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Items: 1 to 50 of 3767

1.

GABAergic function in the lateral hypothalamus regulates feeding behavior: Possible mediation via orexin.

Yonemochi N, Ardianto C, Ueda D, Kamei J, Ikeda H.

Neuropsychopharmacol Rep. 2019 Oct 16. doi: 10.1002/npr2.12080. [Epub ahead of print]

2.

Exceptionally rapid response to pembrolizumab in a SMARCA4-deficient thoracic sarcoma overexpressing PD-L1: A case report.

Takada K, Sugita S, Murase K, Kikuchi T, Oomori G, Ito R, Hayasaka N, Miyanishi K, Iyama S, Ikeda H, Kobune M, Emori M, Kato J, Hasegawa T.

Thorac Cancer. 2019 Oct 16. doi: 10.1111/1759-7714.13215. [Epub ahead of print]

PMID:
31617320
3.

Real-world experience of 12-week DAA regimen of glecaprevir and pibrentasvir in patients with chronic HCV infection.

Toyoda H, Atsukawa M, Watanabe T, Nakamuta M, Uojima H, Nozaki A, Takaguchi K, Fujioka S, Iio E, Shima T, Akahane T, Fukunishi S, Asano T, Michitaka K, Tsuji K, Abe H, Mikami S, Okubo H, Okubo T, Shimada N, Ishikawa T, Moriya A, Tani J, Morishita A, Ogawa C, Tachi Y, Ikeda H, Yamashita N, Yasuda S, Chuma M, Tsutsui A, Hiraoka A, Ikegami T, Genda T, Tsubota A, Masaki T, Tanaka Y, Iwakiri K, Kumada T.

J Gastroenterol Hepatol. 2019 Oct 14. doi: 10.1111/jgh.14874. [Epub ahead of print]

PMID:
31609495
4.

Hepatic FATP5 expression is associated with histological progression and loss of hepatic fat in NAFLD patients.

Enooku K, Tsutsumi T, Kondo M, Fujiwara N, Sasako T, Shibahara J, Kado A, Okushin K, Fujinaga H, Nakagomi R, Minami T, Sato M, Uchino K, Nakagawa H, Kondo Y, Asaoka Y, Tateishi R, Ueki K, Ikeda H, Yoshida H, Moriya K, Yotsuyanagi H, Kadowaki T, Koike K.

J Gastroenterol. 2019 Oct 10. doi: 10.1007/s00535-019-01633-2. [Epub ahead of print]

PMID:
31602526
5.

Trends in sepsis care in Japan: comparison of two sepsis cohort studies conducted by the Japanese Association for Acute Medicine.

Fujishima S, Gando S, Saitoh D, Kushimoto S, Ogura H, Abe T, Shiraishi A, Mayumi T, Sasaki J, Kotani J, Takeyama N, Tsuruta R, Takuma K, Yamashita N, Shiraishi SI, Ikeda H, Shiino Y, Tarui T, Nakada TA, Hifumi T, Otomo Y, Okamoto K, Sakamoto Y, Hagiwara A, Masuno T, Ueyama M, Fujimi S, Yamakawa K, Umemura Y.

Acute Med Surg. 2019 Aug 7;6(4):425-427. doi: 10.1002/ams2.449. eCollection 2019 Oct.

6.

Biodegradable Flow Diverter for the Treatment of Intracranial Aneurysms: A Pilot Study Using a Rabbit Aneurysm Model.

Nishi H, Ishii A, Ono I, Abekura Y, Ikeda H, Arai D, Yamao Y, Okawa M, Kikuchi T, Nakakura A, Miyamoto S.

J Am Heart Assoc. 2019 Oct 15;8(20):e014074. doi: 10.1161/JAHA.119.014074. Epub 2019 Oct 4.

7.

Clinical Characterization of Vonoprazan-Refractory Gastroesophageal Reflux Disease.

Hamada S, Ihara E, Ikeda H, Muta K, Ogino H, Chinen T, Tanaka Y, Ogawa Y.

Digestion. 2019 Oct 2:1-8. doi: 10.1159/000503340. [Epub ahead of print]

PMID:
31578027
8.

Evaluation of Therapeutic Target Gene Expression Based on Residual Cancer Burden Classification After Neoadjuvant Chemotherapy for HER2-Negative Breast Cancer.

Takahashi Y, Iwamoto T, Suzuki Y, Kajiwara Y, Hatono M, Tsukioki T, Kawada K, Kochi M, Ikeda H, Shien T, Taira N, Matsuoka J, Doihara H, Toyooka S.

Clin Breast Cancer. 2019 Sep 9. pii: S1526-8209(19)30643-3. doi: 10.1016/j.clbc.2019.07.001. [Epub ahead of print]

PMID:
31570267
9.

Correlation between microstructure of CAD/CAM composites and the silanization effect on adhesive bonding.

Yano HT, Ikeda H, Nagamatsu Y, Masaki C, Hosokawa R, Shimizu H.

J Mech Behav Biomed Mater. 2019 Sep 18;101:103441. doi: 10.1016/j.jmbbm.2019.103441. [Epub ahead of print]

PMID:
31569037
10.

Expression Profile of Cell Cycle-Related Genes in Human Fibroblasts Exposed Simultaneously to Radiation and Simulated Microgravity.

Ikeda H, Muratani M, Hidema J, Hada M, Fujiwara K, Souda H, Yoshida Y, Takahashi A.

Int J Mol Sci. 2019 Sep 26;20(19). pii: E4791. doi: 10.3390/ijms20194791.

11.

Assessment of prognosis in immunoglobulin light chain amyloidosis patients with severe heart failure: a predictive value of right ventricular function.

Nagano N, Yano T, Fujita Y, Kouzu H, Koyama M, Ikeda H, Yasui K, Muranaka A, Nishikawa R, Takahashi R, Kishiue N, Yuda S, Miura T.

Heart Vessels. 2019 Sep 26. doi: 10.1007/s00380-019-01513-y. [Epub ahead of print]

PMID:
31559459
12.

Hydroxylation of Steroids by A Microbial Substrate-Promiscuous Cytochrome P450 105D7: Key Arginine Residues for Rational Design.

Ma B, Wang Q, Ikeda H, Zhang C, Xu LH.

Appl Environ Microbiol. 2019 Sep 20. pii: AEM.01530-19. doi: 10.1128/AEM.01530-19. [Epub ahead of print]

PMID:
31540985
13.

Dopaminergic mechanisms in the lateral hypothalamus regulate feeding behavior in association with neuropeptides.

Yonemochi N, Ardianto C, Yang L, Yamamoto S, Ueda D, Kamei J, Waddington JL, Ikeda H.

Biochem Biophys Res Commun. 2019 Nov 12;519(3):547-552. doi: 10.1016/j.bbrc.2019.09.037. Epub 2019 Sep 16.

PMID:
31537386
14.

Reproducibility, responsiveness and validation of the Tampa Scale for Kinesiophobia in patients with ACL injuries.

Huang H, Nagao M, Arita H, Shiozawa J, Nishio H, Kobayashi Y, Kaneko H, Nagayama M, Saita Y, Ishijima M, Takazawa Y, Ikeda H, Kaneko K.

Health Qual Life Outcomes. 2019 Sep 11;17(1):150. doi: 10.1186/s12955-019-1217-7.

15.

Synthesis and antitumor activity of novel pyridinium fullerene derivatives.

Yasuno T, Ohe T, Ikeda H, Takahashi K, Nakamura S, Mashino T.

Int J Nanomedicine. 2019 Aug 7;14:6325-6337. doi: 10.2147/IJN.S212045. eCollection 2019.

16.

Efficacy of endoscopic sinus surgery for eosinophilic chronic rhinosinusitis with asthma.

Ohta N, Suzuki Y, Ikeda H, Noguchi N, Kakuta R, Suzuki T, Ikeda R, Yamazaki M, Saito Y, Kusano Y, Ishida Y, Shoji F, Yoshioka H, Ono J, Takahashi T, Nakamura Y, Ohno I, Izuhara K.

Allergol Int. 2019 Sep 5. pii: S1323-8930(19)30133-9. doi: 10.1016/j.alit.2019.08.004. [Epub ahead of print] No abstract available.

17.

Bright light exposure advances consolidation of motor skill accuracy in humans.

Yoshiike T, Honma M, Ikeda H, Kuriyama K.

Neurobiol Learn Mem. 2019 Sep 3;166:107084. doi: 10.1016/j.nlm.2019.107084. [Epub ahead of print]

PMID:
31491556
18.

Two cases of primary supratentorial intracranial rhabdomyosarcoma with DICER1 mutation which may belong to a "spindle cell sarcoma with rhabdomyosarcoma-like feature, DICER1 mutant".

Sakaguchi M, Nakano Y, Honda-Kitahara M, Kinoshita M, Tanaka S, Oishi M, Noguchi K, Fukuda M, Maeba H, Watanabe T, Hayashi Y, Ikeda H, Minato H, Ichimura K, Nojima T, Nakada M.

Brain Tumor Pathol. 2019 Oct;36(4):174-182. doi: 10.1007/s10014-019-00352-z. Epub 2019 Sep 5.

PMID:
31487013
19.

Endoscopic transpapillary gallbladder stenting using a newly designed plastic stent for acute cholecystitis.

Nakahara K, Michikawa Y, Morita R, Suetani K, Morita N, Sato J, Tsuji K, Ikeda H, Matsunaga K, Watanabe T, Matsumoto N, Kobayashi S, Otsubo T, Itoh F.

Endosc Int Open. 2019 Sep;7(9):E1105-E1114. doi: 10.1055/a-0747-5668. Epub 2019 Aug 29.

20.

Resolvin E3 attenuates allergic airway inflammation via the interleukin-23-interleukin-17A pathway.

Sato M, Aoki-Saito H, Fukuda H, Ikeda H, Koga Y, Yatomi M, Tsurumaki H, Maeno T, Saito T, Nakakura T, Mori T, Yanagawa M, Abe M, Sako Y, Dobashi K, Ishizuka T, Yamada M, Shuto S, Hisada T.

FASEB J. 2019 Aug 30:fj201900283R. doi: 10.1096/fj.201900283R. [Epub ahead of print]

PMID:
31469599
21.
22.

The P wave morphology in lead V7 on the synthesized 18-lead ECG is a useful parameter for identifying arrhythmias originating from the right inferior pulmonary vein.

Hisazaki K, Miyazaki S, Hasegawa K, Kaseno K, Amaya N, Shiomi Y, Tama N, Ikeda H, Fukuoka Y, Morishita T, Ishida K, Uzui H, Tada H.

Heart Vessels. 2019 Aug 22. doi: 10.1007/s00380-019-01483-1. [Epub ahead of print]

PMID:
31440830
23.

Patient-derived xenograft models of non-small cell lung cancer for evaluating targeted drug sensitivity and resistance.

Kita K, Fukuda K, Takahashi H, Tanimoto A, Nishiyama A, Arai S, Takeuchi S, Yamashita K, Ohtsubo K, Otani S, Yanagimura N, Suzuki C, Ikeda H, Tamura M, Matsumoto I, Yano S.

Cancer Sci. 2019 Oct;110(10):3215-3224. doi: 10.1111/cas.14171.

24.

Identification of novel biomarkers of hepatocellular carcinoma by a high definition mass spectrometry; UHPLC-QTOF/MS and DESI-MSI.

Nagai K, Uranbileg B, Chen Z, Fujioka A, Yamazaki T, Matsmoto Y, Tsukamoto H, Ikeda H, Yatomi Y, Chiba H, Hui SP, Nakazawa T, Saito R, Koshiba S, Aoki J, Saigusa D, Tomioka Y.

Rapid Commun Mass Spectrom. 2019 Aug 14. doi: 10.1002/rcm.8551. [Epub ahead of print]

PMID:
31412144
25.

Identifying Sepsis Populations Benefitting from Anticoagulant Therapy: A Prospective Cohort Study Incorporating a Restricted Cubic Spline Regression Model.

Yamakawa K, Gando S, Ogura H, Umemura Y, Kabata D, Shintani A, Shiraishi A, Saitoh D, Fujishima S, Mayumi T, Kushimoto S, Abe T, Shiino Y, Nakada TA, Tarui T, Hifumi T, Otomo Y, Okamoto K, Kotani J, Sakamoto Y, Sasaki J, Shiraishi SI, Takuma K, Tsuruta R, Hagiwara A, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Fujimi S; Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis Trauma (FORECAST) Study Group.

Thromb Haemost. 2019 Aug 13. doi: 10.1055/s-0039-1693740. [Epub ahead of print]

PMID:
31408900
26.

Utilizing fourth-generation endocytoscopy and the 'enlarged nuclear sign' for in vivo diagnosis of early gastric cancer.

Abad MRA, Inoue H, Ikeda H, Manolakis A, Rodriguez de Santiago E, Sharma A, Fujiyoshi Y, Fukuda H, Sumi K, Onimaru M, Shimamura Y.

Endosc Int Open. 2019 Aug;7(8):E1002-E1007. doi: 10.1055/a-0957-2866. Epub 2019 Aug 8.

27.

Occipital Sinus Dural Arteriovenous Fistula Presenting with Cerebellar Hemorrhage.

Kawauchi T, Ikeda H, Miyakoshi A, Go K, Oichi Y, Sano N, Hayase M, Toda H.

World Neurosurg. 2019 Aug 7;131:116-119. doi: 10.1016/j.wneu.2019.07.231. [Epub ahead of print]

PMID:
31398518
28.

Development of Novel δ Opioid Receptor Inverse Agonists without a Basic Nitrogen Atom and Their Antitussive Effects in Mice.

Higashi E, Hirayama S, Nikaido J, Shibasaki M, Kono T, Honjo A, Ikeda H, Kamei J, Fujii H.

ACS Chem Neurosci. 2019 Sep 18;10(9):3939-3945. doi: 10.1021/acschemneuro.9b00368. Epub 2019 Aug 15.

PMID:
31397148
29.

Phylogeography of Pulsatilla cernua (Ranunculaceae), a grassland species, in Japan.

Takaishi A, Kozhevnikov AE, Kozhevnikova ZV, Ikeda H, Fujii N, Soejima A.

Ecol Evol. 2019 Jun 13;9(12):7262-7272. doi: 10.1002/ece3.5298. eCollection 2019 Jun.

30.

Mechanism of Action of Prethioviridamide, an Anticancer Ribosomally Synthesized and Post-Translationally Modified Peptide with a Polythioamide Structure.

Takase S, Kurokawa R, Kondoh Y, Honda K, Suzuki T, Kawahara T, Ikeda H, Dohmae N, Osada H, Shin-Ya K, Kushiro T, Yoshida M, Matsumoto K.

ACS Chem Biol. 2019 Aug 16;14(8):1819-1828. doi: 10.1021/acschembio.9b00410. Epub 2019 Jul 31.

PMID:
31365229
31.

Redox state of albumin affects its lipid mediator binding characteristics.

Kurano M, Yasukawa K, Ikeda H, Aoki J, Yatomi Y.

Free Radic Res. 2019 Aug;53(8):892-900. doi: 10.1080/10715762.2019.1641603. Epub 2019 Jul 30.

PMID:
31357898
32.

Demographics, Treatments, and Outcomes of Acute Respiratory Distress Syndrome: The Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis, and Trauma (Forecast) Study.

Fujishima S, Gando S, Saitoh D, Kushimoto S, Ogura H, Abe T, Shiraishi A, Mayumi T, Sasaki J, Kotani J, Takeyama N, Tsuruta R, Takuma K, Yamashita N, Shiraishi SI, Ikeda H, Shiino Y, Tarui T, Nakada TA, Hifumi T, Otomo Y, Okamoto K, Sakamoto Y, Hagiwara A, Masuno T, Ueyama M, Fujimi S, Yamakawa K, Umemura Y; JAAM FORECAST ARDS Study Group.

Shock. 2019 Jul 23. doi: 10.1097/SHK.0000000000001416. [Epub ahead of print]

PMID:
31348148
33.

Results of a prospective clinical trial JN-L-10 using image-defined risk factors to inform surgical decisions for children with low-risk neuroblastoma disease: A report from the Japan Children's Cancer Group Neuroblastoma Committee.

Iehara T, Yoneda A, Yokota I, Takahashi H, Teramukai S, Kamijyo T, Nakazawa A, Takimoto T, Kikuta A, Yagyu S, Ikeda H, Nakagawara A, Tajiri T; Japan Childhood Cancer Group Neuroblastoma Committee (JNBSG).

Pediatr Blood Cancer. 2019 Nov;66(11):e27914. doi: 10.1002/pbc.27914. Epub 2019 Jul 24.

PMID:
31342649
34.

Haemodynamic responses to simulated long working hours in different age groups.

Liu X, Ikeda H, Oyama F, Takahashi M.

Occup Environ Med. 2019 Oct;76(10):754-757. doi: 10.1136/oemed-2019-105915. Epub 2019 Jul 24.

PMID:
31340998
35.

Pressure-guided second-generation cryoballoon pulmonary vein isolation: Prospective comparison of the procedural and clinical outcomes with the conventional strategy.

Hasegawa K, Miyazaki S, Kaseno K, Hisazaki K, Amaya N, Miyahara K, Aiki T, Ishikawa E, Mukai M, Matsui A, Aoyama D, Shiomi Y, Tama N, Ikeda H, Fukuoka Y, Morishita T, Ishida K, Uzui H, Tada H.

J Cardiovasc Electrophysiol. 2019 Oct;30(10):1841-1847. doi: 10.1111/jce.14080. Epub 2019 Aug 4.

PMID:
31328311
36.

Identification of human herpes virus 1 encoded microRNAs in biopsy samples of lower esophageal sphincter muscle during peroral endoscopic myotomy for esophageal achalasia.

Ikebuchi Y, Kanda T, Ikeda H, Yoshida A, Sakaguchi T, Urabe S, Minami H, Nakao K, Kuwamoto S, Inoue H, Isomoto H.

Dig Endosc. 2019 Jul 20. doi: 10.1111/den.13491. [Epub ahead of print]

PMID:
31325192
37.

Impact of CYP2C19 phenotypes on clinical efficacy of stiripentol in Japanese patients with Dravet syndrome.

Yamamoto Y, Takahashi Y, Ikeda H, Imai K, Kagawa Y, Inoue Y.

Ther Drug Monit. 2019 Jul 15. doi: 10.1097/FTD.0000000000000676. [Epub ahead of print]

PMID:
31318844
38.

A Novel Non-invasive Method for Predicting Liver Fibrosis by Quantifying the Hepatic Vein Waveform.

Soroida Y, Nakatsuka T, Sato M, Nakagawa H, Tanaka M, Yamauchi N, Wake T, Nakagomi R, Kinoshita MN, Minami T, Uchino K, Enooku K, Asaoka Y, Tanaka Y, Endo M, Nakamura A, Kobayashi T, Kurihara M, Hikita H, Sato M, Gotoh H, Iwai T, Fukayama M, Ikeda H, Tateishi R, Yatomi Y, Koike K.

Ultrasound Med Biol. 2019 Sep;45(9):2363-2371. doi: 10.1016/j.ultrasmedbio.2019.05.028. Epub 2019 Jul 12.

PMID:
31303401
39.

[Adoptive therapy with TCR gene-modified T cells for hematological malignancies and solid tumors].

Ikeda H.

Rinsho Ketsueki. 2019;60(6):716-722. doi: 10.11406/rinketsu.60.716. Review. Japanese.

PMID:
31281165
40.

Efficacy and Safety of Tolvaptan in Patients More Than 90 Years Old With Acute Heart Failure.

Sato Y, Uzui H, Mukai M, Shiomi Y, Hasegawa K, Ikeda H, Tama N, Fukuoka Y, Morishita T, Ishida K, Kaseno K, Miyazaki S, Nakano A, Tada H.

J Cardiovasc Pharmacol Ther. 2019 Jul 7:1074248419861962. doi: 10.1177/1074248419861962. [Epub ahead of print]

PMID:
31280620
41.

Evaluation of 8-week glecaprevir/pibrentasvir treatment in direct-acting antiviral-naïve noncirrhotic HCV genotype 1 and 2infected patients in a real-world setting in Japan.

Ikeda H, Watanabe T, Atsukawa M, Toyoda H, Takaguchi K, Nakamuta M, Matsumoto N, Okuse C, Tada T, Tsutsui A, Yamashita N, Kondo C, Hayama K, Kato K, Itokawa N, Arai T, Shimada N, Asano T, Uojima H, Ogawa C, Mikami S, Ikegami T, Fukunishi S, Asai A, Iio E, Tsubota A, Hiraoka A, Nozaki A, Okubo H, Tachi Y, Moriya A, Oikawa T, Matsumoto Y, Tsuruoka S, Tani J, Kikuchi K, Iwakiri K, Tanaka Y, Kumada T.

J Viral Hepat. 2019 Nov;26(11):1266-1275. doi: 10.1111/jvh.13170. Epub 2019 Aug 9.

PMID:
31278795
42.

Epithelioid variant of gastrointestinal stromal tumor harboring PDGFRA mutation and MLH1 gene alteration: A case report.

Kobayashi M, Inaguma S, Raffeld M, Kato H, Suzuki S, Wakasugi T, Mitsui A, Kuwabara Y, Lasota J, Ikeda H, Miettinen M, Takahashi S.

Pathol Int. 2019 Sep;69(9):541-546. doi: 10.1111/pin.12830. Epub 2019 Jul 4.

PMID:
31273885
43.

[A Case of Histiocytoid Breast Carcinoma Accompanied by Multiple Axillary Lymph Node Metastases].

Terakawa H, Gabata R, Ishikawa S, Hirata M, Inokuchi M, Kawashima H, Miyashita T, Tajima H, Takamura H, Ninomiya I, Fushida S, Ohta T, Oyama T, Ikeda H.

Gan To Kagaku Ryoho. 2019 Jun;46(6):1049-1051. Japanese.

PMID:
31273173
44.

Breakage and Retrieval of an Aspiration Catheter Coil with a Stent Retriever During Mechanical Thrombectomy.

Otsuka R, Ikeda H, Tsujimoto Y, Kawauchi T, Torikoshi S, Sano N, Hayase M, Toda H.

World Neurosurg. 2019 Oct;130:54-58. doi: 10.1016/j.wneu.2019.06.175. Epub 2019 Jun 29.

PMID:
31265926
45.

Pneumothorax as an Adverse Event in Patients with Lung Metastasis of Soft Tissue Sarcoma under Eribulin Treatment.

Takada K, Murase K, Nakamura H, Hayasaka N, Arihara Y, Iyama S, Ikeda H, Emori M, Sugita S, Nakamura K, Miyanishi K, Kobune M, Kato J.

Intern Med. 2019 Oct 15;58(20):3009-3012. doi: 10.2169/internalmedicine.2790-19. Epub 2019 Jun 27.

46.

Effects of Sitagliptin on the Coronary Flow Reserve, Circulating Endothelial Progenitor Cells and Stromal Cell-derived Factor-1alpha.

Morishita T, Uzui H, Ikeda H, Amaya N, Kaseno K, Ishida K, Fukuoka Y, Tada H.

Intern Med. 2019 Oct 1;58(19):2773-2781. doi: 10.2169/internalmedicine.2616-19. Epub 2019 Jun 27.

47.

Clinical outcomes of per-oral endoscopic tumor resection for submucosal tumors in the esophagus and gastric cardia.

Onimaru M, Inoue H, Bechara R, Tanabe M, Abad MRA, Ueno A, Shimamura Y, Sumi K, Ikeda H, Ito H.

Dig Endosc. 2019 Jun 24. doi: 10.1111/den.13471. [Epub ahead of print]

PMID:
31234231
48.

[Construction of Management System Using Application Software for X-ray Protective Clothing Management].

Isobe A, Kogure Y, Ikeda H, Houshito H.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2019;75(6):546-552. doi: 10.6009/jjrt.2019_JSRT_75.6.546. Japanese.

49.

Diagnostic performance of the endoscopic pressure study integrated system (EPSIS): a novel diagnostic tool for gastroesophageal reflux disease.

Inoue H, Shimamura Y, Rodriguez de Santiago E, Kobayashi Y, Ominami M, Fujiyoshi Y, Sumi K, Ikeda H, Onimaru M, Manolakis AC.

Endoscopy. 2019 Aug;51(8):759-762. doi: 10.1055/a-0938-2777. Epub 2019 Jun 19.

PMID:
31216578
50.

Universal non-mean-field scaling in the density of states of amorphous solids.

Ikeda H.

Phys Rev E. 2019 May;99(5-1):050901. doi: 10.1103/PhysRevE.99.050901.

PMID:
31212547

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