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Items: 25

1.

Carbon monoxide negatively regulates NLRP3 inflammasome activation in macrophages.

Jung SS, Moon JS, Xu JF, Ifedigbo E, Ryter SW, Choi AM, Nakahira K.

Am J Physiol Lung Cell Mol Physiol. 2015 May 15;308(10):L1058-67. doi: 10.1152/ajplung.00400.2014. Epub 2015 Mar 13.

2.

Circadian rhythm reprogramming during lung inflammation.

Haspel JA, Chettimada S, Shaik RS, Chu JH, Raby BA, Cernadas M, Carey V, Process V, Hunninghake GM, Ifedigbo E, Lederer JA, Englert J, Pelton A, Coronata A, Fredenburgh LE, Choi AM.

Nat Commun. 2014 Sep 11;5:4753. doi: 10.1038/ncomms5753.

3.

c-Kit-positive cardiac stem cells nested in hypoxic niches are activated by stem cell factor reversing the aging myopathy.

Sanada F, Kim J, Czarna A, Chan NY, Signore S, Ogórek B, Isobe K, Wybieralska E, Borghetti G, Pesapane A, Sorrentino A, Mangano E, Cappetta D, Mangiaracina C, Ricciardi M, Cimini M, Ifedigbo E, Perrella MA, Goichberg P, Choi AM, Kajstura J, Hosoda T, Rota M, Anversa P, Leri A.

Circ Res. 2014 Jan 3;114(1):41-55. doi: 10.1161/CIRCRESAHA.114.302500. Epub 2013 Oct 29. Erratum in: Circ Res. 2015 Jul 31;117(4):e54.

4.

TLR4 deficiency promotes autophagy during cigarette smoke-induced pulmonary emphysema.

An CH, Wang XM, Lam HC, Ifedigbo E, Washko GR, Ryter SW, Choi AM.

Am J Physiol Lung Cell Mol Physiol. 2012 Nov 1;303(9):L748-57. doi: 10.1152/ajplung.00102.2012. Epub 2012 Sep 14.

5.

Characterization of macroautophagic flux in vivo using a leupeptin-based assay.

Haspel J, Shaik RS, Ifedigbo E, Nakahira K, Dolinay T, Englert JA, Choi AM.

Autophagy. 2011 Jun;7(6):629-42. Epub 2011 Jun 1.

6.

Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema.

Chen ZH, Lam HC, Jin Y, Kim HP, Cao J, Lee SJ, Ifedigbo E, Parameswaran H, Ryter SW, Choi AM.

Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18880-5. doi: 10.1073/pnas.1005574107. Epub 2010 Oct 18.

7.

Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension.

Lee SJ, Smith A, Guo L, Alastalo TP, Li M, Sawada H, Liu X, Chen ZH, Ifedigbo E, Jin Y, Feghali-Bostwick C, Ryter SW, Kim HP, Rabinovitch M, Choi AM.

Am J Respir Crit Care Med. 2011 Mar 1;183(5):649-58. doi: 10.1164/rccm.201005-0746OC. Epub 2010 Oct 1.

8.

Nitrite potently inhibits hypoxic and inflammatory pulmonary arterial hypertension and smooth muscle proliferation via xanthine oxidoreductase-dependent nitric oxide generation.

Zuckerbraun BS, Shiva S, Ifedigbo E, Mathier MA, Mollen KP, Rao J, Bauer PM, Choi JJ, Curtis E, Choi AM, Gladwin MT.

Circulation. 2010 Jan 5;121(1):98-109. doi: 10.1161/CIRCULATIONAHA.109.891077. Epub 2009 Dec 21.

PMID:
20026772
9.

Deletion of caveolin-1 protects hyperoxia-induced apoptosis via survivin-mediated pathways.

Zhang M, Lin L, Lee SJ, Mo L, Cao J, Ifedigbo E, Jin Y.

Am J Physiol Lung Cell Mol Physiol. 2009 Nov;297(5):L945-53. doi: 10.1152/ajplung.00081.2009. Epub 2009 Sep 18.

10.

Carbon monoxide prevents ventilator-induced lung injury via caveolin-1.

Hoetzel A, Schmidt R, Vallbracht S, Goebel U, Dolinay T, Kim HP, Ifedigbo E, Ryter SW, Choi AM.

Crit Care Med. 2009 May;37(5):1708-15. doi: 10.1097/CCM.0b013e31819efa31.

11.

Caveolin-1 regulates the secretion and cytoprotection of Cyr61 in hyperoxic cell death.

Jin Y, Kim HP, Cao J, Zhang M, Ifedigbo E, Choi AM.

FASEB J. 2009 Feb;23(2):341-50. doi: 10.1096/fj.08-108423. Epub 2008 Sep 18.

12.

Carbon monoxide protects against ventilator-induced lung injury via PPAR-gamma and inhibition of Egr-1.

Hoetzel A, Dolinay T, Vallbracht S, Zhang Y, Kim HP, Ifedigbo E, Alber S, Kaynar AM, Schmidt R, Ryter SW, Choi AM.

Am J Respir Crit Care Med. 2008 Jun 1;177(11):1223-32. doi: 10.1164/rccm.200708-1265OC. Epub 2008 Mar 20.

13.

Protein kinase C alpha and zeta differentially regulate death-inducing signaling complex formation in cigarette smoke extract-induced apoptosis.

Park JW, Kim HP, Lee SJ, Wang X, Wang Y, Ifedigbo E, Watkins SC, Ohba M, Ryter SW, Vyas YM, Choi AM.

J Immunol. 2008 Apr 1;180(7):4668-78.

14.

Deletion of caveolin-1 protects against oxidative lung injury via up-regulation of heme oxygenase-1.

Jin Y, Kim HP, Chi M, Ifedigbo E, Ryter SW, Choi AM.

Am J Respir Cell Mol Biol. 2008 Aug;39(2):171-9. doi: 10.1165/rcmb.2007-0323OC. Epub 2008 Mar 6.

15.

Mitogen-activated protein kinases regulate susceptibility to ventilator-induced lung injury.

Dolinay T, Wu W, Kaminski N, Ifedigbo E, Kaynar AM, Szilasi M, Watkins SC, Ryter SW, Hoetzel A, Choi AM.

PLoS One. 2008 Feb 13;3(2):e1601. doi: 10.1371/journal.pone.0001601.

16.

Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis.

Wang XM, Zhang Y, Kim HP, Zhou Z, Feghali-Bostwick CA, Liu F, Ifedigbo E, Xu X, Oury TD, Kaminski N, Choi AM.

J Exp Med. 2006 Dec 25;203(13):2895-906. Epub 2006 Dec 18.

17.

Carbon monoxide reverses established pulmonary hypertension.

Zuckerbraun BS, Chin BY, Wegiel B, Billiar TR, Czsimadia E, Rao J, Shimoda L, Ifedigbo E, Kanno S, Otterbein LE.

J Exp Med. 2006 Sep 4;203(9):2109-19. Epub 2006 Aug 14.

18.

Inhaled carbon monoxide inhibits intimal hyperplasia and provides added benefit with nitric oxide.

Raman KG, Barbato JE, Ifedigbo E, Ozanich BA, Zenati MS, Otterbein LE, Tzeng E.

J Vasc Surg. 2006 Jul;44(1):151-8.

19.

Carbon monoxide orchestrates a protective response through PPARgamma.

Bilban M, Bach FH, Otterbein SL, Ifedigbo E, d'Avila JC, Esterbauer H, Chin BY, Usheva A, Robson SC, Wagner O, Otterbein LE.

Immunity. 2006 May;24(5):601-10.

20.

Cyr61 protects against hyperoxia-induced cell death via Akt pathway in pulmonary epithelial cells.

Jin Y, Kim HP, Ifedigbo E, Lau LF, Choi AM.

Am J Respir Cell Mol Biol. 2005 Sep;33(3):297-302. Epub 2005 Jun 16.

PMID:
15961723
21.

Brief inhalation of low-dose carbon monoxide protects rodents and swine from postoperative ileus.

Moore BA, Overhaus M, Whitcomb J, Ifedigbo E, Choi AM, Otterbein LE, Bauer AJ.

Crit Care Med. 2005 Jun;33(6):1317-26.

PMID:
15942350
22.

Carbon monoxide prevents multiple organ injury in a model of hemorrhagic shock and resuscitation.

Zuckerbraun BS, McCloskey CA, Gallo D, Liu F, Ifedigbo E, Otterbein LE, Billiar TR.

Shock. 2005 Jun;23(6):527-32.

PMID:
15897805
23.

Carbon monoxide protection against endotoxic shock involves reciprocal effects on iNOS in the lung and liver.

Sarady JK, Zuckerbraun BS, Bilban M, Wagner O, Usheva A, Liu F, Ifedigbo E, Zamora R, Choi AM, Otterbein LE.

FASEB J. 2004 May;18(7):854-6. Epub 2004 Mar 4.

PMID:
15001560
24.

Heme oxygenase-1-derived carbon monoxide protects hearts from transplant associated ischemia reperfusion injury.

Akamatsu Y, Haga M, Tyagi S, Yamashita K, Graça-Souza AV, Ollinger R, Czismadia E, May GA, Ifedigbo E, Otterbein LE, Bach FH, Soares MP.

FASEB J. 2004 Apr;18(6):771-2. Epub 2004 Feb 20. Erratum in: FASEB J. 2004 Jul;18(10):1168.

PMID:
14977880
25.

MKK3 mitogen-activated protein kinase pathway mediates carbon monoxide-induced protection against oxidant-induced lung injury.

Otterbein LE, Otterbein SL, Ifedigbo E, Liu F, Morse DE, Fearns C, Ulevitch RJ, Knickelbein R, Flavell RA, Choi AM.

Am J Pathol. 2003 Dec;163(6):2555-63.

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