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Items: 1 to 50 of 228

1.

Quantitative gait, cognitive decline, and incident dementia: The Rotterdam Study.

Darweesh SKL, Licher S, Wolters FJ, Koudstaal PJ, Ikram MK, Ikram MA.

Alzheimers Dement. 2019 Sep 9. pii: S1552-5260(19)30088-3. doi: 10.1016/j.jalz.2019.03.013. [Epub ahead of print]

PMID:
31515066
2.

Genetic predisposition, modifiable-risk-factor profile and long-term dementia risk in the general population.

Licher S, Ahmad S, Karamujić-Čomić H, Voortman T, Leening MJG, Ikram MA, Ikram MK.

Nat Med. 2019 Sep;25(9):1364-1369. doi: 10.1038/s41591-019-0547-7. Epub 2019 Aug 26.

PMID:
31451782
3.

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes.

van der Lee SJ, Knol MJ, Chauhan G, Satizabal CL, Smith AV, Hofer E, Bis JC, Hibar DP, Hilal S, van den Akker EB, Arfanakis K, Bernard M, Yanek LR, Amin N, Crivello F, Cheung JW, Harris TB, Saba Y, Lopez OL, Li S, van der Grond J, Yu L, Paus T, Roshchupkin GV, Amouyel P, Jahanshad N, Taylor KD, Yang Q, Mathias RA, Boehringer S, Mazoyer B, Rice K, Cheng CY, Maillard P, van Heemst D, Wong TY, Niessen WJ, Beiser AS, Beekman M, Zhao W, Nyquist PA, Chen C, Launer LJ, Psaty BM, Ikram MK, Vernooij MW, Schmidt H, Pausova Z, Becker DM, De Jager PL, Thompson PM, van Duijn CM, Bennett DA, Slagboom PE, Schmidt R, Longstreth WT, Ikram MA, Seshadri S, Debette S, Gudnason V, Adams HHH, DeCarli C.

Commun Biol. 2019 Aug 2;2:285. doi: 10.1038/s42003-019-0537-9. eCollection 2019.

4.

Prevalence and clinical relevance of diffusion-weighted imaging lesions: The Rotterdam study.

Hilal S, Baaij LGA, de Groot M, Niessen WJ, Ikram MK, Ikram MA, Vernooij MW.

Neurology. 2019 Sep 10;93(11):e1058-e1067. doi: 10.1212/WNL.0000000000008090. Epub 2019 Aug 7.

PMID:
31391244
5.

Vitamin D Status and Risk of Stroke.

Berghout BP, Fani L, Heshmatollah A, Koudstaal PJ, Ikram MA, Zillikens MC, Ikram MK.

Stroke. 2019 Sep;50(9):2293-2298. doi: 10.1161/STROKEAHA.119.025449. Epub 2019 Aug 8.

PMID:
31390971
6.

Prevalence and Risk Factors for Cognitive Impairment and Dementia in Indians: A Multiethnic Perspective from a Singaporean Study.

Wong MYZ, Tan CS, Venketasubramanian N, Chen C, Ikram MK, Cheng CY, Hilal S.

J Alzheimers Dis. 2019;71(1):341-351. doi: 10.3233/JAD-190610.

PMID:
31381520
7.

Hemoglobin and anemia in relation to dementia risk and accompanying changes on brain MRI.

Wolters FJ, Zonneveld HI, Licher S, Cremers LGM; Heart Brain Connection Collaborative Research Group, Ikram MK, Koudstaal PJ, Vernooij MW, Ikram MA.

Neurology. 2019 Aug 27;93(9):e917-e926. doi: 10.1212/WNL.0000000000008003. Epub 2019 Jul 31.

PMID:
31366722
8.

Vertebrobasilar artery calcification: Prevalence and risk factors in the general population.

van der Toorn JE, Engelkes SR, Ikram MK, Ikram MA, Vernooij MW, Kavousi M, Bos D.

Atherosclerosis. 2019 Jul;286:46-52. doi: 10.1016/j.atherosclerosis.2019.05.001. Epub 2019 May 4.

9.

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C, Hofer E, Ikram MA, Karlsson R, Knowles E, Lahti J, Leber M, Li S, Mather KA, Melle I, Morris D, Oldmeadow C, Palviainen T, Payton A, Pazoki R, Petrovic K, Reynolds CA, Sargurupremraj M, Scholz M, Smith JA, Smith AV, Terzikhan N, Thalamuthu A, Trompet S, van der Lee SJ, Ware EB, Windham BG, Wright MJ, Yang J, Yu J, Ames D, Amin N, Amouyel P, Andreassen OA, Armstrong NJ, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, Böhmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, Dehghan A, Dick D, Dickinson D, Eriksson JG, Evangelou E, Faul JD, Ford I, Freimer NA, Gao H, Giegling I, Gillespie NA, Gordon SD, Gottesman RF, Griswold ME, Gudnason V, Harris TB, Hartmann AM, Hatzimanolis A, Heiss G, Holliday EG, Joshi PK, Kähönen M, Kardia SLR, Karlsson I, Kleineidam L, Knopman DS, Kochan NA, Konte B, Kwok JB, Le Hellard S, Lee T, Lehtimäki T, Li SC, Lill CM, Liu T, Koini M, London E, Longstreth WT Jr, Lopez OL, Loukola A, Luck T, Lundervold AJ, Lundquist A, Lyytikäinen LP, Martin NG, Montgomery GW, Murray AD, Need AC, Noordam R, Nyberg L, Ollier W, Papenberg G, Pattie A, Polasek O, Poldrack RA, Psaty BM, Reppermund S, Riedel-Heller SG, Rose RJ, Rotter JI, Roussos P, Rovio SP, Saba Y, Sabb FW, Sachdev PS, Satizabal CL, Schmid M, Scott RJ, Scult MA, Simino J, Slagboom PE, Smyrnis N, Soumaré A, Stefanis NC, Stott DJ, Straub RE, Sundet K, Taylor AM, Taylor KD, Tzoulaki I, Tzourio C, Uitterlinden A, Vitart V, Voineskos AN, Kaprio J, Wagner M, Wagner H, Weinhold L, Wen KH, Widen E, Yang Q, Zhao W, Adams HHH, Arking DE, Bilder RM, Bitsios P, Boerwinkle E, Chiba-Falek O, Corvin A, De Jager PL, Debette S, Donohoe G, Elliott P, Fitzpatrick AL, Gill M, Glahn DC, Hägg S, Hansell NK, Hariri AR, Ikram MK, Jukema JW, Vuoksimaa E, Keller MC, Kremen WS, Launer L, Lindenberger U, Palotie A, Pedersen NL, Pendleton N, Porteous DJ, Räikkönen K, Raitakari OT, Ramirez A, Reinvang I, Rudan I, Dan Rujescu, Schmidt R, Schmidt H, Schofield PW, Schofield PR, Starr JM, Steen VM, Trollor JN, Turner ST, Van Duijn CM, Villringer A, Weinberger DR, Weir DR, Wilson JF, Malhotra A, McIntosh AM, Gale CR, Seshadri S, Mosley TH Jr, Bressler J, Lencz T, Deary IJ.

Nat Commun. 2019 May 1;10(1):2068. doi: 10.1038/s41467-019-10160-w.

10.

Sleep and risk of parkinsonism and Parkinson's disease: a population-based study.

Lysen TS, Darweesh SKL, Ikram MK, Luik AI, Ikram MA.

Brain. 2019 Jul 1;142(7):2013-2022. doi: 10.1093/brain/awz113.

PMID:
31038176
11.

Balance between innate versus adaptive immune system and the risk of dementia: a population-based cohort study.

van der Willik KD, Fani L, Rizopoulos D, Licher S, Fest J, Schagen SB, Ikram MK, Ikram MA.

J Neuroinflammation. 2019 Mar 30;16(1):68. doi: 10.1186/s12974-019-1454-z.

12.

Global Brain Perfusion and the Risk of Transient Ischemic Attack and Ischemic Stroke: The Rotterdam Study.

Fani L, Bos D, Mutlu U, Portegies MLP, Zonneveld HI, Koudstaal PJ, Vernooij MW, Ikram MA, Ikram MK.

J Am Heart Assoc. 2019 Apr 2;8(7):e011565. doi: 10.1161/JAHA.118.011565.

13.

Genetic variation underlying cognition and its relation with neurological outcomes and brain imaging.

Knol MJ, Heshmatollah A, Cremers LGM, Ikram MK, Uitterlinden AG, van Duijn CM, Niessen WJ, Vernooij MW, Ikram MA, Adams HHH.

Aging (Albany NY). 2019 Mar 4;11(5):1440-1456. doi: 10.18632/aging.101844.

14.

Alzheimer's disease as a multistage process: an analysis from a population-based cohort study.

Licher S, van der Willik KD, Vinke EJ, Yilmaz P, Fani L, Schagen SB, Ikram MA, Ikram MK.

Aging (Albany NY). 2019 Feb 27;11(4):1163-1176. doi: 10.18632/aging.101816.

15.

Placental Growth Factor as an Indicator of Maternal Cardiovascular Risk After Pregnancy.

Benschop L, Schalekamp-Timmermans S, Broere-Brown ZA, Roeters van Lennep JE, Jaddoe VWV, Roos-Hesselink JW, Ikram MK, Steegers EAP, Roberts JM, Gandley RE.

Circulation. 2019 Apr 2;139(14):1698-1709. doi: 10.1161/CIRCULATIONAHA.118.036632.

PMID:
30760000
16.

Lifetime risk and multimorbidity of non-communicable diseases and disease-free life expectancy in the general population: A population-based cohort study.

Licher S, Heshmatollah A, van der Willik KD, Stricker BHC, Ruiter R, de Roos EW, Lahousse L, Koudstaal PJ, Hofman A, Fani L, Brusselle GGO, Bos D, Arshi B, Kavousi M, Leening MJG, Ikram MK, Ikram MA.

PLoS Med. 2019 Feb 4;16(2):e1002741. doi: 10.1371/journal.pmed.1002741. eCollection 2019 Feb.

17.

Reader response: Sauna bathing reduces the risk of stroke in Finnish men and women: A prospective cohort study.

Dippel DW, Fransen PS, Ikram MK.

Neurology. 2019 Jan 22;92(4):205. doi: 10.1212/WNL.0000000000006808. No abstract available.

PMID:
30665915
18.

Kidney Function and the Risk of Stroke and Dementia: The Rotterdam Study.

Koop-Nieuwelink C, Sedaghat S, Mutlu U, Licher S, Franco OH, Ikram MA, Geerlings MI, Ikram MK, Bos D.

J Alzheimers Dis. 2019;67(3):821-826. doi: 10.3233/JAD-181086.

PMID:
30664508
19.

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.

Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guðnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Muñoz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT Jr, Debette S; Stroke Genetics Network (SiGN), the International Stroke Genetics Consortium (ISGC), METASTROKE, Alzheimer's Disease Genetics Consortium (ADGC), and the Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium.

Neurology. 2019 Jan 16. pii: 10.1212/WNL.0000000000006851. doi: 10.1212/WNL.0000000000006851. [Epub ahead of print]

20.

A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.

de Vries PS, Sabater-Lleal M, Huffman JE, Marten J, Song C, Pankratz N, Bartz TM, de Haan HG, Delgado GE, Eicher JD, Martinez-Perez A, Ward-Caviness CK, Brody JA, Chen MH, de Maat MPM, Frånberg M, Gill D, Kleber ME, Rivadeneira F, Soria JM, Tang W, Tofler GH, Uitterlinden AG, van Hylckama Vlieg A, Seshadri S, Boerwinkle E, Davies NM, Giese AK, Ikram MK, Kittner SJ, McKnight B, Psaty BM, Reiner AP, Sargurupremraj M, Taylor KD; INVENT Consortium; MEGASTROKE Consortium of the International Stroke Genetics Consortium, Fornage M, Hamsten A, März W, Rosendaal FR, Souto JC, Dehghan A, Johnson AD, Morrison AC, O'Donnell CJ, Smith NL.

Blood. 2019 Feb 28;133(9):967-977. doi: 10.1182/blood-2018-05-849240. Epub 2019 Jan 14.

PMID:
30642921
21.

Alterations in Brain Network Topology and Structural-Functional Connectome Coupling Relate to Cognitive Impairment.

Wang J, Khosrowabadi R, Ng KK, Hong Z, Chong JSX, Wang Y, Chen CY, Hilal S, Venketasubramanian N, Wong TY, Chen CL, Ikram MK, Zhou J.

Front Aging Neurosci. 2018 Dec 13;10:404. doi: 10.3389/fnagi.2018.00404. eCollection 2018.

22.

Practical Small Vessel Disease Score Relates to Stroke, Dementia, and Death.

Yilmaz P, Ikram MK, Niessen WJ, Ikram MA, Vernooij MW.

Stroke. 2018 Dec;49(12):2857-2865. doi: 10.1161/STROKEAHA.118.022485.

PMID:
30571403
23.

Development and Validation of a Dementia Risk Prediction Model in the General Population: An Analysis of Three Longitudinal Studies.

Licher S, Leening MJG, Yilmaz P, Wolters FJ, Heeringa J, Bindels PJE; Alzheimer’s Disease Neuroimaging Initiative, Vernooij MW, Stephan BCM, Steyerberg EW, Ikram MK, Ikram MA.

Am J Psychiatry. 2019 Jul 1;176(7):543-551. doi: 10.1176/appi.ajp.2018.18050566. Epub 2018 Dec 11.

PMID:
30525906
24.

Clinical interpretation of negative mediated interaction.

Mutlu U, Ikram MA, Ikram MK.

Int J Epidemiol. 2018 Dec 1. doi: 10.1093/ije/dyy252. [Epub ahead of print]

PMID:
30508110
25.

Cardiovascular Risk Factors Track From Mother to Child.

Benschop L, Schalekamp-Timmermans S, Roeters van Lennep JE, Jaddoe VWV, Steegers EAP, Ikram MK.

J Am Heart Assoc. 2018 Oct 2;7(19):e009536. doi: 10.1161/JAHA.118.009536.

26.

Lifetime risk of common neurological diseases in the elderly population.

Licher S, Darweesh SKL, Wolters FJ, Fani L, Heshmatollah A, Mutlu U, Koudstaal PJ, Heeringa J, Leening MJG, Ikram MK, Ikram MA.

J Neurol Neurosurg Psychiatry. 2019 Feb;90(2):148-156. doi: 10.1136/jnnp-2018-318650. Epub 2018 Oct 2.

PMID:
30279211
27.

The mediating role of the venules between smoking and ischemic stroke.

Mutlu U, Swanson SA, Klaver CCW, Hofman A, Koudstaal PJ, Ikram MA, Ikram MK.

Eur J Epidemiol. 2018 Dec;33(12):1219-1228. doi: 10.1007/s10654-018-0436-2. Epub 2018 Sep 4.

28.

Spectral-Domain OCT Measurements in Alzheimer's Disease: A Systematic Review and Meta-analysis.

Chan VTT, Sun Z, Tang S, Chen LJ, Wong A, Tham CC, Wong TY, Chen C, Ikram MK, Whitson HE, Lad EM, Mok VCT, Cheung CY.

Ophthalmology. 2019 Apr;126(4):497-510. doi: 10.1016/j.ophtha.2018.08.009. Epub 2018 Aug 13. Review.

PMID:
30114417
29.

Enlarged perivascular spaces and cognition: A meta-analysis of 5 population-based studies.

Hilal S, Tan CS, Adams HHH, Habes M, Mok V, Venketasubramanian N, Hofer E, Ikram MK, Abrigo J, Vernooij MW, Chen C, Hosten N, Volzke H, Grabe HJ, Schmidt R, Ikram MA.

Neurology. 2018 Aug 28;91(9):e832-e842. doi: 10.1212/WNL.0000000000006079. Epub 2018 Aug 1. Review.

30.

Professional occupation and the risk of Parkinson's disease.

Darweesh SKL, Ikram MK, Faber MJ, de Vries NM, Haaxma CA, Hofman A, Koudstaal PJ, Bloem BR, Ikram MA.

Eur J Neurol. 2018 Dec;25(12):1470-1476. doi: 10.1111/ene.13752. Epub 2018 Aug 6.

31.

Plasma amyloid-β levels, cerebral atrophy and risk of dementia: a population-based study.

Hilal S, Wolters FJ, Verbeek MM, Vanderstichele H, Ikram MK, Stoops E, Ikram MA, Vernooij MW.

Alzheimers Res Ther. 2018 Jun 30;10(1):63. doi: 10.1186/s13195-018-0395-6.

32.

Association of Retinal Neurodegeneration on Optical Coherence Tomography With Dementia: A Population-Based Study.

Mutlu U, Colijn JM, Ikram MA, Bonnemaijer PWM, Licher S, Wolters FJ, Tiemeier H, Koudstaal PJ, Klaver CCW, Ikram MK.

JAMA Neurol. 2018 Oct 1;75(10):1256-1263. doi: 10.1001/jamaneurol.2018.1563.

33.

Helicobacter pylori and the risk of dementia: A population-based study.

Fani L, Wolters FJ, Ikram MK, Bruno MJ, Hofman A, Koudstaal PJ, Darwish Murad S, Ikram MA.

Alzheimers Dement. 2018 Oct;14(10):1377-1382. doi: 10.1016/j.jalz.2018.05.005. Epub 2018 Jun 21.

PMID:
29935141
34.

Thinner retinal layers are associated with changes in the visual pathway: A population-based study.

Mutlu U, Ikram MK, Roshchupkin GV, Bonnemaijer PWM, Colijn JM, Vingerling JR, Niessen WJ, Ikram MA, Klaver CCW, Vernooij MW.

Hum Brain Mapp. 2018 Nov;39(11):4290-4301. doi: 10.1002/hbm.24246. Epub 2018 Jun 23.

PMID:
29935103
35.

Medication compliance in Singaporean patients with Alzheimer's disease.

Lum ZK, Suministrado MSP, Venketasubramanian N, Ikram MK, Chen C.

Singapore Med J. 2019 Mar;60(3):154-160. doi: 10.11622/smedj.2018076. Epub 2018 Jun 22.

36.

Subjective Sleep Quality is not Associated with Incident Dementia: The Rotterdam Study.

Lysen TS, Wolters FJ, Luik AI, Ikram MK, Tiemeier H, Ikram MA.

J Alzheimers Dis. 2018;64(1):239-247. doi: 10.3233/JAD-180055.

PMID:
29865066
37.

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C, Hofer E, Ikram MA, Karlsson R, Knowles E, Lahti J, Leber M, Li S, Mather KA, Melle I, Morris D, Oldmeadow C, Palviainen T, Payton A, Pazoki R, Petrovic K, Reynolds CA, Sargurupremraj M, Scholz M, Smith JA, Smith AV, Terzikhan N, Thalamuthu A, Trompet S, van der Lee SJ, Ware EB, Windham BG, Wright MJ, Yang J, Yu J, Ames D, Amin N, Amouyel P, Andreassen OA, Armstrong NJ, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, Böhmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, Dehghan A, Dick D, Dickinson D, Eriksson JG, Evangelou E, Faul JD, Ford I, Freimer NA, Gao H, Giegling I, Gillespie NA, Gordon SD, Gottesman RF, Griswold ME, Gudnason V, Harris TB, Hartmann AM, Hatzimanolis A, Heiss G, Holliday EG, Joshi PK, Kähönen M, Kardia SLR, Karlsson I, Kleineidam L, Knopman DS, Kochan NA, Konte B, Kwok JB, Le Hellard S, Lee T, Lehtimäki T, Li SC, Lill CM, Liu T, Koini M, London E, Longstreth WT Jr, Lopez OL, Loukola A, Luck T, Lundervold AJ, Lundquist A, Lyytikäinen LP, Martin NG, Montgomery GW, Murray AD, Need AC, Noordam R, Nyberg L, Ollier W, Papenberg G, Pattie A, Polasek O, Poldrack RA, Psaty BM, Reppermund S, Riedel-Heller SG, Rose RJ, Rotter JI, Roussos P, Rovio SP, Saba Y, Sabb FW, Sachdev PS, Satizabal CL, Schmid M, Scott RJ, Scult MA, Simino J, Slagboom PE, Smyrnis N, Soumaré A, Stefanis NC, Stott DJ, Straub RE, Sundet K, Taylor AM, Taylor KD, Tzoulaki I, Tzourio C, Uitterlinden A, Vitart V, Voineskos AN, Kaprio J, Wagner M, Wagner H, Weinhold L, Wen KH, Widen E, Yang Q, Zhao W, Adams HHH, Arking DE, Bilder RM, Bitsios P, Boerwinkle E, Chiba-Falek O, Corvin A, De Jager PL, Debette S, Donohoe G, Elliott P, Fitzpatrick AL, Gill M, Glahn DC, Hägg S, Hansell NK, Hariri AR, Ikram MK, Jukema JW, Vuoksimaa E, Keller MC, Kremen WS, Launer L, Lindenberger U, Palotie A, Pedersen NL, Pendleton N, Porteous DJ, Räikkönen K, Raitakari OT, Ramirez A, Reinvang I, Rudan I, Dan Rujescu, Schmidt R, Schmidt H, Schofield PW, Schofield PR, Starr JM, Steen VM, Trollor JN, Turner ST, Van Duijn CM, Villringer A, Weinberger DR, Weir DR, Wilson JF, Malhotra A, McIntosh AM, Gale CR, Seshadri S, Mosley TH Jr, Bressler J, Lencz T, Deary IJ.

Nat Commun. 2018 May 29;9(1):2098. doi: 10.1038/s41467-018-04362-x. Erratum in: Nat Commun. 2019 May 1;10(1):2068.

38.

Subregional volumes of the hippocampus in relation to cognitive function and risk of dementia.

Evans TE, Adams HHH, Licher S, Wolters FJ, van der Lugt A, Ikram MK, O'Sullivan MJ, Vernooij MW, Ikram MA.

Neuroimage. 2018 Sep;178:129-135. doi: 10.1016/j.neuroimage.2018.05.041. Epub 2018 May 18.

39.

Mild Cognitive Impairment and Dementia Show Contrasting Associations with Risk of Cancer.

van der Willik KD, Ruiter R, Wolters FJ, Ikram MK, Stricker BH, Hauptmann M, Compter A, Schagen SB, Ikram MA.

Neuroepidemiology. 2018;50(3-4):207-215. doi: 10.1159/000488892. Epub 2018 May 14.

40.

External validation of four dementia prediction models for use in the general community-dwelling population: a comparative analysis from the Rotterdam Study.

Licher S, Yilmaz P, Leening MJG, Wolters FJ, Vernooij MW, Stephan BCM, Ikram MK, Ikram MA.

Eur J Epidemiol. 2018 Jul;33(7):645-655. doi: 10.1007/s10654-018-0403-y. Epub 2018 May 8.

41.

Global cerebrovascular burden and long-term clinical outcomes in Asian elderly across the spectrum of cognitive impairment.

Xu X, Chan YH, Chan QL, Gyanwali B, Hilal S, Tan BY, Ikram MK, Venketasubramanian N, Chen CL.

Int Psychogeriatr. 2018 Sep;30(9):1355-1363. doi: 10.1017/S1041610217002952. Epub 2018 Apr 18.

PMID:
29665875
42.

Von Willebrand factor and ADAMTS13 activity in relation to risk of dementia: a population-based study.

Wolters FJ, Boender J, de Vries PS, Sonneveld MA, Koudstaal PJ, de Maat MP, Franco OH, Ikram MK, Leebeek FW, Ikram MA.

Sci Rep. 2018 Apr 3;8(1):5474. doi: 10.1038/s41598-018-23865-7.

43.

The effect of APOE and other common genetic variants on the onset of Alzheimer's disease and dementia: a community-based cohort study.

van der Lee SJ, Wolters FJ, Ikram MK, Hofman A, Ikram MA, Amin N, van Duijn CM.

Lancet Neurol. 2018 May;17(5):434-444. doi: 10.1016/S1474-4422(18)30053-X. Epub 2018 Mar 16. Erratum in: Lancet Neurol. 2018 Apr 25;:.

PMID:
29555425
44.

Caregiver-Reported Sleep Disturbances Are Associated With Behavioral and Psychological Symptoms in an Asian Elderly Cohort With Cognitive Impairment-No Dementia.

Xu X, Kan CN, Wong TY, Cheng CY, Ikram MK, Chen CL, Venketasubramanian N.

J Geriatr Psychiatry Neurol. 2018 Mar;31(2):70-75. doi: 10.1177/0891988718758203. Epub 2018 Mar 19.

PMID:
29554838
45.

Homocysteine and Cerebral Atrophy: The Epidemiology of Dementia in Singapore Study.

Tan B, Venketasubramanian N, Vrooman H, Cheng CY, Wong TY, Ikram MK, Chen C, Hilal S.

J Alzheimers Dis. 2018;62(2):877-885. doi: 10.3233/JAD-170796.

PMID:
29480177
46.

Low Accuracy of Brief Cognitive Tests in Tracking Longitudinal Cognitive Decline in an Asian Elderly Cohort.

Phua AKS, Hiu SKW, Goh WK, Ikram MK, Venketasubramanian N, Tan BY, Chen CL, Xu X.

J Alzheimers Dis. 2018;62(1):409-416. doi: 10.3233/JAD-170831.

PMID:
29439344
47.

Serum Hepatocyte Growth Factor Is Associated with Small Vessel Disease in Alzheimer's Dementia.

Zhu Y, Hilal S, Chai YL, Ikram MK, Venketasubramanian N, Chen CP, Lai MKP.

Front Aging Neurosci. 2018 Jan 23;10:8. doi: 10.3389/fnagi.2018.00008. eCollection 2018.

48.

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.

Flannick J, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, Robertson NR, Rayner NW, Cingolani P, Locke AE, Tajes JF, Highland HM, Dupuis J, Chines PS, Lindgren CM, Hartl C, Jackson AU, Chen H, Huyghe JR, van de Bunt M, Pearson RD, Kumar A, Müller-Nurasyid M, Grarup N, Stringham HM, Gamazon ER, Lee J, Chen Y, Scott RA, Below JE, Chen P, Huang J, Go MJ, Stitzel ML, Pasko D, Parker SCJ, Varga TV, Green T, Beer NL, Day-Williams AG, Ferreira T, Fingerlin T, Horikoshi M, Hu C, Huh I, Ikram MK, Kim BJ, Kim Y, Kim YJ, Kwon MS, Lee J, Lee S, Lin KH, Maxwell TJ, Nagai Y, Wang X, Welch RP, Yoon J, Zhang W, Barzilai N, Voight BF, Han BG, Jenkinson CP, Kuulasmaa T, Kuusisto J, Manning A, Ng MCY, Palmer ND, Balkau B, Stančáková A, Abboud HE, Boeing H, Giedraitis V, Prabhakaran D, Gottesman O, Scott J, Carey J, Kwan P, Grant G, Smith JD, Neale BM, Purcell S, Butterworth AS, Howson JMM, Lee HM, Lu Y, Kwak SH, Zhao W, Danesh J, Lam VKL, Park KS, Saleheen D, So WY, Tam CHT, Afzal U, Aguilar D, Arya R, Aung T, Chan E, Navarro C, Cheng CY, Palli D, Correa A, Curran JE, Rybin D, Farook VS, Fowler SP, Freedman BI, Griswold M, Hale DE, Hicks PJ, Khor CC, Kumar S, Lehne B, Thuillier D, Lim WY, Liu J, Loh M, Musani SK, Puppala S, Scott WR, Yengo L, Tan ST, Taylor HA, Thameem F, Wilson G, Wong TY, Njølstad PR, Levy JC, Mangino M, Bonnycastle LL, Schwarzmayr T, Fadista J, Surdulescu GL, Herder C, Groves CJ, Wieland T, Bork-Jensen J, Brandslund I, Christensen C, Koistinen HA, Doney ASF, Kinnunen L, Esko T, Farmer AJ, Hakaste L, Hodgkiss D, Kravic J, Lyssenko V, Hollensted M, Jørgensen ME, Jørgensen T, Ladenvall C, Justesen JM, Käräjämäki A, Kriebel J, Rathmann W, Lannfelt L, Lauritzen T, Narisu N, Linneberg A, Melander O, Milani L, Neville M, Orho-Melander M, Qi L, Qi Q, Roden M, Rolandsson O, Swift A, Rosengren AH, Stirrups K, Wood AR, Mihailov E, Blancher C, Carneiro MO, Maguire J, Poplin R, Shakir K, Fennell T, DePristo M, de Angelis MH, Deloukas P, Gjesing AP, Jun G, Nilsson P, Murphy J, Onofrio R, Thorand B, Hansen T, Meisinger C, Hu FB, Isomaa B, Karpe F, Liang L, Peters A, Huth C, O'Rahilly SP, Palmer CNA, Pedersen O, Rauramaa R, Tuomilehto J, Salomaa V, Watanabe RM, Syvänen AC, Bergman RN, Bharadwaj D, Bottinger EP, Cho YS, Chandak GR, Chan JCN, Chia KS, Daly MJ, Ebrahim SB, Langenberg C, Elliott P, Jablonski KA, Lehman DM, Jia W, Ma RCW, Pollin TI, Sandhu M, Tandon N, Froguel P, Barroso I, Teo YY, Zeggini E, Loos RJF, Small KS, Ried JS, DeFronzo RA, Grallert H, Glaser B, Metspalu A, Wareham NJ, Walker M, Banks E, Gieger C, Ingelsson E, Im HK, Illig T, Franks PW, Buck G, Trakalo J, Buck D, Prokopenko I, Mägi R, Lind L, Farjoun Y, Owen KR, Gloyn AL, Strauch K, Tuomi T, Kooner JS, Lee JY, Park T, Donnelly P, Morris AD, Hattersley AT, Bowden DW, Collins FS, Atzmon G, Chambers JC, Spector TD, Laakso M, Strom TM, Bell GI, Blangero J, Duggirala R, Tai ES, McVean G, Hanis CL, Wilson JG, Seielstad M, Frayling TM, Meigs JB, Cox NJ, Sladek R, Lander ES, Gabriel S, Mohlke KL, Meitinger T, Groop L, Abecasis G, Scott LJ, Morris AP, Kang HM, Altshuler D, Burtt NP, Florez JC, Boehnke M, McCarthy MI.

Sci Data. 2018 Jan 23;5:180002. doi: 10.1038/sdata.2018.2.

49.

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.

Flannick J, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, Robertson NR, Rayner NW, Cingolani P, Locke AE, Tajes JF, Highland HM, Dupuis J, Chines PS, Lindgren CM, Hartl C, Jackson AU, Chen H, Huyghe JR, van de Bunt M, Pearson RD, Kumar A, Müller-Nurasyid M, Grarup N, Stringham HM, Gamazon ER, Lee J, Chen Y, Scott RA, Below JE, Chen P, Huang J, Go MJ, Stitzel ML, Pasko D, Parker SCJ, Varga TV, Green T, Beer NL, Day-Williams AG, Ferreira T, Fingerlin T, Horikoshi M, Hu C, Huh I, Ikram MK, Kim BJ, Kim Y, Kim YJ, Kwon MS, Lee J, Lee S, Lin KH, Maxwell TJ, Nagai Y, Wang X, Welch RP, Yoon J, Zhang W, Barzilai N, Voight BF, Han BG, Jenkinson CP, Kuulasmaa T, Kuusisto J, Manning A, Ng MCY, Palmer ND, Balkau B, Stančáková A, Abboud HE, Boeing H, Giedraitis V, Prabhakaran D, Gottesman O, Scott J, Carey J, Kwan P, Grant G, Smith JD, Neale BM, Purcell S, Butterworth AS, Howson JMM, Lee HM, Lu Y, Kwak SH, Zhao W, Danesh J, Lam VKL, Park KS, Saleheen D, So WY, Tam CHT, Afzal U, Aguilar D, Arya R, Aung T, Chan E, Navarro C, Cheng CY, Palli D, Correa A, Curran JE, Rybin D, Farook VS, Fowler SP, Freedman BI, Griswold M, Hale DE, Hicks PJ, Khor CC, Kumar S, Lehne B, Thuillier D, Lim WY, Liu J, Loh M, Musani SK, Puppala S, Scott WR, Yengo L, Tan ST, Taylor HA, Thameem F, Wilson G, Wong TY, Njølstad PR, Levy JC, Mangino M, Bonnycastle LL, Schwarzmayr T, Fadista J, Surdulescu GL, Herder C, Groves CJ, Wieland T, Bork-Jensen J, Brandslund I, Christensen C, Koistinen HA, Doney ASF, Kinnunen L, Esko T, Farmer AJ, Hakaste L, Hodgkiss D, Kravic J, Lyssenko V, Hollensted M, Jørgensen ME, Jørgensen T, Ladenvall C, Justesen JM, Käräjämäki A, Kriebel J, Rathmann W, Lannfelt L, Lauritzen T, Narisu N, Linneberg A, Melander O, Milani L, Neville M, Orho-Melander M, Qi L, Qi Q, Roden M, Rolandsson O, Swift A, Rosengren AH, Stirrups K, Wood AR, Mihailov E, Blancher C, Carneiro MO, Maguire J, Poplin R, Shakir K, Fennell T, DePristo M, de Angelis MH, Deloukas P, Gjesing AP, Jun G, Nilsson P, Murphy J, Onofrio R, Thorand B, Hansen T, Meisinger C, Hu FB, Isomaa B, Karpe F, Liang L, Peters A, Huth C, O'Rahilly SP, Palmer CNA, Pedersen O, Rauramaa R, Tuomilehto J, Salomaa V, Watanabe RM, Syvänen AC, Bergman RN, Bharadwaj D, Bottinger EP, Cho YS, Chandak GR, Chan JC, Chia KS, Daly MJ, Ebrahim SB, Langenberg C, Elliott P, Jablonski KA, Lehman DM, Jia W, Ma RCW, Pollin TI, Sandhu M, Tandon N, Froguel P, Barroso I, Teo YY, Zeggini E, Loos RJF, Small KS, Ried JS, DeFronzo RA, Grallert H, Glaser B, Metspalu A, Wareham NJ, Walker M, Banks E, Gieger C, Ingelsson E, Im HK, Illig T, Franks PW, Buck G, Trakalo J, Buck D, Prokopenko I, Mägi R, Lind L, Farjoun Y, Owen KR, Gloyn AL, Strauch K, Tuomi T, Kooner JS, Lee JY, Park T, Donnelly P, Morris AD, Hattersley AT, Bowden DW, Collins FS, Atzmon G, Chambers JC, Spector TD, Laakso M, Strom TM, Bell GI, Blangero J, Duggirala R, Tai ES, McVean G, Hanis CL, Wilson JG, Seielstad M, Frayling TM, Meigs JB, Cox NJ, Sladek R, Lander ES, Gabriel S, Mohlke KL, Meitinger T, Groop L, Abecasis G, Scott LJ, Morris AP, Kang HM, Altshuler D, Burtt NP, Florez JC, Boehnke M, McCarthy MI.

Sci Data. 2017 Dec 19;4:170179. doi: 10.1038/sdata.2017.179. Erratum in: Sci Data. 2018 Jan 23;5:180002.

50.

Associations of Endogenous Estradiol and Testosterone Levels With Plaque Composition and Risk of Stroke in Subjects With Carotid Atherosclerosis.

Glisic M, Mujaj B, Rueda-Ochoa OL, Asllanaj E, Laven JSE, Kavousi M, Ikram MK, Vernooij MW, Ikram MA, Franco OH, Bos D, Muka T.

Circ Res. 2018 Jan 5;122(1):97-105. doi: 10.1161/CIRCRESAHA.117.311681. Epub 2017 Nov 2.

PMID:
29097437

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