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Items: 39


Seasonal influenza vaccines induced high levels of neutralizing cross-reactive antibody responses against different genetic group influenza A(H1N1)pdm09 viruses.

Haveri A, Ikonen N, Kantele A, Anttila VJ, Ruotsalainen E, Savolainen-Kopra C, Julkunen I.

Vaccine. 2019 May 6;37(20):2731-2740. doi: 10.1016/j.vaccine.2019.03.078. Epub 2019 Apr 4.


Deposition of respiratory virus pathogens on frequently touched surfaces at airports.

Ikonen N, Savolainen-Kopra C, Enstone JE, Kulmala I, Pasanen P, Salmela A, Salo S, Nguyen-Van-Tam JS, Ruutu P; PANDHUB consortium.

BMC Infect Dis. 2018 Aug 29;18(1):437. doi: 10.1186/s12879-018-3150-5.


Rapid detection and monitoring of human coronavirus infections.

Bruning AHL, Aatola H, Toivola H, Ikonen N, Savolainen-Kopra C, Blomqvist S, Pajkrt D, Wolthers KC, Koskinen JO.

New Microbes New Infect. 2018 May 9;24:52-55. doi: 10.1016/j.nmni.2018.04.007. eCollection 2018 Jul.


Low 2016/17 season vaccine effectiveness against hospitalised influenza A(H3N2) among elderly: awareness warranted for 2017/18 season.

Rondy M, Gherasim A, Casado I, Launay O, Rizzo C, Pitigoi D, Mickiene A, Marbus SD, Machado A, Syrjänen RK, Pem-Novose I, Horváth JK, Larrauri A, Castilla J, Vanhems P, Alfonsi V, Ivanciuc AE, Kuliese M, van Gageldonk-Lafeber R, Gomez V, Ikonen N, Lovric Z, Ferenczi A, Moren A; I-MOVE+ hospital working group.

Euro Surveill. 2017 Oct;22(41). doi: 10.2807/1560-7917.ES.2017.22.41.17-00645.


2015/16 seasonal vaccine effectiveness against hospitalisation with influenza A(H1N1)pdm09 and B among elderly people in Europe: results from the I-MOVE+ project.

Rondy M, Larrauri A, Casado I, Alfonsi V, Pitigoi D, Launay O, Syrjänen RK, Gefenaite G, Machado A, Vučina VV, Horváth JK, Paradowska-Stankiewicz I, Marbus SD, Gherasim A, Díaz-González JA, Rizzo C, Ivanciuc AE, Galtier F, Ikonen N, Mickiene A, Gomez V, Kurečić Filipović S, Ferenczi A, Korcinska MR, van Gageldonk-Lafeber R; I-MOVE+ hospital working group, Valenciano M.

Euro Surveill. 2017 Jul 27;22(30). pii: 30580. doi: 10.2807/1560-7917.ES.2017.22.30.30580.


Mid-season real-time estimates of seasonal influenza vaccine effectiveness in persons 65 years and older in register-based surveillance, Stockholm County, Sweden, and Finland, January 2017.

Hergens MP, Baum U, Brytting M, Ikonen N, Haveri A, Wiman Å, Nohynek H, Örtqvist Å.

Euro Surveill. 2017 Feb 23;22(8). pii: 30469. doi: 10.2807/1560-7917.ES.2017.22.8.30469. Erratum in: Euro Surveill. 2017 Mar 2;22(9):null.


Improving influenza virological surveillance in Europe: strain-based reporting of antigenic and genetic characterisation data, 11 European countries, influenza season 2013/14.

Broberg E, Hungnes O, Schweiger B, Prosenc K, Daniels R, Guiomar R, Ikonen N, Kossyvakis A, Pozo F, Puzelli S, Thomas I, Waters A, Wiman Å, Meijer A.

Euro Surveill. 2016 Oct 13;21(41). doi: 10.2807/1560-7917.ES.2016.21.41.30370. Erratum in: Euro Surveill. 2016 Oct 20;21(42):.


Effectiveness of the live attenuated and the inactivated influenza vaccine in two-year-olds - a nationwide cohort study Finland, influenza season 2015/16.

Nohynek H, Baum U, Syrjänen R, Ikonen N, Sundman J, Jokinen J.

Euro Surveill. 2016 Sep 22;21(38). doi: 10.2807/1560-7917.ES.2016.21.38.30346.


Comparative Analysis of Whole-Genome Sequences of Influenza A(H1N1)pdm09 Viruses Isolated from Hospitalized and Nonhospitalized Patients Identifies Missense Mutations That Might Be Associated with Patient Hospital Admissions in Finland during 2009 to 2014.

Mishel P, Ojala T, Benner C, Lakspere T, Bychkov D, Jalovaara P, Kakkola L, Kallio-Kokko H, Kantele A, Kankainen M, Ikonen N, Ripatti S, Julkunen I, Kainov DE.

Genome Announc. 2015 Jul 30;3(4). pii: e00676-15. doi: 10.1128/genomeA.00676-15.


Complete Genome Sequences of Influenza A/H1N1 Strains Isolated from Patients during the 2013-2014 Epidemic Season in Finland.

Jalovaara P, Mishel P, Kallio-Kokko H, Valkonen M, Kantele A, Ikonen N, Julkunen I, Kakkola L, Kutsaya A, Vuorinen T, Mattila P, Almusa H, Kainov D.

Genome Announc. 2015 Mar 12;3(2). pii: e01523-14. doi: 10.1128/genomeA.01523-14.


Reduced cross-protection against influenza A(H3N2) subgroup 3C.2a and 3C.3a viruses among Finnish healthcare workers vaccinated with 2013/14 seasonal influenza vaccine.

Haveri A, Ikonen N, Julkunen I, Kantele A, Anttila V, Ruotsalainen E, Nohynek H, Lyytikainen O, Savolainen-Kopra C.

Euro Surveill. 2015 Feb 5;20(5):21028. No abstract available.


Impact of influenza B lineage-level mismatch between trivalent seasonal influenza vaccines and circulating viruses, 1999-2012.

Heikkinen T, Ikonen N, Ziegler T.

Clin Infect Dis. 2014 Dec 1;59(11):1519-24. doi: 10.1093/cid/ciu664. Epub 2014 Aug 19.


Akt inhibitor MK2206 prevents influenza pH1N1 virus infection in vitro.

Denisova OV, Söderholm S, Virtanen S, Von Schantz C, Bychkov D, Vashchinkina E, Desloovere J, Tynell J, Ikonen N, Theisen LL, Nyman TA, Matikainen S, Kallioniemi O, Julkunen I, Muller CP, Saelens X, Verkhusha VV, Kainov DE.

Antimicrob Agents Chemother. 2014 Jul;58(7):3689-96. doi: 10.1128/AAC.02798-13. Epub 2014 Apr 21.


Autophagy is needed for the growth of pancreatic adenocarcinoma and has a cytoprotective effect against anticancer drugs.

Hashimoto D, Bläuer M, Hirota M, Ikonen NH, Sand J, Laukkarinen J.

Eur J Cancer. 2014 May;50(7):1382-90. doi: 10.1016/j.ejca.2014.01.011. Epub 2014 Feb 3.


Full-Genome Sequences of Influenza A(H1N1)pdm09 Viruses Isolated from Finnish Patients from 2009 to 2013.

Lakspere T, Tynell J, Kaloinen M, Vanlede M, Parsons A, Ikonen N, Kallio-Kokko H, Kantele A, Mattila P, Almusa H, Julkunen I, Kainov D, Kakkola L.

Genome Announc. 2014 Jan 16;2(1). pii: e01004-13. doi: 10.1128/genomeA.01004-13.


The first detection of influenza in the Finnish pig population: a retrospective study.

Nokireki T, Laine T, London L, Ikonen N, Huovilainen A.

Acta Vet Scand. 2013 Sep 18;55:69. doi: 10.1186/1751-0147-55-69.


[Influenza viruses--a challenge for vaccinations].

Julkunen I, Ikonen N, Strengell M, Ziegler T.

Duodecim. 2012;128(18):1919-28. Review. Finnish.


Antibody responses against influenza A(H1N1)pdm09 virus after sequential vaccination with pandemic and seasonal influenza vaccines in Finnish healthcare professionals.

Strengell M, Ikonen N, Ziegler T, Kantele A, Anttila VJ, Julkunen I.

Influenza Other Respir Viruses. 2013 May;7(3):431-8. doi: 10.1111/j.1750-2659.2012.00415.x. Epub 2012 Aug 23.


Detection of influenza A viruses with a portable real-time PCR instrument.

Mölsä M, Koskela KA, Rönkkö E, Ikonen N, Ziegler T, Nikkari S.

J Virol Methods. 2012 May;181(2):188-91. doi: 10.1016/j.jviromet.2012.02.001. Epub 2012 Feb 22.


Minor changes in the hemagglutinin of influenza A(H1N1)2009 virus alter its antigenic properties.

Strengell M, Ikonen N, Ziegler T, Julkunen I.

PLoS One. 2011;6(10):e25848. doi: 10.1371/journal.pone.0025848. Epub 2011 Oct 11.


Surveillance of influenza in Finland during the 2009 pandemic, 10 May 2009 to 8 March 2010.

Lyytikainen O, Kuusi M, Snellman M, Virtanen M, Eskola J, Ronkko E, Ikonen N, Julkunen I, Ziegler T, Ruutu P.

Euro Surveill. 2011 Jul 7;16(27). pii: 19908. No abstract available.


Validation and diagnostic application of NS and HA gene-specific real-time reverse transcription-PCR assays for detection of 2009 pandemic influenza A (H1N1) viruses in clinical specimens.

Rönkkö E, Ikonen N, Kontio M, Haanpää M, Kallio-Kokko H, Mannonen L, Lappalainen M, Julkunen I, Ziegler T.

J Clin Microbiol. 2011 May;49(5):2009-11. doi: 10.1128/JCM.00259-11. Epub 2011 Mar 2.


Genetic diversity of the 2009 pandemic influenza A(H1N1) viruses in Finland.

Ikonen N, Haanpää M, Rönkkö E, Lyytikäinen O, Kuusi M, Ruutu P, Kallio-Kokko H, Mannonen L, Lappalainen M, Ziegler T, Julkunen I.

PLoS One. 2010 Oct 20;5(10):e13329. doi: 10.1371/journal.pone.0013329.


Early oseltamivir treatment of influenza in children 1-3 years of age: a randomized controlled trial.

Heinonen S, Silvennoinen H, Lehtinen P, Vainionpää R, Vahlberg T, Ziegler T, Ikonen N, Puhakka T, Heikkinen T.

Clin Infect Dis. 2010 Oct 15;51(8):887-94. doi: 10.1086/656408.


High frequency of cross-reacting antibodies against 2009 pandemic influenza A(H1N1) virus among the elderly in Finland.

Ikonen N, Strengell M, Kinnunen L, Osterlund P, Pirhonen J, Broman M, Davidkin I, Ziegler T, Julkunen I.

Euro Surveill. 2010 Feb 4;15(5). pii: 19478.


Pandemic H1N1 2009 influenza A virus induces weak cytokine responses in human macrophages and dendritic cells and is highly sensitive to the antiviral actions of interferons.

Osterlund P, Pirhonen J, Ikonen N, Rönkkö E, Strengell M, Mäkelä SM, Broman M, Hamming OJ, Hartmann R, Ziegler T, Julkunen I.

J Virol. 2010 Feb;84(3):1414-22. doi: 10.1128/JVI.01619-09. Epub 2009 Nov 25.


Nuclear and nucleolar targeting of influenza A virus NS1 protein: striking differences between different virus subtypes.

Melén K, Kinnunen L, Fagerlund R, Ikonen N, Twu KY, Krug RM, Julkunen I.

J Virol. 2007 Jun;81(11):5995-6006. Epub 2007 Mar 21.


Influenza A/Fujian/411/02(H3N2)-lineage viruses in Finland: genetic diversity, epidemic activity and vaccination-induced antibody response.

Ikonen N, Pyhälä R, Toivonen M, Korpela H.

Arch Virol. 2006 Feb;151(2):241-54. Epub 2005 Sep 30.


Vaccination-induced HI antibody response to intraepidemic influenza A(H3N2) virus variants of the 1996-1997 epidemic season.

Pyhälä R, Ikonen N, Santanen R, Haanpää M, Visakorpi R, Jäppinen P, Valle M.

J Med Virol. 2001 Nov;65(3):584-9.


Recent influenza B viruses in Europe: a phylogenetic analysis.

Ikonen N, Kinnunen L, Forsten T, Pyhälä R.

Clin Diagn Virol. 1996 Jun;6(1):63-71.


Evolution of the HA1 domain of human influenza A (H1N1) virus: loss of glycosylation sites and occurrence of herald and conserved strains.

Pyhälä R, Ikonen N, Forsten T, Alanko S, Kinnunen L.

J Gen Virol. 1995 Jan;76 ( Pt 1):205-10.


Vaccination-induced HI antibody to influenza A(H1N1) viruses in poorly primed adults under circumstances of low antigenic drift.

Pyhälä R, Kinnunen L, Kumpulainen V, Ikonen N, Kleemola M, Cantell K.

Vaccine. 1993;11(10):1013-7.


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