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Items: 49

1.

Effect of meropenem on disposition kinetics of valproate and its metabolites in rabbits.

Yokogawa K, Iwashita S, Kubota A, Sasaki Y, Ishizaki J, Kawahara M, Matsushita R, Kimura K, Ichimura F, Miyamoto K.

Pharm Res. 2001 Sep;18(9):1320-6.

PMID:
11683247
2.

Kinetic phenotypic diagnosis of N-acetylation polymorphism in patients based on ratio of urinary metabolites of salicylazosulfapyridine.

Yokogawa K, Nakaharu T, Ishizaki J, Ozaki E, Takeda Y, Mabuchi H, Matsushita R, Kimura K, Nakashima E, Ichimura F, Miyamoto K.

Int J Pharm. 2001 Oct 23;229(1-2):183-91.

PMID:
11604271
3.

[Studies on the mechanism of subcellular distribution of basic drugs based on their lipophilicity].

Ishizaki J, Yokogawa K, Ohkuma S, Ichimura F, Miyamoto K.

Yakugaku Zasshi. 2001 Jul;121(7):557-65. Review. Japanese.

4.

Synergistic effect of indomethacin and bleomycin on tumor growth produced by activating antitumor immunity.

Matsushita R, Hattori K, Hayashi K, Iizasa H, Ichimura F, Nakashima E.

Pharm Res. 2001 Feb;18(2):243-5. No abstract available.

PMID:
11405298
5.

Uptake of imipramine in rat liver lysosomes in vitro and its inhibition by basic drugs.

Ishizaki J, Yokogawa K, Ichimura F, Ohkuma S.

J Pharmacol Exp Ther. 2000 Sep;294(3):1088-98.

PMID:
10945864
6.

Uptake of basic drugs into rat lung granule fraction in vitro.

Ishizaki J, Yokogawa K, Nakashima E, Ohkuma S, Ichimura F.

Biol Pharm Bull. 1998 Aug;21(8):858-61.

PMID:
9743257
7.

Influence of ammonium chloride on the tissue distribution of anticholinergic drugs in rats.

Ishizaki J, Yokogawa K, Nakashima E, Ohkuma S, Ichimura F.

J Pharm Pharmacol. 1998 Jul;50(7):761-6.

PMID:
9720625
8.

Synergistic antitumor interaction of human monocyte chemotactant protein-1 gene transfer and modulator for tumor-infiltrating macrophages.

Nakashima E, Kubota Y, Matsushita R, Ozaki E, Ichimura F, Kawahara S, Nakanishi I, Kuno K, Matsushima K.

Pharm Res. 1998 May;15(5):685-9.

PMID:
9619775
9.
10.

Characteristic subcellular distribution, in brain, heart and lung, of biperiden, trihexyphenidyl, and (-)-quinuclidinyl benzylate in rats.

Ishizaki J, Yokogawa K, Nakashima E, Ohkuma S, Ichimura F.

Biol Pharm Bull. 1998 Jan;21(1):67-71.

PMID:
9477171
11.
12.

Prediction of changes in the clinical pharmacokinetics of basic drugs on the basis of octanol-water partition coefficients.

Ishizaki J, Yokogawa K, Nakashima E, Ichimura F.

J Pharm Pharmacol. 1997 Aug;49(8):762-7.

PMID:
9379352
13.
14.

A candidate for cancer gene therapy: MIP-1 alpha gene transfer to an adenocarcinoma cell line reduced tumorigenicity and induced protective immunity in immunocompetent mice.

Nakashima E, Oya A, Kubota Y, Kanada N, Matsushita R, Takeda K, Ichimura F, Kuno K, Mukaida N, Hirose K, Nakanishi I, Ujiie T, Matsushima K.

Pharm Res. 1996 Dec;13(12):1896-901.

PMID:
8987092
15.

Contribution of lysosomes to the subcellular distribution of basic drugs in the rat liver.

Ishizaki J, Yokogawa K, Hirano M, Nakashima E, Sai Y, Ohkuma S, Ohshima T, Ichimura F.

Pharm Res. 1996 Jun;13(6):902-6.

PMID:
8792430
16.

Kinetic evidence for facilitated peritoneal transport of benzoic acid in rats.

Nakashima E, Matsushita R, Kanada N, Ichimura F.

J Pharm Pharmacol. 1996 Apr;48(4):347-50.

PMID:
8794981
17.

Human MCAF gene transfer enhances the metastatic capacity of a mouse cachectic adenocarcinoma cell line in vivo.

Nakashima E, Mukaida N, Kubota Y, Kuno K, Yasumoto K, Ichimura F, Nakanishi I, Miyasaka M, Matsushima K.

Pharm Res. 1995 Nov;12(11):1598-604.

PMID:
8592656
18.

Quantitative relationship between structure and peritoneal membrane transport based on physiological pharmacokinetic concepts for acidic drugs.

Nakashima E, Matsushita R, Ohshima T, Tsuji A, Ichimura F.

Drug Metab Dispos. 1995 Nov;23(11):1220-4.

PMID:
8591722
19.

Reversal of drug sensitivity in MDR subline of P388 leukemia by gene-targeted antisense oligonucleotide.

Nakashima E, Matsushita R, Negishi H, Nomura M, Harada S, Yamamoto H, Miyamoto K, Ichimura F.

J Pharm Sci. 1995 Oct;84(10):1205-9.

PMID:
8801335
20.

Age-related changes in pharmacokinetic parameters of phenytoin after liver resection in rats.

Nakashima E, Matsushita R, Iida Y, Ohshima T, Ichimura F.

Pharm Res. 1995 Oct;12(10):1530-4. No abstract available.

PMID:
8584494
21.

Systematic approach to a dosage regimen for phenytoin based on one-point, steady-state plasma concentration.

Nakashima E, Matsushita R, Kido H, Nakamura M, Asahi M, Ichimura F.

Ther Drug Monit. 1995 Feb;17(1):12-8.

PMID:
7725371
22.

Pharmacokinetics of anticholinergic drugs and brain muscarinic receptor alterations in streptozotocin diabetic rats.

Nakashima E, Ishizaki J, Takeda M, Matsushita R, Yokogawa K, Ichimura F.

Biopharm Drug Dispos. 1993 Nov;14(8):673-84.

PMID:
8305628
23.

Time course of dopamine-D2 and serotonin-5-HT2 receptor occupancy rates by haloperidol and clozapine in vivo.

Sumiyoshi T, Kido H, Sakamoto H, Urasaki K, Suzuki K, Yamaguchi N, Mori H, Shiba K, Yokogawa K, Ichimura F.

Jpn J Psychiatry Neurol. 1993 Mar;47(1):131-7.

PMID:
8411785
24.

Comparative pharmacokinetics of cefoperazone and cephradine in untreated streptozotocin diabetic rats.

Nakashima E, Matsushita R, Takeda M, Nakanishi T, Ichimura F.

Drug Metab Dispos. 1992 Sep-Oct;20(5):730-5.

PMID:
1358579
25.

A physiologically based pharmacokinetic model for (-)-quinuclidinyl benzylate using nonlinear irreversible tissue binding parameters in rats.

Ishizaki J, Nakashima E, Yokogawa K, Nagano T, Takayasu T, Ichimura F.

Drug Metab Dispos. 1992 Jul-Aug;20(4):485-9.

PMID:
1356722
26.

Brain regional pharmacokinetics of biperiden in rats.

Yokogawa K, Nakashima E, Ishizaki J, Hasegawa M, Kido H, Ichimura F.

Biopharm Drug Dispos. 1992 Mar;13(2):131-40.

PMID:
1550908
27.

Mutual interaction between bilirubin and cefazolin in binding to human serum albumin.

Ichimura F, Matsushita R, Tsuji A, Deguchi Y.

J Pharm Sci. 1990 Nov;79(11):1041-2. No abstract available.

PMID:
2292768
28.

Relationships in the structure-tissue distribution of basic drugs in the rabbit.

Yokogawa K, Nakashima E, Ishizaki J, Maeda H, Nagano T, Ichimura F.

Pharm Res. 1990 Jul;7(7):691-6.

PMID:
2395795
29.

Effect of fat tissue volume on the distribution kinetics of biperiden as a function of age in rats.

Yokogawa K, Nakashima E, Ichimura F.

Drug Metab Dispos. 1990 Mar-Apr;18(2):258-63.

PMID:
1971583
30.

Prediction of the distribution volumes of cefazolin and tobramycin in obese children based on physiological pharmacokinetic concepts.

Koshida R, Nakashima E, Taniguchi N, Tsuji A, Benet LZ, Ichimura F.

Pharm Res. 1989 Jun;6(6):486-91.

PMID:
2762224
31.

Interindividual changes in volume of distribution of cefazolin in newborn infants and its prediction based on physiological pharmacokinetic concepts.

Deguchi Y, Koshida R, Nakashima E, Watanabe R, Taniguchi N, Ichimura F, Tsuji A.

J Pharm Sci. 1988 Aug;77(8):674-8.

PMID:
3210156
32.

Kinetic analysis of the peritoneal transport of quinolonecarboxylic acids in rats.

Sato H, Ishikawa F, Okezaki E, Nagata O, Nakashima E, Deguchi Y, Ichimura F, Tsuji A.

Chem Pharm Bull (Tokyo). 1988 Aug;36(8):3180-5. No abstract available.

PMID:
2853652
33.

Peritoneal transport of beta-lactam antibiotics: effects of plasma protein binding and the interspecies relationship.

Deguchi Y, Nakashima E, Ishikawa F, Sato H, Tamai I, Matsushita R, Tofuku Y, Ichimura F, Tsuji A.

J Pharm Sci. 1988 Jul;77(7):559-64.

PMID:
3171941
34.

Kinetics of peritoneal drug transport in rats: an application of the pore theory of transcapillary exchange.

Nakashima E, Ishikawa F, Sato H, Deguchi Y, Tamai I, Matsushita R, Ichimura F, Tsuji A.

J Pharm Sci. 1988 Jun;77(6):481-8.

PMID:
3171925
35.

Comparative distribution kinetics of cefazolin and tobramycin in children.

Koshida R, Nakashima E, Ichimura F, Nakano O, Watanabe R, Taniguchi N, Tsuji A.

J Pharmacobiodyn. 1987 Sep;10(9):436-42.

PMID:
3437384
36.

The effects of valproate on plasma concentration of phenytoin in normal and D-galactosamine-treated rats.

Ichimura F, Deguchi Y, Yokogawa K, Nakashima E.

Chem Pharm Bull (Tokyo). 1987 May;35(5):2030-7. No abstract available.

PMID:
3117387
37.

A physiologically based pharmacokinetic model for biperiden in animals and its extrapolation to humans.

Nakashima E, Yokogawa K, Ichimura F, Kurata K, Kido H, Yamaguchi N, Yamana T.

Chem Pharm Bull (Tokyo). 1987 Feb;35(2):718-25. No abstract available.

PMID:
3594682
38.

Effects of fasting on biperiden pharmacokinetics in the rat.

Nakashima E, Yokogawa K, Ichimura F, Hashimoto T, Yamana T, Tsuji A.

J Pharm Sci. 1987 Jan;76(1):10-3.

PMID:
3585715
39.

Fundamental pharmacokinetic properties of biperiden: tissue distribution and elimination in rabbits.

Yokogawa K, Nakashima E, Ichimura F, Yamana T.

J Pharmacobiodyn. 1986 Apr;9(4):409-16.

PMID:
3735062
40.
41.

[Effects of regional nursing activities directed to patients with myocardial infarct on their social rehabilitation].

Miyake A, Ichimura F, Takizawa H.

Kango Gijutsu. 1979 Apr;25(5):117-25. Japanese. No abstract available.

PMID:
255164
42.

[Studies on the hydrolysis of ethyl glucuronate in phosphate buffer solutions].

Yamana T, Mizukami Y, Ichimura F.

Yakugaku Zasshi. 1969 Oct;89(10):1338-44. Japanese. No abstract available.

PMID:
5389576
43.

[Studies on the stability of drugs. XX. Stability of benzothiadiazines. Studies on the hydrolysis of hydrochlorothiazide in the various pH solutions].

Yamana T, Mizukami Y, Tsuji A, Ichimura F.

Yakugaku Zasshi. 1969 May;89(5):740-4. Japanese. No abstract available.

PMID:
5818015
44.

[Studies on the hydrolysis of glucuronamide in phosphate buffer solutions].

Yamana T, Mizukami Y, Ichimura F.

Yakugaku Zasshi. 1969 Feb;89(2):173-81. Japanese. No abstract available.

PMID:
5815510
45.

[Studies on the hydrolysis of glucuronolactone in phosphate buffer solutions].

Yamana T, Mizukami Y, Ichimura F.

Yakugaku Zasshi. 1968 Dec;88(12):1504-11. Japanese. No abstract available.

PMID:
5752577
46.

On the acid hydrolysis mechanism of ethyl D-glucuronate.

Yamana T, Mizukami Y, Ichimura F.

Chem Pharm Bull (Tokyo). 1966 May;14(5):479-81. No abstract available.

PMID:
5939660
47.

[Studies on the stability of drugs. 13. Stability of benzothiadiazine. (5). Degradation mechanism of chlorothiazide in alkaline solution. (supplement)].

Yamana T, Mizukami Y, Ichimura F.

Yakugaku Zasshi. 1965 Jul;85(7):654-5. Japanese. No abstract available.

PMID:
5890316
48.

[STUDIES ON THE STABILITY OF DRUGS. XII. STABILITY OF BENZOTHIADIAZINES. (4). A SIMPLIFIED METHOD FOR THE CALCULATION OF RATE CONSTANTS OF COMPLICATED REACTIONS].

YAMANA T, MIZUKAMI Y, ICHIMURA F, KOIKE H.

Yakugaku Zasshi. 1964 Oct;84:974-6. Japanese. No abstract available.

PMID:
14250874
49.

[ON THE DEGRADATION MECHANISM OF CHLOROTHIAZIDE IN ALKALINE SOLUTION].

YAMANA T, MIZUKAMI Y, ICHIMURA F, KOIKE H, MOTOYA T.

Yakugaku Zasshi. 1964 Jun;84:570. Japanese. No abstract available.

PMID:
14207119

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