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Items: 1 to 50 of 326

1.

Iron homeostasis and iron-regulated ROS in cell death, senescence and human diseases.

Nakamura T, Naguro I, Ichijo H.

Biochim Biophys Acta Gen Subj. 2019 Sep;1863(9):1398-1409. doi: 10.1016/j.bbagen.2019.06.010. Epub 2019 Jun 20. Review.

PMID:
31229492
2.

Cell volume regulation in cancer cell migration driven by osmotic water flow.

Morishita K, Watanabe K, Ichijo H.

Cancer Sci. 2019 Aug;110(8):2337-2347. doi: 10.1111/cas.14079. Epub 2019 Jul 1. Review.

3.

A new treatment (the affected-ear-up 90° maneuver) for benign paroxysmal positional vertigo of the lateral semicircular canal.

Ichijo H.

Acta Otolaryngol. 2019 Jul;139(7):588-592. doi: 10.1080/00016489.2019.1609700. Epub 2019 May 8.

PMID:
31066612
4.

[Functional Analysis of Apoptosis Signal-regulating Kinase Family in a Murine Model of Tumor Metastasis].

Kamiyama M, Naguro I, Ichijo H.

Yakugaku Zasshi. 2019;139(5):743-751. doi: 10.1248/yakushi.18-00185-2. Review. Japanese.

5.

Atlas of the telencephalon based on cytoarchitecture, neurochemical markers, and gene expressions in Rhinogobius flumineus [Mizuno, 1960].

Kawaguchi M, Hagio H, Yamamoto N, Matsumoto K, Nakayama K, Akazome Y, Izumi H, Tsuneoka Y, Suto F, Murakami Y, Ichijo H.

J Comp Neurol. 2019 Mar 1;527(4):874-900. doi: 10.1002/cne.24547. Epub 2018 Dec 5.

PMID:
30516281
6.

Cryo-EM structures of the human volume-regulated anion channel LRRC8.

Kasuya G, Nakane T, Yokoyama T, Jia Y, Inoue M, Watanabe K, Nakamura R, Nishizawa T, Kusakizako T, Tsutsumi A, Yanagisawa H, Dohmae N, Hattori M, Ichijo H, Yan Z, Kikkawa M, Shirouzu M, Ishitani R, Nureki O.

Nat Struct Mol Biol. 2018 Sep;25(9):797-804. doi: 10.1038/s41594-018-0109-6. Epub 2018 Aug 20.

PMID:
30127360
7.

β-TrCP-dependent degradation of ASK1 suppresses the induction of the apoptotic response by oxidative stress.

Cheng R, Takeda K, Naguro I, Hatta T, Iemura SI, Natsume T, Ichijo H, Hattori K.

Biochim Biophys Acta Gen Subj. 2018 Oct;1862(10):2271-2280. doi: 10.1016/j.bbagen.2018.07.015. Epub 2018 Jul 18.

PMID:
30031111
8.

A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model.

Tsuburaya N, Homma K, Higuchi T, Balia A, Yamakoshi H, Shibata N, Nakamura S, Nakagawa H, Ikeda SI, Umezawa N, Kato N, Yokoshima S, Shibuya M, Shimonishi M, Kojima H, Okabe T, Nagano T, Naguro I, Imamura K, Inoue H, Fujisawa T, Ichijo H.

Nat Commun. 2018 Jul 10;9(1):2668. doi: 10.1038/s41467-018-05127-2.

9.

ASK family kinases mediate cellular stress and redox signaling to circadian clock.

Imamura K, Yoshitane H, Hattori K, Yamaguchi M, Yoshida K, Okubo T, Naguro I, Ichijo H, Fukada Y.

Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3646-3651. doi: 10.1073/pnas.1719298115. Epub 2018 Mar 19.

10.

A PP6-ASK3 Module Coordinates the Bidirectional Cell Volume Regulation under Osmotic Stress.

Watanabe K, Umeda T, Niwa K, Naguro I, Ichijo H.

Cell Rep. 2018 Mar 13;22(11):2809-2817. doi: 10.1016/j.celrep.2018.02.045.

11.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review.

12.

TRIM48 Promotes ASK1 Activation and Cell Death through Ubiquitination-Dependent Degradation of the ASK1-Negative Regulator PRMT1.

Hirata Y, Katagiri K, Nagaoka K, Morishita T, Kudoh Y, Hatta T, Naguro I, Kano K, Udagawa T, Natsume T, Aoki J, Inada T, Noguchi T, Ichijo H, Matsuzawa A.

Cell Rep. 2017 Nov 28;21(9):2447-2457. doi: 10.1016/j.celrep.2017.11.007.

13.

Apoptosis signal-regulating kinase 1 in regulated necrosis.

Hattori K, Ichijo H.

Cell Cycle. 2018;17(1):5-6. doi: 10.1080/15384101.2017.1397330. Epub 2018 Jan 2. No abstract available.

14.

mASKing cancer cells in a tumor microenvironment.

Kamiyama M, Naguro I, Ichijo H.

Cell Cycle. 2018;17(2):139-140. doi: 10.1080/15384101.2017.1407402. Epub 2018 Jan 4. No abstract available.

15.

Role of ASK1/p38 Cascade in a Mouse Model of Alzheimer's Disease and Brain Aging.

Hasegawa Y, Toyama K, Uekawa K, Ichijo H, Kim-Mitsuyama S.

J Alzheimers Dis. 2018;61(1):259-263. doi: 10.3233/JAD-170645.

PMID:
29154282
16.

Foreword.

Ichijo H.

Adv Biol Regul. 2017 Dec;66:1. doi: 10.1016/j.jbior.2017.11.002. Epub 2017 Nov 11. No abstract available.

PMID:
29137882
17.

Caloric testing in patients with heavy or light cupula of the lateral semicircular canal.

Ichijo H.

Laryngoscope Investig Otolaryngol. 2016 Nov 22;1(6):163-168. doi: 10.1002/lio2.39. eCollection 2016 Dec.

18.

Cold stress-induced ferroptosis involves the ASK1-p38 pathway.

Hattori K, Ishikawa H, Sakauchi C, Takayanagi S, Naguro I, Ichijo H.

EMBO Rep. 2017 Nov;18(11):2067-2078. doi: 10.15252/embr.201744228. Epub 2017 Sep 8.

19.

Gender difference and laterality of sleep position.

Ichijo H, Akita M.

Auris Nasus Larynx. 2018 Jun;45(3):592-597. doi: 10.1016/j.anl.2017.08.004. Epub 2017 Aug 31.

PMID:
28863980
20.

ASK1 facilitates tumor metastasis through phosphorylation of an ADP receptor P2Y12 in platelets.

Kamiyama M, Shirai T, Tamura S, Suzuki-Inoue K, Ehata S, Takahashi K, Miyazono K, Hayakawa Y, Sato T, Takeda K, Naguro I, Ichijo H.

Cell Death Differ. 2017 Dec;24(12):2066-2076. doi: 10.1038/cdd.2017.114. Epub 2017 Jul 28.

21.

Affected-ear-up 120° maneuver for treatment of lateral semicircular canal benign paroxysmal positional vertigo.

Ichijo H.

Eur Arch Otorhinolaryngol. 2017 Sep;274(9):3351-3357. doi: 10.1007/s00405-017-4663-z. Epub 2017 Jul 6.

PMID:
28685312
22.

Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly.

Chaikuad A, Filippakopoulos P, Marcsisin SR, Picaud S, Schröder M, Sekine S, Ichijo H, Engen JR, Takeda K, Knapp S.

Structure. 2017 Jul 5;25(7):1089-1099.e3. doi: 10.1016/j.str.2017.05.020. Epub 2017 Jun 22.

23.

Involvement of apoptosis signal-regulating kinase-1 in house dust mite-induced allergic asthma in mice.

Maruoka S, Gon Y, Mizumura K, Okamoto S, Tsuya K, Shikano S, Soda K, Naguro I, Ichijo H, Hashimoto S.

Allergol Int. 2017 Sep;66S:S50-S52. doi: 10.1016/j.alit.2017.05.007. Epub 2017 Jun 16. No abstract available.

24.

The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.

Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, Kunath T, Wray S, Furuya H, Era T, Makioka K, Okamoto K, Fujisawa T, Nishitoh H, Homma K, Ichijo H, Julien JP, Obata N, Hosokawa M, Akiyama H, Kaneko S, Ayaki T, Ito H, Kaji R, Takahashi R, Yamanaka S, Inoue H.

Sci Transl Med. 2017 May 24;9(391). pii: eaaf3962. doi: 10.1126/scitranslmed.aaf3962.

25.

An Evolutionary Hypothesis of Binary Opposition in Functional Incompatibility about Habenular Asymmetry in Vertebrates.

Ichijo H, Nakamura T, Kawaguchi M, Takeuchi Y.

Front Neurosci. 2017 Jan 4;10:595. doi: 10.3389/fnins.2016.00595. eCollection 2016.

26.

Ask1 regulates murine platelet granule secretion, thromboxane A2 generation, and thrombus formation.

Naik MU, Patel P, Derstine R, Turaga R, Chen X, Golla K, Neeves KB, Ichijo H, Naik UP.

Blood. 2017 Mar 2;129(9):1197-1209. doi: 10.1182/blood-2016-07-729780. Epub 2016 Dec 27.

27.

Pleiotropic properties of ASK1.

Sakauchi C, Wakatsuki H, Ichijo H, Hattori K.

Biochim Biophys Acta Gen Subj. 2017 Jan;1861(1 Pt A):3030-3038. doi: 10.1016/j.bbagen.2016.09.028. Epub 2016 Sep 30. Review.

PMID:
27693599
28.

KLHDC10 Deficiency Protects Mice against TNFα-Induced Systemic Inflammation.

Yamaguchi N, Sekine S, Naguro I, Sekine Y, Ichijo H.

PLoS One. 2016 Sep 15;11(9):e0163118. doi: 10.1371/journal.pone.0163118. eCollection 2016.

29.

Onset time of benign paroxysmal positional vertigo.

Ichijo H.

Acta Otolaryngol. 2017 Feb;137(2):144-148. doi: 10.1080/00016489.2016.1221130. Epub 2016 Aug 31.

PMID:
27577049
30.

The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction.

Koizumi S, Irie T, Hirayama S, Sakurai Y, Yashiroda H, Naguro I, Ichijo H, Hamazaki J, Murata S.

Elife. 2016 Aug 16;5. pii: e18357. doi: 10.7554/eLife.18357.

31.

[Zinc depletion and ER stress].

Homma K, Ichijo H.

Nihon Rinsho. 2016 Jul;74(7):1228-33. Japanese.

PMID:
27455816
32.

Mitogen-activated protein kinases as key players in osmotic stress signaling.

Zhou X, Naguro I, Ichijo H, Watanabe K.

Biochim Biophys Acta. 2016 Sep;1860(9):2037-52. doi: 10.1016/j.bbagen.2016.05.032. Epub 2016 May 31. Review.

PMID:
27261090
33.

PO-16 - ASK1 regulates tumor lung metastasis and platelet functions.

Kamiyama M, Naguro I, Ichijo H.

Thromb Res. 2016 Apr;140 Suppl 1:S182. doi: 10.1016/S0049-3848(16)30149-9. Epub 2016 Apr 8.

PMID:
27161706
34.

The Ablation of Mitochondrial Protein Phosphatase Pgam5 Confers Resistance Against Metabolic Stress.

Sekine S, Yao A, Hattori K, Sugawara S, Naguro I, Koike M, Uchiyama Y, Takeda K, Ichijo H.

EBioMedicine. 2016 Jan 29;5:82-92. doi: 10.1016/j.ebiom.2016.01.031. eCollection 2016 Mar.

35.

ASK1 signalling regulates brown and beige adipocyte function.

Hattori K, Naguro I, Okabe K, Funatsu T, Furutani S, Takeda K, Ichijo H.

Nat Commun. 2016 Apr 5;7:11158. doi: 10.1038/ncomms11158.

36.

Docosahexaenoic Acid Promotes Axon Outgrowth by Translational Regulation of Tau and Collapsin Response Mediator Protein 2 Expression.

Mita T, Mayanagi T, Ichijo H, Fukumoto K, Otsuka K, Sakai A, Sobue K.

J Biol Chem. 2016 Mar 4;291(10):4955-65. doi: 10.1074/jbc.M115.693499. Epub 2016 Jan 13.

37.

Osmotic stress induces the phosphorylation of WNK4 Ser575 via the p38MAPK-MK pathway.

Maruyama J, Kobayashi Y, Umeda T, Vandewalle A, Takeda K, Ichijo H, Naguro I.

Sci Rep. 2016 Jan 6;6:18710. doi: 10.1038/srep18710.

38.

The ASK1-specific inhibitors K811 and K812 prolong survival in a mouse model of amyotrophic lateral sclerosis.

Fujisawa T, Takahashi M, Tsukamoto Y, Yamaguchi N, Nakoji M, Endo M, Kodaira H, Hayashi Y, Nishitoh H, Naguro I, Homma K, Ichijo H.

Hum Mol Genet. 2016 Jan 15;25(2):245-53. doi: 10.1093/hmg/ddv467. Epub 2015 Nov 24.

PMID:
26604152
39.

Pre-emptive Quality Control Protects the ER from Protein Overload via the Proximity of ERAD Components and SRP.

Kadowaki H, Nagai A, Maruyama T, Takami Y, Satrimafitrah P, Kato H, Honda A, Hatta T, Natsume T, Sato T, Kai H, Ichijo H, Nishitoh H.

Cell Rep. 2015 Nov 3;13(5):944-56. doi: 10.1016/j.celrep.2015.09.047. Epub 2015 Oct 22.

40.

SOD1 in neurotoxicity and its controversial roles in SOD1 mutation-negative ALS.

Hayashi Y, Homma K, Ichijo H.

Adv Biol Regul. 2016 Jan;60:95-104. doi: 10.1016/j.jbior.2015.10.006. Epub 2015 Oct 31. Review.

PMID:
26563614
41.

Erratum: ASK1 is involved in cognitive impairment caused by long-term high-fat diet feeding in mice.

Toyama K, Koibuchi N, Hasegawa Y, Uekawa K, Yasuda O, Sueta D, Nakagawa T, Ma M, Kusaka H, Lin B, Ogawa H, Ichijo H, Kim-Mitsuyama S.

Sci Rep. 2015 Oct 8;5:14028. doi: 10.1038/srep14028. No abstract available.

42.

A systematic immunoprecipitation approach reinforces the concept of common conformational alterations in amyotrophic lateral sclerosis-linked SOD1 mutants.

Fujisawa T, Yamaguchi N, Kadowaki H, Tsukamoto Y, Tsuburaya N, Tsubota A, Takahashi H, Naguro I, Takahashi Y, Goto J, Tsuji S, Nishitoh H, Homma K, Ichijo H.

Neurobiol Dis. 2015 Oct;82:478-486. doi: 10.1016/j.nbd.2015.08.010. Epub 2015 Aug 18.

PMID:
26297318
43.

The ASK family kinases differentially mediate induction of type I interferon and apoptosis during the antiviral response.

Okazaki T, Higuchi M, Takeda K, Iwatsuki-Horimoto K, Kiso M, Miyagishi M, Yanai H, Kato A, Yoneyama M, Fujita T, Taniguchi T, Kawaoka Y, Ichijo H, Gotoh Y.

Sci Signal. 2015 Aug 4;8(388):ra78. doi: 10.1126/scisignal.aab1883. Erratum in: Sci Signal. 2017 May 30;10 (481):.

PMID:
26243192
44.

Inhibition of Cytohesins Protects against Genetic Models of Motor Neuron Disease.

Zhai J, Zhang L, Mojsilovic-Petrovic J, Jian X, Thomas J, Homma K, Schmitz A, Famulok M, Ichijo H, Argon Y, Randazzo PA, Kalb RG.

J Neurosci. 2015 Jun 17;35(24):9088-105. doi: 10.1523/JNEUROSCI.5032-13.2015.

45.

ASK1 is involved in cognitive impairment caused by long-term high-fat diet feeding in mice.

Toyama K, Koibuchi N, Hasegawa Y, Uekawa K, Yasuda O, Sueta D, Nakagawa T, Ma M, Kusaka H, Lin B, Ogawa H, Ichijo H, Kim-Mitsuyama S.

Sci Rep. 2015 Jun 5;5:10844. doi: 10.1038/srep10844. Erratum in: Sci Rep. 2015;5:14028. Ichijo, Hidenor [corrected to Ichijo, Hidenori].

46.

ASK1 restores the antiviral activity of APOBEC3G by disrupting HIV-1 Vif-mediated counteraction.

Miyakawa K, Matsunaga S, Kanou K, Matsuzawa A, Morishita R, Kudoh A, Shindo K, Yokoyama M, Sato H, Kimura H, Tamura T, Yamamoto N, Ichijo H, Takaori-Kondo A, Ryo A.

Nat Commun. 2015 Apr 22;6:6945. doi: 10.1038/ncomms7945.

47.

In vivo gene manipulation reveals the impact of stress-responsive MAPK pathways on tumor progression.

Kamiyama M, Naguro I, Ichijo H.

Cancer Sci. 2015 Jul;106(7):785-96. doi: 10.1111/cas.12676. Epub 2015 May 25. Review.

48.

Apoptosis Signal-regulating Kinase 1 (ASK1)-p38 Pathway-dependent Cytoplasmic Translocation of the Orphan Nuclear Receptor NR4A2 Is Required for Oxidative Stress-induced Necrosis.

Watanabe T, Sekine S, Naguro I, Sekine Y, Ichijo H.

J Biol Chem. 2015 Apr 24;290(17):10791-803. doi: 10.1074/jbc.M114.623280. Epub 2015 Mar 9.

49.

Lateralization, maturation, and anteroposterior topography in the lateral habenula revealed by ZIF268/EGR1 immunoreactivity and labeling history of neuronal activity.

Ichijo H, Hamada M, Takahashi S, Kobayashi M, Nagai T, Toyama T, Kawaguchi M.

Neurosci Res. 2015 Jun;95:27-37. doi: 10.1016/j.neures.2015.01.005. Epub 2015 Jan 27.

PMID:
25637311
50.

Neutral position of persistent direction-changing positional nystagmus.

Ichijo H.

Eur Arch Otorhinolaryngol. 2016 Feb;273(2):311-6. doi: 10.1007/s00405-014-3487-3. Epub 2015 Jan 23.

PMID:
25613295

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