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Items: 39


Aspergillus fumigatus conidial metalloprotease Mep1p cleaves host complement proteins.

Shende R, Wong SSW, Rapole S, Beau R, Ibrahim-Granet O, Monod M, Gührs KH, Pal JK, Latgé JP, Madan T, Aimanianda V, Sahu A.

J Biol Chem. 2018 Oct 5;293(40):15538-15555. doi: 10.1074/jbc.RA117.001476. Epub 2018 Aug 23.


Genetic deficiency of NOD2 confers resistance to invasive aspergillosis.

Gresnigt MS, Cunha C, Jaeger M, Gonçalves SM, Malireddi RKS, Ammerdorffer A, Lubbers R, Oosting M, Rasid O, Jouvion G, Fitting C, Jong DJ, Lacerda JF, Campos A Jr, Melchers WJG, Lagrou K, Maertens J, Kanneganti TD, Carvalho A, Ibrahim-Granet O, van de Veerdonk FL.

Nat Commun. 2018 Jul 6;9(1):2636. doi: 10.1038/s41467-018-04912-3.


A Novel Polyaminocarboxylate Compound To Treat Murine Pulmonary Aspergillosis by Interfering with Zinc Metabolism.

Laskaris P, Vicentefranqueira R, Helynck O, Jouvion G, Calera JA, du Merle L, Suzenet F, Buron F, de Sousa RA, Mansuy D, Cavaillon JM, Latgé JP, Munier-Lehmann H, Ibrahim-Granet O.

Antimicrob Agents Chemother. 2018 May 25;62(6). pii: e02510-17. doi: 10.1128/AAC.02510-17. Print 2018 Jun.


Fungal melanin stimulates surfactant protein D-mediated opsonization of and host immune response to Aspergillus fumigatus spores.

Wong SSW, Rani M, Dodagatta-Marri E, Ibrahim-Granet O, Kishore U, Bayry J, Latgé JP, Sahu A, Madan T, Aimanianda V.

J Biol Chem. 2018 Mar 30;293(13):4901-4912. doi: 10.1074/jbc.M117.815852. Epub 2018 Feb 5.


The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression.

Gresnigt MS, Jaeger M, Subbarao Malireddi RK, Rasid O, Jouvion G, Fitting C, Melchers WJG, Kanneganti TD, Carvalho A, Ibrahim-Granet O, van de Veerdonk FL.

Front Immunol. 2017 Dec 13;8:1777. doi: 10.3389/fimmu.2017.01777. eCollection 2017.


MybA, a transcription factor involved in conidiation and conidial viability of the human pathogen Aspergillus fumigatus.

Valsecchi I, Sarikaya-Bayram Ö, Wong Sak Hoi J, Muszkieta L, Gibbons J, Prevost MC, Mallet A, Krijnse-Locker J, Ibrahim-Granet O, Mouyna I, Carr P, Bromley M, Aimanianda V, Yu JH, Rokas A, Braus GH, Saveanu C, Bayram Ö, Latgé JP.

Mol Microbiol. 2017 Sep;105(6):880-900. doi: 10.1111/mmi.13744. Epub 2017 Jul 21.


Treatment of Cyclosporin A retains host defense against invasive pulmonary aspergillosis in a non-immunosuppressive murine model by preserving the myeloid cell population.

Wong SSW, Rasid O, Laskaris P, Fekkar A, Cavaillon JM, Steinbach WJ, Ibrahim-Granet O.

Virulence. 2017 Nov 17;8(8):1744-1752. doi: 10.1080/21505594.2017.1339007. Epub 2017 Jul 6.


Administration of Zinc Chelators Improves Survival of Mice Infected with Aspergillus fumigatus both in Monotherapy and in Combination with Caspofungin.

Laskaris P, Atrouni A, Calera JA, d'Enfert C, Munier-Lehmann H, Cavaillon JM, Latgé JP, Ibrahim-Granet O.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):5631-9. doi: 10.1128/AAC.00324-16. Print 2016 Oct.


Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor.

Gresnigt MS, Rekiki A, Rasid O, Savers A, Jouvion G, Dannaoui E, Parlato M, Fitting C, Brock M, Cavaillon JM, van de Veerdonk FL, Ibrahim-Granet O.

Sci Rep. 2016 May 24;6:26490. doi: 10.1038/srep26490.


Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge.

Savers A, Rasid O, Parlato M, Brock M, Jouvion G, Ryffel B, Cavaillon JM, Eberl G, Ibrahim-Granet O.

PLoS One. 2016 Apr 14;11(4):e0153829. doi: 10.1371/journal.pone.0153829. eCollection 2016.


Targeting zinc homeostasis to combat Aspergillus fumigatus infections.

Vicentefranqueira R, Amich J, Laskaris P, Ibrahim-Granet O, Latgé JP, Toledo H, Leal F, Calera JA.

Front Microbiol. 2015 Feb 27;6:160. doi: 10.3389/fmicb.2015.00160. eCollection 2015.


Assessment of efficacy of antifungals against Aspergillus fumigatus: value of real-time bioluminescence imaging.

Galiger C, Brock M, Jouvion G, Savers A, Parlato M, Ibrahim-Granet O.

Antimicrob Agents Chemother. 2013 Jul;57(7):3046-59. doi: 10.1128/AAC.01660-12. Epub 2013 Apr 15.


Murine infection models for Aspergillus terreus pulmonary aspergillosis reveal long-term persistence of conidia and liver degeneration.

Slesiona S, Ibrahim-Granet O, Olias P, Brock M, Jacobsen ID.

J Infect Dis. 2012 Apr 15;205(8):1268-77. doi: 10.1093/infdis/jis193.


DIGE enables the detection of a putative serum biomarker of fungal origin in a mouse model of invasive aspergillosis.

Fekkar A, Pionneau C, Brossas JY, Marinach-Patrice C, Snounou G, Brock M, Ibrahim-Granet O, Mazier D.

J Proteomics. 2012 May 17;75(9):2536-49. doi: 10.1016/j.jprot.2012.01.040. Epub 2012 Feb 17.


Duality of liver and kidney lesions after systemic infection of immunosuppressed and immunocompetent mice with Aspergillus fumigatus.

Jouvion G, Brock M, Droin-Bergère S, Ibrahim-Granet O.

Virulence. 2012 Jan-Feb;3(1):43-50. doi: 10.4161/viru.3.1.18654. Epub 2012 Jan 1.


The crucial role of the Aspergillus fumigatus siderophore system in interaction with alveolar macrophages.

Schrettl M, Ibrahim-Granet O, Droin S, Huerre M, Latgé JP, Haas H.

Microbes Infect. 2010 Nov;12(12-13):1035-41. doi: 10.1016/j.micinf.2010.07.005. Epub 2010 Jul 24.


In vivo bioluminescence imaging and histopathopathologic analysis reveal distinct roles for resident and recruited immune effector cells in defense against invasive aspergillosis.

Ibrahim-Granet O, Jouvion G, Hohl TM, Droin-Bergère S, Philippart F, Kim OY, Adib-Conquy M, Schwendener R, Cavaillon JM, Brock M.

BMC Microbiol. 2010 Apr 8;10:105. doi: 10.1186/1471-2180-10-105.


Bioluminescent Aspergillus fumigatus, a new tool for drug efficiency testing and in vivo monitoring of invasive aspergillosis.

Brock M, Jouvion G, Droin-Bergère S, Dussurget O, Nicola MA, Ibrahim-Granet O.

Appl Environ Microbiol. 2008 Nov;74(22):7023-35. doi: 10.1128/AEM.01288-08. Epub 2008 Sep 26.


Phagocytosis of Aspergillus fumigatus conidia by primary nasal epithelial cells in vitro.

Botterel F, Gross K, Ibrahim-Granet O, Khoufache K, Escabasse V, Coste A, Cordonnier C, Escudier E, Bretagne S.

BMC Microbiol. 2008 Jun 18;8:97. doi: 10.1186/1471-2180-8-97.


Methylcitrate synthase from Aspergillus fumigatus is essential for manifestation of invasive aspergillosis.

Ibrahim-Granet O, Dubourdeau M, Latgé JP, Ave P, Huerre M, Brakhage AA, Brock M.

Cell Microbiol. 2008 Jan;10(1):134-48.


The regulation of zinc homeostasis by the ZafA transcriptional activator is essential for Aspergillus fumigatus virulence.

Moreno MA, Ibrahim-Granet O, Vicentefranqueira R, Amich J, Ave P, Leal F, Latgé JP, Calera JA.

Mol Microbiol. 2007 Jun;64(5):1182-97.


Characterization of the SKN7 ortholog of Aspergillus fumigatus.

Lamarre C, Ibrahim-Granet O, Du C, Calderone R, Latgé JP.

Fungal Genet Biol. 2007 Jul;44(7):682-90. Epub 2007 Jan 30.


Aspergillus fumigatus does not require fatty acid metabolism via isocitrate lyase for development of invasive aspergillosis.

Schöbel F, Ibrahim-Granet O, Avé P, Latgé JP, Brakhage AA, Brock M.

Infect Immun. 2007 Mar;75(3):1237-44. Epub 2006 Dec 18.


Aspergillus fumigatus induces innate immune responses in alveolar macrophages through the MAPK pathway independently of TLR2 and TLR4.

Dubourdeau M, Athman R, Balloy V, Huerre M, Chignard M, Philpott DJ, Latgé JP, Ibrahim-Granet O.

J Immunol. 2006 Sep 15;177(6):3994-4001.


Interaction of Aspergillus fumigatus with the alveolar macrophage.

Dubourdeau M, Athman R, Balloy V, Philippe B, Sengmanivong L, Chignard M, Philpott DJ, Latgé JP, Ibrahim-Granet O.

Med Mycol. 2006 Sep 1;44(Supplement_1):S213-S217. doi: 10.1080/13693780600904900.


Glycosylphosphatidylinositol-anchored Ecm33p influences conidial cell wall biosynthesis in Aspergillus fumigatus.

Chabane S, Sarfati J, Ibrahim-Granet O, Du C, Schmidt C, Mouyna I, Prevost MC, Calderone R, Latgé JP.

Appl Environ Microbiol. 2006 May;72(5):3259-67.


Aspergillus fumigatus conidia inhibit tumour necrosis factor- or staurosporine-induced apoptosis in epithelial cells.

Berkova N, Lair-Fulleringer S, Féménia F, Huet D, Wagner MC, Gorna K, Tournier F, Ibrahim-Granet O, Guillot J, Chermette R, Boireau P, Latgé JP.

Int Immunol. 2006 Jan;18(1):139-50. Epub 2005 Dec 15.


Phosphatidylinositol-dependent phospholipases C Plc2 and Plc3 of Candida albicans are dispensable for morphogenesis and host-pathogen interaction.

Knechtle P, Goyard S, Brachat S, Ibrahim-Granet O, d'Enfert C.

Res Microbiol. 2005 Aug;156(7):822-9.


Killing of Aspergillus fumigatus by alveolar macrophages is mediated by reactive oxidant intermediates.

Philippe B, Ibrahim-Granet O, Prévost MC, Gougerot-Pocidalo MA, Sanchez Perez M, Van der Meeren A, Latgé JP.

Infect Immun. 2003 Jun;71(6):3034-42.


Phagocytosis and intracellular fate of Aspergillus fumigatus conidia in alveolar macrophages.

Ibrahim-Granet O, Philippe B, Boleti H, Boisvieux-Ulrich E, Grenet D, Stern M, Latgé JP.

Infect Immun. 2003 Feb;71(2):891-903.


Separation of proteases: old and new approaches.

Ibrahim-Granet O, Bertrand O.

J Chromatogr B Biomed Appl. 1996 Sep 20;684(1-2):239-63. Review.


Aspergillus fumigatus metalloproteinase that hydrolyses native collagen: purification by dye-binding chromatography.

Ibrahim-Granet O, Bertrand O, Debeaupuis JP, Planchenault T, Diaquin M, Dupont B.

Protein Expr Purif. 1994 Feb;5(1):84-8.


Heat-shock response in Fonsecaea pedrosoi, a pathogenic fungus.

Laurent-Winter C, Ibrahim-Granet O.

Can J Microbiol. 1992 Dec;38(12):1286-91.


Immunochemical characterisation of antigens and growth inhibition of Fonsecaea pedrosoi by species-specific IgG.

Ibrahim-Granet O, de Bièvre C, Jendoubi M.

J Med Microbiol. 1988 Jul;26(3):217-22.


Polymorphism in mitochondrial DNA of several Trichophyton rubrum isolates from clinical specimens.

de Bièvre C, Dauguet C, Nguyen VH, Ibrahim-Granet O.

Ann Inst Pasteur Microbiol. 1987 Nov-Dec;138(6):719-27.


Comparative electrophoresis, isoelectric focusing and numerical taxonomy of some isolates of Fonsecaea pedrosoi and allied fungi.

Ibrahim-Granet O, de Bievre C, Romain F, Letoffe S.

Sabouraudia. 1985 Aug;23(4):253-64.


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