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Items: 1 to 50 of 1672

1.

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.

Hinohara K, Wu HJ, Sébastien Vigneau, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales SC, Lal-Nag M, Rai G, Maloney DJ, Jadhav A, Simeonov A, Wagle N, Brown M, Meissner A, Sicinski P, Jaffe JD, Jeselsohn R, Gimelbrant AA, Michor F, Polyak K.

Cancer Cell. 2019 Feb 11;35(2):330-332. doi: 10.1016/j.ccell.2019.01.012. No abstract available.

PMID:
30753830
2.

Elucidation of secondary alcohol metabolism in Starmerella bombicola and contribution of primary alcohol oxidase FAO1.

Takahashi F, Igarashi K, Takimura Y, Yamamoto T.

FEMS Yeast Res. 2019 Feb 11. doi: 10.1093/femsyr/foz012. [Epub ahead of print]

PMID:
30753455
3.

Analyses of the possible anti-tumor effect of yokukansan.

Han C, Kawata M, Hamada Y, Kondo T, Wada J, Asano K, Makabe H, Igarashi K, Kuzumaki N, Narita M, Kobayashi H, Narita M.

J Nat Med. 2019 Feb 9. doi: 10.1007/s11418-019-01283-x. [Epub ahead of print]

PMID:
30739283
4.

Randomized placebo-controlled double-blind phase II study of zaltoprofen for patients with diffuse-type and unresectable localized tenosynovial giant cell tumors: a study protocol.

Takeuchi A, Nomura A, Yamamoto N, Hayashi K, Igarashi K, Tandai S, Kawai A, Matsumine A, Miwa S, Nishida Y, Nakamura T, Terauchi R, Hoshi M, Kunisada T, Endo M, Yoshimura K, Murayama T, Tsuchiya H.

BMC Musculoskelet Disord. 2019 Feb 9;20(1):68. doi: 10.1186/s12891-019-2453-z.

5.

Aberrant epigenetic gene regulation in hippocampal neurogenesis of mouse offspring following maternal exposure to 3,3'-iminodipropionitrile.

Tanaka T, Nakajima K, Masubuchi Y, Ito Y, Kikuchi S, Ideta-Ohtsuka M, Woo GH, Yoshida T, Igarashi K, Shibutani M.

J Toxicol Sci. 2019;44(2):93-105. doi: 10.2131/jts.44.93.

6.

High Efficacy of Recombinant Methioninase on Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Cancer.

Hoffman RM, Murakami T, Kawaguchi K, Igarashi K, Tan Y, Li S, Han Q.

Methods Mol Biol. 2019;1866:149-161. doi: 10.1007/978-1-4939-8796-2_12.

PMID:
30725414
7.

Methioninase Cell-Cycle Trap Cancer Chemotherapy.

Hoffman RM, Yano S, Igarashi K.

Methods Mol Biol. 2019;1866:133-148. doi: 10.1007/978-1-4939-8796-2_11.

PMID:
30725413
8.

Current and Emerging Targets in Immunotherapy for Osteosarcoma.

Miwa S, Shirai T, Yamamoto N, Hayashi K, Takeuchi A, Igarashi K, Tsuchiya H.

J Oncol. 2019 Jan 1;2019:7035045. doi: 10.1155/2019/7035045. eCollection 2019. Review.

9.

Clinical significance of cancer specific methylation of the CDO1 gene in small bowel cancer.

Kojima K, Nakamura T, Ooizumi Y, Igarashi K, Tanaka T, Yokoi K, Ishii S, Nishizawa N, Katoh H, Kosaka Y, Sato T, Watanabe M, Yamashita K.

PLoS One. 2019 Jan 24;14(1):e0211108. doi: 10.1371/journal.pone.0211108. eCollection 2019.

10.

Dissected peripancreatic tissue margin is a critical prognostic factor and is associated with a K-ras gene mutation in pancreatic ductal adenocarcinoma.

Nishizawa N, Kumamoto Y, Katoh H, Ushiku H, Yokoi K, Tanaka T, Ishii S, Igarashi K, Tajima H, Kaizu T, Yoshida T, Saegusa M, Watanabe M, Yamashita K.

Oncol Lett. 2019 Feb;17(2):2141-2150. doi: 10.3892/ol.2018.9839. Epub 2018 Dec 17.

11.

Survey of suspected dysphagia prevalence in home-dwelling older people using the 10-Item Eating Assessment Tool (EAT-10).

Igarashi K, Kikutani T, Tamura F.

PLoS One. 2019 Jan 23;14(1):e0211040. doi: 10.1371/journal.pone.0211040. eCollection 2019.

12.

[Participation/Dispatch Reports on the 46th Autumn Meeting].

Yamamoto T, Wada N, Ogawa Y, Igarashi K, Murakami R, Ueki T, Sugeno K, Kitahara Y, Nagasawa R, Maru Y, Tsujimoto R, Tajiri Y.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2019;75(1):111-124. doi: 10.6009/jjrt.2019_JSRT_75.1.111. Japanese. No abstract available.

13.

Recovering metals from aqueous solutions by biosorption onto phosphorylated dry baker's yeast.

Ojima Y, Kosako S, Kihara M, Miyoshi N, Igarashi K, Azuma M.

Sci Rep. 2019 Jan 18;9(1):225. doi: 10.1038/s41598-018-36306-2.

14.

de novo transcription of multiple Hox cluster genes takes place simultaneously in early Xenopus tropicalis embryos.

Kondo M, Matsuo M, Igarashi K, Haramoto Y, Yamamoto T, Yasuoka Y, Taira M.

Biol Open. 2019 Jan 16. pii: bio.038422. doi: 10.1242/bio.038422. [Epub ahead of print]

15.

[MPMBP, a novel bisphosphonate with an antioxidant side chain, stimulates bone formation through inhibition of NF-κB nuclear translocation].

Suzuki K, Nagaoka M, Igarashi K, Shinoda H.

Nihon Yakurigaku Zasshi. 2019;153(1):4-10. doi: 10.1254/fpj.153.4. Japanese.

PMID:
30643091
16.

Therapeutic Targets for Bone and Soft-Tissue Sarcomas.

Miwa S, Yamamoto N, Hayashi K, Takeuchi A, Igarashi K, Tsuchiya H.

Int J Mol Sci. 2019 Jan 4;20(1). pii: E170. doi: 10.3390/ijms20010170. Review.

17.

The combination of gemcitabine and nab-paclitaxel as a novel effective treatment strategy for undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model.

Higuchi T, Kawaguchi K, Miyake K, Oshiro H, Zhang Z, Razmjooei S, Wangsiricharoen S, Igarashi K, Yamamoto N, Hayashi K, Kimura H, Miwa S, Nelson SD, Dry SM, Li Y, Chawla SP, Eilber FC, Singh SR, Tsuchiya H, Hoffman RM.

Biomed Pharmacother. 2019 Jan 4;111:835-840. doi: 10.1016/j.biopha.2018.12.110. [Epub ahead of print]

18.

Lactate Dehydrogenase C Is Required for the Protein Expression of a Sperm-specific Isoform of Lactate Dehydrogenase A.

Dodo M, Kitamura H, Shima H, Saigusa D, Wati SM, Ota N, Katsuoka F, Chiba H, Okae H, Arima T, Igarashi K, Koseki T, Sekine H, Motohashi H.

J Biochem. 2018 Dec 24. doi: 10.1093/jb/mvy108. [Epub ahead of print]

PMID:
30590713
19.

Validity of a visual scoring method using gummy jelly for evaluating chewing efficiency in a large-scale epidemiological survey.

Igarashi K, Watanabe Y, Kugimiya Y, Shirobe M, Edahiro A, Kaneda K, Hasegawa Y, Ito M, Hirano H, Sakurai K, Ono T, Inagaki H, Awata S, Kawai Y.

J Oral Rehabil. 2018 Dec 27. doi: 10.1111/joor.12761. [Epub ahead of print]

PMID:
30588657
20.

Hemoglobin-albumin cluster: physiological responses after exchange transfusion into rats and blood circulation persistence in dogs.

Iwasaki H, Yokomaku K, Kureishi M, Igarashi K, Hashimoto R, Kohno M, Iwazaki M, Haruki R, Akiyama M, Asai K, Nakamura Y, Funaki R, Morita Y, Komatsu T.

Artif Cells Nanomed Biotechnol. 2018 Dec 25:1-9. doi: 10.1080/21691401.2018.1505740. [Epub ahead of print]

PMID:
30585092
21.

Fungal PQQ-dependent dehydrogenases and their potential in biocatalysis.

Takeda K, Umezawa K, Várnai A, Eijsink VG, Igarashi K, Yoshida M, Nakamura N.

Curr Opin Chem Biol. 2018 Dec 20;49:113-121. doi: 10.1016/j.cbpa.2018.12.001. [Epub ahead of print] Review.

PMID:
30580186
22.

The functional role of polyamines in eukaryotic cells.

Igarashi K, Kashiwagi K.

Int J Biochem Cell Biol. 2019 Feb;107:104-115. doi: 10.1016/j.biocel.2018.12.012. Epub 2018 Dec 20. Review.

PMID:
30578954
23.

Extracellular Electron Transfer via Outer Membrane Cytochromes in a Methanotrophic Bacterium Methylococcus capsulatus (Bath).

Tanaka K, Yokoe S, Igarashi K, Takashino M, Ishikawa M, Hori K, Nakanishi S, Kato S.

Front Microbiol. 2018 Nov 29;9:2905. doi: 10.3389/fmicb.2018.02905. eCollection 2018.

24.

Lysophospholipids in laboratory medicine.

Yatomi Y, Kurano M, Ikeda H, Igarashi K, Kano K, Aoki J.

Proc Jpn Acad Ser B Phys Biol Sci. 2018;94(10):373-389. doi: 10.2183/pjab.94.025. Review.

25.

Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2.

Nishimura T, Nakata A, Chen X, Nishi K, Meguro-Horike M, Sasaki S, Kita K, Horike SI, Saitoh K, Kato K, Igarashi K, Murayama T, Kohno S, Takahashi C, Mukaida N, Yano S, Soga T, Tojo A, Gotoh N.

Oncogene. 2018 Dec 7. doi: 10.1038/s41388-018-0589-1. [Epub ahead of print]

PMID:
30532069
26.

ANNALS EXPRESS: Autotaxin and sIL-2R levels in cerebrospinal fluids are useful for the diagnosis of central nervous system invasion caused by hematological malignancies.

Shimura T, Kurano M, Morita Y, Yoshikawa N, Nishikawa M, Igarashi K, Shimamoto S, Aoki J, Yatomi Y.

Ann Clin Biochem. 2018 Dec 4:4563218818197. doi: 10.1177/0004563218818197. [Epub ahead of print]

PMID:
30514094
27.

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.

Hinohara K, Wu HJ, Vigneau S, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales SC, Lal-Nag M, Rai G, Maloney DJ, Jadhav A, Simeonov A, Wagle N, Brown M, Meissner A, Sicinski P, Jaffe JD, Jeselsohn R, Gimelbrant AA, Michor F, Polyak K.

Cancer Cell. 2018 Dec 10;34(6):939-953.e9. doi: 10.1016/j.ccell.2018.10.014. Epub 2018 Nov 21. Erratum in: Cancer Cell. 2019 Feb 11;35(2):330-332.

PMID:
30472020
28.

Simultaneous acquisition of magnetic resonance elastography of the supraspinatus and the trapezius muscles.

Ito D, Numano T, Takamoto K, Ueki T, Habe T, Igarashi K, Mizuhara K, Nishijo H.

Magn Reson Imaging. 2019 Apr;57:95-102. doi: 10.1016/j.mri.2018.11.011. Epub 2018 Nov 19.

PMID:
30465866
29.

Autotaxin and vascular endothelial growth factor receptor-2 and -3 are related to vascular development during the progression of chronic viral hepatitis C.

Yokomori H, Ando W, Kaneko F, Suzuki H, Igarashi K, Oda M.

APMIS. 2018 Dec;126(12):913-921. doi: 10.1111/apm.12904.

PMID:
30456868
30.

Polyamines stimulate the CHSY1 synthesis through the unfolding of the RNA G-quadruplex at the 5'-untraslated region.

Yamaguchi K, Asakura K, Imamura M, Kawai G, Sakamoto T, Furihata T, Linhardt RJ, Igarashi K, Toida T, Higashi K.

Biochem J. 2018 Dec 6;475(23):3797-3812. doi: 10.1042/BCJ20180672.

PMID:
30401686
31.

Metabolic targeting with recombinant methioninase combined with palbociclib regresses a doxorubicin-resistant dedifferentiated liposarcoma.

Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Miyaki M, Yamamoto N, Hayashi K, Kimura H, Miwa S, Higuchi T, Singh AS, Chmielowski B, Nelson SD, Russell TA, Eckardt MA, Dry SM, Li Y, Singh SR, Chawla SP, Eilber FC, Tsuchiya H, Hoffman RM.

Biochem Biophys Res Commun. 2018 Dec 2;506(4):912-917. doi: 10.1016/j.bbrc.2018.10.119. Epub 2018 Nov 2.

PMID:
30392912
32.

Perioperative serum and urine metabolome analyses in patients with hepatocellular carcinoma undergoing partial hepatectomy.

Kajiura D, Yamanaka-Okumura H, Hirayama A, Tatano H, Endo K, Honma M, Igarashi K, Shoji F, Ikeda S, Yamaguchi N, Katayama T, Morine Y, Imura S, Utsunomiya T, Soga T, Tomita M, Shimada M.

Nutrition. 2019 Feb;58:110-119. doi: 10.1016/j.nut.2018.06.002. Epub 2018 Aug 7.

PMID:
30391689
33.

The usefulness of wide excision assisted by a computer navigation system and reconstruction using a frozen bone autograft for malignant acetabular bone tumors: a report of two cases.

Abe K, Yamamoto N, Hayashi K, Takeuchi A, Miwa S, Igarashi K, Inatani H, Aoki Y, Higuchi T, Taniguchi Y, Yonezawa H, Araki Y, Tsuchiya H.

BMC Cancer. 2018 Oct 24;18(1):1036. doi: 10.1186/s12885-018-4971-8.

34.

Target of rapamycin-signaling modulates starch accumulation via glycogenin phosphorylation status in the unicellular red alga Cyanidioschyzon merolae.

Pancha I, Shima H, Higashitani N, Igarashi K, Higashitani A, Tanaka K, Imamura S.

Plant J. 2019 Feb;97(3):485-499. doi: 10.1111/tpj.14136. Epub 2018 Nov 28.

PMID:
30351485
35.
36.

Methylated promoter DNA of CDO1 gene and preoperative serum CA19-9 are prognostic biomarkers in primary extrahepatic cholangiocarcinoma.

Nakamoto S, Kumamoto Y, Igarashi K, Fujiyama Y, Nishizawa N, Ei S, Tajima H, Kaizu T, Watanabe M, Yamashita K.

PLoS One. 2018 Oct 16;13(10):e0205864. doi: 10.1371/journal.pone.0205864. eCollection 2018.

37.

[Hematopoietic cell differentiation orchestrated by transcription factor network and its related pathogenesis].

Kato H, Igarashi K.

Rinsho Ketsueki. 2018;59(10):1872-1879. doi: 10.11406/rinketsu.59.1872. Japanese.

PMID:
30305487
38.

A combination of irinotecan/cisplatinum and irinotecan/temozolomide or tumor-targeting Salmonella typhimurium A1-R arrest doxorubicin- and temozolomide-resistant myxofibrosarcoma in a PDOX mouse model.

Kiyuna T, Tome Y, Murakami T, Miyake K, Igarashi K, Kawaguchi K, Oshiro H, Higuchi T, Miyake M, Sugisawa N, Zhang Z, Razmjooei S, Wangsiricharoen S, Chmielowski B, Nelson SD, Russell TA, Dry SM, Li Y, Eckardt MA, Singh AS, Chawla S, Kanaya F, Eilber FC, Singh SR, Zhao M, Hoffman RM.

Biochem Biophys Res Commun. 2018 Nov 2;505(3):733-739. doi: 10.1016/j.bbrc.2018.09.106. Epub 2018 Oct 3.

PMID:
30292411
39.

Oral Recombinant Methioninase Combined with Caffeine and Doxorubicin Induced Regression of a Doxorubicin-resistant Synovial Sarcoma in a PDOX Mouse Model.

Higuchi T, Kawaguchi K, Miyake K, Han Q, Tan Y, Oshiro H, Sugisawa N, Zhang Z, Razmjooei S, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Chawla SP, Singh AS, Eilber FC, Singh SR, Tsuchiya H, Hoffman RM.

Anticancer Res. 2018 Oct;38(10):5639-5644. doi: 10.21873/anticanres.12899.

PMID:
30275182
40.

Antioxidant and hepatoprotective activity of kaempferol 3-O-β-d- (2,6-di-O-α-l-rhamnopyranosyl)galactopyronoside against carbon tetrachloride-induced liver injury in mice.

Zang Y, Zhang D, Yu C, Jin C, Igarashi K.

Food Sci Biotechnol. 2017 Aug 18;26(4):1071-1076. doi: 10.1007/s10068-017-0170-7. eCollection 2017.

41.

Infection perturbs Bach2- and Bach1-dependent erythroid lineage 'choice' to cause anemia.

Kato H, Itoh-Nakadai A, Matsumoto M, Ishii Y, Watanabe-Matsui M, Ikeda M, Ebina-Shibuya R, Sato Y, Kobayashi M, Nishizawa H, Suzuki K, Muto A, Fujiwara T, Nannya Y, Malcovati L, Cazzola M, Ogawa S, Harigae H, Igarashi K.

Nat Immunol. 2018 Oct;19(10):1059-1070. doi: 10.1038/s41590-018-0202-3. Epub 2018 Sep 24.

PMID:
30250186
42.

Neutrophil-to-lymphocyte ratio as a predictor of postoperative morbidity in patients with distal cholangiocarcinoma.

Kumamoto Y, Kaizu T, Tajima H, Nishizawa N, Ei S, Igarashi K, Watanabe M.

Mol Clin Oncol. 2018 Oct;9(4):362-368. doi: 10.3892/mco.2018.1698. Epub 2018 Aug 14.

43.

Serum Autotaxin Concentrations Reflect Changes in Liver Stiffness and Fibrosis After Antiviral Therapy in Patients with Chronic Hepatitis C.

Ando W, Yokomori H, Kaneko F, Kaneko M, Igarashi K, Suzuki H.

Hepatol Commun. 2018 Aug 23;2(9):1111-1122. doi: 10.1002/hep4.1230. eCollection 2018 Sep.

44.

Clinically relevant radioresistant cells exhibit resistance to H2O2 by decreasing internal H2O2 and lipid peroxidation.

Tomita K, Kuwahara Y, Takashi Y, Igarashi K, Nagasawa T, Nabika H, Kurimasa A, Fukumoto M, Nishitani Y, Sato T.

Tumour Biol. 2018 Sep;40(9):1010428318799250. doi: 10.1177/1010428318799250.

PMID:
30192208
45.

Data on the aquaporin gene expression differences among ρ0, clinically relevant radioresistant, and the parental cells of human cervical cancer and human tongue squamous cell carcinoma.

Takashi Y, Tomita K, Kuwahara Y, Nabika H, Igarashi K, Nagasawa T, Kurimasa A, Fukumoto M, Nishitani Y, Sato T.

Data Brief. 2018 Aug 15;20:402-410. doi: 10.1016/j.dib.2018.08.025. eCollection 2018 Oct.

46.

Combination therapy of tumor-targeting Salmonella typhimurium A1-R and oral recombinant methioninase regresses a BRAF-V600E-negative melanoma.

Kawaguchi K, Higuchi T, Li S, Han Q, Tan Y, Igarashi K, Zhao M, Miyake K, Kiyuna T, Miyake M, Ohshiro H, Sugisawa N, Zhang Z, Razmjooei S, Wangsiricharoen S, Chmielowski B, Nelson SD, Russell TA, Dry SM, Li Y, Eckardt MA, Singh AS, Singh SR, Eilber FC, Unno M, Hoffman RM.

Biochem Biophys Res Commun. 2018 Sep 18;503(4):3086-3092. doi: 10.1016/j.bbrc.2018.08.097. Epub 2018 Aug 27.

PMID:
30166061
47.

Trabectedin arrests a doxorubicin-resistant PDGFRA-activated liposarcoma patient-derived orthotopic xenograft (PDOX) nude mouse model.

Kiyuna T, Tome Y, Murakami T, Kawaguchi K, Igarashi K, Miyake K, Miyake M, Li Y, Nelson SD, Dry SM, Singh AS, Russell TA, Elliott I, Singh SR, Kanaya F, Eilber FC, Hoffman RM.

BMC Cancer. 2018 Aug 20;18(1):840. doi: 10.1186/s12885-018-4703-0.

48.

Effects of polyamines on protein synthesis and growth of Escherichia coli.

Igarashi K, Kashiwagi K.

J Biol Chem. 2018 Nov 30;293(48):18702-18709. doi: 10.1074/jbc.TM118.003465. Epub 2018 Aug 14. Review.

PMID:
30108177
49.

Executive function predicts the visuospatial working memory in autism spectrum disorder and attention-deficit/hyperactivity disorder.

Wang Z, Jing J, Igarashi K, Fan L, Yang S, Li Y, Jin Y.

Autism Res. 2018 Aug;11(8):1148-1156. doi: 10.1002/aur.1967. Epub 2018 Aug 10.

PMID:
30095242
50.

Hand Dexterity Impairment in Patients with Cervical Myelopathy: A New Quantitative Assessment Using a Natural Prehension Movement.

Omori M, Shibuya S, Nakajima T, Endoh T, Suzuki S, Irie S, Ariyasu R, Unenaka S, Sano H, Igarashi K, Ichimura S, Ohki Y.

Behav Neurol. 2018 Jul 4;2018:5138234. doi: 10.1155/2018/5138234. eCollection 2018.

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