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An autopsy case of primary lateral sclerosis with Alzheimer's disease.

Nakamura T, Kon T, Kawarabayashi T, Wakabayashi K, Ikeda Y, Shoji M.

J Neurol Sci. 2020 Mar 20;412:116792. doi: 10.1016/j.jns.2020.116792. [Epub ahead of print] No abstract available.


Safety and Efficacy of Prasugrel in Elderly/Low Body Weight Japanese Patients with Ischemic Stroke: Randomized PRASTRO-II.

Kitagawa K, Toyoda K, Kitazono T, Nishikawa M, Nanto S, Ikeda Y, Abe K, Ogawa A.

Cerebrovasc Dis. 2020 Mar 24:1-8. doi: 10.1159/000506825. [Epub ahead of print]


A founder Alu insertion in RP1 gene in Japanese patients with retinitis pigmentosa.

Nishiguchi KM, Fujita K, Ikeda Y, Kunikata H, Koyanagi Y, Akiyama M, Abe T, Wada Y, Sonoda KH, Nakazawa T.

Jpn J Ophthalmol. 2020 Mar 19. doi: 10.1007/s10384-020-00732-5. [Epub ahead of print]


Associations between Depressive Symptoms and Satisfaction with Meaningful Activities in Community-Dwelling Japanese Older Adults.

Maruta M, Makizako H, Ikeda Y, Miyata H, Nakamura A, Han G, Shimokihara S, Tokuda K, Kubozono T, Ohishi M, Tomori K, Tabira T.

J Clin Med. 2020 Mar 14;9(3). pii: E795. doi: 10.3390/jcm9030795.


Outcomes of Endoscopic Submucosal Dissection for Subepithelial Lesions Localized Within the Submucosa, Including Neuroendocrine Tumors: A Multicenter Prospective Study.

Kobara H, Miyaoka Y, Ikeda Y, Yamada T, Takata M, Fujihara S, Nishiyama N, Fujita K, Tani J, Kobayashi N, Chiyo T, Yachida T, Okano K, Suzuki Y, Mori H, Masaki T.

J Gastrointestin Liver Dis. 2020 Mar 13;29(1):41-49. doi: 10.15403/jgld-510.


Safety and Efficacy of Long-Term Ripasudil 0.4% Instillation for the Reduction of Intraocular Pressure in Japanese Open-Angle Glaucoma Patients.

Maruyama Y, Ikeda Y, Mori K, Yoshii K, Ueno M, Sotozono C, Kinoshita S.

J Ocul Pharmacol Ther. 2020 Mar 12. doi: 10.1089/jop.2019.0125. [Epub ahead of print]


γ-Glutamylcysteine synthetase and γ-glutamyl transferase as differential enzymatic sources of γ-glutamylpeptides in mice.

Kobayashi S, Ikeda Y, Shigeno Y, Konno H, Fujii J.

Amino Acids. 2020 Mar 13. doi: 10.1007/s00726-020-02835-2. [Epub ahead of print]


Tropical Octopus Abdopus aculeatus Can Learn to Recognize Real and Virtual Symbolic Objects.

Kawashima S, Takei K, Yoshikawa S, Yasumuro H, Ikeda Y.

Biol Bull. 2020 Feb;238(1):12-24. doi: 10.1086/707420. Epub 2020 Feb 20.


Involvement of the α-helical and Src homology 3 domains in the molecular assembly and enzymatic activity of human α1,6-fucosyltransferase, FUT8.

Ihara H, Okada T, Taniguchi N, Ikeda Y.

Biochim Biophys Acta Gen Subj. 2020 Mar 5;1864(7):129596. doi: 10.1016/j.bbagen.2020.129596. [Epub ahead of print]


Impact of high-density mapping on outcome of the second ablation for atrial fibrillation.

Ikeda Y, Kato R, Mori H, Tsutsui K, Goto K, Nagase T, Tanaka S, Asano S, Tawara M, Yukino M, Hasegawa S, Nakano S, Iwanaka S, Muramatsu T, Matsumoto K.

J Interv Card Electrophysiol. 2020 Mar 6. doi: 10.1007/s10840-020-00716-y. [Epub ahead of print]


The Effect of Dapagliflozin Treatment on Epicardial Adipose Tissue Volume and P-Wave Indices: An Ad-hoc Analysis of The Previous Randomized Clinical Trial.

Sato T, Aizawa Y, Yuasa S, Fujita S, Ikeda Y, Okabe M.

J Atheroscler Thromb. 2020 Feb 28. doi: 10.5551/jat.48009. [Epub ahead of print]


Association of CRX genotypes and retinal phenotypes confounded by variable expressivity and electronegative electroretinogram.

Nishiguchi KM, Kunikata H, Fujita K, Hashimoto K, Koyanagi Y, Akiyama M, Ikeda Y, Momozawa Y, Sonoda KH, Murakami A, Wada Y, Nakazawa T.

Clin Exp Ophthalmol. 2020 Feb 29. doi: 10.1111/ceo.13743. [Epub ahead of print]


Effect of functional lateral shift of the mandible on hyaluronic acid metabolism related to lubrication of temporomandibular joint in growing rats.

Guo X, Watari I, Ikeda Y, Yang W, Ono T.

Eur J Orthod. 2020 Feb 29. pii: cjaa012. doi: 10.1093/ejo/cjaa012. [Epub ahead of print]


Aberrant activation of bone marrow Ly6C high monocytes in diabetic mice contributes to impaired glucose tolerance.

Ikeda Y, Sonoda N, Bachuluun B, Kimura S, Ogawa Y, Inoguchi T.

PLoS One. 2020 Feb 25;15(2):e0229401. doi: 10.1371/journal.pone.0229401. eCollection 2020.


Chorea-acanthocytosis with a novel mutation in the vacuolar protein sorting 13 homolog a gene: A case report.

Tada Y, Hamaguchi T, Ikeda Y, Iwasa K, Nishida Y, Nakamura M, Sano A, Yamada M.

J Neurol Sci. 2020 Feb 20;412:116731. doi: 10.1016/j.jns.2020.116731. [Epub ahead of print] No abstract available.


Phase II study in progress to verify improved response with mFOLFOX6 after exposure to an immune checkpoint inhibitor in advanced gastric cancer.

Ann H, Manaka D, Konishi S, Ikeda Y, Ota T, Kudo R, Kawaguchi K, Sasaki N, Hamasu S, Nishitai R.

Ann Oncol. 2019 Jul;30 Suppl 4:iv57. doi: 10.1093/annonc/mdz155.207. Epub 2019 Dec 4. No abstract available.


Hepatic sinusoidal obstruction syndrome (HSOS) in cStage III gastric cancer patients undergoing neoadjuvant chemotherapy with oxaliplatin: a retrospective cohort study.

Kawaguchi K, Manaka D, Konishi S, Ikeda Y, Ota T, Kudo R, Sasaki N, Hamasu S, Nishitai R.

Ann Oncol. 2019 Jul;30 Suppl 4:iv51. doi: 10.1093/annonc/mdz155.187. Epub 2019 Dec 4. No abstract available.


Prognostic implications of free cancer cells in gastric juice in gastric cancer patients who underwent surgery: a prospective cohort study.

Manaka D, Konishi S, Kawaguchi K, Ikeda Y, Ota T, Kudo R, Ann H, Sasaki N, Hamasu S, Nishitai R.

Ann Oncol. 2019 Jul;30 Suppl 4:iv28. doi: 10.1093/annonc/mdz155.102. Epub 2019 Dec 4. No abstract available.


Phase II study of neoadjuvant chemotherapy with S-1 plus oxaliplatin at a dose of 130mg/m2 (nacG-SOX130) in clinical(c)Stage III gastric cancer.

Konishi S, Manaka D, Ikeda Y, Ota T, Kudo R, Ann H, Kawaguchi K, Sasaki N, Hamasu S, Nishitai R.

Ann Oncol. 2019 Jul;30 Suppl 4:iv27-iv28. doi: 10.1093/annonc/mdz155.101. Epub 2019 Dec 4. No abstract available.


Novel Hydrophilic Camptothecin Derivatives Conjugated to Branched Glycerol Trimer Suppress Tumor Growth without Causing Diarrhea in Murine Xenograft Models of Human Lung Cancer.

Tsuchihashi Y, Abe S, Miyamoto L, Tsunematsu H, Izumi T, Hatano A, Okuno H, Yamane M, Yasuoka T, Ikeda Y, Tsuchiya K.

Mol Pharm. 2020 Apr 6;17(4):1049-1058. doi: 10.1021/acs.molpharmaceut.9b00249. Epub 2020 Mar 4.


Development of an IL-17A DNA Vaccine to Treat Systemic Lupus Erythematosus in Mice.

Koriyama H, Ikeda Y, Nakagami H, Shimamura M, Yoshida S, Rakugi H, Morishita R.

Vaccines (Basel). 2020 Feb 12;8(1). pii: E83. doi: 10.3390/vaccines8010083.


A Case of Anti-LRP4 Antibody-associated Myasthenia Gravis with a Rare Complication of Thymoma Successfully Treated by Thymectomy.

Aoki S, Nagashima K, Furuta M, Makioka K, Fujita Y, Saito K, Kashima T, Nakajima N, Ikota H, Higuchi O, Ikeda Y.

Intern Med. 2020 Feb 12. doi: 10.2169/internalmedicine.3828-19. [Epub ahead of print]


Clinical assessment of motor imagery and physical function in mild stroke patients.

Sakai K, Ikeda Y.

J Phys Ther Sci. 2019 Dec;31(12):992-996. doi: 10.1589/jpts.31.992. Epub 2019 Dec 3.


Effect of Obesity on Hematotoxicity Induced by Carboplatin and Paclitaxel Combination Therapy in Patients with Gynecological Cancer.

Ando Y, Hayashi T, Shiouchi H, Tanaka C, Ito K, Nishibe S, Miyata N, Horiba R, Yanagi H, Fujii T, Kawada K, Ikeda Y, Yamada S.

Biol Pharm Bull. 2020 Apr 1;43(4):669-674. doi: 10.1248/bpb.b19-00916. Epub 2020 Feb 7.


Mechanoresponsive and lubricating changes of mandibular condylar cartilage associated with mandibular lateral shift and recovery in the growing rat.

Yang W, Podyma-Inoue KA, Yonemitsu I, Watari I, Ikeda Y, Guo X, Watabe T, Ono T.

Clin Oral Investig. 2020 Feb 7. doi: 10.1007/s00784-020-03225-4. [Epub ahead of print]


Targeting Insulin-Like Growth Factor 1 Receptor Delays M-Phase Progression and Synergizes with Aurora B Inhibition to Suppress Cell Proliferation.

Yamagishi A, Ikeda Y, Ikeuchi M, Yuki R, Saito Y, Nakayama Y.

Int J Mol Sci. 2020 Feb 5;21(3). pii: E1058. doi: 10.3390/ijms21031058.


Longitudinal seasonal variations of intraocular pressure in primary open-angle glaucoma patients as revealed by real-world data.

Ikeda Y, Ueno M, Yoshii K, Nakano M, Sotozono C, Kinoshita S, Mori K.

Acta Ophthalmol. 2020 Feb 3. doi: 10.1111/aos.14365. [Epub ahead of print] No abstract available.


Plasma-activated medium promotes autophagic cell death along with alteration of the mTOR pathway.

Yoshikawa N, Liu W, Nakamura K, Yoshida K, Ikeda Y, Tanaka H, Mizuno M, Toyokuni S, Hori M, Kikkawa F, Kajiyama H.

Sci Rep. 2020 Jan 31;10(1):1614. doi: 10.1038/s41598-020-58667-3.


Neonatal eosinophilic gastroenteritis mimicking hypertrophic pyloric stenosis.

Yokoyama S, Nakaoka T, Nukada T, Ikeda Y, Hara S.

Pediatr Int. 2020 Jan;62(1):99-101. doi: 10.1111/ped.14041. No abstract available.


Ring-Fused Firefly Luciferins: Expanded Palette of Near-Infrared Emitting Bioluminescent Substrates.

Ikeda Y, Nomoto T, Hiruta Y, Nishiyama N, Citterio D.

Anal Chem. 2020 Mar 17;92(6):4235-4243. doi: 10.1021/acs.analchem.9b04562. Epub 2020 Feb 4.


Reconstructed uterine length is critical for the prevention of cervical stenosis following abdominal trachelectomy in cervical cancer patients.

Nakajima T, Kasuga A, Hara-Yamashita A, Ikeda Y, Asai-Sato M, Nakao T, Hayashi C, Takeya C, Adachi K, Tsuruga T, Matsumoto Y, Arimoto T, Nagamatsu T, Oda K, Komatsu A, Chishima F, Osuga Y, Fujii T, Kawana K.

J Obstet Gynaecol Res. 2020 Feb;46(2):328-336. doi: 10.1111/jog.14153. Epub 2020 Jan 20.


Percutaneous Simple Lead Traction Is a Feasible and Effective Method for Right Ventricular Lead Perforations.

Mori H, Kato R, Ikeda Y, Tsutsui K, Hasegawa S, Tanaka S, Iwanaga S, Nakano S, Muramatsu T, Sumitomo N, Matsumoto K.

Int Heart J. 2020 Jan 31;61(1):54-59. doi: 10.1536/ihj.19-326. Epub 2020 Jan 17.


Association between changes in the mRNA expression of platelet-activating factor receptor in peripheral blood mononuclear cells and progression of diabetic nephropathy.

Ghavidel Darestani S, Kurano M, Shinnakasu A, Yamamoto K, Dochi Y, Uemura K, Ikeda Y, Arimura A, Arimura H, Kikuchi A, Hashiguchi H, Deguchi T, Nishio Y.

Diabetol Int. 2019 Apr 11;11(1):11-18. doi: 10.1007/s13340-019-00394-w. eCollection 2020 Jan.


An anti-oxidative cell culture dish inhibits intracellular reactive oxygen species accumulation and modulates pluripotency-associated gene expression in mesenchymal stem cells.

Ikeda Y, Inuzuka N, Goto M, Akaike T, Nagasaki Y.

J Biomed Mater Res A. 2020 May;108(5):1058-1063. doi: 10.1002/jbm.a.36881. Epub 2020 Mar 4.


Recent Achievements and Current Interests in Research on the Characterization and Quality Control of Biopharmaceuticals in Japan.

Ishii-Watabe A, Shibata H, Suetomo H, Ikeda Y, Telikepalli S, Kiyoshi M, Hayashi Y, Muto T, Tanaka Y, Ueda S, Iwura T, Saitoh S, Aoyama M, Harazono A, Hyuga M, Goda Y, Torisu T, Uchiyama S.

J Pharm Sci. 2020 Jan 9. pii: S0022-3549(20)30006-X. doi: 10.1016/j.xphs.2020.01.001. [Epub ahead of print]


The determinants and outcomes of myocardial injury after transcatheter aortic-valve implantation: SAPIEN 3 study.

Sato T, Aizawa Y, Yuasa S, Taya Y, Fujita S, Ikeda Y, Kitazawa H, Takahashi M, Okabe M.

Cardiovasc Revasc Med. 2019 Dec 28. pii: S1553-8389(19)30829-2. doi: 10.1016/j.carrev.2019.12.028. [Epub ahead of print]


Quantitative analysis of operators' flow line in the cell culture for controlled manual operation.

Kanie K, Sasaki H, Ikeda Y, Tamada M, Togawa F, Kato R.

Regen Ther. 2019 May 14;12:43-54. doi: 10.1016/j.reth.2019.04.008. eCollection 2019 Dec 15.


Clinical Significance of Ubiquitin-associated Protein 2-like in Patients With Uterine Cervical Cancer.

Yoshida K, Kajiyama H, Inami E, Tamauchi S, Ikeda Y, Yoshikawa N, Nishino K, Utsumi F, Niimi K, Suzuki S, Shibata K, Nawa A, Kikkawa F.

In Vivo. 2020 Jan-Feb;34(1):109-116. doi: 10.21873/invivo.11751.


Rho-associated protein kinase and cyclophilin a are involved in inorganic phosphate-induced calcification signaling in vascular smooth muscle cells.

Tsuda T, Imanishi M, Oogoshi M, Goda M, Kihira Y, Horinouchi Y, Zamami Y, Ishizawa K, Ikeda Y, Hashimoto I, Tamaki T, Izawa-Ishizawa Y.

J Pharmacol Sci. 2020 Mar;142(3):109-115. doi: 10.1016/j.jphs.2019.12.005. Epub 2019 Dec 16.


Risk factors for superficial digital flexor tendinopathy in Thoroughbred racing horses in Japan.

Ikeda Y, Ishihara A, Nakajima M, Yamada K.

J Equine Sci. 2019;30(4):93-98. doi: 10.1294/jes.30.93. Epub 2019 Dec 18.


A multicenter, randomized, double-blind, controlled study to evaluate the efficacy and safety of dantrolene on ventricular arrhythmia as well as mortality and morbidity in patients with chronic heart failure (SHO-IN trial): rationale and design.

Kobayashi S, Wakeyama T, Ono S, Ikeda Y, Omura M, Oda T, Hisamatsu Y, Seki K, Satoh A, Hiromoto M, Akashi S, Uchida K, Harada M, Furutani Y, Nakamura Y, Kohno M, Kawamura S, Obayashi M, Michishige H, Yano M.

J Cardiol. 2020 Apr;75(4):454-461. doi: 10.1016/j.jjcc.2019.08.020. Epub 2019 Dec 20.


FOXO3a Activation by HDAC Class IIa Inhibition Induces Cell Cycle Arrest in Pancreatic Cancer Cells.

Usami M, Kikuchi S, Takada K, Ono M, Sugama Y, Arihara Y, Hayasaka N, Nakamura H, Ikeda Y, Hirakawa M, Yoshida M, Miyanishi K, Kobune M, Kato J.

Pancreas. 2020 Jan;49(1):135-142. doi: 10.1097/MPA.0000000000001462.


A historical case of primary triglyceride deposit cardiomyovasculopathy.

Tanaka M, Ikeda Y, Li M, Zaima N, Kawahara Y, Watanabe K, Inaba T, Kobayashi K, Noguchi H, Yamada S, Hao H, Hirano KI.

Pathol Int. 2020 Jan;70(1):58-61. doi: 10.1111/pin.12884. Epub 2019 Dec 18. No abstract available.


Elevated serum procalcitonin levels and their association with the prognosis of patients with liver cirrhosis.

Sato S, Sato S, Tsuzura H, Ikeda Y, Hayashida S, Takahashi S, Amano N, Murata A, Shimada Y, Iijima K, Nagahara A, Genda T.

Eur J Gastroenterol Hepatol. 2019 Dec 16. doi: 10.1097/MEG.0000000000001644. [Epub ahead of print]


Safe administration of rituximab for follicular lymphoma after obinutuzumab infusion-related reaction.

Hara T, Suzuki R, Ohno A, Yamakawa K, Yamagishi Y, Sugiyama Y, Sobajima T, Yamada R, Matsumoto R, Ikeda Y, Murayama M, Tsurumi H.

Int J Hematol. 2020 Apr;111(4):585-590. doi: 10.1007/s12185-019-02793-w. Epub 2019 Dec 17.


Relationship among Activities of Daily Living, Nutritional Status, and 90 Day Readmission in Elderly Patients with Heart Failure.

Kitamura M, Izawa KP, Yaekura M, Mimura Y, Ikeda Y, Nagashima H, Brubaker PH.

Int J Environ Res Public Health. 2019 Dec 12;16(24). pii: E5068. doi: 10.3390/ijerph16245068.


Differential and quantitative neuroimaging characteristics of inclusion body myositis.

Furuta M, Furuta N, Nagashima K, Fujita Y, Tsushima Y, Ikeda Y.

J Clin Neurosci. 2020 Feb;72:244-251. doi: 10.1016/j.jocn.2019.11.029. Epub 2019 Dec 12.


Direct comparison of retinal structure and function in retinitis pigmentosa by co-registering microperimetry and optical coherence tomography.

Funatsu J, Murakami Y, Nakatake S, Akiyama M, Fujiwara K, Shimokawa S, Tachibana T, Hisatomi T, Koyanagi Y, Momozawa Y, Sonoda KH, Ikeda Y.

PLoS One. 2019 Dec 12;14(12):e0226097. doi: 10.1371/journal.pone.0226097. eCollection 2019.


Risk factors for cancer-associated thrombosis in patients undergoing treatment with immune checkpoint inhibitors.

Ando Y, Hayashi T, Sugimoto R, Nishibe S, Ito K, Kawada K, Ikeda Y, Yamada S, Imaizumi K.

Invest New Drugs. 2019 Dec 10. doi: 10.1007/s10637-019-00881-6. [Epub ahead of print]


Pseudoaneurysm with an aortopulmonary fistula that appeared 3 years after total arch replacement.

Ikeshita T, Ito H, Ikeda Y, Sakata K.

Ann Thorac Surg. 2019 Nov 30. pii: S0003-4975(19)31816-8. doi: 10.1016/j.athoracsur.2019.10.028. [Epub ahead of print] No abstract available.


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