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Items: 30


Neurogenetic dissection of the Drosophila lateral horn reveals major outputs, diverse behavioural functions, and interactions with the mushroom body.

Dolan MJ, Frechter S, Bates AS, Dan C, Huoviala P, Roberts RJ, Schlegel P, Dhawan S, Tabano R, Dionne H, Christoforou C, Close K, Sutcliffe B, Giuliani B, Li F, Costa M, Ihrke G, Meissner GW, Bock DD, Aso Y, Rubin GM, Jefferis GS.

Elife. 2019 May 21;8. pii: e43079. doi: 10.7554/eLife.43079.


A yeast model of optineurin proteinopathy reveals a unique aggregation pattern associated with cellular toxicity.

Kryndushkin D, Ihrke G, Piermartiri TC, Shewmaker F.

Mol Microbiol. 2012 Dec;86(6):1531-47. doi: 10.1111/mmi.12075. Epub 2012 Nov 9.


Apical targeting and endocytosis of the sialomucin endolyn are essential for establishment of zebrafish pronephric kidney function.

Mo D, Ihrke G, Costa SA, Brilli L, Labilloy A, Halfter W, Cianciolo Cosentino C, Hukriede NA, Weisz OA.

J Cell Sci. 2012 Nov 15;125(Pt 22):5546-54. doi: 10.1242/jcs.111468. Epub 2012 Sep 12.


Sialylation of N-linked glycans mediates apical delivery of endolyn in MDCK cells via a galectin-9-dependent mechanism.

Mo D, Costa SA, Ihrke G, Youker RT, Pastor-Soler N, Hughey RP, Weisz OA.

Mol Biol Cell. 2012 Sep;23(18):3636-46. doi: 10.1091/mbc.E12-04-0329. Epub 2012 Aug 1. Erratum in: Mol Biol Cell. 2012 Oct;23(20):4142.


Analysis of polarized membrane traffic in hepatocytes and hepatic cell lines.

In JG, Ihrke G, Tuma PL.

Curr Protoc Cell Biol. 2012 Mar;Chapter 15:Unit 15.17. doi: 10.1002/0471143030.cb1517s54.


Multiple biosynthetic trafficking routes for apically secreted proteins in MDCK cells.

Mattila PE, Youker RT, Mo D, Bruns JR, Cresawn KO, Hughey RP, Ihrke G, Weisz OA.

Traffic. 2012 Mar;13(3):433-42. doi: 10.1111/j.1600-0854.2011.01315.x. Epub 2011 Dec 14.


Missense mutations and single nucleotide polymorphisms in ABCB11 impair bile salt export pump processing and function or disrupt pre-messenger RNA splicing.

Byrne JA, Strautnieks SS, Ihrke G, Pagani F, Knisely AS, Linton KJ, Mieli-Vergani G, Thompson RJ.

Hepatology. 2009 Feb;49(2):553-67. doi: 10.1002/hep.22683.


Differential involvement of endocytic compartments in the biosynthetic traffic of apical proteins.

Cresawn KO, Potter BA, Oztan A, Guerriero CJ, Ihrke G, Goldenring JR, Apodaca G, Weisz OA.

EMBO J. 2007 Aug 22;26(16):3737-48. Epub 2007 Aug 2.


Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cells.

Au JS, Puri C, Ihrke G, Kendrick-Jones J, Buss F.

J Cell Biol. 2007 Apr 9;177(1):103-14. Epub 2007 Apr 2.


Antibody-specific detection of caveolin-1 in subapical compartments of MDCK cells.

Bush WS, Ihrke G, Robinson JM, Kenworthy AK.

Histochem Cell Biol. 2006 Jul;126(1):27-34. Epub 2006 Jan 28.


N-glycans mediate apical recycling of the sialomucin endolyn in polarized MDCK cells.

Potter BA, Weixel KM, Bruns JR, Ihrke G, Weisz OA.

Traffic. 2006 Feb;7(2):146-54.


Differential use of two AP-3-mediated pathways by lysosomal membrane proteins.

Ihrke G, Kyttälä A, Russell MR, Rous BA, Luzio JP.

Traffic. 2004 Dec;5(12):946-62.


Two motifs target Batten disease protein CLN3 to lysosomes in transfected nonneuronal and neuronal cells.

Kyttälä A, Ihrke G, Vesa J, Schell MJ, Luzio JP.

Mol Biol Cell. 2004 Mar;15(3):1313-23. Epub 2003 Dec 29.


Non-polarized targeting of AE1 causes autosomal dominant distal renal tubular acidosis.

Devonald MA, Smith AN, Poon JP, Ihrke G, Karet FE.

Nat Genet. 2003 Feb;33(2):125-7. Epub 2003 Jan 21.


Digenic inheritance of severe insulin resistance in a human pedigree.

Savage DB, Agostini M, Barroso I, Gurnell M, Luan J, Meirhaeghe A, Harding AH, Ihrke G, Rajanayagam O, Soos MA, George S, Berger D, Thomas EL, Bell JD, Meeran K, Ross RJ, Vidal-Puig A, Wareham NJ, O'Rahilly S, Chatterjee VK, Schafer AJ.

Nat Genet. 2002 Aug;31(4):379-84. Epub 2002 Jul 15. Erratum in: Nat Genet 2002 Sep;32(1):211.


Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes.

Rous BA, Reaves BJ, Ihrke G, Briggs JA, Gray SR, Stephens DJ, Banting G, Luzio JP.

Mol Biol Cell. 2002 Mar;13(3):1071-82.


Competing sorting signals guide endolyn along a novel route to lysosomes in MDCK cells.

Ihrke G, Bruns JR, Luzio JP, Weisz OA.

EMBO J. 2001 Nov 15;20(22):6256-64.


Localization of myosin Va is dependent on the cytoskeletal organization in the cell.

Lionne C, Buss F, Hodge T, Ihrke G, Kendrick-Jones J.

Biochem Cell Biol. 2001;79(1):93-106.


Relationship between novel isoforms, functionally important domains, and subcellular distribution of CD164/endolyn.

Chan JY, Lee-Prudhoe JE, Jorgensen B, Ihrke G, Doyonnas R, Zannettino AC, Buckle VJ, Ward CJ, Simmons PJ, Watt SM.

J Biol Chem. 2001 Jan 19;276(3):2139-52. Epub 2000 Oct 10.


Syntaxin 7 is localized to late endosome compartments, associates with Vamp 8, and Is required for late endosome-lysosome fusion.

Mullock BM, Smith CW, Ihrke G, Bright NA, Lindsay M, Parkinson EJ, Brooks DA, Parton RG, James DE, Luzio JP, Piper RC.

Mol Biol Cell. 2000 Sep;11(9):3137-53.


Late endocytic compartments are major sites of annexin VI localization in NRK fibroblasts and polarized WIF-B hepatoma cells.

Pons M, Ihrke G, Koch S, Biermer M, Pol A, Grewal T, Jäckle S, Enrich C.

Exp Cell Res. 2000 May 25;257(1):33-47.


Apical plasma membrane proteins and endolyn-78 travel through a subapical compartment in polarized WIF-B hepatocytes.

Ihrke G, Martin GV, Shanks MR, Schrader M, Schroer TA, Hubbard AL.

J Cell Biol. 1998 Apr 6;141(1):115-33.


Control of vesicle traffic in hepatocytes.

Ihrke G, Hubbard AL.

Prog Liver Dis. 1995;13:63-99. Review. No abstract available.


WIF-B cells: an in vitro model for studies of hepatocyte polarity.

Ihrke G, Neufeld EB, Meads T, Shanks MR, Cassio D, Laurent M, Schroer TA, Pagano RE, Hubbard AL.

J Cell Biol. 1993 Dec;123(6 Pt 2):1761-75.


The LDL-receptor-related protein, LRP, is an apolipoprotein E-binding protein.

Beisiegel U, Weber W, Ihrke G, Herz J, Stanley KK.

Nature. 1989 Sep 14;341(6238):162-4.


Apolipoprotein E-binding proteins isolated from dog and human liver.

Beisiegel U, Weber W, Havinga JR, Ihrke G, Hui DY, Wernette-Hammond ME, Turck CW, Innerarity TL, Mahley RW.

Arteriosclerosis. 1988 May-Jun;8(3):288-97.


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