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Items: 1 to 50 of 335

2.

Nitric oxide is not just blowing in the wind.

Ignarro LJ.

Br J Pharmacol. 2019 Jan;176(2):131-134. doi: 10.1111/bph.14540.

PMID:
30556130
3.

Biological hydropersulfides and related polysulfides - a new concept and perspective in redox biology.

Fukuto JM, Ignarro LJ, Nagy P, Wink DA, Kevil CG, Feelisch M, Cortese-Krott MM, Bianco CL, Kumagai Y, Hobbs AJ, Lin J, Ida T, Akaike T.

FEBS Lett. 2018 Jun;592(12):2140-2152. doi: 10.1002/1873-3468.13090. Epub 2018 May 24. Review.

4.

Calmangafodipir [Ca4Mn(DPDP)5], mangafodipir (MnDPDP) and MnPLED with special reference to their SOD mimetic and therapeutic properties.

Karlsson JO, Ignarro LJ, Lundström I, Jynge P, Almén T.

Drug Discov Today. 2015 Apr;20(4):411-21. doi: 10.1016/j.drudis.2014.11.008. Epub 2014 Nov 20. Review.

5.

Erectile hydraulics: maximizing inflow while minimizing outflow.

Meldrum DR, Burnett AL, Dorey G, Esposito K, Ignarro LJ.

J Sex Med. 2014 May;11(5):1208-20. doi: 10.1111/jsm.12457. Epub 2014 Feb 13. Review.

PMID:
24521101
6.

Endothelial cellular senescence is inhibited by liver X receptor activation with an additional mechanism for its atheroprotection in diabetes.

Hayashi T, Kotani H, Yamaguchi T, Taguchi K, Iida M, Ina K, Maeda M, Kuzuya M, Hattori Y, Ignarro LJ.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1168-73. doi: 10.1073/pnas.1322153111. Epub 2014 Jan 7.

7.

Effects of nitric oxide on cell proliferation: novel insights.

Napoli C, Paolisso G, Casamassimi A, Al-Omran M, Barbieri M, Sommese L, Infante T, Ignarro LJ.

J Am Coll Cardiol. 2013 Jul 9;62(2):89-95. doi: 10.1016/j.jacc.2013.03.070. Epub 2013 May 9.

8.

Neuroprotective effects of valproic acid against hemin toxicity: possible involvement of the down-regulation of heme oxygenase-1 by regulating ubiquitin-proteasomal pathway.

Kwon KJ, Kim JN, Kim MK, Kim SY, Cho KS, Jeon SJ, Kim HY, Ryu JH, Han SY, Cheong JH, Ignarro LJ, Han SH, Shin CY.

Neurochem Int. 2013 Feb;62(3):240-50. doi: 10.1016/j.neuint.2012.12.019. Epub 2013 Jan 5.

PMID:
23298644
9.

Sensing endoplasmic reticulum stress by protein kinase RNA-like endoplasmic reticulum kinase promotes adaptive mitochondrial DNA biogenesis and cell survival via heme oxygenase-1/carbon monoxide activity.

Zheng M, Kim SK, Joe Y, Back SH, Cho HR, Kim HP, Ignarro LJ, Chung HT.

FASEB J. 2012 Jun;26(6):2558-68. doi: 10.1096/fj.11-199604. Epub 2012 Mar 5.

PMID:
22391129
10.

Glycoxydation promotes vascular damage via MAPK-ERK/JNK pathways.

de Nigris F, Rienzo M, Sessa M, Infante T, Cesario E, Ignarro LJ, Al-Omran M, Giordano A, Palinski W, Napoli C.

J Cell Physiol. 2012 Nov;227(11):3639-47. doi: 10.1002/jcp.24070.

PMID:
22331607
11.

Adipose tissue-derived stem cell-seeded small intestinal submucosa for tunica albuginea grafting and reconstruction.

Ma L, Yang Y, Sikka SC, Kadowitz PJ, Ignarro LJ, Abdel-Mageed AB, Hellstrom WJ.

Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):2090-5. doi: 10.1073/pnas.1113810109. Epub 2012 Jan 23.

12.

Small molecule signaling agents: the integrated chemistry and biochemistry of nitrogen oxides, oxides of carbon, dioxygen, hydrogen sulfide, and their derived species.

Fukuto JM, Carrington SJ, Tantillo DJ, Harrison JG, Ignarro LJ, Freeman BA, Chen A, Wink DA.

Chem Res Toxicol. 2012 Apr 16;25(4):769-93. doi: 10.1021/tx2005234. Epub 2012 Feb 9. Review.

13.

Nuclear fusion-independent smooth muscle differentiation of human adipose-derived stem cells induced by a smooth muscle environment.

Zhang R, Jack GS, Rao N, Zuk P, Ignarro LJ, Wu B, Rodríguez LV.

Stem Cells. 2012 Mar;30(3):481-90. doi: 10.1002/stem.1023.

14.

Lifestyle and metabolic approaches to maximizing erectile and vascular health.

Meldrum DR, Gambone JC, Morris MA, Esposito K, Giugliano D, Ignarro LJ.

Int J Impot Res. 2012 Mar-Apr;24(2):61-8. doi: 10.1038/ijir.2011.51. Epub 2011 Nov 10. Review.

PMID:
22072232
15.

The link between erectile and cardiovascular health: the canary in the coal mine.

Meldrum DR, Gambone JC, Morris MA, Meldrum DA, Esposito K, Ignarro LJ.

Am J Cardiol. 2011 Aug 15;108(4):599-606. doi: 10.1016/j.amjcard.2011.03.093. Epub 2011 May 31. Review.

PMID:
21624550
16.

Effects of ACE inhibition on circulating endothelial progenitor cells, vascular damage, and oxidative stress in hypertensive patients.

Cacciatore F, Bruzzese G, Vitale DF, Liguori A, de Nigris F, Fiorito C, Infante T, Donatelli F, Minucci PB, Ignarro LJ, Napoli C.

Eur J Clin Pharmacol. 2011 Sep;67(9):877-83. doi: 10.1007/s00228-011-1029-0. Epub 2011 Mar 29.

PMID:
21445638
17.

Regulation of tissue plasminogen activator/plasminogen activator inhibitor-1 by hydrocortisone in rat primary astrocytes.

Kwon KJ, Cho KS, Lee SH, Kim JN, Joo SH, Ryu JH, Ignarro LJ, Han SH, Shin CY.

J Neurosci Res. 2011 Jul;89(7):1059-69. doi: 10.1002/jnr.22619. Epub 2011 Mar 15.

PMID:
21412817
18.

Dose-dependent modulatory effects of insulin on glucose-induced endothelial senescence in vitro and in vivo: a relationship between telomeres and nitric oxide.

Matsui-Hirai H, Hayashi T, Yamamoto S, Ina K, Maeda M, Kotani H, Iguchi A, Ignarro LJ, Hattori Y.

J Pharmacol Exp Ther. 2011 Jun;337(3):591-9. doi: 10.1124/jpet.110.177584. Epub 2011 Feb 28.

PMID:
21357660
19.

Directed in vivo angiogenesis assay and the study of systemic neoangiogenesis in cancer.

Napoli C, Giordano A, Casamassimi A, Pentimalli F, Ignarro LJ, De Nigris F.

Int J Cancer. 2011 Apr 1;128(7):1505-8. doi: 10.1002/ijc.25743. Epub 2011 Jan 6. Review.

20.

Biphasic regulation of tissue plasminogen activator activity in ischemic rat brain and in cultured neural cells: essential role of astrocyte-derived plasminogen activator inhibitor-1.

Kim JW, Lee SH, Ko HM, Kwon KJ, Cho KS, Choi CS, Park JH, Kim HY, Lee J, Han SH, Ignarro LJ, Cheong JH, Kim WK, Shin CY.

Neurochem Int. 2011 Feb;58(3):423-33. doi: 10.1016/j.neuint.2010.12.020. Epub 2010 Dec 28.

PMID:
21193004
21.

Endothelial progenitor cells as therapeutic agents in the microcirculation: an update.

Napoli C, Hayashi T, Cacciatore F, Casamassimi A, Casini C, Al-Omran M, Ignarro LJ.

Atherosclerosis. 2011 Mar;215(1):9-22. doi: 10.1016/j.atherosclerosis.2010.10.039. Epub 2010 Nov 3. Review.

PMID:
21126740
22.

Melatonin synergistically increases resveratrol-induced heme oxygenase-1 expression through the inhibition of ubiquitin-dependent proteasome pathway: a possible role in neuroprotection.

Kwon KJ, Kim JN, Kim MK, Lee J, Ignarro LJ, Kim HJ, Shin CY, Han SH.

J Pineal Res. 2011 Mar;50(2):110-23. doi: 10.1111/j.1600-079X.2010.00820.x. Epub 2010 Nov 15.

PMID:
21073519
23.

CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy.

de Nigris F, Crudele V, Giovane A, Casamassimi A, Giordano A, Garban HJ, Cacciatore F, Pentimalli F, Marquez-Garban DC, Petrillo A, Cito L, Sommese L, Fiore A, Petrillo M, Siani A, Barbieri A, Arra C, Rengo F, Hayashi T, Al-Omran M, Ignarro LJ, Napoli C.

Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14484-9. doi: 10.1073/pnas.1008256107. Epub 2010 Jul 26. Erratum in: Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7594-7597.

24.

A multifaceted approach to maximize erectile function and vascular health.

Meldrum DR, Gambone JC, Morris MA, Ignarro LJ.

Fertil Steril. 2010 Dec;94(7):2514-20. doi: 10.1016/j.fertnstert.2010.04.026. Epub 2010 Jun 1. Review.

PMID:
20522326
25.

Therapeutic angiogenesis in diabetic apolipoprotein E-deficient mice using bone marrow cells, functional hemangioblasts and metabolic intervention.

Balestrieri ML, Lu SJ, de Nigris F, Giovane A, Williams-Ignarro S, D'Armiento FP, Feng Q, Fiorito C, Testa G, Pastore L, Cacciatore F, Mancini FP, Servillo L, De Rosa G, Pagliarulo C, Rienzo M, Minucci PB, Farzati B, Salvatore F, Rengo F, Ignarro LJ, Giordano A, Baker A, Lanza R, Napoli C.

Atherosclerosis. 2010 Apr;209(2):403-14. doi: 10.1016/j.atherosclerosis.2009.10.022. Epub 2009 Oct 29.

PMID:
19932479
26.

Nitric oxide and pathogenic mechanisms involved in the development of vascular diseases.

Napoli C, Ignarro LJ.

Arch Pharm Res. 2009 Aug;32(8):1103-8. doi: 10.1007/s12272-009-1801-1. Epub 2009 Aug 29. Review.

PMID:
19727602
27.

Preface to this special journal issue on nitric oxide chemistry and biology.

Ignarro LJ.

Arch Pharm Res. 2009 Aug;32(8):1099-101. doi: 10.1007/s12272-009-1800-2. No abstract available.

PMID:
19727601
28.

Evidence-based use of pulsed electromagnetic field therapy in clinical plastic surgery.

Strauch B, Herman C, Dabb R, Ignarro LJ, Pilla AA.

Aesthet Surg J. 2009 Mar-Apr;29(2):135-43. doi: 10.1016/j.asj.2009.02.001. Review.

PMID:
19371845
29.

Mechanisms by which exercise training benefits patients with heart failure.

Crimi E, Ignarro LJ, Cacciatore F, Napoli C.

Nat Rev Cardiol. 2009 Apr;6(4):292-300. doi: 10.1038/nrcardio.2009.8. Review.

PMID:
19352333
30.

Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation.

d'Emmanuele di Villa Bianca R, Sorrentino R, Maffia P, Mirone V, Imbimbo C, Fusco F, De Palma R, Ignarro LJ, Cirino G.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4513-8. doi: 10.1073/pnas.0807974105. Epub 2009 Mar 2.

31.

Long-term treatment with sulfhydryl angiotensin-converting enzyme inhibition reduces carotid intima-media thickening and improves the nitric oxide/oxidative stress pathways in newly diagnosed patients with mild to moderate primary hypertension.

Napoli C, Bruzzese G, Ignarro LJ, Crimi E, de Nigris F, Williams-Ignarro S, Libardi S, Sommese L, Fiorito C, Mancini FP, Cacciatore F, Liguori A.

Am Heart J. 2008 Dec;156(6):1154.e1-8. doi: 10.1016/j.ahj.2008.09.006.

PMID:
19033012
32.

Detrimental effects of Bartonella henselae are counteracted by L-arginine and nitric oxide in human endothelial progenitor cells.

Salvatore P, Casamassimi A, Sommese L, Fiorito C, Ciccodicola A, Rossiello R, Avallone B, Grimaldi V, Costa V, Rienzo M, Colicchio R, Williams-Ignarro S, Pagliarulo C, Prudente ME, Abbondanza C, Lamberti F, Baroni A, Buommino E, Farzati B, Tufano MA, Ignarro LJ, Napoli C.

Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9427-32. doi: 10.1073/pnas.0803602105. Epub 2008 Jun 30.

33.

Different pharmacological properties of two enantiomers in a unique beta-blocker, nebivolol.

Ignarro LJ.

Cardiovasc Ther. 2008 Summer;26(2):115-34. doi: 10.1111/j.1527-3466.2008.00044.x.

PMID:
18485134
34.

Therapeutic dose of nebivolol, a nitric oxide-releasing beta-blocker, reduces atherosclerosis in cholesterol-fed rabbits.

de Nigris F, Mancini FP, Balestrieri ML, Byrns R, Fiorito C, Williams-Ignarro S, Palagiano A, Crimi E, Ignarro LJ, Napoli C.

Nitric Oxide. 2008 Aug;19(1):57-63. doi: 10.1016/j.niox.2008.03.004. Epub 2008 Apr 4.

PMID:
18435936
35.

Therapeutic targeting of the stem cell niche in experimental hindlimb ischemia.

Napoli C, William-Ignarro S, Byrns R, Balestrieri ML, Crimi E, Farzati B, Mancini FP, de Nigris F, Matarazzo A, D'Amora M, Abbondanza C, Fiorito C, Giovane A, Florio A, Varricchio E, Palagiano A, Minucci PB, Tecce MF, Giordano A, Pavan A, Ignarro LJ.

Nat Clin Pract Cardiovasc Med. 2008 Sep;5(9):571-9. doi: 10.1038/ncpcardio1214. Epub 2008 Apr 15.

PMID:
18414452
36.

IL-4 and IL-13 upregulate ornithine decarboxylase expression by PI3K and MAP kinase pathways in vascular smooth muscle cells.

Wei LH, Yang Y, Wu G, Ignarro LJ.

Am J Physiol Cell Physiol. 2008 May;294(5):C1198-205. doi: 10.1152/ajpcell.00325.2007. Epub 2008 Mar 26.

37.

Deletion of Yin Yang 1 protein in osteosarcoma cells on cell invasion and CXCR4/angiogenesis and metastasis.

de Nigris F, Rossiello R, Schiano C, Arra C, Williams-Ignarro S, Barbieri A, Lanza A, Balestrieri A, Giuliano MT, Ignarro LJ, Napoli C.

Cancer Res. 2008 Mar 15;68(6):1797-808. doi: 10.1158/0008-5472.CAN-07-5582.

38.

NCX-4040, a nitric oxide-releasing aspirin, sensitizes drug-resistant human ovarian xenograft tumors to cisplatin by depletion of cellular thiols.

Bratasz A, Selvendiran K, Wasowicz T, Bobko A, Khramtsov VV, Ignarro LJ, Kuppusamy P.

J Transl Med. 2008 Feb 26;6:9. doi: 10.1186/1479-5876-6-9.

39.
40.

Functional impairment of hematopoietic progenitor cells in patients with coronary heart disease.

Liguori A, Fiorito C, Balestrieri ML, Crimi E, Bruzzese G, Williams-Ignarro S, D'Amora M, Sommese L, Grimaldi V, Minucci PB, Giovane A, Farzati B, Ignarro LJ, Napoli C.

Eur J Haematol. 2008 Mar;80(3):258-64. Epub 2007 Dec 7.

PMID:
18081701
41.

Microcirculation and oxidative stress.

Crimi E, Ignarro LJ, Napoli C.

Free Radic Res. 2007 Dec;41(12):1364-75. Review.

PMID:
18075839
42.

Therapeutic effects of autologous bone marrow cells and metabolic intervention in the ischemic hindlimb of spontaneously hypertensive rats involve reduced cell senescence and CXCR4/Akt/eNOS pathways.

de Nigris F, Balestrieri ML, Williams-Ignarro S, D'Armiento FP, Lerman LO, Byrns R, Crimi E, Palagiano A, Fatigati G, Ignarro LJ, Napoli C.

J Cardiovasc Pharmacol. 2007 Oct;50(4):424-33.

PMID:
18049311
43.

Therapeutic approaches in vascular repair induced by adult bone marrow cells and circulating progenitor endothelial cells.

Napoli C, Balestrieri A, Ignarro LJ.

Curr Pharm Des. 2007;13(31):3245-51. Review.

PMID:
18045174
44.

Effect of gestational hypercholesterolaemia on omental vasoreactivity, placental enzyme activity and transplacental passage of normal and oxidised fatty acids.

Liguori A, D'Armiento FP, Palagiano A, Balestrieri ML, Williams-Ignarro S, de Nigris F, Lerman LO, D'Amora M, Rienzo M, Fiorito C, Ignarro LJ, Palinski W, Napoli C.

BJOG. 2007 Dec;114(12):1547-56. Epub 2007 Sep 27.

45.

Heart mtNOS, a key mediator of oxidative injury in ischemia/reperfusion.

Ignarro LJ.

J Mol Cell Cardiol. 2007 Oct;43(4):409-10. Epub 2007 Jul 24. No abstract available.

PMID:
17764688
46.

Nitroaspirin (NCX-4016), an NO donor, is antiangiogenic through induction of loss of redox-dependent viability and cytoskeletal reorganization in endothelial cells.

Parinandi NL, Sharma A, Eubank TD, Kaufman BF, Kutala VK, Marsh CB, Ignarro LJ, Kuppusamy P.

Antioxid Redox Signal. 2007 Nov;9(11):1837-49.

PMID:
17760507
47.

Bone marrow cell-mediated cardiovascular repair: potential of combined therapies.

Napoli C, Maione C, Schiano C, Fiorito C, Ignarro LJ.

Trends Mol Med. 2007 Jul;13(7):278-86. Epub 2007 Jun 15.

PMID:
17574919
48.

The influence of pomegranate fruit extract in comparison to regular pomegranate juice and seed oil on nitric oxide and arterial function in obese Zucker rats.

de Nigris F, Balestrieri ML, Williams-Ignarro S, D'Armiento FP, Fiorito C, Ignarro LJ, Napoli C.

Nitric Oxide. 2007 Aug;17(1):50-4. Epub 2007 May 5.

PMID:
17553710
49.

The L-arginine paradox: Importance of the L-arginine/asymmetrical dimethylarginine ratio.

Bode-Böger SM, Scalera F, Ignarro LJ.

Pharmacol Ther. 2007 Jun;114(3):295-306. Epub 2007 Apr 1. Review.

PMID:
17482266
50.

Brain protection using autologous bone marrow cell, metalloproteinase inhibitors, and metabolic treatment in cerebral ischemia.

Baker AH, Sica V, Work LM, Williams-Ignarro S, de Nigris F, Lerman LO, Casamassimi A, Lanza A, Schiano C, Rienzo M, Ignarro LJ, Napoli C.

Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3597-602. Epub 2007 Feb 20.

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