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Items: 18


Reactive astrocytes promote the metastatic growth of breast cancer stem-like cells by activating Notch signalling in brain.

Xing F, Kobayashi A, Okuda H, Watabe M, Pai SK, Pandey PR, Hirota S, Wilber A, Mo YY, Moore BE, Liu W, Fukuda K, Iiizumi M, Sharma S, Liu Y, Wu K, Peralta E, Watabe K.

EMBO Mol Med. 2013 Mar;5(3):384-96. doi: 10.1002/emmm.201201623.


Cacalol, a natural sesquiterpene, induces apoptosis in breast cancer cells by modulating Akt-SREBP-FAS signaling pathway.

Liu W, Furuta E, Shindo K, Watabe M, Xing F, Pandey PR, Okuda H, Pai SK, Murphy LL, Cao D, Mo YY, Kobayashi A, Iiizumi M, Fukuda K, Xia B, Watabe K.

Breast Cancer Res Treat. 2011 Jul;128(1):57-68. doi: 10.1007/s10549-010-1076-8. Epub 2010 Jul 28.


RhoC promotes metastasis via activation of the Pyk2 pathway in prostate cancer.

Iiizumi M, Bandyopadhyay S, Pai SK, Watabe M, Hirota S, Hosobe S, Tsukada T, Miura K, Saito K, Furuta E, Liu W, Xing F, Okuda H, Kobayashi A, Watabe K.

Cancer Res. 2008 Sep 15;68(18):7613-20. doi: 10.1158/0008-5472.CAN-07-6700.


Drug development against metastasis-related genes and their pathways: a rationale for cancer therapy.

Iiizumi M, Liu W, Pai SK, Furuta E, Watabe K.

Biochim Biophys Acta. 2008 Dec;1786(2):87-104. doi: 10.1016/j.bbcan.2008.07.002. Epub 2008 Jul 22. Review.


Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1.

Furuta E, Pai SK, Zhan R, Bandyopadhyay S, Watabe M, Mo YY, Hirota S, Hosobe S, Tsukada T, Miura K, Kamada S, Saito K, Iiizumi M, Liu W, Ericsson J, Watabe K.

Cancer Res. 2008 Feb 15;68(4):1003-11. doi: 10.1158/0008-5472.CAN-07-2489.


Tumor-endothelial cell interactions: therapeutic potential.

Iiizumi M, Mohinta S, Bandyopadhyay S, Watabe K.

Microvasc Res. 2007 Sep-Nov;74(2-3):114-20. Epub 2007 Apr 14. Review.


Interaction of Duffy antigen receptor for chemokines and KAI1: a critical step in metastasis suppression.

Iiizumi M, Bandyopadhyay S, Watabe K.

Cancer Res. 2007 Feb 15;67(4):1411-4.


The tumor metastasis suppressor gene Drg-1 down-regulates the expression of activating transcription factor 3 in prostate cancer.

Bandyopadhyay S, Wang Y, Zhan R, Pai SK, Watabe M, Iiizumi M, Furuta E, Mohinta S, Liu W, Hirota S, Hosobe S, Tsukada T, Miura K, Takano Y, Saito K, Commes T, Piquemal D, Hai T, Watabe K.

Cancer Res. 2006 Dec 15;66(24):11983-90.


EphA4 receptor, overexpressed in pancreatic ductal adenocarcinoma, promotes cancer cell growth.

Iiizumi M, Hosokawa M, Takehara A, Chung S, Nakamura T, Katagiri T, Eguchi H, Ohigashi H, Ishikawa O, Nakamura Y, Nakagawa H.

Cancer Sci. 2006 Nov;97(11):1211-6. Epub 2006 Sep 5.


Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression.

Bandyopadhyay S, Zhan R, Chaudhuri A, Watabe M, Pai SK, Hirota S, Hosobe S, Tsukada T, Miura K, Takano Y, Saito K, Pauza ME, Hayashi S, Wang Y, Mohinta S, Mashimo T, Iiizumi M, Furuta E, Watabe K.

Nat Med. 2006 Aug;12(8):933-8. Epub 2006 Jul 23.


Mechanism of apoptosis induced by the inhibition of fatty acid synthase in breast cancer cells.

Bandyopadhyay S, Zhan R, Wang Y, Pai SK, Hirota S, Hosobe S, Takano Y, Saito K, Furuta E, Iiizumi M, Mohinta S, Watabe M, Chalfant C, Watabe K.

Cancer Res. 2006 Jun 1;66(11):5934-40.


The role of tumor metastasis suppressors in cancers of breast and prostate.

Furuta E, Bandyopadhyay S, Iiizumi M, Mohinta S, Zhan R, Watabe K.

Front Biosci. 2006 Sep 1;11:2845-60. Review.


Vitamin E succinate suppresses prostate tumor growth by inducing apoptosis.

Malafa MP, Fokum FD, Andoh J, Neitzel LT, Bandyopadhyay S, Zhan R, Iiizumi M, Furuta E, Horvath E, Watabe K.

Int J Cancer. 2006 May 15;118(10):2441-7.


FAS expression inversely correlates with PTEN level in prostate cancer and a PI 3-kinase inhibitor synergizes with FAS siRNA to induce apoptosis.

Bandyopadhyay S, Pai SK, Watabe M, Gross SC, Hirota S, Hosobe S, Tsukada T, Miura K, Saito K, Markwell SJ, Wang Y, Huggenvik J, Pauza ME, Iiizumi M, Watabe K.

Oncogene. 2005 Aug 11;24(34):5389-95.


Molecular features of the transition from prostatic intraepithelial neoplasia (PIN) to prostate cancer: genome-wide gene-expression profiles of prostate cancers and PINs.

Ashida S, Nakagawa H, Katagiri T, Furihata M, Iiizumi M, Anazawa Y, Tsunoda T, Takata R, Kasahara K, Miki T, Fujioka T, Shuin T, Nakamura Y.

Cancer Res. 2004 Sep 1;64(17):5963-72.


Identification of PDZK4, a novel human gene with PDZ domains, that is upregulated in synovial sarcomas.

Nagayama S, Iiizumi M, Katagiri T, Toguchida J, Nakamura Y.

Oncogene. 2004 Jul 15;23(32):5551-7.


Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53.

Mori T, Anazawa Y, Iiizumi M, Fukuda S, Nakamura Y, Arakawa H.

Oncogene. 2002 Apr 25;21(18):2914-8.


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