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Items: 33

1.

Comprehensive Multiple eQTL Detection and Its Application to GWAS Interpretation.

Zeng B, Lloyd-Jones LR, Montgomery GW, Metspalu A, Esko T, Franke L, Vosa U, Claringbould A, Brigham KL, Quyyumi AA, Idaghdour Y, Yang J, Visscher PM, Powell JE, Gibson G.

Genetics. 2019 May 22. pii: genetics.302091.2019. doi: 10.1534/genetics.119.302091. [Epub ahead of print]

2.

Differential regulation of Ca2+ influx by ORAI channels mediates enamel mineralization.

Eckstein M, Vaeth M, Aulestia FJ, Costiniti V, Kassam SN, Bromage TG, Pedersen P, Issekutz T, Idaghdour Y, Moursi AM, Feske S, Lacruz RS.

Sci Signal. 2019 Apr 23;12(578). pii: eaav4663. doi: 10.1126/scisignal.aav4663.

PMID:
31015290
3.

Gene-by-environment interactions in urban populations modulate risk phenotypes.

Favé MJ, Lamaze FC, Soave D, Hodgkinson A, Gauvin H, Bruat V, Grenier JC, Gbeha E, Skead K, Smargiassi A, Johnson M, Idaghdour Y, Awadalla P.

Nat Commun. 2018 Mar 6;9(1):827. doi: 10.1038/s41467-018-03202-2.

4.

Constraints on eQTL Fine Mapping in the Presence of Multisite Local Regulation of Gene Expression.

Zeng B, Lloyd-Jones LR, Holloway A, Marigorta UM, Metspalu A, Montgomery GW, Esko T, Brigham KL, Quyyumi AA, Idaghdour Y, Yang J, Visscher PM, Powell JE, Gibson G.

G3 (Bethesda). 2017 Aug 7;7(8):2533-2544. doi: 10.1534/g3.117.043752.

5.

Integrated genomic analysis of mitochondrial RNA processing in human cancers.

Idaghdour Y, Hodgkinson A.

Genome Med. 2017 Apr 18;9(1):36. doi: 10.1186/s13073-017-0426-0.

6.

Store-operated Ca2+ entry controls ameloblast cell function and enamel development.

Eckstein M, Vaeth M, Fornai C, Vinu M, Bromage TG, Nurbaeva MK, Sorge JL, Coelho PG, Idaghdour Y, Feske S, Lacruz RS.

JCI Insight. 2017 Mar 23;2(6):e91166. doi: 10.1172/jci.insight.91166.

7.

Inhibition of DNA and Histone Methylation by 5-Aza-2'-Deoxycytidine (Decitabine) and 3-Deazaneplanocin-A on Antineoplastic Action and Gene Expression in Myeloid Leukemic Cells.

Momparler RL, Côté S, Momparler LF, Idaghdour Y.

Front Oncol. 2017 Feb 15;7:19. doi: 10.3389/fonc.2017.00019. eCollection 2017.

8.

Comparative Analysis of Iron Homeostasis in Sub-Saharan African Children with Sickle Cell Disease and Their Unaffected Siblings.

Gomez S, Diawara A, Gbeha E, Awadalla P, Sanni A, Idaghdour Y, Rahimy MC.

Front Pediatr. 2016 Feb 23;4:8. doi: 10.3389/fped.2016.00008. eCollection 2016.

9.

The Swine Plasma Metabolome Chronicles "Many Days" Biological Timing and Functions Linked to Growth.

Bromage TG, Idaghdour Y, Lacruz RS, Crenshaw TD, Ovsiy O, Rotter B, Hoffmeier K, Schrenk F.

PLoS One. 2016 Jan 6;11(1):e0145919. doi: 10.1371/journal.pone.0145919. eCollection 2016.

10.

Levels of genetic diversity and taxonomic status of Epinephelus species in United Arab Emirates fish markets.

Ketchum RN, Dieng MM, Vaughan GO, Burt JA, Idaghdour Y.

Mar Pollut Bull. 2016 Apr 30;105(2):540-5. doi: 10.1016/j.marpolbul.2015.11.042. Epub 2015 Dec 3.

PMID:
26656801
11.

Whole genome re-sequencing of date palms yields insights into diversification of a fruit tree crop.

Hazzouri KM, Flowers JM, Visser HJ, Khierallah HSM, Rosas U, Pham GM, Meyer RS, Johansen CK, Fresquez ZA, Masmoudi K, Haider N, El Kadri N, Idaghdour Y, Malek JA, Thirkhill D, Markhand GS, Krueger RR, Zaid A, Purugganan MD.

Nat Commun. 2015 Nov 9;6:8824. doi: 10.1038/ncomms9824.

12.

Recombination affects accumulation of damaging and disease-associated mutations in human populations.

Hussin JG, Hodgkinson A, Idaghdour Y, Grenier JC, Goulet JP, Gbeha E, Hip-Ki E, Awadalla P.

Nat Genet. 2015 Apr;47(4):400-4. doi: 10.1038/ng.3216. Epub 2015 Feb 16.

PMID:
25685891
13.

Epigenetic therapy of acute myeloid leukemia using 5-aza-2'-deoxycytidine (decitabine) in combination with inhibitors of histone methylation and deacetylation.

Momparler RL, Côté S, Momparler LF, Idaghdour Y.

Clin Epigenetics. 2014 Oct 1;6(1):19. doi: 10.1186/1868-7083-6-19. eCollection 2014.

14.

High-resolution genomic analysis of human mitochondrial RNA sequence variation.

Hodgkinson A, Idaghdour Y, Gbeha E, Grenier JC, Hip-Ki E, Bruat V, Goulet JP, de Malliard T, Awadalla P.

Science. 2014 Apr 25;344(6182):413-5. doi: 10.1126/science.1251110.

15.

Genomic architecture of sickle cell disease in West African children.

Quinlan J, Idaghdour Y, Goulet JP, Gbeha E, de Malliard T, Bruat V, Grenier JC, Gomez S, Sanni A, Rahimy MC, Awadalla P.

Front Genet. 2014 Feb 14;5:26. doi: 10.3389/fgene.2014.00026. eCollection 2014.

16.

Whole-exome sequencing reveals a rapid change in the frequency of rare functional variants in a founding population of humans.

Casals F, Hodgkinson A, Hussin J, Idaghdour Y, Bruat V, de Maillard T, Grenier JC, Gbeha E, Hamdan FF, Girard S, Spinella JF, Larivière M, Saillour V, Healy J, Fernández I, Sinnett D, Michaud JL, Rouleau GA, Haddad E, Le Deist F, Awadalla P.

PLoS Genet. 2013;9(9):e1003815. doi: 10.1371/journal.pgen.1003815. Epub 2013 Sep 26. Erratum in: PLoS Genet. 2014 Feb;10(2):e1004260. Grenier, Jean-Cristophe [corrected to Grenier, Jean-Christophe].

17.

Selective constraint, background selection, and mutation accumulation variability within and between human populations.

Hodgkinson A, Casals F, Idaghdour Y, Grenier JC, Hernandez RD, Awadalla P.

BMC Genomics. 2013 Jul 23;14:495. doi: 10.1186/1471-2164-14-495.

18.

Association between response to albendazole treatment and β-tubulin genotype frequencies in soil-transmitted helminths.

Diawara A, Halpenny CM, Churcher TS, Mwandawiro C, Kihara J, Kaplan RM, Streit TG, Idaghdour Y, Scott ME, Basáñez MG, Prichard RK.

PLoS Negl Trop Dis. 2013 May 30;7(5):e2247. doi: 10.1371/journal.pntd.0002247. Print 2013.

19.

Blood-informative transcripts define nine common axes of peripheral blood gene expression.

Preininger M, Arafat D, Kim J, Nath AP, Idaghdour Y, Brigham KL, Gibson G.

PLoS Genet. 2013;9(3):e1003362. doi: 10.1371/journal.pgen.1003362. Epub 2013 Mar 14.

20.

Exome sequencing identifies mutations in the gene TTC7A in French-Canadian cases with hereditary multiple intestinal atresia.

Samuels ME, Majewski J, Alirezaie N, Fernandez I, Casals F, Patey N, Decaluwe H, Gosselin I, Haddad E, Hodgkinson A, Idaghdour Y, Marchand V, Michaud JL, Rodrigue MA, Desjardins S, Dubois S, Le Deist F, Awadalla P, Raymond V, Maranda B.

J Med Genet. 2013 May;50(5):324-9. doi: 10.1136/jmedgenet-2012-101483. Epub 2013 Feb 19.

21.

Rare allelic forms of PRDM9 associated with childhood leukemogenesis.

Hussin J, Sinnett D, Casals F, Idaghdour Y, Bruat V, Saillour V, Healy J, Grenier JC, de Malliard T, Busche S, Spinella JF, Larivière M, Gibson G, Andersson A, Holmfeldt L, Ma J, Wei L, Zhang J, Andelfinger G, Downing JR, Mullighan CG, Awadalla P.

Genome Res. 2013 Mar;23(3):419-30. doi: 10.1101/gr.144188.112. Epub 2012 Dec 5.

22.

Cohort profile of the CARTaGENE study: Quebec's population-based biobank for public health and personalized genomics.

Awadalla P, Boileau C, Payette Y, Idaghdour Y, Goulet JP, Knoppers B, Hamet P, Laberge C; CARTaGENE Project.

Int J Epidemiol. 2013 Oct;42(5):1285-99. doi: 10.1093/ije/dys160. Epub 2012 Oct 15.

PMID:
23071140
23.

Rare copy number variants contribute to congenital left-sided heart disease.

Hitz MP, Lemieux-Perreault LP, Marshall C, Feroz-Zada Y, Davies R, Yang SW, Lionel AC, D'Amours G, Lemyre E, Cullum R, Bigras JL, Thibeault M, Chetaille P, Montpetit A, Khairy P, Overduin B, Klaassen S, Hoodless P, Awadalla P, Hussin J, Idaghdour Y, Nemer M, Stewart AF, Boerkoel C, Scherer SW, Richter A, Dubé MP, Andelfinger G.

PLoS Genet. 2012 Sep;8(9):e1002903. doi: 10.1371/journal.pgen.1002903. Epub 2012 Sep 6. Erratum in: PLoS Genet. 2013 Mar;9(3). doi: 10.1371/annotation/8bc63544-9ed4-42ca-a830-e8058ab13bab. Awadalla, Philip [added]; Hussin, Julie [added]; Idaghdour, Youssef [added].

24.

Evidence for additive and interaction effects of host genotype and infection in malaria.

Idaghdour Y, Quinlan J, Goulet JP, Berghout J, Gbeha E, Bruat V, de Malliard T, Grenier JC, Gomez S, Gros P, Rahimy MC, Sanni A, Awadalla P.

Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16786-93. doi: 10.1073/pnas.1204945109. Epub 2012 Sep 4.

25.

Synergistic antileukemic action of a combination of inhibitors of DNA methylation and histone methylation.

Momparler RL, Idaghdour Y, Marquez VE, Momparler LF.

Leuk Res. 2012 Aug;36(8):1049-54. doi: 10.1016/j.leukres.2012.03.001. Epub 2012 Apr 1.

26.

Next-generation sequencing approaches for genetic mapping of complex diseases.

Casals F, Idaghdour Y, Hussin J, Awadalla P.

J Neuroimmunol. 2012 Jul 15;248(1-2):10-22. doi: 10.1016/j.jneuroim.2011.12.017. Epub 2012 Jan 27. Review.

PMID:
22285396
27.

Exploiting gene expression variation to capture gene-environment interactions for disease.

Idaghdour Y, Awadalla P.

Front Genet. 2013 May 31;3:228. doi: 10.3389/fgene.2012.00228. eCollection 2012.

28.

Variation in genome-wide mutation rates within and between human families.

Conrad DF, Keebler JE, DePristo MA, Lindsay SJ, Zhang Y, Casals F, Idaghdour Y, Hartl CL, Torroja C, Garimella KV, Zilversmit M, Cartwright R, Rouleau GA, Daly M, Stone EA, Hurles ME, Awadalla P; 1000 Genomes Project.

Nat Genet. 2011 Jun 12;43(7):712-4. doi: 10.1038/ng.862.

29.

The effects of weak genetic perturbations on the transcriptome of the wing imaginal disc and its association with wing shape in Drosophila melanogaster.

Dworkin I, Anderson JA, Idaghdour Y, Parker EK, Stone EA, Gibson G.

Genetics. 2011 Apr;187(4):1171-84. doi: 10.1534/genetics.110.125922. Epub 2011 Feb 1.

30.

Geographical genomics of human leukocyte gene expression variation in southern Morocco.

Idaghdour Y, Czika W, Shianna KV, Lee SH, Visscher PM, Martin HC, Miclaus K, Jadallah SJ, Goldstein DB, Wolfinger RD, Gibson G.

Nat Genet. 2010 Jan;42(1):62-7. doi: 10.1038/ng.495. Epub 2009 Dec 6.

31.

Pharmacogenetic association study of 30 genes with phenobarbital drug response in epileptic dogs.

Kennerly EM, Idaghdour Y, Olby NJ, Munana KR, Gibson G.

Pharmacogenet Genomics. 2009 Dec;19(12):911-22. doi: 10.1097/FPC.0b013e3283307cba.

PMID:
19841609
32.

A genome-wide gene expression signature of environmental geography in leukocytes of Moroccan Amazighs.

Idaghdour Y, Storey JD, Jadallah SJ, Gibson G.

PLoS Genet. 2008 Apr 11;4(4):e1000052. doi: 10.1371/journal.pgen.1000052.

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