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Items: 1 to 50 of 401

1.

Serial brain MRI changes related to autoimmune pathophysiology in Hashimoto encephalopathy with anti-NAE antibodies: A case-series study.

Matsunaga A, Ikawa M, Kawamura Y, Kishitani T, Yamamura O, Hamano T, Kimura H, Nakamoto Y, Yoneda M.

J Neurol Sci. 2019 Sep 7;406:116453. doi: 10.1016/j.jns.2019.116453. [Epub ahead of print]

PMID:
31525528
2.

Identification of multiple male reproductive tract-specific proteins that regulate sperm migration through the oviduct in mice.

Fujihara Y, Noda T, Kobayashi K, Oji A, Kobayashi S, Matsumura T, Larasati T, Oura S, Kojima-Kita K, Yu Z, Matzuk MM, Ikawa M.

Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18498-18506. doi: 10.1073/pnas.1908736116. Epub 2019 Aug 27.

3.

The testis-specific serine proteases Prss44, Prss46, and Prss54 are dispensable for mouse fertility.

Holcomb RJ, Oura S, Nozawa K, Kent K, Yu Z, Robertson MJ, Coarfa C, Matzuk MM, Ikawa M, Garcia TX.

Biol Reprod. 2019 Aug 12. pii: ioz158. doi: 10.1093/biolre/ioz158. [Epub ahead of print]

PMID:
31403672
4.

Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway.

Hayashi M, Machida T, Ishida Y, Ogata Y, Omori T, Takasumi M, Endo Y, Suzuki T, Sekimata M, Homma Y, Ikawa M, Ohira H, Fujita T, Sekine H.

J Immunol. 2019 Sep 15;203(6):1411-1416. doi: 10.4049/jimmunol.1900605. Epub 2019 Aug 9.

PMID:
31399515
5.

Physiological function of seminal vesicle secretions on male fecundity.

Noda T, Ikawa M.

Reprod Med Biol. 2019 Jun 17;18(3):241-246. doi: 10.1002/rmb2.12282. eCollection 2019 Jul. Review.

6.

Erratum: Publisher Correction: Calaxin is required for cilia-driven determination of vertebrate laterality.

Sasaki K, Shiba K, Nakamura A, Kawano N, Satouh Y, Yamaguchi H, Morikawa M, Shibata D, Yanase R, Jokura K, Nomura M, Miyado M, Takada S, Ueno H, Nonaka S, Baba T, Ikawa M, Kikkawa M, Miyado K, Inaba K.

Commun Biol. 2019 Jul 4;2:254. doi: 10.1038/s42003-019-0512-5. eCollection 2019.

7.

Calaxin is required for cilia-driven determination of vertebrate laterality.

Sasaki K, Shiba K, Nakamura A, Kawano N, Satouh Y, Yamaguchi H, Morikawa M, Shibata D, Yanase R, Jokura K, Nomura M, Miyado M, Takada S, Ueno H, Nonaka S, Baba T, Ikawa M, Kikkawa M, Miyado K, Inaba K.

Commun Biol. 2019 Jun 20;2:226. doi: 10.1038/s42003-019-0462-y. eCollection 2019. Erratum in: Commun Biol. 2019 Jul 4;2:254.

8.

CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice†.

Lu Y, Oura S, Matsumura T, Oji A, Sakurai N, Fujihara Y, Shimada K, Miyata H, Tobita T, Noda T, Castaneda JM, Kiyozumi D, Zhang Q, Larasati T, Young SAM, Kodani M, Huddleston CA, Robertson MJ, Coarfa C, Isotani A, Aitken RJ, Okabe M, Matzuk MM, Garcia TX, Ikawa M.

Biol Reprod. 2019 Aug 1;101(2):501-511. doi: 10.1093/biolre/ioz103.

9.

GPAT2 is required for piRNA biogenesis, transposon silencing, and maintenance of spermatogonia in mice†.

Shiromoto Y, Kuramochi-Miyagawa S, Nagamori I, Chuma S, Arakawa T, Nishimura T, Hasuwa H, Tachibana T, Ikawa M, Nakano T.

Biol Reprod. 2019 Jul 1;101(1):248-256. doi: 10.1093/biolre/ioz056.

PMID:
30951587
10.

Nine genes abundantly expressed in the epididymis are not essential for male fecundity in mice.

Noda T, Sakurai N, Nozawa K, Kobayashi S, Devlin DJ, Matzuk MM, Ikawa M.

Andrology. 2019 Sep;7(5):644-653. doi: 10.1111/andr.12621. Epub 2019 Mar 29.

PMID:
30927342
11.

Mice with Calr mutations homologous to human CALR mutations only exhibit mild thrombocytosis.

Shide K, Kameda T, Kamiunten A, Oji A, Ozono Y, Sekine M, Honda A, Kitanaka A, Akizuki K, Tahira Y, Nakamura K, Hidaka T, Kubuki Y, Abe H, Miike T, Iwakiri H, Tahara Y, Sueta M, Hasuike S, Yamamoto S, Nagata K, Ikawa M, Shimoda K.

Blood Cancer J. 2019 Mar 29;9(4):42. doi: 10.1038/s41408-019-0202-z.

12.

Cladophialophora bantiana infection mimicking neuromyelitis optica.

Enomoto S, Shigemi H, Kitazaki Y, Ikawa M, Yamamura O, Hamano T, Tai K, Iwasaki H, Koizumi H, Hasegawa M, Takeda K, Nakamoto Y.

J Neurol Sci. 2019 Apr 15;399:169-171. doi: 10.1016/j.jns.2018.12.013. Epub 2018 Dec 10.

PMID:
30822604
13.

Lvrn expression is not critical for mouse placentation.

Tobita T, Kiyozumi D, Muto M, Noda T, Ikawa M.

J Reprod Dev. 2019 Jun 14;65(3):239-244. doi: 10.1262/jrd.2018-157. Epub 2019 Feb 10.

14.

[Positron Emission Tomography Imaging for Oxidative Stress in Mitochondrial and Neurodegenerative Diseases].

Ikawa M, Okazawa H, Yoneda M.

Brain Nerve. 2019 Feb;71(2):161-166. doi: 10.11477/mf.1416201236. Japanese.

PMID:
30718445
15.

Glycerol kinase 2 is essential for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during mouse spermatogenesis.

Shimada K, Kato H, Miyata H, Ikawa M.

J Reprod Dev. 2019 Apr 12;65(2):155-162. doi: 10.1262/jrd.2018-136. Epub 2019 Jan 21.

16.

USP15 Participates in Hepatitis C Virus Propagation through Regulation of Viral RNA Translation and Lipid Droplet Formation.

Kusakabe S, Suzuki T, Sugiyama Y, Haga S, Horike K, Tokunaga M, Hirano J, Zhang H, Chen DV, Ishiga H, Komoda Y, Ono C, Fukuhara T, Yamamoto M, Ikawa M, Satoh T, Akira S, Tanaka T, Moriishi K, Fukai M, Taketomi A, Yoshio S, Kanto T, Suzuki T, Okamoto T, Matsuura Y.

J Virol. 2019 Mar 5;93(6). pii: e01708-18. doi: 10.1128/JVI.01708-18. Print 2019 Mar 15.

17.

An azoospermic factor gene, Ddx3y and its paralog, Ddx3x are dispensable in germ cells for male fertility.

Matsumura T, Endo T, Isotani A, Ogawa M, Ikawa M.

J Reprod Dev. 2019 Apr 12;65(2):121-128. doi: 10.1262/jrd.2018-145. Epub 2019 Jan 7.

18.

CKAP4, a DKK1 Receptor, Is a Biomarker in Exosomes Derived from Pancreatic Cancer and a Molecular Target for Therapy.

Kimura H, Yamamoto H, Harada T, Fumoto K, Osugi Y, Sada R, Maehara N, Hikita H, Mori S, Eguchi H, Ikawa M, Takehara T, Kikuchi A.

Clin Cancer Res. 2019 Mar 15;25(6):1936-1947. doi: 10.1158/1078-0432.CCR-18-2124. Epub 2019 Jan 4.

PMID:
30610103
19.

Impaired male fertility and abnormal epididymal epithelium differentiation in mice lacking CRISP1 and CRISP4.

Carvajal G, Brukman NG, Weigel Muñoz M, Battistone MA, Guazzone VA, Ikawa M, Haruhiko M, Lustig L, Breton S, Cuasnicu PS.

Sci Rep. 2018 Dec 3;8(1):17531. doi: 10.1038/s41598-018-35719-3.

20.

Laminin γ1 C-terminal Glu to Gln mutation induces early postimplantation lethality.

Kiyozumi D, Taniguchi Y, Nakano I, Toga J, Yagi E, Hasuwa H, Ikawa M, Sekiguchi K.

Life Sci Alliance. 2018 Sep 10;1(5):e201800064. doi: 10.26508/lsa.201800064. eCollection 2018 Oct.

21.

Seminal vesicle secretory protein 7, PATE4, is not required for sperm function but for copulatory plug formation to ensure fecundity†.

Noda T, Fujihara Y, Matsumura T, Oura S, Kobayashi S, Ikawa M.

Biol Reprod. 2019 Apr 1;100(4):1035-1045. doi: 10.1093/biolre/ioy247.

22.

PTBP1 contributes to spermatogenesis through regulation of proliferation in spermatogonia.

Senoo M, Takijiri T, Yoshida N, Ozawa M, Ikawa M.

J Reprod Dev. 2019 Feb 8;65(1):37-46. doi: 10.1262/jrd.2018-109. Epub 2018 Nov 12.

23.

Ventricular-subventricular zone fractones are speckled basement membranes that function as a neural stem cell niche.

Sato Y, Kiyozumi D, Futaki S, Nakano I, Shimono C, Kaneko N, Ikawa M, Okabe M, Sawamoto K, Sekiguchi K.

Mol Biol Cell. 2019 Jan 1;30(1):56-68. doi: 10.1091/mbc.E18-05-0286. Epub 2018 Oct 31.

24.

Introduction of integrated dental training jaw models and rubric criteria.

Tenkumo T, Fuji T, Ikawa M, Shoji S, Sasazaki H, Iwamatsu-Kobayashi Y, Okuyama Y, Matsui H, Shiraishi N, Furuuchi T, Higuchi K, Hashimoto W, Takeuchi Y, Simauchi H, Sasaki K.

Eur J Dent Educ. 2019 Feb;23(1):e17-e31. doi: 10.1111/eje.12395. Epub 2018 Oct 11.

PMID:
30306676
25.

Infection with flaviviruses requires BCLXL for cell survival.

Suzuki T, Okamoto T, Katoh H, Sugiyama Y, Kusakabe S, Tokunaga M, Hirano J, Miyata Y, Fukuhara T, Ikawa M, Satoh T, Yoshio S, Suzuki R, Saijo M, Huang DCS, Kanto T, Akira S, Matsuura Y.

PLoS Pathog. 2018 Sep 27;14(9):e1007299. doi: 10.1371/journal.ppat.1007299. eCollection 2018 Sep.

26.

mDia1/3 generate cortical F-actin meshwork in Sertoli cells that is continuous with contractile F-actin bundles and indispensable for spermatogenesis and male fertility.

Sakamoto S, Thumkeo D, Ohta H, Zhang Z, Huang S, Kanchanawong P, Fuu T, Watanabe S, Shimada K, Fujihara Y, Yoshida S, Ikawa M, Watanabe N, Saitou M, Narumiya S.

PLoS Biol. 2018 Sep 26;16(9):e2004874. doi: 10.1371/journal.pbio.2004874. eCollection 2018 Sep.

27.

Arterial spin labeling MR imaging for the clinical detection of cerebellar hypoperfusion in patients with spinocerebellar degeneration.

Ikawa M, Kimura H, Kitazaki Y, Sugimoto K, Matsunaga A, Hayashi K, Yamamura O, Tsujikawa T, Hamano T, Yoneda M, Okazawa H, Nakamoto Y.

J Neurol Sci. 2018 Nov 15;394:58-62. doi: 10.1016/j.jns.2018.09.007. Epub 2018 Sep 6.

PMID:
30216759
28.

Co-expression of sperm membrane proteins CMTM2A and CMTM2B is essential for ADAM3 localization and male fertility in mice.

Fujihara Y, Oji A, Kojima-Kita K, Larasati T, Ikawa M.

J Cell Sci. 2018 Oct 8;131(19). pii: jcs221481. doi: 10.1242/jcs.221481.

29.

RSPH6A is required for sperm flagellum formation and male fertility in mice.

Abbasi F, Miyata H, Shimada K, Morohoshi A, Nozawa K, Matsumura T, Xu Z, Pratiwi P, Ikawa M.

J Cell Sci. 2018 Oct 11;131(19). pii: jcs221648. doi: 10.1242/jcs.221648.

30.

New Insights into the Molecular Events of Mammalian Fertilization.

Satouh Y, Ikawa M.

Trends Biochem Sci. 2018 Oct;43(10):818-828. doi: 10.1016/j.tibs.2018.08.006. Epub 2018 Aug 28. Review.

PMID:
30170889
31.

Engineered CRISPR-Cas9 nuclease with expanded targeting space.

Nishimasu H, Shi X, Ishiguro S, Gao L, Hirano S, Okazaki S, Noda T, Abudayyeh OO, Gootenberg JS, Mori H, Oura S, Holmes B, Tanaka M, Seki M, Hirano H, Aburatani H, Ishitani R, Ikawa M, Yachie N, Zhang F, Nureki O.

Science. 2018 Sep 21;361(6408):1259-1262. doi: 10.1126/science.aas9129. Epub 2018 Aug 30.

32.

Trophoblast-Specific Conditional Atg7 Knockout Mice Develop Gestational Hypertension.

Aoki A, Nakashima A, Kusabiraki T, Ono Y, Yoshino O, Muto M, Kumasawa K, Yoshimori T, Ikawa M, Saito S.

Am J Pathol. 2018 Nov;188(11):2474-2486. doi: 10.1016/j.ajpath.2018.07.021. Epub 2018 Aug 27.

PMID:
30165042
33.

Chimeric analysis with newly established EGFP/DsRed2-tagged ES cells identify HYDIN as essential for spermiogenesis in mice.

Oura S, Miyata H, Noda T, Shimada K, Matsumura T, Morohoshi A, Isotani A, Ikawa M.

Exp Anim. 2019 Feb 26;68(1):25-34. doi: 10.1538/expanim.18-0071. Epub 2018 Aug 9.

34.

Response of brain-derived neurotrophic factor to combining cognitive and physical exercise.

Miyamoto T, Hashimoto S, Yanamoto H, Ikawa M, Nakano Y, Sekiyama T, Kou K, Kashiwamura SI, Takeda C, Fujioka H.

Eur J Sport Sci. 2018 Sep;18(8):1119-1127. doi: 10.1080/17461391.2018.1470676. Epub 2018 May 29.

PMID:
29842831
35.

3-Substituted 1,5-Diaryl-1 H-1,2,4-triazoles as Prospective PET Radioligands for Imaging Brain COX-1 in Monkey. Part 2: Selection and Evaluation of [11C]PS13 for Quantitative Imaging.

Shrestha S, Singh P, Cortes-Salva MY, Jenko KJ, Ikawa M, Kim MJ, Kobayashi M, Morse CL, Gladding RL, Liow JS, Zoghbi SS, Fujita M, Innis RB, Pike VW.

ACS Chem Neurosci. 2018 Nov 21;9(11):2620-2627. doi: 10.1021/acschemneuro.8b00103. Epub 2018 Jun 13.

36.

Two Ck1δ transcripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock.

Fustin JM, Kojima R, Itoh K, Chang HY, Ye S, Zhuang B, Oji A, Gibo S, Narasimamurthy R, Virshup D, Kurosawa G, Doi M, Manabe I, Ishihama Y, Ikawa M, Okamura H.

Proc Natl Acad Sci U S A. 2018 Jun 5;115(23):5980-5985. doi: 10.1073/pnas.1721371115. Epub 2018 May 21. Erratum in: Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):E6386.

37.

MARCKSL1 Regulates Spine Formation in the Amygdala and Controls the Hypothalamic-Pituitary-Adrenal Axis and Anxiety-Like Behaviors.

Tanaka T, Shimizu S, Ueno M, Fujihara Y, Ikawa M, Miyata S.

EBioMedicine. 2018 Apr;30:62-73. doi: 10.1016/j.ebiom.2018.03.018. Epub 2018 Mar 19.

38.

Homocysteine Increases Tau Phosphorylation, Truncation and Oligomerization.

Shirafuji N, Hamano T, Yen SH, Kanaan NM, Yoshida H, Hayashi K, Ikawa M, Yamamura O, Kuriyama M, Nakamoto Y.

Int J Mol Sci. 2018 Mar 17;19(3). pii: E891. doi: 10.3390/ijms19030891.

39.

Intravesicular Acidification Regulates Lipopolysaccharide Inflammation and Tolerance through TLR4 Trafficking.

Murase M, Kawasaki T, Hakozaki R, Sueyoshi T, Putri DDP, Kitai Y, Sato S, Ikawa M, Kawai T.

J Immunol. 2018 Apr 15;200(8):2798-2808. doi: 10.4049/jimmunol.1701390. Epub 2018 Mar 14.

40.

Tropomyosin 2 heterozygous knockout in mice using CRISPR-Cas9 system displays the inhibition of injury-induced epithelial-mesenchymal transition, and lens opacity.

Shibata T, Shibata S, Ishigaki Y, Kiyokawa E, Ikawa M, Singh DP, Sasaki H, Kubo E.

Mech Ageing Dev. 2018 Apr;171:24-30. doi: 10.1016/j.mad.2018.03.001. Epub 2018 Mar 3.

41.

Transgenic mouse lines expressing the 3xFLAG-dCas9 protein for enChIP analysis.

Fujita T, Kitaura F, Oji A, Tanigawa N, Yuno M, Ikawa M, Taniuchi I, Fujii H.

Genes Cells. 2018 Apr;23(4):318-325. doi: 10.1111/gtc.12573. Epub 2018 Feb 26.

42.

Revolutionizing male fertility factor research in mice by using the genome editing tool CRISPR/Cas9.

Abbasi F, Miyata H, Ikawa M.

Reprod Med Biol. 2017 Oct 14;17(1):3-10. doi: 10.1002/rmb2.12067. eCollection 2018 Jan. Review.

43.

Sperm-borne phospholipase C zeta-1 ensures monospermic fertilization in mice.

Nozawa K, Satouh Y, Fujimoto T, Oji A, Ikawa M.

Sci Rep. 2018 Jan 22;8(1):1315. doi: 10.1038/s41598-018-19497-6.

44.

Factors controlling sperm migration through the oviduct revealed by gene-modified mouse models.

Fujihara Y, Miyata H, Ikawa M.

Exp Anim. 2018 May 10;67(2):91-104. doi: 10.1538/expanim.17-0153. Epub 2018 Jan 22. Review.

45.

Effect of Neuromuscular Electrical Stimulation on Brain-derived Neurotrophic Factor.

Miyamoto T, Kou K, Yanamoto H, Hashimoto S, Ikawa M, Sekiyama T, Nakano Y, Kashiwamura SI, Takeda C, Fujioka H.

Int J Sports Med. 2018 Jan;39(1):5-11. doi: 10.1055/s-0043-120343. Epub 2017 Nov 10.

PMID:
29126338
46.

Modification of single-nucleotide polymorphism in a fully humanized CYP3A mouse by genome editing technology.

Abe S, Kobayashi K, Oji A, Sakuma T, Kazuki K, Takehara S, Nakamura K, Okada A, Tsukazaki Y, Senda N, Honma K, Yamamoto T, Ikawa M, Chiba K, Oshimura M, Kazuki Y.

Sci Rep. 2017 Nov 9;7(1):15189. doi: 10.1038/s41598-017-15033-0.

47.

Human Globozoospermia-Related Gene Spata16 Is Required for Sperm Formation Revealed by CRISPR/Cas9-Mediated Mouse Models.

Fujihara Y, Oji A, Larasati T, Kojima-Kita K, Ikawa M.

Int J Mol Sci. 2017 Oct 21;18(10). pii: E2208. doi: 10.3390/ijms18102208.

48.

Comparison of four 11C-labeled PET ligands to quantify translocator protein 18 kDa (TSPO) in human brain: (R)-PK11195, PBR28, DPA-713, and ER176-based on recent publications that measured specific-to-non-displaceable ratios.

Fujita M, Kobayashi M, Ikawa M, Gunn RN, Rabiner EA, Owen DR, Zoghbi SS, Haskali MB, Telu S, Pike VW, Innis RB.

EJNMMI Res. 2017 Oct 16;7(1):84. doi: 10.1186/s13550-017-0334-8.

49.

Mouse spermatozoa with higher fertilization rates have thinner nuclei.

Mashiko D, Ikawa M, Fujimoto K.

PeerJ. 2017 Oct 12;5:e3913. doi: 10.7717/peerj.3913. eCollection 2017.

50.

Placenta-specific gene manipulation using lentiviral vector and its application.

Tobita T, Kiyozumi D, Ikawa M.

Placenta. 2017 Nov;59 Suppl 1:S37-S43. doi: 10.1016/j.placenta.2017.09.012. Epub 2017 Sep 28. Review.

PMID:
28988726

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