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Cataract-preventing contact lens for in vivo imaging of mouse retina.

Ikeda W, Nakatani T, Uemura A.

Biotechniques. 2018 Aug;65(2):101-104. doi: 10.2144/btn-2018-0040.


Anti-Fractalkine Antibody Suppresses Joint Destruction by Inhibiting Migration of Osteoclast Precursors to the Synovium in Experimental Arthritis.

Hoshino-Negishi K, Ohkuro M, Nakatani T, Kuboi Y, Nishimura M, Ida Y, Kakuta J, Hamaguchi A, Kumai M, Kamisako T, Sugiyama F, Ikeda W, Ishii N, Yasuda N, Imai T.

Arthritis Rheumatol. 2018 Aug 6. doi: 10.1002/art.40688. [Epub ahead of print]


Obesity Suppresses Cell-Competition-Mediated Apical Elimination of RasV12-Transformed Cells from Epithelial Tissues.

Sasaki A, Nagatake T, Egami R, Gu G, Takigawa I, Ikeda W, Nakatani T, Kunisawa J, Fujita Y.

Cell Rep. 2018 Apr 24;23(4):974-982. doi: 10.1016/j.celrep.2018.03.104.


Imaging Window Device for Subcutaneous Implantation Tumor.

Ikeda W, Sasai K, Akagi T.

Methods Mol Biol. 2018;1763:153-163. doi: 10.1007/978-1-4939-7762-8_15.


Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown.

Ogura S, Kurata K, Hattori Y, Takase H, Ishiguro-Oonuma T, Hwang Y, Ahn S, Park I, Ikeda W, Kusuhara S, Fukushima Y, Nara H, Sakai H, Fujiwara T, Matsushita J, Ema M, Hirashima M, Minami T, Shibuya M, Takakura N, Kim P, Miyata T, Ogura Y, Uemura A.

JCI Insight. 2017 Feb 9;2(3):e90905. doi: 10.1172/jci.insight.90905.


Nectin and junctional adhesion molecule are critical cell adhesion molecules for the apico-basal alignment of adherens and tight junctions in epithelial cells.

Yamada T, Kuramitsu K, Rikitsu E, Kurita S, Ikeda W, Takai Y.

Genes Cells. 2013 Nov;18(11):985-98. doi: 10.1111/gtc.12091. Epub 2013 Sep 24.


Binding between the junctional proteins afadin and PLEKHA7 and implication in the formation of adherens junction in epithelial cells.

Kurita S, Yamada T, Rikitsu E, Ikeda W, Takai Y.

J Biol Chem. 2013 Oct 11;288(41):29356-68. doi: 10.1074/jbc.M113.453464. Epub 2013 Aug 29.


Rab13 small G protein and junctional Rab13-binding protein (JRAB) orchestrate actin cytoskeletal organization during epithelial junctional development.

Sakane A, Abdallah AA, Nakano K, Honda K, Ikeda W, Nishikawa Y, Matsumoto M, Matsushita N, Kitamura T, Sasaki T.

J Biol Chem. 2012 Dec 14;287(51):42455-68. doi: 10.1074/jbc.M112.383653. Epub 2012 Oct 24.


Difficulties in receiving a medical consultation among Japanese workers with mental health problems.

Okubo S, Yokoyama K, Suzuki M, Tani I, Ikeda W, Kitamura F.

J Occup Health. 2012;54(1):51-5. Epub 2011 Dec 10.


Interaction of nectin-like molecule 2 with integrin alpha6beta4 and inhibition of disassembly of integrin alpha6beta4 from hemidesmosomes.

Mizutani K, Kawano S, Minami A, Waseda M, Ikeda W, Takai Y.

J Biol Chem. 2011 Oct 21;286(42):36667-76. doi: 10.1074/jbc.M110.200535. Epub 2011 Aug 31.


Does the Japanese Society for Hygiene need its own Code of Conduct? A comparison of the responses of councilors and junior members based on a questionnaire survey.

Ikeda W, Inaba Y, Takeshita T, Yoshida K, Ogoshi K, Okamoto K.

Environ Health Prev Med. 2011 May;16(3):178-84. doi: 10.1007/s12199-010-0175-9. Epub 2010 Sep 23.


The active site structure of nitrided and oxynitrided graphite as a cathode catalyst in a fuel cell.

Tominaga H, Ikeda W, Nagai M.

Phys Chem Chem Phys. 2011 Feb 21;13(7):2659-62. doi: 10.1039/c0cp02209h. Epub 2010 Dec 22.


Necl-5/PVR enhances PDGF-induced attraction of growing microtubules to the plasma membrane of the leading edge of moving NIH3T3 cells.

Minami A, Mizutani K, Waseda M, Kajita M, Miyata M, Ikeda W, Takai Y.

Genes Cells. 2010 Nov;15(11):1123-35. doi: 10.1111/j.1365-2443.2010.01450.x. Epub 2010 Oct 21.


Interaction of integrin alpha(6)beta(4) with ErbB3 and implication in heregulin-induced ErbB3/ErbB2-mediated DNA synthesis.

Kawano S, Mizutani K, Miyata M, Ikeda W, Takai Y.

Genes Cells. 2010 Sep 1;15(9):995-1001. doi: 10.1111/j.1365-2443.2010.01438.x. Epub 2010 Jul 29.


[Attitudes towards the code of conduct for scientists among council members of the Japanese Society for Hygiene].

Ikeda W, Inaba Y, Yoshida K, Takeshita T, Ogoshi K, Okamoto K.

Nihon Eiseigaku Zasshi. 2010 Jan;65(1):60-74. Japanese.


Involvement of the interaction of afadin with ZO-1 in the formation of tight junctions in Madin-Darby canine kidney cells.

Ooshio T, Kobayashi R, Ikeda W, Miyata M, Fukumoto Y, Matsuzawa N, Ogita H, Takai Y.

J Biol Chem. 2010 Feb 12;285(7):5003-12. doi: 10.1074/jbc.M109.043760. Epub 2009 Dec 12.


Silencing of ErbB3/ErbB2 signaling by immunoglobulin-like Necl-2.

Kawano S, Ikeda W, Kishimoto M, Ogita H, Takai Y.

J Biol Chem. 2009 Aug 28;284(35):23793-805. doi: 10.1074/jbc.M109.025155. Epub 2009 Jun 26.


Roles of cell adhesion molecules nectin and nectin-like molecule-5 in the regulation of cell movement and proliferation.

Ogita H, Ikeda W, Takai Y.

J Microsc. 2008 Sep;231(3):455-65. doi: 10.1111/j.1365-2818.2008.02058.x. Review.


Nectins and nectin-like molecules: roles in contact inhibition of cell movement and proliferation.

Takai Y, Miyoshi J, Ikeda W, Ogita H.

Nat Rev Mol Cell Biol. 2008 Aug;9(8):603-15. doi: 10.1038/nrm2457. Review.


The immunoglobulin-like cell adhesion molecule nectin and its associated protein afadin.

Takai Y, Ikeda W, Ogita H, Rikitake Y.

Annu Rev Cell Dev Biol. 2008;24:309-42. doi: 10.1146/annurev.cellbio.24.110707.175339. Review.


Novel role of nectin: implication in the co-localization of JAM-A and claudin-1 at the same cell-cell adhesion membrane domain.

Kuramitsu K, Ikeda W, Inoue N, Tamaru Y, Takai Y.

Genes Cells. 2008 Aug;13(8):797-805. doi: 10.1111/j.1365-2443.2008.01206.x. Epub 2008 Jun 28.


Sequential activation of Rap1 and Rac1 small G proteins by PDGF locally at leading edges of NIH3T3 cells.

Takahashi M, Rikitake Y, Nagamatsu Y, Hara T, Ikeda W, Hirata K, Takai Y.

Genes Cells. 2008 Jun;13(6):549-69. doi: 10.1111/j.1365-2443.2008.01187.x. Epub 2008 Apr 17.


Roles of Necl-5/poliovirus receptor and Rho-associated kinase (ROCK) in the regulation of transformation of integrin alpha(V)beta(3)-based focal complexes into focal adhesions.

Nagamatsu Y, Rikitake Y, Takahashi M, Deki Y, Ikeda W, Hirata K, Takai Y.

J Biol Chem. 2008 May 23;283(21):14532-41. doi: 10.1074/jbc.M801647200. Epub 2008 Mar 25.


Interaction and localization of Necl-5 and PDGF receptor beta at the leading edges of moving NIH3T3 cells: Implications for directional cell movement.

Amano H, Ikeda W, Kawano S, Kajita M, Tamaru Y, Inoue N, Minami Y, Yamada A, Takai Y.

Genes Cells. 2008 Mar;13(3):269-84. doi: 10.1111/j.1365-2443.2008.01167.x.


The public's attitudes towards the use of genetic information for medical purposes and its related factors in Japan.

Ikeda W.

Community Genet. 2008;11(1):18-25. doi: 10.1159/000111636. Epub 2008 Jan 15.


Establishment of cell polarity by afadin during the formation of embryoid bodies.

Komura H, Ogita H, Ikeda W, Mizoguchi A, Miyoshi J, Takai Y.

Genes Cells. 2008 Jan;13(1):79-90. doi: 10.1111/j.1365-2443.2007.01150.x.


The roles of nectins in cell adhesions: cooperation with other cell adhesion molecules and growth factor receptors.

Sakisaka T, Ikeda W, Ogita H, Fujita N, Takai Y.

Curr Opin Cell Biol. 2007 Oct;19(5):593-602. Epub 2007 Oct 17. Review.


Interaction of cancer cells with platelets mediated by Necl-5/poliovirus receptor enhances cancer cell metastasis to the lungs.

Morimoto K, Satoh-Yamaguchi K, Hamaguchi A, Inoue Y, Takeuchi M, Okada M, Ikeda W, Takai Y, Imai T.

Oncogene. 2008 Jan 10;27(3):264-73. Epub 2007 Jul 16.


Necl-5/poliovirus receptor interacts in cis with integrin alphaVbeta3 and regulates its clustering and focal complex formation.

Minami Y, Ikeda W, Kajita M, Fujito T, Amano H, Tamaru Y, Kuramitsu K, Sakamoto Y, Monden M, Takai Y.

J Biol Chem. 2007 Jun 22;282(25):18481-96. Epub 2007 Apr 19.


Involvement of up-regulated Necl-5/Tage4/PVR/CD155 in the loss of contact inhibition in transformed NIH3T3 cells.

Minami Y, Ikeda W, Kajita M, Fujito T, Monden M, Takai Y.

Biochem Biophys Res Commun. 2007 Jan 26;352(4):856-60. Epub 2006 Nov 29.


Inhibition of cell movement and proliferation by cell-cell contact-induced interaction of Necl-5 with nectin-3.

Fujito T, Ikeda W, Kakunaga S, Minami Y, Kajita M, Sakamoto Y, Monden M, Takai Y.

J Cell Biol. 2005 Oct 10;171(1):165-73.


Expression of nectin-2 in mouse granulosa cells.

Kawagishi R, Tahara M, Morishige K, Sakata M, Tasaka K, Ikeda W, Morimoto K, Takai Y, Murata Y.

Eur J Obstet Gynecol Reprod Biol. 2005 Jul 1;121(1):71-6.


Roles and modes of action of nectins in cell-cell adhesion.

Irie K, Shimizu K, Sakisaka T, Ikeda W, Takai Y.

Semin Cell Dev Biol. 2004 Dec;15(6):643-56. Review.


Enhancement of serum- and platelet-derived growth factor-induced cell proliferation by Necl-5/Tage4/poliovirus receptor/CD155 through the Ras-Raf-MEK-ERK signaling.

Kakunaga S, Ikeda W, Shingai T, Fujito T, Yamada A, Minami Y, Imai T, Takai Y.

J Biol Chem. 2004 Aug 27;279(35):36419-25. Epub 2004 Jun 22.


Nectin-like molecule-5/Tage4 enhances cell migration in an integrin-dependent, Nectin-3-independent manner.

Ikeda W, Kakunaga S, Takekuni K, Shingai T, Satoh K, Morimoto K, Takeuchi M, Imai T, Takai Y.

J Biol Chem. 2004 Apr 23;279(17):18015-25. Epub 2004 Feb 9.


Roles of nectins in cell adhesion, signaling and polarization.

Irie K, Shimizu K, Sakisaka T, Ikeda W, Takai Y.

Handb Exp Pharmacol. 2004;(165):343-72. doi: 10.1007/978-3-540-68170-0_11.


Nectins and nectin-like molecules: roles in cell adhesion, migration, and polarization.

Takai Y, Irie K, Shimizu K, Sakisaka T, Ikeda W.

Cancer Sci. 2003 Aug;94(8):655-67. Review.


Implications of nectin-like molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in cell-cell adhesion and transmembrane protein localization in epithelial cells.

Shingai T, Ikeda W, Kakunaga S, Morimoto K, Takekuni K, Itoh S, Satoh K, Takeuchi M, Imai T, Monden M, Takai Y.

J Biol Chem. 2003 Sep 12;278(37):35421-7. Epub 2003 Jun 25.


Tage4/Nectin-like molecule-5 heterophilically trans-interacts with cell adhesion molecule Nectin-3 and enhances cell migration.

Ikeda W, Kakunaga S, Itoh S, Shingai T, Takekuni K, Satoh K, Inoue Y, Hamaguchi A, Morimoto K, Takeuchi M, Imai T, Takai Y.

J Biol Chem. 2003 Jul 25;278(30):28167-72. Epub 2003 May 11.


Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial cells of developing mouse.

Takekuni K, Ikeda W, Fujito T, Morimoto K, Takeuchi M, Monden M, Takai Y.

J Biol Chem. 2003 Feb 21;278(8):5497-500. Epub 2003 Jan 5.


ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions.

Asada M, Irie K, Morimoto K, Yamada A, Ikeda W, Takeuchi M, Takai Y.

J Biol Chem. 2003 Feb 7;278(6):4103-11. Epub 2002 Nov 21.


Involvement of nectin in the localization of junctional adhesion molecule at tight junctions.

Fukuhara A, Irie K, Nakanishi H, Takekuni K, Kawakatsu T, Ikeda W, Yamada A, Katata T, Honda T, Sato T, Shimizu K, Ozaki H, Horiuchi H, Kita T, Takai Y.

Oncogene. 2002 Oct 31;21(50):7642-55.


Nectin couples cell-cell adhesion and the actin scaffold at heterotypic testicular junctions.

Ozaki-Kuroda K, Nakanishi H, Ohta H, Tanaka H, Kurihara H, Mueller S, Irie K, Ikeda W, Sakai T, Wimmer E, Nishimune Y, Takai Y.

Curr Biol. 2002 Jul 9;12(13):1145-50.


Restoration of E-cadherin-based cell-cell adhesion by overexpression of nectin in HSC-39 cells, a human signet ring cell gastric cancer cell line.

Peng YF, Mandai K, Nakanishi H, Ikeda W, Asada M, Momose Y, Shibamoto S, Yanagihara K, Shiozaki H, Monden M, Takeichi M, Takai Y.

Oncogene. 2002 Jun 13;21(26):4108-19.


Association of frabin with specific actin and membrane structures.

Kim Y, Ikeda W, Nakanishi H, Tanaka Y, Takekuni K, Itoh S, Monden M, Takai Y.

Genes Cells. 2002 Apr;7(4):413-20.

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