

Reduction of bladder cancer cell growth in response to hCGbeta CTP37 vaccinated mouse serum.

Butler SA, Staite EM, Iles RK.

Oncol Res. 2003;14(2):93-100.

PMID:
14649543
38.

Human chorionic gonadotropin isoforms in the diagnosis of ectopic pregnancy.

Borrelli PT, Butler SA, Docherty SM, Staite EM, Borrelli AL, Iles RK.

Clin Chem. 2003 Dec;49(12):2045-9.

41.

Enhanced affinity capture MALDI-TOF MS: orientation of an immunoglobulin G using recombinant protein G.

Neubert H, Jacoby ES, Bansal SS, Iles RK, Cowan DA, Kicman AT.

Anal Chem. 2002 Aug 1;74(15):3677-83.

PMID:
12175153
42.

High concentrations of CA 125 in uterine flushings: influence of cause of infertility and menstrual cycle day.

Hamilton JA, Iles RK, Gunn LK, Wilson CM, Lower AM, Grudzinskas JG.

Gynecol Endocrinol. 2002 Feb;16(1):19-25.

PMID:
11915577
43.

The analysis of human amniotic fluid using capillary electrophoresis.

Stewart CJ, Iles RK, Perrett D.

Electrophoresis. 2001 Apr;22(6):1136-42.

PMID:
11358139
44.

Regulation of endometrial cancer cell growth by luteinizing hormone (LH) and follicle stimulating hormone (FSH).

Davies S, Bax CM, Chatzaki E, Chard T, Iles RK.

Br J Cancer. 2000 Dec;83(12):1730-4.

47.

Interference of Luteinizing Hormone beta-Core Fragment in Urinary Gonadotropin Assays.

O'Connor JF, Kovalevskaya G, Birken S, Iles RK.

Clin Chem. 1999 Dec;45(12):2290-2292. No abstract available.

PMID:
10585374
48.

Dimerization of urinary beta-core/hCFbetacf: a cause of poor beta-core assay performance in Down syndrome screening studies.

Iles RK, Butler SA, Jacoby E.

Prenat Diagn. 1999 Aug;19(8):790-2. No abstract available.

PMID:
10451534
49.

The beta-subunit of human chorionic gonadotrophin exists as a homodimer.

Butler SA, Laidler P, Porter JR, Kicman AT, Chard T, Cowan DA, Iles RK.

J Mol Endocrinol. 1999 Apr;22(2):185-92.

PMID:
10194521

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