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Increase in circulating ACE-positive endothelial microparticles during acute lung injury.

Takei Y, Yamada M, Saito K, Kameyama Y, Sugiura H, Makiguchi T, Fujino N, Koarai A, Toyama H, Saito K, Ejima Y, Kawazoe Y, Kudo D, Kushimoto S, Yamauchi M, Ichinose M.

Eur Respir J. 2019 Jul 18. pii: 1801188. doi: 10.1183/13993003.01188-2018. [Epub ahead of print]


Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases.

Fujino N, Brand OJ, Morgan DJ, Fujimori T, Grabiec AM, Jagger CP, Maciewicz RA, Yamada M, Itakura K, Sugiura H, Ichinose M, Hussell T.

J Exp Med. 2019 Jul 9. pii: jem.20171978. doi: 10.1084/jem.20171978. [Epub ahead of print]


Protein C and protein S deficiencies may be related to survival among hemodialysis patients.

Ichinose M, Sasagawa N, Chiba T, Toyama K, Kayamori Y, Kang D.

BMC Nephrol. 2019 May 28;20(1):191. doi: 10.1186/s12882-019-1344-8.


Nitrosative stress in patients with asthma-chronic obstructive pulmonary disease overlap.

Kyogoku Y, Sugiura H, Ichikawa T, Numakura T, Koarai A, Yamada M, Fujino N, Tojo Y, Onodera K, Tanaka R, Sato K, Sano H, Yamanaka S, Itakura K, Mitsune A, Tamada T, Akaike T, Ichinose M.

J Allergy Clin Immunol. 2019 May 9. pii: S0091-6749(19)30609-8. doi: 10.1016/j.jaci.2019.04.023. [Epub ahead of print]


Cardiac injury due to the rapid progress of the dislocation of rib fractures: A rare case that required urgent open reduction and internal rib fixation.

Okamoto K, Ueda K, Ichinose M.

Respir Med Case Rep. 2019 Apr 16;27:100840. doi: 10.1016/j.rmcr.2019.100840. eCollection 2019.


Low- and high-dose aripiprazole augmentation and plasma levels of homovanillic acid in major depressive disorder: A randomized, open-label study.

Horikoshi S, Miura I, Ichinose M, Yamamoto S, Ito M, Watanabe K, Kanno-Nozaki K, Kaneko H, Yabe H.

Hum Psychopharmacol. 2019 May;34(3):e2696. doi: 10.1002/hup.2696. Epub 2019 May 1.


Mathematical modeling for the prediction of cerebral white matter lesions based on clinical examination data.

Shinkawa Y, Yoshida T, Onaka Y, Ichinose M, Ishii K.

PLoS One. 2019 Apr 16;14(4):e0215142. doi: 10.1371/journal.pone.0215142. eCollection 2019.


Decoupling of spontaneous facial mimicry from emotion recognition in schizophrenia.

Torregrossa LJ, Bian D, Wade J, Adery LH, Ichinose M, Nichols H, Bekele E, Sarkar N, Park S.

Psychiatry Res. 2019 May;275:169-176. doi: 10.1016/j.psychres.2019.03.035. Epub 2019 Mar 20.


Significance of a Family-based Study of Hereditary Thrombosis: A Single-family Case Series of Protein C Deficiency.

Ichinose M, Kasai K, Kayamori Y, Hamasaki N.

Intern Med. 2019 Jul 1;58(13):1923-1928. doi: 10.2169/internalmedicine.2308-18. Epub 2019 Mar 28.


Prognostic Factors of Malignant Peritoneal Mesothelioma Experienced in Japanese Peritoneal Metastasis Center.

Yonemura Y, Canbay E, Wakama S, Sako S, Ishibashi H, Hirano M, Motoi S, Mizumoto A, Takao N, Ichinose M, Noguchi K, Liu Y, Fushida S.

Gan To Kagaku Ryoho. 2019 Feb;46(2):395-399.


Analysis of Treatment Failure after Complete Cytoreductive Surgery for Peritoneal Metastasis from Appendiceal Mucinous Neoplasm at a Japanese High Volume Center for Peritoneal Surface Malignancy.

Yonemura Y, Canbay E, Wakama S, Sako S, Ishibashi H, Hirano M, Motoi S, Mizumoto A, Takao N, Ichinose M, Noguchi K, Liu Y, Fushida S, Li Y.

Gan To Kagaku Ryoho. 2019 Feb;46(2):251-258.


History of Peritoneal Surface Malignancy Treatment in Japan.

Yonemura Y, Sako S, Wakama S, Ishibashi H, Mizumoto A, Takao N, Ichinose M, Noguchi K, Liu Y, Motoi S, Taniguchi K, Fushida S.

Indian J Surg Oncol. 2019 Feb;10(Suppl 1):3-11. doi: 10.1007/s13193-019-00893-x. Epub 2019 Feb 19. Review.


Traumatic hemothorax due to chance fracture requiring emergency surgical management: A report of two cases.

Okamoto K, Ichinose M, Hanaoka J.

SAGE Open Med Case Rep. 2018 Dec 20;6:2050313X18819617. doi: 10.1177/2050313X18819617. eCollection 2018.


Axl kinase drives immune checkpoint and chemokine signalling pathways in lung adenocarcinomas.

Tsukita Y, Fujino N, Miyauchi E, Saito R, Fujishima F, Itakura K, Kyogoku Y, Okutomo K, Yamada M, Okazaki T, Sugiura H, Inoue A, Okada Y, Ichinose M.

Mol Cancer. 2019 Feb 11;18(1):24. doi: 10.1186/s12943-019-0953-y.


Effects of gene duplication, epistasis, recombination and gene conversion on the fixation time of compensatory mutations.

Kusumi J, Ichinose M, Iizuka M.

J Theor Biol. 2019 Apr 21;467:134-141. doi: 10.1016/j.jtbi.2019.02.001. Epub 2019 Feb 6.


Beneficial effects of sunitinib on tumor microenvironment and immunotherapy targeting death receptor5.

Tsukita Y, Okazaki T, Ebihara S, Komatsu R, Nihei M, Kobayashi M, Hirano T, Sugiura H, Tamada T, Tanaka N, Sato Y, Yagita H, Ichinose M.

Oncoimmunology. 2018 Nov 13;8(2):e1543526. doi: 10.1080/2162402X.2018.1543526. eCollection 2019.


Alpha-Blockers As Colorectal Cancer Chemopreventive: Findings from a Case-Control Study, Human Cell Cultures, and In Vivo Preclinical Testing.

Suzuki N, Niikura R, Ihara S, Hikiba Y, Kinoshita H, Higashishima N, Hayakawa Y, Yamada A, Hirata Y, Nakata R, Okamoto M, Sano M, Kushiyama A, Ichinose M, Woods SL, Worthley D, Iwamoto Y, Koike K.

Cancer Prev Res (Phila). 2019 Mar;12(3):185-194. doi: 10.1158/1940-6207.CAPR-18-0288. Epub 2019 Jan 30.


Extraction of Emotional Information via Visual Scanning Patterns: A Feasibility Study of Participants with Schizophrenia and Neurotypical Individuals.

Wade J, Nichols HS, Ichinose M, Bian D, Bekele E, Snodgress M, Amat AZ, Granholm E, Park S, Sarkar N.

ACM Trans Access Comput. 2018 Nov;11(4). pii: 23. doi: 10.1145/3282434.


Muscular blood flow responses as an early predictor of the severity of diabetic neuropathy at a later stage in streptozotocin-induced type I diabetic rats: a diffuse correlation spectroscopy study.

Ono Y, Esaki K, Takahashi Y, Nakabayashi M, Ichinose M, Lee K.

Biomed Opt Express. 2018 Aug 29;9(9):4539-4551. doi: 10.1364/BOE.9.004539. eCollection 2018 Sep 1.


Combination of assist use of short-acting beta-2 agonists inhalation and guidance based on patient-specific restrictions in daily behavior: Impact on physical activity of Japanese patients with chronic obstructive pulmonary disease.

Hirano T, Matsunaga K, Hamada K, Uehara S, Suetake R, Yamaji Y, Oishi K, Asami M, Edakuni N, Ogawa H, Ichinose M.

Respir Investig. 2019 Mar;57(2):133-139. doi: 10.1016/j.resinv.2018.12.001. Epub 2019 Jan 3.


Significant differences in T cell receptor repertoires in lung adenocarcinomas with and without epidermal growth factor receptor mutations.

Miyauchi E, Matsuda T, Kiyotani K, Low SK, Hsu YW, Tsukita Y, Ichinose M, Sakurada A, Okada Y, Saito R, Nakamura Y.

Cancer Sci. 2019 Mar;110(3):867-874. doi: 10.1111/cas.13919. Epub 2019 Feb 16.


The Cholinergic Pathways in Inflammation: A Potential Pharmacotherapeutic Target for COPD.

Yamada M, Ichinose M.

Front Pharmacol. 2018 Dec 3;9:1426. doi: 10.3389/fphar.2018.01426. eCollection 2018. Review.


The P-class pentatricopeptide repeat protein PpPPR_21 is needed for accumulation of the psbI-ycf12 dicistronic mRNA in Physcomitrella chloroplasts.

Ebihara T, Matsuda T, Sugita C, Ichinose M, Yamamoto H, Shikanai T, Sugita M.

Plant J. 2019 Mar;97(6):1120-1131. doi: 10.1111/tpj.14187. Epub 2019 Jan 18.


Nodular gastritis in association with gastric cancer development before and after Helicobacter pylori eradication.

Nishikawa I, Kato J, Terasoma S, Matsutani H, Tamaki H, Tamaki T, Kuwashima F, Nakata H, Tomeki T, Matsunaka H, Ibata Y, Yamashita Y, Maekita T, Higashi K, Ichinose M.

JGH Open. 2018 Mar 25;2(3):80-86. doi: 10.1002/jgh3.12049. eCollection 2018 Jun.


Identification of volatile metabolites in human saliva from patients with oral squamous cell carcinoma via zeolite-based thin-film microextraction coupled with GC-MS.

Shigeyama H, Wang T, Ichinose M, Ansai T, Lee SW.

J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Jan 1;1104:49-58. doi: 10.1016/j.jchromb.2018.11.002. Epub 2018 Nov 6.


Possible involvement of interleukin-18 in the pathology of hepatobiliary adverse effects related to treatment with ceritinib.

Hirano T, Koarai A, Ichikawa T, Sato T, Ohe T, Ichinose M.

BMC Cancer. 2018 Oct 19;18(1):995. doi: 10.1186/s12885-018-4913-5.


The acceptability and feasibility of a novel virtual reality based social skills training game for schizophrenia: Preliminary findings.

Adery LH, Ichinose M, Torregrossa LJ, Wade J, Nichols H, Bekele E, Bian D, Gizdic A, Granholm E, Sarkar N, Park S.

Psychiatry Res. 2018 Dec;270:496-502. doi: 10.1016/j.psychres.2018.10.014. Epub 2018 Oct 9.


Pulmonary Lymphatic Perfusion Syndrome.

Hirano T, Fujino N, Takase K, Ota H, Tanaka R, Saito R, Suzuki A, Okutomo K, Sato T, Kageyama S, Tamada T, Sugiura H, Ichinose M.

Am J Respir Crit Care Med. 2019 Feb 15;199(4):529-530. doi: 10.1164/rccm.201806-1125IM. No abstract available.


Triple therapy with budesonide/glycopyrrolate/formoterol fumarate with co-suspension delivery technology versus dual therapies in chronic obstructive pulmonary disease (KRONOS): a double-blind, parallel-group, multicentre, phase 3 randomised controlled trial.

Ferguson GT, Rabe KF, Martinez FJ, Fabbri LM, Wang C, Ichinose M, Bourne E, Ballal S, Darken P, DeAngelis K, Aurivillius M, Dorinsky P, Reisner C.

Lancet Respir Med. 2018 Oct;6(10):747-758. doi: 10.1016/S2213-2600(18)30327-8. Epub 2018 Sep 16. Erratum in: Lancet Respir Med. 2018 Oct 4;:. Lancet Respir Med. 2019 Feb;7(2):e9.


COPD uncovered: a cross-sectional study to assess the socioeconomic burden of COPD in Japan.

Igarashi A, Fukuchi Y, Hirata K, Ichinose M, Nagai A, Nishimura M, Yoshisue H, Ohara K, Gruenberger JB.

Int J Chron Obstruct Pulmon Dis. 2018 Aug 28;13:2629-2641. doi: 10.2147/COPD.S167476. eCollection 2018.


TLR7 agonist attenuates acetylcholine-induced, Ca2+ -dependent ionic currents in swine tracheal submucosal gland cells.

Gamo S, Tamada T, Murakami K, Muramatsu S, Aritake H, Nara M, Kazama I, Okazaki T, Sugiura H, Ichinose M.

Exp Physiol. 2018 Nov;103(11):1543-1559. doi: 10.1113/EP087221. Epub 2018 Oct 13.


Tiotropium/olodaterol versus tiotropium in Japanese patients with COPD: results from the DYNAGITO study.

Ichinose M, Nishimura M, Akimoto M, Kurotori Y, Zhao Y, de la Hoz A, Mishima M.

Int J Chron Obstruct Pulmon Dis. 2018 Jul 13;13:2147-2156. doi: 10.2147/COPD.S169941. eCollection 2018. Erratum in: Int J Chron Obstruct Pulmon Dis. 2018 Oct 30;13:3587.


Light-regulated PAS-containing histidine kinases delay gametophore formation in the moss Physcomitrella patens.

Ryo M, Yamashino T, Nomoto Y, Goto Y, Ichinose M, Sato K, Sugita M, Aoki S.

J Exp Bot. 2018 Sep 14;69(20):4839-4851. doi: 10.1093/jxb/ery257.


Expression of Gastric Markers Is Associated with Malignant Potential of Nonampullary Duodenal Adenocarcinoma.

Minatsuki C, Yamamichi N, Inada KI, Takahashi Y, Sakurai K, Shimamoto T, Tsuji Y, Shiogama K, Kodashima S, Sakaguchi Y, Niimi K, Ono S, Niwa T, Ohata K, Matsuhashi N, Ichinose M, Fujishiro M, Tsutsumi Y, Koike K.

Dig Dis Sci. 2018 Oct;63(10):2617-2625. doi: 10.1007/s10620-018-5179-0. Epub 2018 Jun 28.


Identification of marker genes and pathways specific to precancerous duodenal adenomas and early stage adenocarcinomas.

Sakaguchi Y, Yamamichi N, Tomida S, Takeuchi C, Kageyama-Yahara N, Takahashi Y, Shiogama K, Inada KI, Ichinose M, Fujishiro M, Koike K.

J Gastroenterol. 2019 Feb;54(2):131-140. doi: 10.1007/s00535-018-1489-4. Epub 2018 Jun 28.


Correction to: Oxidative stress enhances the expression of IL-33 in human airway epithelial cells.

Aizawa H, Koarai A, Shishikura Y, Yanagisawa S, Yamaya M, Sugiura H, Numakura T, Yamada M, Ichikawa T, Fujino N, Noda M, Okada Y, Ichinose M.

Respir Res. 2018 Jun 12;19(1):116. doi: 10.1186/s12931-018-0817-9.


Expression of cytochrome P450 mRNAs in Type II alveolar cells from subjects with chronic obstructive pulmonary disease.

Kamata S, Fujino N, Yamada M, Grime K, Suzuki S, Ota C, Tando Y, Okada Y, Sakurada A, Noda M, Matsuda Y, Sugiura H, Ichinose M.

Pharmacol Res Perspect. 2018 May 21;6(3):e00405. doi: 10.1002/prp2.405. eCollection 2018 Jun.


Aspiration pneumonia induces muscle atrophy in the respiratory, skeletal, and swallowing systems.

Komatsu R, Okazaki T, Ebihara S, Kobayashi M, Tsukita Y, Nihei M, Sugiura H, Niu K, Ebihara T, Ichinose M.

J Cachexia Sarcopenia Muscle. 2018 Aug;9(4):643-653. doi: 10.1002/jcsm.12297. Epub 2018 May 22.


The first case of multiple pulmonary granulomas with amyloid deposition in a dental technician; a rare manifestation as an occupational lung disease.

Hirano T, Numakura T, Moriyama H, Saito R, Shishikura Y, Shiihara J, Sugiura H, Ichinose M.

BMC Pulm Med. 2018 May 22;18(1):77. doi: 10.1186/s12890-018-0654-0.


Efficacy of tiotropium/olodaterol on lung volume, exercise capacity, and physical activity.

Ichinose M, Minakata Y, Motegi T, Ueki J, Gon Y, Seki T, Anzai T, Nakamura S, Hirata K.

Int J Chron Obstruct Pulmon Dis. 2018 May 1;13:1407-1419. doi: 10.2147/COPD.S166023. eCollection 2018.


Physical inactivity is associated with decreased growth differentiation factor 11 in chronic obstructive pulmonary disease.

Tanaka R, Sugiura H, Yamada M, Ichikawa T, Koarai A, Fujino N, Yanagisawa S, Onodera K, Numakura T, Sato K, Kyogoku Y, Sano H, Yamanaka S, Okazaki T, Tamada T, Miura M, Takahashi T, Ichinose M.

Int J Chron Obstruct Pulmon Dis. 2018 Apr 24;13:1333-1342. doi: 10.2147/COPD.S157035. eCollection 2018.


The DYW Domains of Pentatricopeptide Repeat RNA Editing Factors Contribute to Discriminate Target and Non-Target Editing Sites.

Ichinose M, Sugita M.

Plant Cell Physiol. 2018 Aug 1;59(8):1652-1659. doi: 10.1093/pcp/pcy086.


Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis.

Lannagan TRM, Lee YK, Wang T, Roper J, Bettington ML, Fennell L, Vrbanac L, Jonavicius L, Somashekar R, Gieniec K, Yang M, Ng JQ, Suzuki N, Ichinose M, Wright JA, Kobayashi H, Putoczki TL, Hayakawa Y, Leedham SJ, Abud HE, Yilmaz ÖH, Marker J, Klebe S, Wirapati P, Mukherjee S, Tejpar S, Leggett BA, Whitehall VLJ, Worthley DL, Woods SL.

Gut. 2019 Apr;68(4):684-692. doi: 10.1136/gutjnl-2017-315920. Epub 2018 Apr 17.


Sympathoexcitation constrains vasodilation in the human skeletal muscle microvasculature during postocclusive reactive hyperemia.

Ichinose M, Nakabayashi M, Ono Y.

Am J Physiol Heart Circ Physiol. 2018 Aug 1;315(2):H242-H253. doi: 10.1152/ajpheart.00010.2018. Epub 2018 Apr 13.


Atomoxetine, a selective norepinephrine reuptake inhibitor, improves short-term histological outcomes after hypoxic-ischemic brain injury in the neonatal male rat.

Toshimitsu M, Kamei Y, Ichinose M, Seyama T, Imada S, Iriyama T, Fujii T.

Int J Dev Neurosci. 2018 Nov;70:34-45. doi: 10.1016/j.ijdevneu.2018.03.011. Epub 2018 Mar 30.


Possible involvement of acetylcholine-mediated inflammation in airway diseases.

Koarai A, Ichinose M.

Allergol Int. 2018 Oct;67(4):460-466. doi: 10.1016/j.alit.2018.02.008. Epub 2018 Mar 28. Review.


Oxidative stress enhances the expression of IL-33 in human airway epithelial cells.

Aizawa H, Koarai A, Shishikura Y, Yanagisawa S, Yamaya M, Sugiura H, Numakura T, Yamada M, Ichikawa T, Fujino N, Noda M, Okada Y, Ichinose M.

Respir Res. 2018 Mar 27;19(1):52. doi: 10.1186/s12931-018-0752-9. Erratum in: Respir Res. 2018 Jun 12;19(1):116.


Peripheral alveolar nitric oxide concentration reflects alveolar inflammation in autoimmune pulmonary alveolar proteinosis.

Hirano T, Ohkouchi S, Tode N, Kobayashi M, Ono M, Satoh T, Mitsuishi Y, Watanabe A, Tabata M, Irokawa T, Ogawa H, Sugiura H, Kikuchi T, Akasaka K, Tazawa R, Inoue Y, Nakata K, Kurosawa H, Ichinose M.

ERJ Open Res. 2018 Mar 23;4(1). pii: 00071-2017. doi: 10.1183/23120541.00071-2017. eCollection 2018 Jan.


An evolutionarily conserved P-subfamily pentatricopeptide repeat protein is required to splice the plastid ndhA transcript in the moss Physcomitrella patens and Arabidopsis thaliana.

Ito A, Sugita C, Ichinose M, Kato Y, Yamamoto H, Shikanai T, Sugita M.

Plant J. 2018 May;94(4):638-648. doi: 10.1111/tpj.13884. Epub 2018 Apr 1.

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