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Items: 1 to 50 of 284

1.

Increase of arginine dimethylation correlates with the progression and prognosis of ALS.

Ikenaka K, Atsuta N, Maeda Y, Hotta Y, Nakamura R, Kawai K, Yokoi D, Hirakawa A, Taniguchi A, Morita M, Mizoguchi K, Mochizuki H, Kimura K, Katsuno M, Sobue G.

Neurology. 2019 Mar 13. pii: 10.1212/WNL.0000000000007311. doi: 10.1212/WNL.0000000000007311. [Epub ahead of print]

PMID:
30867270
2.

Region- and cell type-specific facilitation of synaptic function at destination synapses induced by oligodendrocyte depolarization.

Yamazaki Y, Abe Y, Shibata S, Shindo T, Fujii S, Ikenaka K, Tanaka KF.

J Neurosci. 2019 Mar 12. pii: 1619-18. doi: 10.1523/JNEUROSCI.1619-18.2019. [Epub ahead of print]

PMID:
30862665
3.

[Analysis of PEG-J associated complications in 14 adult patients treated with levodopa-carbidopa intestinal gel].

Shimamura M, Shinzaki S, Ikenaka K, Konaka K, Hirozawa D, Ishikura T, Hideshima M, Nakano T, Kitano T, Takehara T, Mochizuki H.

Rinsho Shinkeigaku. 2019 Feb 28. doi: 10.5692/clinicalneurol.cn-001195. [Epub ahead of print] Japanese.

PMID:
30814443
4.

Suppression of autophagic activity by Rubicon is a signature of aging.

Nakamura S, Oba M, Suzuki M, Takahashi A, Yamamuro T, Fujiwara M, Ikenaka K, Minami S, Tabata N, Yamamoto K, Kubo S, Tokumura A, Akamatsu K, Miyazaki Y, Kawabata T, Hamasaki M, Fukui K, Sango K, Watanabe Y, Takabatake Y, Kitajima TS, Okada Y, Mochizuki H, Isaka Y, Antebi A, Yoshimori T.

Nat Commun. 2019 Feb 19;10(1):847. doi: 10.1038/s41467-019-08729-6.

5.

Cathepsin C promotes microglia M1 polarization and aggravates neuroinflammation via activation of Ca2+-dependent PKC/p38MAPK/NF-κB pathway.

Liu Q, Zhang Y, Liu S, Liu Y, Yang X, Liu G, Shimizu T, Ikenaka K, Fan K, Ma J.

J Neuroinflammation. 2019 Jan 16;16(1):10. doi: 10.1186/s12974-019-1398-3.

6.

Mechanical regulation of oligodendrocyte morphology and maturation by the mechanosensor p130Cas.

Shimizu T, Osanai Y, Tanaka KF, Thai TQ, Abe M, Natsume R, Sakimura K, Ikenaka K.

J Neurochem. 2018 Dec 27. doi: 10.1111/jnc.14657. [Epub ahead of print]

PMID:
30589943
7.

News and ISN.

Ikenaka K.

J Neurochem. 2018 Nov;147(4):435. doi: 10.1111/jnc.14625. No abstract available.

PMID:
30474180
8.

Interactions between mitochondria and endoplasmic reticulum in demyelinated axons.

Thai TQ, Nguyen HB, Sui Y, Ikenaka K, Oda T, Ohno N.

Med Mol Morphol. 2018 Nov 17. doi: 10.1007/s00795-018-0212-0. [Epub ahead of print]

PMID:
30448927
9.

Neuroprotective effects of microglial P2Y1 receptors against ischemic neuronal injury.

Fukumoto Y, Tanaka KF, Parajuli B, Shibata K, Yoshioka H, Kanemaru K, Gachet C, Ikenaka K, Koizumi S, Kinouchi H.

J Cereb Blood Flow Metab. 2018 Oct 18:271678X18805317. doi: 10.1177/0271678X18805317. [Epub ahead of print]

PMID:
30334687
10.

Length of myelin internodes of individual oligodendrocytes is controlled by microenvironment influenced by normal and input-deprived axonal activities in sensory deprived mouse models.

Osanai Y, Shimizu T, Mori T, Hatanaka N, Kimori Y, Kobayashi K, Koyama S, Yoshimura Y, Nambu A, Ikenaka K.

Glia. 2018 Nov;66(11):2514-2525. doi: 10.1002/glia.23502. Epub 2018 Sep 21.

PMID:
30240035
11.

Axonal and neuronal degeneration in myelin diseases.

Ohno N, Ikenaka K.

Neurosci Res. 2019 Feb;139:48-57. doi: 10.1016/j.neures.2018.08.013. Epub 2018 Sep 1. Review.

PMID:
30179642
12.

[Levodopa-carbidopa intestinal gel treatment introduced by surgical gastrostomy in a patient of Parkinson's disease after Billroth II gastrojejunostomy].

Nakano T, Hirozawa D, Shimamura M, Sasaki T, Ikenaka K, Mochizuki H.

Rinsho Shinkeigaku. 2018 Sep 28;58(9):570-573. doi: 10.5692/clinicalneurol.cn-001150. Epub 2018 Aug 31. Japanese.

PMID:
30175807
13.

Cathepsin C modulates myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis.

Durose WW, Shimizu T, Li J, Abe M, Sakimura K, Chetsawang B, Tanaka KF, Suzumura A, Tohyama K, Ikenaka K.

J Neurochem. 2019 Feb;148(3):413-425. doi: 10.1111/jnc.14581. Epub 2018 Dec 3.

PMID:
30152001
14.

Branched Sialylated N-glycans Are Accumulated in Brain Synaptosomes and Interact with Siglec-H.

Handa-Narumi M, Yoshimura T, Konishi H, Fukata Y, Manabe Y, Tanaka K, Bao GM, Kiyama H, Fukase K, Ikenaka K.

Cell Struct Funct. 2018 Aug 25;43(2):141-152. doi: 10.1247/csf.18009. Epub 2018 Jul 20.

15.

Dysregulation of schizophrenia-related aquaporin 3 through disruption of paranode influences neuronal viability.

Kunisawa K, Shimizu T, Kushima I, Aleksic B, Mori D, Osanai Y, Kobayashi K, Taylor AM, Bhat MA, Hayashi A, Baba H, Ozaki N, Ikenaka K.

J Neurochem. 2018 Nov;147(3):395-408. doi: 10.1111/jnc.14553. Epub 2018 Aug 29.

PMID:
30025158
16.

Ectopic positioning of Bergmann glia and impaired cerebellar wiring in Mlc1-over-expressing mice.

Kikuchihara S, Sugio S, Tanaka KF, Watanabe T, Kano M, Yamazaki Y, Watanabe M, Ikenaka K.

J Neurochem. 2018 Nov;147(3):344-360. doi: 10.1111/jnc.14486. Epub 2018 Aug 8.

PMID:
29920672
17.

Anti-Depressant Fluoxetine Reveals its Therapeutic Effect Via Astrocytes.

Kinoshita M, Hirayama Y, Fujishita K, Shibata K, Shinozaki Y, Shigetomi E, Takeda A, Le HPN, Hayashi H, Hiasa M, Moriyama Y, Ikenaka K, Tanaka KF, Koizumi S.

EBioMedicine. 2018 Jun;32:72-83. doi: 10.1016/j.ebiom.2018.05.036. Epub 2018 Jun 8.

18.

Decreased number and increased volume with mitochondrial enlargement of cerebellar synaptic terminals in a mouse model of chronic demyelination.

Nguyen HB, Sui Y, Thai TQ, Ikenaka K, Oda T, Ohno N.

Med Mol Morphol. 2018 Dec;51(4):208-216. doi: 10.1007/s00795-018-0193-z. Epub 2018 May 23.

PMID:
29796936
19.

Correction: Disinhibition of Cathepsin C Caused by Cystatin F Deficiency Aggravates the Demyelination in a Cuprizone Model.

Liang J, Li N, Zhang Y, Hou C, Yang X, Shimizu T, Wang X, Ikenaka K, Fan K, Ma J.

Front Mol Neurosci. 2018 Apr 12;11:115. doi: 10.3389/fnmol.2018.00115. eCollection 2018.

20.

Aberrant astrocyte Ca2+ signals "AxCa signals" exacerbate pathological alterations in an Alexander disease model.

Saito K, Shigetomi E, Yasuda R, Sato R, Nakano M, Tashiro K, Tanaka KF, Ikenaka K, Mikoshiba K, Mizuta I, Yoshida T, Nakagawa M, Mizuno T, Koizumi S.

Glia. 2018 May;66(5):1053-1067. doi: 10.1002/glia.23300. Epub 2018 Jan 31.

PMID:
29383757
21.

Role of Purinergic Receptor P2Y1 in Spatiotemporal Ca2+ Dynamics in Astrocytes.

Shigetomi E, Hirayama YJ, Ikenaka K, Tanaka KF, Koizumi S.

J Neurosci. 2018 Feb 7;38(6):1383-1395. doi: 10.1523/JNEUROSCI.2625-17.2017. Epub 2018 Jan 5.

22.

Strong sonic hedgehog signaling in the mouse ventral spinal cord is not required for oligodendrocyte precursor cell (OPC) generation but is necessary for correct timing of its generation.

Hashimoto H, Jiang W, Yoshimura T, Moon KH, Bok J, Ikenaka K.

Neurochem Int. 2018 Oct;119:178-183. doi: 10.1016/j.neuint.2017.11.003. Epub 2017 Nov 6.

PMID:
29122585
23.

Minocycline Directly Enhances the Self-Renewal of Adult Neural Precursor Cells.

Kuroda A, Fuchigami T, Fuke S, Koyama N, Ikenaka K, Hitoshi S.

Neurochem Res. 2018 Jan;43(1):219-226. doi: 10.1007/s11064-017-2422-6. Epub 2017 Oct 28.

PMID:
29081002
24.

Origin of Oligodendrocytes in the Vertebrate Optic Nerve: A Review.

Ono K, Hirahara Y, Gotoh H, Nomura T, Takebayashi H, Yamada H, Ikenaka K.

Neurochem Res. 2018 Jan;43(1):3-11. doi: 10.1007/s11064-017-2404-8. Epub 2017 Oct 4. Review.

PMID:
28980095
25.

Oligodendrocyte-Neuron Interactions: Impact on Myelination and Brain Function.

Shimizu T, Osanai Y, Ikenaka K.

Neurochem Res. 2018 Jan;43(1):190-194. doi: 10.1007/s11064-017-2387-5. Epub 2017 Sep 16.

PMID:
28918515
26.

Polymorphic regulation of mitochondrial fission and fusion modifies phenotypes of microglia in neuroinflammation.

Katoh M, Wu B, Nguyen HB, Thai TQ, Yamasaki R, Lu H, Rietsch AM, Zorlu MM, Shinozaki Y, Saitoh Y, Saitoh S, Sakoh T, Ikenaka K, Koizumi S, Ransohoff RM, Ohno N.

Sci Rep. 2017 Jul 10;7(1):4942. doi: 10.1038/s41598-017-05232-0.

27.

Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia via P2Y1 Receptor Downregulation.

Shinozaki Y, Shibata K, Yoshida K, Shigetomi E, Gachet C, Ikenaka K, Tanaka KF, Koizumi S.

Cell Rep. 2017 May 9;19(6):1151-1164. doi: 10.1016/j.celrep.2017.04.047.

28.

Sulfatase 2 Modulates Fate Change from Motor Neurons to Oligodendrocyte Precursor Cells through Coordinated Regulation of Shh Signaling with Sulfatase 1.

Jiang W, Ishino Y, Hashimoto H, Keino-Masu K, Masu M, Uchimura K, Kadomatsu K, Yoshimura T, Ikenaka K.

Dev Neurosci. 2017;39(5):361-374. doi: 10.1159/000464284. Epub 2017 May 11.

29.

Oligodendrocyte precursor cells in the mouse optic nerve originate in the preoptic area.

Ono K, Yoshii K, Tominaga H, Gotoh H, Nomura T, Takebayashi H, Ikenaka K.

Brain Struct Funct. 2017 Jul;222(5):2441-2448. doi: 10.1007/s00429-017-1394-2. Epub 2017 Mar 14.

PMID:
28293728
30.

The balance between cathepsin C and cystatin F controls remyelination in the brain of Plp1-overexpressing mouse, a chronic demyelinating disease model.

Shimizu T, Wisessmith W, Li J, Abe M, Sakimura K, Chetsawang B, Sahara Y, Tohyama K, Tanaka KF, Ikenaka K.

Glia. 2017 Jun;65(6):917-930. doi: 10.1002/glia.23134. Epub 2017 Mar 2.

PMID:
28251676
31.

GlcNAc6ST-1 regulates sulfation of N-glycans and myelination in the peripheral nervous system.

Yoshimura T, Hayashi A, Handa-Narumi M, Yagi H, Ohno N, Koike T, Yamaguchi Y, Uchimura K, Kadomatsu K, Sedzik J, Kitamura K, Kato K, Trapp BD, Baba H, Ikenaka K.

Sci Rep. 2017 Feb 10;7:42257. doi: 10.1038/srep42257.

32.

Altered Tau Isoform Ratio Caused by Loss of FUS and SFPQ Function Leads to FTLD-like Phenotypes.

Ishigaki S, Fujioka Y, Okada Y, Riku Y, Udagawa T, Honda D, Yokoi S, Endo K, Ikenaka K, Takagi S, Iguchi Y, Sahara N, Takashima A, Okano H, Yoshida M, Warita H, Aoki M, Watanabe H, Okado H, Katsuno M, Sobue G.

Cell Rep. 2017 Jan 31;18(5):1118-1131. doi: 10.1016/j.celrep.2017.01.013.

33.

Disinhibition of Cathepsin C Caused by Cystatin F Deficiency Aggravates the Demyelination in a Cuprizone Model.

Liang J, Li N, Zhang Y, Hou C, Yang X, Shimizu T, Wang X, Ikenaka K, Fan K, Ma J.

Front Mol Neurosci. 2016 Dec 21;9:152. doi: 10.3389/fnmol.2016.00152. eCollection 2016. Erratum in: Front Mol Neurosci. 2018 Apr 12;11:115.

34.

Histological detection of dynamic glial responses in the dysmyelinating Tabby-jimpy mutant brain.

Ikeda M, Hossain MI, Zhou L, Horie M, Ikenaka K, Horii A, Takebayashi H.

Anat Sci Int. 2018 Jan;93(1):119-127. doi: 10.1007/s12565-016-0383-5. Epub 2016 Nov 25.

PMID:
27888476
35.

YAP functions as a mechanotransducer in oligodendrocyte morphogenesis and maturation.

Shimizu T, Osanai Y, Tanaka KF, Abe M, Natsume R, Sakimura K, Ikenaka K.

Glia. 2017 Feb;65(2):360-374. doi: 10.1002/glia.23096. Epub 2016 Nov 3.

PMID:
27807898
36.

Rabies virus-mediated oligodendrocyte labeling reveals a single oligodendrocyte myelinates axons from distinct brain regions.

Osanai Y, Shimizu T, Mori T, Yoshimura Y, Hatanaka N, Nambu A, Kimori Y, Koyama S, Kobayashi K, Ikenaka K.

Glia. 2017 Jan;65(1):93-105. doi: 10.1002/glia.23076. Epub 2016 Oct 19.

PMID:
27759175
37.

Astrocyte-mediated infantile-onset leukoencephalopathy mouse model.

Sugio S, Tohyama K, Oku S, Fujiyoshi K, Yoshimura T, Hikishima K, Yano R, Fukuda T, Nakamura M, Okano H, Watanabe M, Fukata M, Ikenaka K, Tanaka KF.

Glia. 2017 Jan;65(1):150-168. doi: 10.1002/glia.23084. Epub 2016 Oct 17.

PMID:
27748972
38.

Origin of oligodendrocytes in mammalian forebrains: a revised perspective.

Naruse M, Ishizaki Y, Ikenaka K, Tanaka A, Hitoshi S.

J Physiol Sci. 2017 Jan;67(1):63-70. doi: 10.1007/s12576-016-0479-7. Epub 2016 Aug 29. Review.

39.

Microglia-induced activation of non-canonical Wnt signaling aggravates neurodegeneration in demyelinating disorders.

Shimizu T, Smits R, Ikenaka K.

Mol Cell Biol. 2016 Aug 22. pii: MCB.00139-16. [Epub ahead of print]

40.

Keratan Sulfate Regulates the Switch from Motor Neuron to Oligodendrocyte Generation During Development of the Mouse Spinal Cord.

Hashimoto H, Ishino Y, Jiang W, Yoshimura T, Takeda-Uchimura Y, Uchimura K, Kadomatsu K, Ikenaka K.

Neurochem Res. 2016 Feb;41(1-2):450-62. doi: 10.1007/s11064-016-1861-9. Epub 2016 Feb 11.

PMID:
26869039
41.

The Dorsoventral Boundary of the Germinal Zone is a Specialized Niche for the Generation of Cortical Oligodendrocytes during a Restricted Temporal Window.

Naruse M, Ishino Y, Kumar A, Ono K, Takebayashi H, Yamaguchi M, Ishizaki Y, Ikenaka K, Hitoshi S.

Cereb Cortex. 2016 Jun;26(6):2800-2810. doi: 10.1093/cercor/bhv141. Epub 2015 Jun 23.

PMID:
26108613
42.

Oligodendrocyte generation during mouse development.

Takebayashi H, Ikenaka K.

Glia. 2015 Aug;63(8):1350-6. doi: 10.1002/glia.22863. Epub 2015 May 25. Review.

PMID:
26013243
43.

The induction of neuronal death by up-regulated microglial cathepsin H in LPS-induced neuroinflammation.

Fan K, Li D, Zhang Y, Han C, Liang J, Hou C, Xiao H, Ikenaka K, Ma J.

J Neuroinflammation. 2015 Mar 19;12:54. doi: 10.1186/s12974-015-0268-x.

44.

Determination of major sialylated N-glycans and identification of branched sialylated N-glycans that dynamically change their content during development in the mouse cerebral cortex.

Torii T, Yoshimura T, Narumi M, Hitoshi S, Takaki Y, Tsuji S, Ikenaka K.

Glycoconj J. 2014 Dec;31(9):671-83. doi: 10.1007/s10719-014-9566-2. Epub 2014 Nov 23.

45.

Disruption of actin-binding domain-containing Dystonin protein causes dystonia musculorum in mice.

Horie M, Watanabe K, Bepari AK, Nashimoto J, Araki K, Sano H, Chiken S, Nambu A, Ono K, Ikenaka K, Kakita A, Yamamura K, Takebayashi H.

Eur J Neurosci. 2014 Nov;40(10):3458-71. doi: 10.1111/ejn.12711. Epub 2014 Sep 6.

PMID:
25195653
46.

Pioglitazone suppresses neuronal and muscular degeneration caused by polyglutamine-expanded androgen receptors.

Iida M, Katsuno M, Nakatsuji H, Adachi H, Kondo N, Miyazaki Y, Tohnai G, Ikenaka K, Watanabe H, Yamamoto M, Kishida K, Sobue G.

Hum Mol Genet. 2015 Jan 15;24(2):314-29. doi: 10.1093/hmg/ddu445. Epub 2014 Aug 28.

PMID:
25168383
47.

Mechanisms for interferon-α-induced depression and neural stem cell dysfunction.

Zheng LS, Hitoshi S, Kaneko N, Takao K, Miyakawa T, Tanaka Y, Xia H, Kalinke U, Kudo K, Kanba S, Ikenaka K, Sawamoto K.

Stem Cell Reports. 2014 Jun 26;3(1):73-84. doi: 10.1016/j.stemcr.2014.05.015. eCollection 2014 Jul 8.

48.

Increased adenosine levels in mice expressing mutant glial fibrillary acidic protein in astrocytes result in failure of induction of LTP reversal (depotentiation) in hippocampal CA1 neurons.

Fujii S, Tanaka KF, Ikenaka K, Yamazaki Y.

Brain Res. 2014 Aug 26;1578:1-13. doi: 10.1016/j.brainres.2014.07.005. Epub 2014 Jul 10.

PMID:
25017946
49.

Development of the prethalamus is crucial for thalamocortical projection formation and is regulated by Olig2.

Ono K, Clavairoly A, Nomura T, Gotoh H, Uno A, Armant O, Takebayashi H, Zhang Q, Shimamura K, Itohara S, Parras CM, Ikenaka K.

Development. 2014 May;141(10):2075-84. doi: 10.1242/dev.097790.

50.

Short- and long-term functional plasticity of white matter induced by oligodendrocyte depolarization in the hippocampus.

Yamazaki Y, Fujiwara H, Kaneko K, Hozumi Y, Xu M, Ikenaka K, Fujii S, Tanaka KF.

Glia. 2014 Aug;62(8):1299-312. doi: 10.1002/glia.22681. Epub 2014 Apr 22.

PMID:
24756966

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