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Items: 48

1.

Impaired geranylgeranyltransferase-I regulation reduces membrane-associated Rho protein levels in aged mouse brain.

Afshordel S, Wood WG, Igbavboa U, Muller WE, Eckert GP.

J Neurochem. 2014 May;129(4):732-42. doi: 10.1111/jnc.12654. Epub 2014 Feb 7.

2.

Evaluation of prenylated peptides for use in cellular imaging and biochemical analysis.

Ochocki JD, Igbavboa U, Wood WG, Arriaga EA, Wattenberg EV, Distefano MD.

Methods Mol Biol. 2014;1088:213-23. doi: 10.1007/978-1-62703-673-3_14.

3.

Statins, Bcl-2, and apoptosis: cell death or cell protection?

Wood WG, Igbavboa U, Muller WE, Eckert GP.

Mol Neurobiol. 2013 Oct;48(2):308-14. doi: 10.1007/s12035-013-8496-5. Epub 2013 Jul 3. Review.

4.

Brain isoprenoids farnesyl pyrophosphate and geranylgeranyl pyrophosphate are increased in aged mice.

Hooff GP, Wood WG, Kim JH, Igbavboa U, Ong WY, Muller WE, Eckert GP.

Mol Neurobiol. 2012 Aug;46(1):179-85. doi: 10.1007/s12035-012-8285-6. Epub 2012 Jun 13.

PMID:
22692983
5.

AP-2β regulates amyloid beta-protein stimulation of apolipoprotein E transcription in astrocytes.

Rossello XS, Igbavboa U, Weisman GA, Sun GY, Wood WG.

Brain Res. 2012 Mar 20;1444:87-95. doi: 10.1016/j.brainres.2012.01.017. Epub 2012 Jan 18.

6.

Cholesterol asymmetry in synaptic plasma membranes.

Wood WG, Igbavboa U, Müller WE, Eckert GP.

J Neurochem. 2011 Mar;116(5):684-9. doi: 10.1111/j.1471-4159.2010.07017.x. Epub 2011 Jan 7.

7.

Statins and neuroprotection: a prescription to move the field forward.

Wood WG, Eckert GP, Igbavboa U, Müller WE.

Ann N Y Acad Sci. 2010 Jun;1199:69-76. doi: 10.1111/j.1749-6632.2009.05359.x. Review.

8.

Enlarging the scope of cell-penetrating prenylated peptides to include farnesylated 'CAAX' box sequences and diverse cell types.

Ochocki JD, Igbavboa U, Gibson Wood W, Wattenberg EV, Distefano MD.

Chem Biol Drug Des. 2010 Aug;76(2):107-15. doi: 10.1111/j.1747-0285.2010.00992.x. Epub 2010 Jun 23.

9.

Simvastatin stimulates production of the antiapoptotic protein Bcl-2 via endothelin-1 and NFATc3 in SH-SY5Y cells.

Butterick TA, Igbavboa U, Eckert GP, Sun GY, Weisman GA, Müller WE, Wood WG.

Mol Neurobiol. 2010 Jun;41(2-3):384-91. doi: 10.1007/s12035-010-8122-8. Epub 2010 Apr 6.

10.

Regulation of the brain isoprenoids farnesyl- and geranylgeranylpyrophosphate is altered in male Alzheimer patients.

Eckert GP, Hooff GP, Strandjord DM, Igbavboa U, Volmer DA, Müller WE, Wood WG.

Neurobiol Dis. 2009 Aug;35(2):251-7. doi: 10.1016/j.nbd.2009.05.005. Epub 2009 May 21.

11.

Amyloid beta-protein stimulates trafficking of cholesterol and caveolin-1 from the plasma membrane to the Golgi complex in mouse primary astrocytes.

Igbavboa U, Sun GY, Weisman GA, He Y, Wood WG.

Neuroscience. 2009 Aug 18;162(2):328-38. doi: 10.1016/j.neuroscience.2009.04.049. Epub 2009 May 3.

12.

The interaction of beta-amyloid protein with cellular membranes stimulates its own production.

Peters I, Igbavboa U, Schütt T, Haidari S, Hartig U, Rosello X, Böttner S, Copanaki E, Deller T, Kögel D, Wood WG, Müller WE, Eckert GP.

Biochim Biophys Acta. 2009 May;1788(5):964-72. doi: 10.1016/j.bbamem.2009.01.012. Epub 2009 Feb 2.

13.

Simvastatin protects neurons from cytotoxicity by up-regulating Bcl-2 mRNA and protein.

Johnson-Anuna LN, Eckert GP, Franke C, Igbavboa U, Müller WE, Wood WG.

J Neurochem. 2007 Apr;101(1):77-86. Epub 2007 Jan 4.

14.

Amyloid beta-protein1-42 increases cAMP and apolipoprotein E levels which are inhibited by beta1 and beta2-adrenergic receptor antagonists in mouse primary astrocytes.

Igbavboa U, Johnson-Anuna LN, Rossello X, Butterick TA, Sun GY, Wood WG.

Neuroscience. 2006 Oct 27;142(3):655-60. Epub 2006 Aug 14.

PMID:
16904834
15.

Cholesterol distribution, not total levels, correlate with altered amyloid precursor protein processing in statin-treated mice.

Burns MP, Igbavboa U, Wang L, Wood WG, Duff K.

Neuromolecular Med. 2006;8(3):319-28.

PMID:
16775383
16.

Is hypercholesterolemia a risk factor for Alzheimer's disease?

Wood WG, Igbavboa U, Eckert GP, Johnson-Anuna LN, Müller WE.

Mol Neurobiol. 2005;31(1-3):185-92. Review.

PMID:
15953820
17.

Murine synaptosomal lipid raft protein and lipid composition are altered by expression of human apoE 3 and 4 and by increasing age.

Igbavboa U, Eckert GP, Malo TM, Studniski AE, Johnson LN, Yamamoto N, Kobayashi M, Fujita SC, Appel TR, Müller WE, Wood WG, Yanagisawa K.

J Neurol Sci. 2005 Mar 15;229-230:225-32. Epub 2004 Dec 16.

PMID:
15760644
18.

Chronic administration of statins alters multiple gene expression patterns in mouse cerebral cortex.

Johnson-Anuna LN, Eckert GP, Keller JH, Igbavboa U, Franke C, Fechner T, Schubert-Zsilavecz M, Karas M, Müller WE, Wood WG.

J Pharmacol Exp Ther. 2005 Feb;312(2):786-93. Epub 2004 Sep 9.

PMID:
15358814
19.

Cholesterol trafficking and amyloid beta peptides.

Wood WG, Igbavboa U.

Pharmacopsychiatry. 2003 Sep;36 Suppl 2:S144-8. Review.

PMID:
14574629
20.

Amyloid beta-protein interactions with membranes and cholesterol: causes or casualties of Alzheimer's disease.

Gibson Wood W, Eckert GP, Igbavboa U, Müller WE.

Biochim Biophys Acta. 2003 Mar 10;1610(2):281-90. Review.

21.

Cholesterol distribution in the Golgi complex of DITNC1 astrocytes is differentially altered by fresh and aged amyloid beta-peptide-(1-42).

Igbavboa U, Pidcock JM, Johnson LN, Malo TM, Studniski AE, Yu S, Sun GY, Wood WG.

J Biol Chem. 2003 May 9;278(19):17150-7. Epub 2003 Feb 12.

22.

Lipid rafts of purified mouse brain synaptosomes prepared with or without detergent reveal different lipid and protein domains.

Eckert GP, Igbavboa U, Müller WE, Wood WG.

Brain Res. 2003 Feb 7;962(1-2):144-50.

PMID:
12543465
23.

Brain membrane cholesterol domains, aging and amyloid beta-peptides.

Wood WG, Schroeder F, Igbavboa U, Avdulov NA, Chochina SV.

Neurobiol Aging. 2002 Sep-Oct;23(5):685-94. Review.

PMID:
12392774
24.

Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice.

Hayashi H, Igbavboa U, Hamanaka H, Kobayashi M, Fujita SC, Wood WG, Yanagisawa K.

Neuroreport. 2002 Mar 25;13(4):383-6.

PMID:
11930145
25.
26.

Amyloid beta-peptide1-40 increases neuronal membrane fluidity: role of cholesterol and brain region.

Chochina SV, Avdulov NA, Igbavboa U, Cleary JP, O'Hare EO, Wood WG.

J Lipid Res. 2001 Aug;42(8):1292-7.

27.

Lipid carrier proteins and ethanol.

Wood WG, Avdulov NA, Chochina SV, Igbavboa U.

J Biomed Sci. 2001 Jan-Feb;8(1):114-8.

PMID:
11173984
29.

Expression of fatty acid binding proteins is altered in aged mouse brain.

Pu L, Igbavboa U, Wood WG, Roths JB, Kier AB, Spener F, Schroeder F.

Mol Cell Biochem. 1999 Aug;198(1-2):69-78.

PMID:
10497880
30.

Distribution and fluidizing action of soluble and aggregated amyloid beta-peptide in rat synaptic plasma membranes.

Mason RP, Jacob RF, Walter MF, Mason PE, Avdulov NA, Chochina SV, Igbavboa U, Wood WG.

J Biol Chem. 1999 Jun 25;274(26):18801-7.

31.

Recent advances in brain cholesterol dynamics: transport, domains, and Alzheimer's disease.

Wood WG, Schroeder F, Avdulov NA, Chochina SV, Igbavboa U.

Lipids. 1999 Mar;34(3):225-34. Review.

PMID:
10230715
32.

Lipid binding to sterol carrier protein-2 is inhibited by ethanol.

Avdulov NA, Chochina SV, Igbavboa U, Warden CS, Schroeder F, Wood WG.

Biochim Biophys Acta. 1999 Jan 29;1437(1):37-45.

PMID:
9931423
33.

Age differences in the expression of metabotropic glutamate receptor 1 and inositol 1,4,5-trisphosphate receptor in mouse cerebellum.

Simonyi A, Xia J, Igbavboa U, Wood WG, Sun GY.

Neurosci Lett. 1998 Mar 6;244(1):29-32.

PMID:
9578137
34.

Lipid binding to amyloid beta-peptide aggregates: preferential binding of cholesterol as compared with phosphatidylcholine and fatty acids.

Avdulov NA, Chochina SV, Igbavboa U, Warden CS, Vassiliev AV, Wood WG.

J Neurochem. 1997 Oct;69(4):1746-52.

36.

Amyloid beta-peptides increase annular and bulk fluidity and induce lipid peroxidation in brain synaptic plasma membranes.

Avdulov NA, Chochina SV, Igbavboa U, O'Hare EO, Schroeder F, Cleary JP, Wood WG.

J Neurochem. 1997 May;68(5):2086-91.

37.

Increasing age alters transbilayer fluidity and cholesterol asymmetry in synaptic plasma membranes of mice.

Igbavboa U, Avdulov NA, Schroeder F, Wood WG.

J Neurochem. 1996 Apr;66(4):1717-25.

PMID:
8627330
38.

Cholesterol oxidation reduces Ca(2+)+MG (2+)-ATPase activity, interdigitation, and increases fluidity of brain synaptic plasma membranes.

Wood WG, Igbavboa U, Rao AM, Schroeder F, Avdulov NA.

Brain Res. 1995 Jun 12;683(1):36-42.

PMID:
7552342
39.

Structure and polarity of mouse brain synaptic plasma membrane: effects of ethanol in vitro and in vivo.

Colles S, Wood WG, Myers-Payne SC, Igbavboa U, Avdulov NA, Joseph J, Schroeder F.

Biochemistry. 1995 May 2;34(17):5945-59.

PMID:
7727452
40.
41.

Cholesterol exchange and lateral cholesterol pools in synaptosomal membranes of pair-fed control and chronic ethanol-treated mice.

Wood WG, Rao AM, Igbavboa U, Semotuk M.

Alcohol Clin Exp Res. 1993 Apr;17(2):345-50.

PMID:
8488977
42.

Transient induction of the mitochondrial permeability transition by uncoupler plus a Ca(2+)-specific chelator.

Igbavboa U, Pfeiffer DR.

Biochim Biophys Acta. 1991 Sep 13;1059(3):339-47.

PMID:
1716985
45.

Release of mitochondrial matrix proteins through a Ca2+-requiring, cyclosporin-sensitive pathway.

Igbavboa U, Zwizinski CW, Pfeiffer DR.

Biochem Biophys Res Commun. 1989 Jun 15;161(2):619-25.

PMID:
2500122
47.

Permeability pathways of Ca2+ efflux from mitochondria: H+ specificity and reversibility of the permeability defect.

Pfeiffer DR, Broekemeier KM, Igbavboa U, Reers M, Riley WW Jr.

Adv Exp Med Biol. 1988;232:15-23. No abstract available.

PMID:
3145678
48.

Alternative formation of anthraquinones and lipoquinones in heterotrophic and photoautotrophic cell suspension cultures of Morinda lucida Benth.

Igbavboa U, Sieweke HJ, Leistner E, Röwer I, Hüsemann W, Barz W.

Planta. 1985 Dec;166(4):537-44. doi: 10.1007/BF00391279.

PMID:
24241620

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