1.

Evaluation of the Pharmacokinetics, Safety, and Tolerability of a Single Oral Dose of Pyrimethamine in Healthy Male Subjects of Japanese and European Ancestry.

Iida T, Nand RA, Ino H, Ogura H, Itoh H, Igarashi H, Numachi Y, Gross AS.

Clin Pharmacol Drug Dev. 2020 Jan 16. doi: 10.1002/cpdd.771. [Epub ahead of print]

PMID:
31950646
2.

Suitable methods of measuring acceleration time in the diagnosis of internal carotid artery stenosis.

Iizuka K, Takekawa H, Iwasaki A, Igarashi H, Suzuki K, Kobayashi S, Tsukui D, Hirata K.

J Med Ultrason (2001). 2020 Jan 7. doi: 10.1007/s10396-019-01000-x. [Epub ahead of print]

PMID:
31912319
3.

Oxygen use and survival in patients with advanced cancer and low oxygen saturation in home care: a preliminary retrospective cohort study.

Igarashi H, Fukushi M, Nago N.

BMC Palliat Care. 2020 Jan 3;19(1):3. doi: 10.1186/s12904-019-0511-9.

4.

Characterization of glycoconjugates and sialic acid modification in the olfactory bulb of the Chinese fire-bellied newt (Cynops orientalis).

Matsui T, Komamoto K, Igarashi H, Kurohmaru M.

Anat Histol Embryol. 2019 Dec 18. doi: 10.1111/ahe.12524. [Epub ahead of print]

PMID:
31854005
5.

Biochemical analysis of a new sugary-type rice mutant, Hemisugary1, carrying a novel allele of the sugary-1 gene.

Takahashi S, Kumagai Y, Igarashi H, Horimai K, Ito H, Shimada T, Kato Y, Hamada S.

Planta. 2019 Dec 4;251(1):29. doi: 10.1007/s00425-019-03321-0.

PMID:
31802247
6.

Vascular Hyperintensity on Fluid-Attenuated Inversion Recovery Indicates the Severity of Hypoperfusion in Acute Stroke.

Nomura T, Okamoto K, Igarashi H, Watanabe M, Hasegawa H, Oishi M, Fujii Y.

J Stroke Cerebrovasc Dis. 2020 Feb;29(2):104467. doi: 10.1016/j.jstrokecerebrovasdis.2019.104467. Epub 2019 Nov 22.

7.

PRDM14 promotes malignant phenotype and correlates with poor prognosis in colorectal cancer.

Igarashi H, Taniguchi H, Nosho K, Ishigami K, Koide H, Mitsuhashi K, Okita K, Takemasa I, Imai K, Nakase H.

Clin Transl Oncol. 2019 Nov 18. doi: 10.1007/s12094-019-02239-z. [Epub ahead of print]

PMID:
31741141
8.

Optogenetic analysis of respiratory neuronal networks in the ventral medulla of neonatal rats producing channelrhodopsin in Phox2b-positive cells.

Ikeda K, Igarashi H, Yawo H, Kobayashi K, Arata S, Kawakami K, Izumizaki M, Onimaru H.

Pflugers Arch. 2019 Dec;471(11-12):1419-1439. doi: 10.1007/s00424-019-02317-9. Epub 2019 Oct 20.

PMID:
31631251
9.

Y chromosome microdeletion screening using a new molecular diagnostic method in 1030 Japanese males with infertility.

Iijima M, Shigehara K, Igarashi H, Kyono K, Suzuki Y, Tsuji Y, Kobori Y, Kobayashi H, Mizokami A.

Asian J Androl. 2019 Oct 11. doi: 10.4103/aja.aja_97_19. [Epub ahead of print]

10.

Glial pathology in a novel spontaneous mutant mouse of the Eif2b5 gene: a vanishing white matter disease model.

Terumitsu-Tsujita M, Kitaura H, Miura I, Kiyama Y, Goto F, Muraki Y, Ominato S, Hara N, Simankova A, Bizen N, Kashiwagi K, Ito T, Toyoshima Y, Kakita A, Manabe T, Wakana S, Takebayashi H, Igarashi H.

J Neurochem. 2019 Oct 6. doi: 10.1111/jnc.14887. [Epub ahead of print]

PMID:
31587290
11.

Distribution of regulatory T cells in inflammatory colorectal polyps of miniature dachshunds.

Konishi K, Igarashi H, Maeda S, Uchida E, Hanazono K, Tamamoto T, Uchida K, Endoh D, Ohno K.

Vet Immunol Immunopathol. 2019 Dec;218:109938. doi: 10.1016/j.vetimm.2019.109938. Epub 2019 Sep 3.

PMID:
31518913
12.

Identifying the Factors Governing the Early-Stage Degradation of Cu-Chabazite Zeolite for NH3-SCR.

Usui T, Liu Z, Igarashi H, Sasaki Y, Shiramata Y, Yamada H, Ohara K, Kusamoto T, Wakihara T.

ACS Omega. 2019 Feb 19;4(2):3653-3659. doi: 10.1021/acsomega.8b03409. eCollection 2019 Feb 28.

13.

Auditory T-Complex Reveals Reduced Neural Activities in the Right Auditory Cortex in Musicians With Absolute Pitch.

Matsuda M, Igarashi H, Itoh K.

Front Neurosci. 2019 Aug 6;13:809. doi: 10.3389/fnins.2019.00809. eCollection 2019.

14.

Prognostic importance of peritoneal washing cytology in patients with otherwise resectable pancreatic ductal adenocarcinoma who underwent pancreatectomy: A nationwide, cancer registry-based study from the Japan Pancreas Society.

Tsuchida H, Fujii T, Mizuma M, Satoi S, Igarashi H, Eguchi H, Kuroki T, Shimizu Y, Tani M, Tanno S, Tsuji Y, Hirooka Y, Masamune A, Mizumoto K, Itoi T, Egawa S, Kodama Y, Hamada S, Unno M, Yamaue H, Okazaki K; Committee of Clinical Research, Japan Pancreas Society.

Surgery. 2019 Dec;166(6):997-1003. doi: 10.1016/j.surg.2019.06.023. Epub 2019 Aug 21.

PMID:
31445763
15.

The 10th Japan Bioanalysis Forum Symposium conference: a report.

Sano Y, Ohtsu Y, Igarashi H, Hosogi J, Komaba J, Mabuchi M, Yamaguchi T, Kamimori H, Arakawa T, Nakamura T, Nakai K, Hara H, Kakehi M, Suzuki S, Uchiyama H, Kawai Y, Nagao A, Nishiguchi Y.

Bioanalysis. 2019 Jul;11(14):1303-1308. doi: 10.4155/bio-2019-0174. Epub 2019 Aug 8.

16.

Distribution of actin filaments in the seminiferous epithelium of the Habu, Trimeresurus flavoviridis.

Kurohmaru M, Matsui T, Igarashi H, Hattori S, Hayashi Y.

Anat Histol Embryol. 2019 Sep;48(5):505-507. doi: 10.1111/ahe.12475. Epub 2019 Aug 7.

PMID:
31389074
17.

Anatomical Evaluation of the Sacral Hiatus Using Ultrasound Imaging: Factors That Inhibit Needle Insertion During Caudal Epidural Block Procedures.

Nakahashi M, Uei H, Hoshino M, Omori K, Igarashi H, Tokuhashi Y.

Pain Pract. 2020 Jan;20(1):55-61. doi: 10.1111/papr.12826. Epub 2019 Aug 28.

PMID:
31376336
18.

(R)-Ketamine Induces a Greater Increase in Prefrontal 5-HT Release Than (S)-Ketamine and Ketamine Metabolites via an AMPA Receptor-Independent Mechanism.

Ago Y, Tanabe W, Higuchi M, Tsukada S, Tanaka T, Yamaguchi T, Igarashi H, Yokoyama R, Seiriki K, Kasai A, Nakazawa T, Nakagawa S, Hashimoto K, Hashimoto H.

Int J Neuropsychopharmacol. 2019 Oct 1;22(10):665-674. doi: 10.1093/ijnp/pyz041.

19.

IL-6-PAD4 axis in the earliest phase of arthritis in knock-in gp130F759 mice, a model for rheumatoid arthritis.

Yahagi A, Saika T, Hirano H, Takai-Imamura M, Tsuji F, Aono H, Iseki M, Morita Y, Igarashi H, Saeki Y, Ishihara K.

RMD Open. 2019 Jun 21;5(2):e000853. doi: 10.1136/rmdopen-2018-000853. eCollection 2019.

20.

Whole hepatic lipid volume quantification and color mapping by multi-slice and multi-point magnetic resonance imaging.

Igarashi H, Shigiyama F, Wakui N, Nagai H, Shibuya K, Shiraga N, Hirose T, Kumashiro N.

Hepatol Res. 2019 Dec;49(12):1374-1385. doi: 10.1111/hepr.13408. Epub 2019 Aug 4.

PMID:
31313870
21.

The safety and preventive effects of a supraorbital transcutaneous stimulator in Japanese migraine patients.

Danno D, Iigaya M, Imai N, Igarashi H, Takeshima T.

Sci Rep. 2019 Jul 9;9(1):9900. doi: 10.1038/s41598-019-46044-8.

22.

Development of canine X-chromosome inactivation pattern analysis for the detection of cell clonality by incorporating the examination of the SLIT and NTRK-like family member 4 (SLITRK4) gene.

Tomita A, Mochizuki H, Tsuboi M, Ogura I, Igarashi H, Goto-Koshino Y, Takahashi M, Ohmi A, Tomiyasu H, Ohno K, Nakagawa T, Uchida K, Nishimura R, Tsujimoto H.

Res Vet Sci. 2019 Aug;125:170-175. doi: 10.1016/j.rvsc.2019.06.004. Epub 2019 Jun 11.

PMID:
31247472
23.

Factors Influencing Interbody Cage Subsidence Following Anterior Cervical Discectomy and Fusion.

Igarashi H, Hoshino M, Omori K, Matsuzaki H, Nemoto Y, Tsuruta T, Yamasaki K.

Clin Spine Surg. 2019 Aug;32(7):297-302. doi: 10.1097/BSD.0000000000000843.

PMID:
31169615
24.

Age-related analysis of the gut microbiome in a purebred dog colony.

Mizukami K, Uchiyama J, Igarashi H, Murakami H, Osumi T, Shima A, Ishiahra G, Nasukawa T, Une Y, Sakaguchi M.

FEMS Microbiol Lett. 2019 Apr 1;366(8). pii: fnz095. doi: 10.1093/femsle/fnz095.

PMID:
31049554
25.

Automaticity of pitch class-color synesthesia as revealed by a Stroop-like effect.

Itoh K, Sakata H, Igarashi H, Nakada T.

Conscious Cogn. 2019 May;71:86-91. doi: 10.1016/j.concog.2019.04.001. Epub 2019 Apr 9.

26.

Whole-brain block-face serial microscopy tomography at subcellular resolution using FAST.

Seiriki K, Kasai A, Nakazawa T, Niu M, Naka Y, Tanuma M, Igarashi H, Yamaura K, Hayata-Takano A, Ago Y, Hashimoto H.

Nat Protoc. 2019 May;14(5):1509-1529. doi: 10.1038/s41596-019-0148-4. Epub 2019 Apr 8.

PMID:
30962606
27.

The Japan Bioanalysis Forum (JBF): the past 8 years and future perspective.

Igarashi H, Koseki N, Arakawa T.

Bioanalysis. 2019 Apr;11(7):611-617. doi: 10.4155/bio-2019-0047. Epub 2019 Apr 4. No abstract available.

28.

Correction to: Phase II study of sunitinib in Japanese patients with unresectable or metastatic, well-differentiated pancreatic neuroendocrine tumor.

Ito T, Okusaka T, Nishida T, Yamao K, Igarashi H, Morizane C, Kondo S, Mizuno N, Hara K, Sawaki A, Hashigaki S, Kimura N, Murakami M, Ohki E, Chao RC, Imamura M.

Invest New Drugs. 2019 Jun;37(3):591. doi: 10.1007/s10637-019-00757-9.

29.

Visualizing the Distribution of Matrix Metalloproteinases in Ischemic Brain Using In Vivo 19F-Magnetic Resonance Spectroscopic Imaging.

Huber VJ, Igarashi H, Ueki S, Terumitsu-Tsujita M, Nito C, Ohno K, Suzuki Y, Itoh K, Kwee IL, Nakada T.

Contrast Media Mol Imaging. 2019 Jan 6;2019:8908943. doi: 10.1155/2019/8908943. eCollection 2019.

30.

Sustained fasting glucose oxidation and postprandial lipid oxidation associated with reduced insulin dose in type 2 diabetes with sodium-glucose cotransporter 2 inhibitor: A randomized, open-label, prospective study.

Kanazawa K, Uchino H, Shigiyama F, Igarashi H, Ikehara K, Yoshikawa F, Usui S, Miyagi M, Yoshino H, Ando Y, Kumashiro N, Hirose T.

J Diabetes Investig. 2019 Jul;10(4):1022-1031. doi: 10.1111/jdi.12994. Epub 2019 Feb 19.

31.

The Gα12/13-coupled receptor LPA4 limits proper adipose tissue expansion and remodeling in diet-induced obesity.

Yanagida K, Igarashi H, Yasuda D, Kobayashi D, Ohto-Nakanishi T, Akahoshi N, Sekiba A, Toyoda T, Ishijima T, Nakai Y, Shojima N, Kubota N, Abe K, Kadowaki T, Ishii S, Shimizu T.

JCI Insight. 2018 Dec 20;3(24). pii: 97293. doi: 10.1172/jci.insight.97293.

32.

Evaluation of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Intravenous Dose of Miridesap in Healthy Japanese Subjects.

Ino H, Doi Y, Liefaard L, Cookson L, Chen C, Itoh H, Igarashi H, Nakano A.

Clin Pharmacol Drug Dev. 2019 Jul;8(5):612-618. doi: 10.1002/cpdd.631. Epub 2018 Dec 17.

PMID:
30556959
33.

[Oculomotor nerve compression on MRI in a 56-year-old man with pituitary apoplexy due to panhypophisitis].

Igarashi H, Kokubun N, Funakoshi K, Sakurai S, Hirata K.

Rinsho Shinkeigaku. 2018 Nov 28;58(11):668-672. doi: 10.5692/clinicalneurol.cn-001192. Epub 2018 Oct 27. Review. Japanese.

PMID:
30369523
34.

Evaluation of the Safety, Tolerability, and Pharmacokinetics of GSK2269557 (Nemiralisib) Administered Via Dry Powder Inhaler to Healthy Japanese Subjects.

Ino H, Wilson R, Terao T, Ogura H, Igarashi H, Cahn A, Numachi Y.

Clin Pharmacol Drug Dev. 2019 Jan;8(1):78-86. doi: 10.1002/cpdd.614. Epub 2018 Oct 10.

PMID:
30303626
35.

Chronic intestinal pseudo-obstruction due to al amyloidosis: a case report and literature review.

Iida T, Hirayama D, Sudo G, Mitsuhashi K, Igarashi H, Yamashita K, Yamano H, Nakase H.

Clin J Gastroenterol. 2019 Apr;12(2):176-181. doi: 10.1007/s12328-018-0909-6. Epub 2018 Sep 19. Review.

PMID:
30232705
36.

The ninth Japan Bioanalysis Forum symposium.

Komaba J, Hosogi J, Igarashi H, Kamimori H, Nakai K, Nakamura T, Kawai Y, Sano Y, Yamaguchi T.

Bioanalysis. 2018 Sep 1;10(18):1467-1471. doi: 10.4155/bio-2018-0198. Epub 2018 Sep 10.

37.

Organelle Optogenetics: Direct Manipulation of Intracellular Ca2+ Dynamics by Light.

Asano T, Igarashi H, Ishizuka T, Yawo H.

Front Neurosci. 2018 Aug 17;12:561. doi: 10.3389/fnins.2018.00561. eCollection 2018.

38.

Watt-level 193 nm source generation based on compact collinear cascaded sum frequency mixing configuration.

Zhao Z, Qu C, Igarashi H, Xuan H, Miura T, Ito S, Kobayashi Y.

Opt Express. 2018 Jul 23;26(15):19435-19444. doi: 10.1364/OE.26.019435.

PMID:
30114115
39.

Mechanisms of sleep deprivation-induced hepatic steatosis and insulin resistance in mice.

Shigiyama F, Kumashiro N, Tsuneoka Y, Igarashi H, Yoshikawa F, Kakehi S, Funato H, Hirose T.

Am J Physiol Endocrinol Metab. 2018 Nov 1;315(5):E848-E858. doi: 10.1152/ajpendo.00072.2018. Epub 2018 Jul 10.

40.

MicroRNA-31 reflects IL-6 expression in cancer tissue and is related with poor prognosis in bile duct cancer.

Ishigami K, Nosho K, Koide H, Kanno S, Mitsuhashi K, Igarashi H, Shitani M, Motoya M, Kimura Y, Hasegawa T, Kaneto H, Takemasa I, Suzuki H, Nakase H.

Carcinogenesis. 2018 Sep 21;39(9):1127-1134. doi: 10.1093/carcin/bgy075.

PMID:
29860474
41.

Rare urogenital anomaly variant with a separated didelphic uterus and ipsilateral renal agenesis without hemivagina: A case report.

Watanabe N, Igarashi H, Matsukawa J, Matsuo K, Nagase S.

Congenit Anom (Kyoto). 2019 Mar;59(2):47-48. doi: 10.1111/cga.12290. Epub 2018 Jun 20. No abstract available.

PMID:
29845695
42.

Sox17 is essential for proper formation of the marginal zone of extraembryonic endoderm adjacent to a developing mouse placental disk.

Igarashi H, Uemura M, Hiramatsu R, Hiramatsu R, Segami S, Pattarapanawan M, Hirate Y, Yoshimura Y, Hashimoto H, Higashiyama H, Sumitomo H, Kurohmaru M, Saijoh Y, Suemizu H, Kanai-Azuma M, Kanai Y.

Biol Reprod. 2018 Sep 1;99(3):578-589. doi: 10.1093/biolre/ioy079.

43.

Targeted expression of step-function opsins in transgenic rats for optogenetic studies.

Igarashi H, Ikeda K, Onimaru H, Kaneko R, Koizumi K, Beppu K, Nishizawa K, Takahashi Y, Kato F, Matsui K, Kobayashi K, Yanagawa Y, Muramatsu SI, Ishizuka T, Yawo H.

Sci Rep. 2018 Apr 3;8(1):5435. doi: 10.1038/s41598-018-23810-8.

44.

An Advanced Well-differentiated Pancreatic Neuroendocrine Carcinoma (NET-G3) Associated with Von Hippel-Lindau Disease.

Miki M, Kawabe K, Igarashi H, Abe T, Ohishi Y, Hashimoto R, Karashima T, Yamasaki I, Inoue K, Ito T, Ogawa Y.

Intern Med. 2018 Jul 15;57(14):2007-2011. doi: 10.2169/internalmedicine.0416-17. Epub 2018 Feb 28.

45.

Aquaporin-4 facilitator TGN-073 promotes interstitial fluid circulation within the blood-brain barrier: [17O]H2O JJVCPE MRI study.

Huber VJ, Igarashi H, Ueki S, Kwee IL, Nakada T.

Neuroreport. 2018 Jun 13;29(9):697-703. doi: 10.1097/WNR.0000000000000990.

46.

The Development of Wisdom: A Social Ecological Approach.

Igarashi H, Levenson MR, Aldwin CM.

J Gerontol B Psychol Sci Soc Sci. 2018 Oct 10;73(8):1350-1358. doi: 10.1093/geronb/gby002.

PMID:
29425324
47.

Usefulness of acceleration time ratio in diagnosis of internal carotid artery origin stenosis.

Nishihira T, Takekawa H, Suzuki K, Suzuki A, Tsukahara Y, Iizuka K, Igarashi H, Iwasaki A, Okamura M, Hirata K.

J Med Ultrason (2001). 2018 Jul;45(3):493-500. doi: 10.1007/s10396-018-0863-4. Epub 2018 Jan 31.

48.

Long-term clinical outcomes of testicular sperm extraction and intracytoplasmic sperm injection for infertile men.

Okuyama N, Obata R, Oka N, Nakamura Y, Hattori H, Nakajo Y, Aono N, Koizumi M, Toya M, Nagao K, Tai T, Hashimoto T, Igarashi H, Kyono K.

Reprod Med Biol. 2017 Dec 1;17(1):82-88. doi: 10.1002/rmb2.12073. eCollection 2018 Jan.

49.

Compensatory mechanism of the spine after corrective surgery without lumbar-sacral fixation for traumatic thoracolumbar kyphotic spine deformity.

Matsumoto K, Hoshino M, Omori K, Igarashi H, Tsuruta T, Yamasaki K, Matsuzaki H, Iriuchishima T, Tokuhashi Y.

J Orthop Sci. 2018 Mar;23(2):253-257. doi: 10.1016/j.jos.2017.12.007. Epub 2018 Jan 6.

PMID:
29317155
50.

Evaluation of Bioequivalence Between 0.5-mg Dutasteride Capsules Manufactured by GlaxoSmithKline and an Existing Formulation: A Randomized Study in Healthy Japanese Male Volunteers.

Ino H, Itoh H, Doi Y, Igarashi H, Numachi Y.

Clin Pharmacol Drug Dev. 2018 Mar;7(3):341-346. doi: 10.1002/cpdd.407. Epub 2017 Dec 28. No abstract available.

PMID:
29283507

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