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Items: 22

1.

Gene expression profiles define molecular subtypes of prostate cancer bone metastases with different outcomes and morphology traceable back to the primary tumor.

Thysell E, Vidman L, Ylitalo EB, Jernberg E, Crnalic S, Iglesias-Gato D, Flores-Morales A, Stattin P, Egevad L, Widmark A, Rydén P, Bergh A, Wikström P.

Mol Oncol. 2019 Aug;13(8):1763-1777. doi: 10.1002/1878-0261.12526. Epub 2019 Jun 27.

2.

Immunoreactivity for prostate specific antigen and Ki67 differentiates subgroups of prostate cancer related to outcome.

Hammarsten P, Josefsson A, Thysell E, Lundholm M, Hägglöf C, Iglesias-Gato D, Flores-Morales A, Stattin P, Egevad L, Granfors T, Wikström P, Bergh A.

Mod Pathol. 2019 Sep;32(9):1310-1319. doi: 10.1038/s41379-019-0260-6. Epub 2019 Apr 12.

3.

Proteogenomic Characterization of Patient-Derived Xenografts Highlights the Role of REST in Neuroendocrine Differentiation of Castration-Resistant Prostate Cancer.

Flores-Morales A, Bergmann TB, Lavallee C, Batth TS, Lin D, Lerdrup M, Friis S, Bartels A, Kristensen G, Krzyzanowska A, Xue H, Fazli L, Hansen KH, Røder MA, Brasso K, Moreira JM, Bjartell A, Wang Y, Olsen JV, Collins CC, Iglesias-Gato D.

Clin Cancer Res. 2019 Jan 15;25(2):595-608. doi: 10.1158/1078-0432.CCR-18-0729. Epub 2018 Oct 1.

PMID:
30274982
4.

Predictive value of combined analysis of pro-NPY and ERG in localized prostate cancer.

Kristensen G, Røder MA, Berg KD, Elversang J, Iglesias-Gato D, Moreira J, Toft BG, Brasso K.

APMIS. 2018 Oct;126(10):804-813. doi: 10.1111/apm.12886. Epub 2018 Sep 6.

PMID:
30191621
5.

SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability.

Hjorth-Jensen K, Maya-Mendoza A, Dalgaard N, Sigurðsson JO, Bartek J, Iglesias-Gato D, Olsen JV, Flores-Morales A.

Nucleic Acids Res. 2018 Oct 12;46(18):9891. doi: 10.1093/nar/gky788. No abstract available.

6.

SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability.

Hjorth-Jensen K, Maya-Mendoza A, Dalgaard N, Sigurðsson JO, Bartek J, Iglesias-Gato D, Olsen JV, Flores-Morales A.

Nucleic Acids Res. 2018 Oct 12;46(18):9484-9495. doi: 10.1093/nar/gky719. Erratum in: Nucleic Acids Res. 2018 Oct 12;46(18):9891.

7.

The Proteome of Prostate Cancer Bone Metastasis Reveals Heterogeneity with Prognostic Implications.

Iglesias-Gato D, Thysell E, Tyanova S, Crnalic S, Santos A, Lima TS, Geiger T, Cox J, Widmark A, Bergh A, Mann M, Flores-Morales A, Wikström P.

Clin Cancer Res. 2018 Nov 1;24(21):5433-5444. doi: 10.1158/1078-0432.CCR-18-1229. Epub 2018 Jul 24.

PMID:
30042207
8.

YAP1 regulates prostate cancer stem cell-like characteristics to promote castration resistant growth.

Jiang N, Ke B, Hjort-Jensen K, Iglesias-Gato D, Wang Z, Chang P, Zhao Y, Niu X, Wu T, Peng B, Jiang M, Li X, Shang Z, Wang Q, Chang C, Flores-Morales A, Niu Y.

Oncotarget. 2017 Dec 7;8(70):115054-115067. doi: 10.18632/oncotarget.23014. eCollection 2017 Dec 29.

9.

Quantitative Mass Spectrometry-Based Proteomic Profiling for Precision Medicine in Prostate Cancer.

Flores-Morales A, Iglesias-Gato D.

Front Oncol. 2017 Nov 7;7:267. doi: 10.3389/fonc.2017.00267. eCollection 2017. Review.

10.

The ubiquitin ligase Cullin5SOCS2 regulates NDR1/STK38 stability and NF-κB transactivation.

Paul I, Batth TS, Iglesias-Gato D, Al-Araimi A, Al-Haddabi I, Alkharusi A, Norstedt G, Olsen JV, Zadjali F, Flores-Morales A.

Sci Rep. 2017 Feb 20;7:42800. doi: 10.1038/srep42800.

11.

The Proteome of Primary Prostate Cancer.

Iglesias-Gato D, Wikström P, Tyanova S, Lavallee C, Thysell E, Carlsson J, Hägglöf C, Cox J, Andrén O, Stattin P, Egevad L, Widmark A, Bjartell A, Collins CC, Bergh A, Geiger T, Mann M, Flores-Morales A.

Eur Urol. 2016 May;69(5):942-52. doi: 10.1016/j.eururo.2015.10.053. Epub 2015 Dec 2.

PMID:
26651926
12.

Erratum: OTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo.

Iglesias-Gato D, Chuan YC, Jiang N, Svensson C, Bao J, Shang Z, Paul I, Egevad L, Kessler BM, Wikström P, Niu Y, Flores-Morales A.

Mol Cancer. 2015 Apr 18;14:88. doi: 10.1186/s12943-015-0341-1. No abstract available.

13.

OTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo.

Iglesias-Gato D, Chuan YC, Jiang N, Svensson C, Bao J, Paul I, Egevad L, Kessler BM, Wikström P, Niu Y, Flores-Morales A.

Mol Cancer. 2015 Jan 27;14:8. doi: 10.1186/s12943-014-0280-2. Erratum in: Mol Cancer. 2015;14:88.

14.

In vivo quantitative phosphoproteomic profiling identifies novel regulators of castration-resistant prostate cancer growth.

Jiang N, Hjorth-Jensen K, Hekmat O, Iglesias-Gato D, Kruse T, Wang C, Wei W, Ke B, Yan B, Niu Y, Olsen JV, Flores-Morales A.

Oncogene. 2015 May 21;34(21):2764-76. doi: 10.1038/onc.2014.206. Epub 2014 Jul 28.

PMID:
25065596
15.

Lipid profiling and transcriptomic analysis reveals a functional interplay between estradiol and growth hormone in liver.

Fernández-Pérez L, Santana-Farré R, de Mirecki-Garrido M, García I, Guerra B, Mateo-Díaz C, Iglesias-Gato D, Díaz-Chico JC, Flores-Morales A, Díaz M.

PLoS One. 2014 May 9;9(5):e96305. doi: 10.1371/journal.pone.0096305. eCollection 2014.

16.

Protein interaction screening for the ankyrin repeats and suppressor of cytokine signaling (SOCS) box (ASB) family identify Asb11 as a novel endoplasmic reticulum resident ubiquitin ligase.

Andresen CA, Smedegaard S, Sylvestersen KB, Svensson C, Iglesias-Gato D, Cazzamali G, Nielsen TK, Nielsen ML, Flores-Morales A.

J Biol Chem. 2014 Jan 24;289(4):2043-54. doi: 10.1074/jbc.M113.534602. Epub 2013 Dec 11.

17.

REST mediates androgen receptor actions on gene repression and predicts early recurrence of prostate cancer.

Svensson C, Ceder J, Iglesias-Gato D, Chuan YC, Pang ST, Bjartell A, Martinez RM, Bott L, Helczynski L, Ulmert D, Wang Y, Niu Y, Collins C, Flores-Morales A.

Nucleic Acids Res. 2014 Jan;42(2):999-1015. doi: 10.1093/nar/gkt921. Epub 2013 Oct 24.

18.

SOCS2 mediates the cross talk between androgen and growth hormone signaling in prostate cancer.

Iglesias-Gato D, Chuan YC, Wikström P, Augsten S, Jiang N, Niu Y, Seipel A, Danneman D, Vermeij M, Fernandez-Perez L, Jenster G, Egevad L, Norstedt G, Flores-Morales A.

Carcinogenesis. 2014 Jan;35(1):24-33. doi: 10.1093/carcin/bgt304. Epub 2013 Sep 12.

PMID:
24031028
19.

Substitution at carbon 2 of 19-nor-1α,25-dihydroxyvitamin D3 with 3-hydroxypropyl group generates an analogue with enhanced chemotherapeutic potency in PC-3 prostate cancer cells.

Iglesias-Gato D, Zheng S, Flanagan JN, Jiang L, Kittaka A, Sakaki T, Yamamoto K, Itoh T, Lebrasseur NK, Norstedt G, Chen TC.

J Steroid Biochem Mol Biol. 2011 Nov;127(3-5):269-75. doi: 10.1016/j.jsbmb.2011.08.010. Epub 2011 Sep 3.

PMID:
21911059
20.

Androgen-independent effects of Serenoa repens extract (Prostasan®) on prostatic epithelial cell proliferation and inflammation.

Iglesias-Gato D, Carsten T, Vesterlund M, Pousette A, Schoop R, Norstedt G.

Phytother Res. 2012 Feb;26(2):259-64. doi: 10.1002/ptr.3537. Epub 2011 Jun 8.

PMID:
21656602
21.

Guanine nucleotide pool imbalance impairs multiple steps of protein synthesis and disrupts GCN4 translational control in Saccharomyces cerevisiae.

Iglesias-Gato D, Martín-Marcos P, Santos MA, Hinnebusch AG, Tamame M.

Genetics. 2011 Jan;187(1):105-22. doi: 10.1534/genetics.110.122135. Epub 2010 Oct 26.

22.

Ezrin mediates c-Myc actions in prostate cancer cell invasion.

Chuan YC, Iglesias-Gato D, Fernandez-Perez L, Cedazo-Minguez A, Pang ST, Norstedt G, Pousette A, Flores-Morales A.

Oncogene. 2010 Mar 11;29(10):1531-42. doi: 10.1038/onc.2009.442. Epub 2009 Dec 14.

PMID:
20010876

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