Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 150

1.

Flavonol glycosides of Rosa multiflora regulates intestinal barrier function through inhibiting claudin expression in differentiated Caco-2 cells.

Endo S, Matsuoka T, Nishiyama T, Arai Y, Kashiwagi H, Abe N, Oyama M, Matsunaga T, Ikari A.

Nutr Res. 2019 Nov 4. pii: S0271-5317(19)30519-6. doi: 10.1016/j.nutres.2019.10.010. [Epub ahead of print]

PMID:
31767206
2.

Pathophysiological roles of autophagy and aldo-keto reductases in development of doxorubicin resistance in gastrointestinal cancer cells.

Matsunaga T, Kawabata S, Yanagihara Y, Kezuka C, Kato M, Morikawa Y, Endo S, Chen H, Iguchi K, Ikari A.

Chem Biol Interact. 2019 Dec 1;314:108839. doi: 10.1016/j.cbi.2019.108839. Epub 2019 Sep 26.

PMID:
31563593
3.

Chrysin enhances anticancer drug-induced toxicity mediated by the reduction of claudin-1 and 11 expression in a spheroid culture model of lung squamous cell carcinoma cells.

Maruhashi R, Eguchi H, Akizuki R, Hamada S, Furuta T, Matsunaga T, Endo S, Ichihara K, Ikari A.

Sci Rep. 2019 Sep 24;9(1):13753. doi: 10.1038/s41598-019-50276-z.

4.

Brazilian Green Propolis Rescues Oxidative Stress-Induced Mislocalization of Claudin-1 in Human Keratinocyte-Derived HaCaT Cells.

Marunaka K, Kobayashi M, Shu S, Matsunaga T, Ikari A.

Int J Mol Sci. 2019 Aug 8;20(16). pii: E3869. doi: 10.3390/ijms20163869.

5.

Rescue of tight junctional localization of a claudin-16 mutant D97S by antimalarial medicine primaquine in Madin-Darby canine kidney cells.

Marunaka K, Fujii N, Kimura T, Furuta T, Hasegawa H, Matsunaga T, Endo S, Ikari A.

Sci Rep. 2019 Jul 4;9(1):9647. doi: 10.1038/s41598-019-46250-4.

6.

De-escalated neoadjuvant therapy with nanoparticle albumin-bound paclitaxel and trastuzumab for low-risk pure HER2 breast cancer.

Tanaka S, Matsunami N, Morishima H, Oda N, Takashima T, Noda S, Kashiwagi S, Tauchi Y, Asano Y, Kimura K, Fujioka H, Terasawa R, Kawaguchi K, Ikari A, Morimoto T, Michishita S, Kobayashi T, Sakane J, Nitta T, Sato N, Hokimoto N, Nishida Y, Iwamoto M.

Cancer Chemother Pharmacol. 2019 Jun;83(6):1099-1104. doi: 10.1007/s00280-019-03836-z. Epub 2019 Apr 8.

PMID:
30963212
7.

Rabbit dehydrogenase/reductase SDR family member 11 (DHRS11): Its identity with acetohexamide reductase with broad substrate specificity and inhibitor sensitivity, different from human DHRS11.

Endo S, Miyagi N, Matsunaga T, Ikari A.

Chem Biol Interact. 2019 May 25;305:12-20. doi: 10.1016/j.cbi.2019.03.026. Epub 2019 Mar 26.

PMID:
30926317
8.

Cyanidin Increases the Expression of Mg2+ Transport Carriers Mediated by the Activation of PPARα in Colonic Epithelial MCE301 Cells.

Takashina Y, Manabe A, Tabuchi Y, Ikari A.

Nutrients. 2019 Mar 16;11(3). pii: E641. doi: 10.3390/nu11030641.

9.

ZO-2 Suppresses Cell Migration Mediated by a Reduction in Matrix Metalloproteinase 2 in Claudin-18-Expressing Lung Adenocarcinoma A549 Cells.

Akizuki R, Eguchi H, Endo S, Matsunaga T, Ikari A.

Biol Pharm Bull. 2019;42(2):247-254. doi: 10.1248/bpb.b18-00670.

10.

Caffeic acid phenethyl ester potentiates gastric cancer cell sensitivity to doxorubicin and cisplatin by decreasing proteasome function.

Matsunaga T, Tsuchimura S, Azuma N, Endo S, Ichihara K, Ikari A.

Anticancer Drugs. 2019 Mar;30(3):251-259. doi: 10.1097/CAD.0000000000000715.

PMID:
30489290
11.

Upregulation of transient receptor potential melastatin 6 channel expression by rosiglitazone and all-trans-retinoic acid in erlotinib-treated renal tubular epithelial cells.

Manabe A, Furukawa C, Hasegawa H, Matsunaga T, Endo S, Ikari A.

J Cell Physiol. 2019 Jun;234(6):8951-8962. doi: 10.1002/jcp.27565. Epub 2018 Nov 21.

PMID:
30461012
12.

Sibutramine facilitates apoptosis and contraction of aortic smooth muscle cells through elevating production of reactive oxygen species.

Morikawa Y, Shibata A, Sasajima Y, Suenami K, Sato K, Takekoshi Y, Endo S, Ikari A, Matsunaga T.

Eur J Pharmacol. 2018 Dec 15;841:113-121. doi: 10.1016/j.ejphar.2018.10.009. Epub 2018 Oct 16.

PMID:
30339816
13.

Increase in resistance to anticancer drugs involves occludin in spheroid culture model of lung adenocarcinoma A549 cells.

Eguchi H, Akizuki R, Maruhashi R, Tsukimoto M, Furuta T, Matsunaga T, Endo S, Ikari A.

Sci Rep. 2018 Oct 11;8(1):15157. doi: 10.1038/s41598-018-33566-w.

14.

Crosstalk between Na+,K+-ATPase and a volume-regulated anion channel in membrane microdomains of human cancer cells.

Fujii T, Shimizu T, Yamamoto S, Funayama K, Fujita K, Tabuchi Y, Ikari A, Takeshima H, Sakai H.

Biochim Biophys Acta Mol Basis Dis. 2018 Nov;1864(11):3792-3804. doi: 10.1016/j.bbadis.2018.09.014. Epub 2018 Sep 13.

15.

Sodium Citrate Increases Expression and Flux of Mg2+ Transport Carriers Mediated by Activation of MEK/ERK/c-Fos Pathway in Renal Tubular Epithelial Cells.

Takashina Y, Manabe A, Hasegawa H, Matsunaga T, Endo S, Ikari A.

Nutrients. 2018 Sep 20;10(10). pii: E1345. doi: 10.3390/nu10101345.

16.

Luminal Na+ homeostasis has an important role in intestinal peptide absorption in vivo.

Ishizuka N, Nakayama M, Watanabe M, Tajima H, Yamauchi Y, Ikari A, Hayashi H.

Am J Physiol Gastrointest Liver Physiol. 2018 Nov 1;315(5):G799-G809. doi: 10.1152/ajpgi.00099.2018. Epub 2018 Aug 23.

17.

Down-regulation of magnesium transporting molecule, claudin-16, as a possible cause of hypermagnesiuria with the development of tubulo-interstitial nephropathy.

Shimizu T, Takayanagi K, Iwashita T, Ikari A, Anzai N, Okazaki S, Hara H, Hatano M, Sano T, Ogawa T, Kanozawa K, Hasegawa H.

Magnes Res. 2018 Feb 1;31(1):11-23. doi: 10.1684/mrh.2018.0434.

PMID:
29991461
18.

Caffeic acid phenethyl ester down-regulates claudin-2 expression at the transcriptional and post-translational levels and enhances chemosensitivity to doxorubicin in lung adenocarcinoma A549 cells.

Sonoki H, Tanimae A, Furuta T, Endo S, Matsunaga T, Ichihara K, Ikari A.

J Nutr Biochem. 2018 Jun;56:205-214. doi: 10.1016/j.jnutbio.2018.02.016. Epub 2018 Mar 2.

PMID:
29597147
19.

Decrease in paracellular permeability and chemosensitivity to doxorubicin by claudin-1 in spheroid culture models of human lung adenocarcinoma A549 cells.

Akizuki R, Maruhashi R, Eguchi H, Kitabatake K, Tsukimoto M, Furuta T, Matsunaga T, Endo S, Ikari A.

Biochim Biophys Acta Mol Cell Res. 2018 May;1865(5):769-780. doi: 10.1016/j.bbamcr.2018.03.001. Epub 2018 Mar 7.

20.

Autophagy inhibition enhances anticancer efficacy of artepillin C, a cinnamic acid derivative in Brazilian green propolis.

Endo S, Hoshi M, Matsunaga T, Inoue T, Ichihara K, Ikari A.

Biochem Biophys Res Commun. 2018 Feb 26;497(1):437-443. doi: 10.1016/j.bbrc.2018.02.105. Epub 2018 Feb 13.

PMID:
29452093
21.

Photoinduced Generation of Acyl Radicals from Simple Aldehydes, Access to 3-Acyl-4-arylcoumarin Derivatives, and Evaluation of Their Antiandrogenic Activities.

Kawaai K, Yamaguchi T, Yamaguchi E, Endo S, Tada N, Ikari A, Itoh A.

J Org Chem. 2018 Feb 16;83(4):1988-1996. doi: 10.1021/acs.joc.7b02933. Epub 2018 Jan 30.

PMID:
29327585
22.

Correction to Synthesis of Potent and Selective Inhibitors of Aldo-Keto Reductase 1B10 and Their Efficacy against Proliferation, Metastasis, and Cisplatin Resistance of Lung Cancer Cells.

Endo S, Xia S, Suyama M, Morikawa Y, Oguri H, Hu D, Ao Y, Takahara S, Horino Y, Hayakawa Y, Watanabe Y, Gouda H, Hara A, Kuwata K, Toyooka N, Matsunaga T, Ikari A.

J Med Chem. 2018 Feb 8;61(3):1380. doi: 10.1021/acs.jmedchem.7b01911. Epub 2018 Jan 11. No abstract available.

PMID:
29323483
23.

Elevation of sensitivity to anticancer agents of human lung adenocarcinoma A549 cells by knockdown of claudin-2 expression in monolayer and spheroid culture models.

Maruhashi R, Akizuki R, Sato T, Matsunaga T, Endo S, Yamaguchi M, Yamazaki Y, Sakai H, Ikari A.

Biochim Biophys Acta Mol Cell Res. 2018 Mar;1865(3):470-479. doi: 10.1016/j.bbamcr.2017.12.005. Epub 2017 Dec 13.

24.

Facilitation of 9,10-phenanthrenequinone-elicited neuroblastoma cell apoptosis by NAD(P)H:quinone oxidoreductase 1.

Matsunaga T, Kamase K, Takasawa H, Yamaji Y, Endo S, El-Kabbani O, Ikari A.

Chem Biol Interact. 2018 Jan 5;279:10-20. doi: 10.1016/j.cbi.2017.10.028. Epub 2017 Nov 10.

PMID:
29108775
25.

Synthesis of Potent and Selective Inhibitors of Aldo-Keto Reductase 1B10 and Their Efficacy against Proliferation, Metastasis, and Cisplatin Resistance of Lung Cancer Cells.

Endo S, Xia S, Suyama M, Morikawa Y, Oguri H, Hu D, Ao Y, Takahara S, Horino Y, Hayakawa Y, Watanabe Y, Gouda H, Hara A, Kuwata K, Toyooka N, Matsunaga T, Ikari A.

J Med Chem. 2017 Oct 26;60(20):8441-8455. doi: 10.1021/acs.jmedchem.7b00830. Epub 2017 Oct 13. Erratum in: J Med Chem. 2018 Feb 8;61(3):1380.

PMID:
28976752
26.

Enhancement of Endothelial Barrier Permeability by Mitragynine.

Matsunaga T, Morikawa Y, Kamase K, Horinouchi M, Sasajima Y, Suenami K, Sato K, Takekoshi Y, Endo S, El-Kabbani O, Ikari A.

Biol Pharm Bull. 2017;40(10):1779-1783. doi: 10.1248/bpb.b17-00117.

27.

Up-regulation of claudin-2 expression by aldosterone in colonic epithelial cells of mice fed with NaCl-depleted diets.

Furukawa C, Ishizuka N, Hayashi H, Fujii N, Manabe A, Tabuchi Y, Matsunaga T, Endo S, Ikari A.

Sci Rep. 2017 Sep 22;7(1):12223. doi: 10.1038/s41598-017-12494-1.

28.

Chlorpheniramine Increases Paracellular Permeability to Marker Fluorescein Lucifer Yellow Mediated by Internalization of Occludin in Murine Colonic Epithelial Cells.

Manabe A, Furukawa C, Endo S, Marunaka K, Nishiyama T, Fujii N, Tabuchi Y, Matsunaga T, Ikari A.

Biol Pharm Bull. 2017;40(8):1299-1305. doi: 10.1248/bpb.b17-00244.

29.

Long-term irreversible trastuzumab-induced cardiotoxicity for metastatic breast cancer in a patient without cardiac risk factors.

Tanaka S, Ikari A, Nitta T, Horiuchi T.

Oxf Med Case Reports. 2017 Jul 6;2017(7):omx038. doi: 10.1093/omcr/omx038. eCollection 2017 Jul.

30.

The RING finger- and PDZ domain-containing protein PDZRN3 controls localization of the Mg2+ regulator claudin-16 in renal tube epithelial cells.

Marunaka K, Furukawa C, Fujii N, Kimura T, Furuta T, Matsunaga T, Endo S, Hasegawa H, Anzai N, Yamazaki Y, Yamaguchi M, Ikari A.

J Biol Chem. 2017 Aug 4;292(31):13034-13044. doi: 10.1074/jbc.M117.779405. Epub 2017 Jun 16.

31.

Kaempherol and Luteolin Decrease Claudin-2 Expression Mediated by Inhibition of STAT3 in Lung Adenocarcinoma A549 Cells.

Sonoki H, Tanimae A, Endo S, Matsunaga T, Furuta T, Ichihara K, Ikari A.

Nutrients. 2017 Jun 13;9(6). pii: E597. doi: 10.3390/nu9060597.

32.

α-Pyrrolidinononanophenone provokes apoptosis of neuronal cells through alterations in antioxidant properties.

Matsunaga T, Morikawa Y, Kamata K, Shibata A, Miyazono H, Sasajima Y, Suenami K, Sato K, Takekoshi Y, Endo S, El-Kabbani O, Ikari A.

Toxicology. 2017 Jul 1;386:93-102. doi: 10.1016/j.tox.2017.05.017. Epub 2017 May 31.

PMID:
28578026
33.

Elongation of barley roots in high-pH nutrient solution is supported by both cell proliferation and differentiation in the root apex.

Higuchi K, Ono K, Araki S, Nakamura S, Uesugi T, Makishima T, Ikari A, Hanaoka T, Sue M.

Plant Cell Environ. 2017 Aug;40(8):1609-1617. doi: 10.1111/pce.12969. Epub 2017 May 26.

PMID:
28425570
34.

Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells.

Hichino A, Okamoto M, Taga S, Akizuki R, Endo S, Matsunaga T, Ikari A.

J Biol Chem. 2017 Feb 10;292(6):2411-2421. doi: 10.1074/jbc.M116.762807. Epub 2017 Jan 5.

35.

[Maintenance of Long-Term Stable Disease(SD)in Metastatic Breast Cancer with Eribulin - A Case Report of Long-Term SD in Japan].

Nitta T, Kimura K, Tominaga T, Fujii K, Sato N, Ikari A, Miyoshi K, Tanaka S, Ishibashi T, Iwamoto M.

Gan To Kagaku Ryoho. 2016 Dec;43(13):2543-2546. Review. Japanese.

PMID:
28028262
36.

Instability of C154Y variant of aldo-keto reductase 1C3.

Endo S, Takada S, Honda RP, Müller K, Weishaupt JH, Andersen PM, Ludolph AC, Kamatari YO, Matsunaga T, Kuwata K, El-Kabbani O, Ikari A.

Chem Biol Interact. 2017 Oct 1;276:194-202. doi: 10.1016/j.cbi.2016.12.018. Epub 2016 Dec 23.

PMID:
28025170
37.

Up-Regulation of Transient Receptor Potential Melastatin 6 Channel Expression by Tumor Necrosis Factor-α in the Presence of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor.

Furukawa C, Fujii N, Manabe A, Matsunaga T, Endo S, Hasegawa H, Ito Y, Yamaguchi M, Yamazaki Y, Ikari A.

J Cell Physiol. 2017 Oct;232(10):2841-2850. doi: 10.1002/jcp.25709. Epub 2017 Apr 25.

PMID:
27925186
38.

A Phase II Study of Adjuvant Chemotherapy of Tegafur-Uracil for Patients with Breast Cancer with HER2-negative Pathologic Residual Invasive Disease After Neoadjuvant Chemotherapy.

Tanaka S, Iwamoto M, Kimura K, Takahashi Y, Fujioka H, Sato N, Terasawa R, Kawaguchi K, Ikari A, Tominaga T, Maezawa S, Umezaki N, Matsuda J, Uchiyama K.

Anticancer Res. 2016 Dec;36(12):6505-6509.

PMID:
27919974
39.

Claudin-5, -7, and -18 suppress proliferation mediated by inhibition of phosphorylation of Akt in human lung squamous cell carcinoma.

Akizuki R, Shimobaba S, Matsunaga T, Endo S, Ikari A.

Biochim Biophys Acta Mol Cell Res. 2017 Feb;1864(2):293-302. doi: 10.1016/j.bbamcr.2016.11.018. Epub 2016 Nov 21.

40.

Sibutramine provokes apoptosis of aortic endothelial cells through altered production of reactive oxygen and nitrogen species.

Morikawa Y, Shibata A, Okumura N, Ikari A, Sasajima Y, Suenami K, Sato K, Takekoshi Y, El-Kabbani O, Matsunaga T.

Toxicol Appl Pharmacol. 2017 Jan 1;314:1-11. doi: 10.1016/j.taap.2016.11.003. Epub 2016 Nov 9.

PMID:
27838152
41.

Hypotonic Stress-induced Down-regulation of Claudin-1 and -2 Mediated by Dephosphorylation and Clathrin-dependent Endocytosis in Renal Tubular Epithelial Cells.

Fujii N, Matsuo Y, Matsunaga T, Endo S, Sakai H, Yamaguchi M, Yamazaki Y, Sugatani J, Ikari A.

J Biol Chem. 2016 Nov 18;291(47):24787-24799. Epub 2016 Oct 12.

42.

Roles of aldo-keto reductases 1B10 and 1C3 and ATP-binding cassette transporter in docetaxel tolerance.

Matsunaga T, Saito H, Endo S, Iguchi K, Soda M, El-Kabbani O, Hara A, Ikari A.

Free Radic Res. 2016 Dec;50(12):1296-1308. Epub 2016 Oct 11.

PMID:
27629782
43.

Aldo-keto reductase 1B10 promotes development of cisplatin resistance in gastrointestinal cancer cells through down-regulating peroxisome proliferator-activated receptor-γ-dependent mechanism.

Matsunaga T, Suzuki A, Kezuka C, Okumura N, Iguchi K, Inoue I, Soda M, Endo S, El-Kabbani O, Hara A, Ikari A.

Chem Biol Interact. 2016 Aug 25;256:142-53. doi: 10.1016/j.cbi.2016.07.008. Epub 2016 Jul 11.

PMID:
27417252
44.

[A Case of Squamous Cell Carcinoma of the Breast].

Terasawa R, Iwamoto M, Tanaka S, Kimura K, Takahashi Y, Fujioka H, Sato N, Kawaguchi K, Ikari A, Maezawa S, Tominaga T, Matsuda J, Umezaki N, Uchiyama K.

Gan To Kagaku Ryoho. 2016 Jun;43(6):749-52. Japanese.

PMID:
27306813
45.

Human dehydrogenase/reductase (SDR family) member 11 is a novel type of 17β-hydroxysteroid dehydrogenase.

Endo S, Miyagi N, Matsunaga T, Hara A, Ikari A.

Biochem Biophys Res Commun. 2016 Mar 25;472(1):231-6. doi: 10.1016/j.bbrc.2016.01.190. Epub 2016 Feb 23.

PMID:
26920053
46.

Claudin-18 inhibits cell proliferation and motility mediated by inhibition of phosphorylation of PDK1 and Akt in human lung adenocarcinoma A549 cells.

Shimobaba S, Taga S, Akizuki R, Hichino A, Endo S, Matsunaga T, Watanabe R, Yamaguchi M, Yamazaki Y, Sugatani J, Ikari A.

Biochim Biophys Acta. 2016 Jun;1863(6 Pt A):1170-8. doi: 10.1016/j.bbamcr.2016.02.015. Epub 2016 Feb 24.

47.

Threonine-408 Regulates the Stability of Human Pregnane X Receptor through Its Phosphorylation and the CHIP/Chaperone-Autophagy Pathway.

Sugatani J, Noguchi Y, Hattori Y, Yamaguchi M, Yamazaki Y, Ikari A.

Drug Metab Dispos. 2016 Jan;44(1):137-50. doi: 10.1124/dmd.115.066308. Epub 2015 Nov 3.

PMID:
26534988
48.

Up-Regulation of Carbonyl Reductase 1 Renders Development of Doxorubicin Resistance in Human Gastrointestinal Cancers.

Matsunaga T, Kezuka C, Morikawa Y, Suzuki A, Endo S, Iguchi K, Miura T, Nishinaka T, Terada T, El-Kabbani O, Hara A, Ikari A.

Biol Pharm Bull. 2015;38(9):1309-19. doi: 10.1248/bpb.b15-00176.

49.

Clathrin-dependent endocytosis of claudin-2 by DFYSP peptide causes lysosomal damage in lung adenocarcinoma A549 cells.

Ikari A, Taga S, Watanabe R, Sato T, Shimobaba S, Sonoki H, Endo S, Matsunaga T, Sakai H, Yamaguchi M, Yamazaki Y, Sugatani J.

Biochim Biophys Acta. 2015 Oct;1848(10 Pt A):2326-36. doi: 10.1016/j.bbamem.2015.07.003. Epub 2015 Jul 8.

50.

Synthesis of 8-hydroxy-2-iminochromene derivatives as selective and potent inhibitors of human carbonyl reductase 1.

Hu D, Miyagi N, Arai Y, Oguri H, Miura T, Nishinaka T, Terada T, Gouda H, El-Kabbani O, Xia S, Toyooka N, Hara A, Matsunaga T, Ikari A, Endo S.

Org Biomol Chem. 2015 Jul 21;13(27):7487-99. doi: 10.1039/c5ob00847f. Epub 2015 Jun 12.

PMID:
26068795

Supplemental Content

Support Center