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Fosmanogepix (APX001) is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis.

Alkhazraji S, Gebremariam T, Alqarihi A, Gu Y, Mamouei Z, Singh S, Wiederhold NP, Shaw KJ, Ibrahim AS.

Antimicrob Agents Chemother. 2019 Dec 9. pii: AAC.01735-19. doi: 10.1128/AAC.01735-19. [Epub ahead of print]


Detecting liver fibrosis using a machine learning-based approach to the quantification of the heart-induced deformation in tagged MR images.

Ahmed Y, Hussein RS, Basha TA, Khalifa AM, Ibrahim AS, Abdelmoaty AS, Abdella HM, Fahmy AS.

NMR Biomed. 2019 Nov 15:e4215. doi: 10.1002/nbm.4215. [Epub ahead of print]


Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium.

Cornely OA, Alastruey-Izquierdo A, Arenz D, Chen SCA, Dannaoui E, Hochhegger B, Hoenigl M, Jensen HE, Lagrou K, Lewis RE, Mellinghoff SC, Mer M, Pana ZD, Seidel D, Sheppard DC, Wahba R, Akova M, Alanio A, Al-Hatmi AMS, Arikan-Akdagli S, Badali H, Ben-Ami R, Bonifaz A, Bretagne S, Castagnola E, Chayakulkeeree M, Colombo AL, Corzo-León DE, Drgona L, Groll AH, Guinea J, Heussel CP, Ibrahim AS, Kanj SS, Klimko N, Lackner M, Lamoth F, Lanternier F, Lass-Floerl C, Lee DG, Lehrnbecher T, Lmimouni BE, Mares M, Maschmeyer G, Meis JF, Meletiadis J, Morrissey CO, Nucci M, Oladele R, Pagano L, Pasqualotto A, Patel A, Racil Z, Richardson M, Roilides E, Ruhnke M, Seyedmousavi S, Sidharthan N, Singh N, Sinko J, Skiada A, Slavin M, Soman R, Spellberg B, Steinbach W, Tan BH, Ullmann AJ, Vehreschild JJ, Vehreschild MJGT, Walsh TJ, White PL, Wiederhold NP, Zaoutis T, Chakrabarti A; Mucormycosis ECMM MSG Global Guideline Writing Group.

Lancet Infect Dis. 2019 Dec;19(12):e405-e421. doi: 10.1016/S1473-3099(19)30312-3. Epub 2019 Nov 5. Review.


Galactomannan is a Biomarker of Fosmanogepix (APX001) Efficacy in Treating Experimental Invasive Pulmonary Aspergillosis.

Gebremariam T, Alkhazraji S, Gu Y, Singh S, Alqarihi A, Shaw KJ, Ibrahim AS.

Antimicrob Agents Chemother. 2019 Nov 4. pii: AAC.01966-19. doi: 10.1128/AAC.01966-19. [Epub ahead of print]


Alkaline serine protease from the new halotolerant alkaliphilic Salipaludibacillus agaradhaerens strain AK-R: purification and properties.

Ibrahim ASS, Elbadawi YB, El-Tayeb MA, Al-Maary KS, Maany DAF, Ibrahim SSS, Elagib AA.

3 Biotech. 2019 Nov;9(11):391. doi: 10.1007/s13205-019-1928-9. Epub 2019 Oct 10.


Combined pulsed and thermal radiofrequency versus thermal radiofrequency alone in the treatment of recurrent trigeminal neuralgia after microvascular decompression: A double blinded comparative study.

Abdel-Rahman KA, Elawamy AM, Mostafa MF, Hasan WS, Herdan R, Osman NM, Ibrahim AS, Aly MG, Ali AS, Abodahab GM.

Eur J Pain. 2019 Sep 30. doi: 10.1002/ejp.1489. [Epub ahead of print]


Epidemiological and Clinical Profiles of Patients with Acute Respiratory Distress Syndrome Admitted to Medical Intensive Care in Qatar: A Retrospective Analysis of the Data Registry for the Year 2015.

Ibrahim AS, Akkari AM, Raza T, Hassan IF, Akbar A, Alatoum I.

Qatar Med J. 2019 Jul 30;2019(1):3. doi: 10.5339/qmj.2019.3. eCollection 2019.


The NDV-3A vaccine protects mice from multidrug resistant Candida auris infection.

Singh S, Uppuluri P, Mamouei Z, Alqarihi A, Elhassan H, French S, Lockhart SR, Chiller T, Edwards JE Jr, Ibrahim AS.

PLoS Pathog. 2019 Aug 5;15(8):e1007460. doi: 10.1371/journal.ppat.1007460. eCollection 2019 Aug.


A dual role of 12/15-lipoxygenase in LPS-induced acute renal inflammation and injury.

Elmarakby AA, Ibrahim AS, Katary MA, Elsherbiny NM, El-Shafey M, Abd-Elrazik AM, Abdelsayed RA, Maddipati KR, Al-Shabrawey M.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Nov;1864(11):1669-1680. doi: 10.1016/j.bbalip.2019.07.009. Epub 2019 Jul 23.


A Novel Dental Sealant Containing Dimethylaminohexadecyl Methacrylate Suppresses the Cariogenic Pathogenicity of Streptococcus mutans Biofilms.

Ibrahim MS, Ibrahim AS, Balhaddad AA, Weir MD, Lin NJ, Tay FR, Oates TW, Xu HHK, Melo MAS.

Int J Mol Sci. 2019 Jul 16;20(14). pii: E3491. doi: 10.3390/ijms20143491.


Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis.

Gebremariam T, Alkhazraji S, Soliman SSM, Gu Y, Jeon HH, Zhang L, French SW, Stevens DA, Edwards JE Jr, Filler SG, Uppuluri P, Ibrahim AS.

Sci Adv. 2019 Jun 12;5(6):eaaw1327. doi: 10.1126/sciadv.aaw1327. eCollection 2019 Jun.


Could Short-Term Perioperative High-Dose Atorvastatin Offer Antiarrhythmic and Cardio-Protective Effects in Rheumatic Valve Replacement Surgery?

Allah EA, Kamel EZ, Osman HM, Abd-Elshafy SK, Nabil F, Elmelegy TTH, Elkhayat H, Ibrahim AS, Minshawy AA.

J Cardiothorac Vasc Anesth. 2019 Dec;33(12):3340-3347. doi: 10.1053/j.jvca.2019.05.013. Epub 2019 May 17.


NDV-3A vaccination prevents C. albicans colonization of jugular vein catheters in mice.

Alqarihi A, Singh S, Edwards JE Jr, Ibrahim AS, Uppuluri P.

Sci Rep. 2019 Apr 17;9(1):6194. doi: 10.1038/s41598-019-42517-y.


Authors' Reply to the Letter to the Editor from Mukhdomi and Kendall.

Ibrahim AS.

Eur J Pain. 2019 Jul;23(6):1222. doi: 10.1002/ejp.1388. Epub 2019 Mar 25. No abstract available.


Meta-analysis comparing outcomes of different transoral surgical modalities in management of oropharyngeal carcinoma.

Ibrahim AS, Civantos FJ, Leibowitz JM, Thomas GR, Arnold DJ, Franzmann EJ, Nicolli EA, Lo K, Nemeth Z, Sargi ZB, Weed DT.

Head Neck. 2019 Jun;41(6):1656-1666. doi: 10.1002/hed.25647. Epub 2019 Jan 28.


Metabolic Profiling of Candida auris, a Newly-Emerging Multi-Drug Resistant Candida Species, by GC-MS.

Semreen MH, Soliman SSM, Saeed BQ, Alqarihi A, Uppuluri P, Ibrahim AS.

Molecules. 2019 Jan 22;24(3). pii: E399. doi: 10.3390/molecules24030399.


Lateral thoracic artery as recipient vessel for head and neck free flap reconstruction in the vessel depleted neck: A case report.

Ibrahim ASG, Kakarala K, Bur AM.

Microsurgery. 2019 Nov;39(8):748-752. doi: 10.1002/micr.30419. Epub 2019 Jan 21.


Three Dimensional (3D) Echocardiography as a Tool of Left Ventricular Assessment in Children with Dilated Cardiomyopathy: Comparison to Cardiac MRI.

Habeeb NM, Youssef OI, Elguindy WM, Ibrahim AS, Hussein WH.

Open Access Maced J Med Sci. 2018 Oct 25;6(12):2310-2315. doi: 10.3889/oamjms.2018.270. eCollection 2018 Dec 20.


Mentoring Researchers in Resource-Poor Countries: The Role of the Clinical Nurse Specialist as Mentor.

Ibrahim AS, Hartjes TM, Rivera L, Adebayo A, Pierre L, Scruth E.

Clin Nurse Spec. 2019 Jan/Feb;33(1):7-11. doi: 10.1097/NUR.0000000000000413. No abstract available.


A Controlled Impact of Optic Nerve as a New Model of Traumatic Optic Neuropathy in Mouse.

Ibrahim AS, Elmasry K, Wan M, Abdulmoneim S, Still A, Khan F, Khalil A, Saul A, Hoda MN, Al-Shabrawey M.

Invest Ophthalmol Vis Sci. 2018 Nov 1;59(13):5548-5557. doi: 10.1167/iovs.18-24773.


Author Correction: Iron restriction inside macrophages regulates pulmonary host defense against Rhizopus species.

Andrianaki AM, Kyrmizi I, Thanopoulou K, Baldin C, Drakos E, Soliman SSM, Shetty AC, McCracken C, Akoumianaki T, Stylianou K, Ioannou P, Pontikoglou C, Papadaki HA, Tzardi M, Belle V, Etienne E, Beauvais A, Samonis G, Kontoyiannis DP, Andreakos E, Bruno VM, Ibrahim AS, Chamilos G.

Nat Commun. 2018 Nov 22;9(1):5015. doi: 10.1038/s41467-018-07301-y.


Particle bombardment-mediated co-transformation of the Cht-2 gene in wheat and the associated changes in defense mechanisms in transgenic plants infected with Fusarium graminearum.

Hashem HA, Hassanein RA, Fahmy AH, Ibrahim AS, El Shihyh OM, Qaid EA.

Data Brief. 2018 Oct 16;21:1111-1118. doi: 10.1016/j.dib.2018.09.130. eCollection 2018 Dec.


APX001 Is Effective in the Treatment of Murine Invasive Pulmonary Aspergillosis.

Gebremariam T, Alkhazraji S, Alqarihi A, Jeon HH, Gu Y, Kapoor M, Shaw KJ, Ibrahim AS.

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01713-18. doi: 10.1128/AAC.01713-18. Print 2019 Feb.


Alexidine Dihydrochloride Has Broad-Spectrum Activities against Diverse Fungal Pathogens.

Mamouei Z, Alqarihi A, Singh S, Xu S, Mansour MK, Ibrahim AS, Uppuluri P.

mSphere. 2018 Oct 31;3(5). pii: e00539-18. doi: 10.1128/mSphere.00539-18.


Bioactive lipids and pathological retinal angiogenesis.

Elmasry K, Ibrahim AS, Abdulmoneim S, Al-Shabrawey M.

Br J Pharmacol. 2019 Jan;176(1):93-109. doi: 10.1111/bph.14507. Epub 2018 Nov 19. Review.


Inhibition of interleukin-6 trans-signaling prevents inflammation and endothelial barrier disruption in retinal endothelial cells.

Valle ML, Dworshak J, Sharma A, Ibrahim AS, Al-Shabrawey M, Sharma S.

Exp Eye Res. 2019 Jan;178:27-36. doi: 10.1016/j.exer.2018.09.009. Epub 2018 Sep 18.


Digoxin and clinical outcomes in the Global Rheumatic Heart Disease Registry.

Karthikeyan G, Devasenapathy N, Zühlke L, Engel ME, Rangarajan S, Teo KK, Mayosi BM, Yusuf S; Global Rheumatic Heart Disease Registry (REMEDY) Investigators.

Heart. 2019 Mar;105(5):363-369. doi: 10.1136/heartjnl-2018-313614. Epub 2018 Sep 12.


Iron restriction inside macrophages regulates pulmonary host defense against Rhizopus species.

Andrianaki AM, Kyrmizi I, Thanopoulou K, Baldin C, Drakos E, Soliman SSM, Shetty AC, McCracken C, Akoumianaki T, Stylianou K, Ioannou P, Pontikoglou C, Papadaki HA, Tzardi M, Belle V, Etienne E, Beauvais A, Samonis G, Kontoyiannis DP, Andreakos E, Bruno VM, Ibrahim AS, Chamilos G.

Nat Commun. 2018 Aug 20;9(1):3333. doi: 10.1038/s41467-018-05820-2. Erratum in: Nat Commun. 2018 Nov 22;9(1):5015.


Inhibition of EGFR Signaling Protects from Mucormycosis.

Watkins TN, Gebremariam T, Swidergall M, Shetty AC, Graf KT, Alqarihi A, Alkhazraji S, Alsaadi AI, Edwards VL, Filler SG, Ibrahim AS, Bruno VM.

MBio. 2018 Aug 14;9(4). pii: e01384-18. doi: 10.1128/mBio.01384-18.


PCR-Based Approach Targeting Mucorales-Specific Gene Family for Diagnosis of Mucormycosis.

Baldin C, Soliman SSM, Jeon HH, Alkhazraji S, Gebremariam T, Gu Y, Bruno VM, Cornely OA, Leather HL, Sugrue MW, Wingard JR, Stevens DA, Edwards JE Jr, Ibrahim AS.

J Clin Microbiol. 2018 Sep 25;56(10). pii: e00746-18. doi: 10.1128/JCM.00746-18. Print 2018 Oct.


Ultrasound-guided adductor canal block after arthroscopic anterior cruciate ligament reconstruction: Effect of adding dexamethasone to bupivacaine, a randomized controlled trial.

Ibrahim AS, Aly MG, Farrag WS, Gad El-Rab NA, Said HG, Saad AH.

Eur J Pain. 2019 Jan;23(1):135-141. doi: 10.1002/ejp.1292. Epub 2018 Aug 6.


Human Anti-Als3p Antibodies Are Surrogate Markers of NDV-3A Vaccine Efficacy Against Recurrent Vulvovaginal Candidiasis.

Uppuluri P, Singh S, Alqarihi A, Schmidt CS, Hennessey JP Jr, Yeaman MR, Filler SG, Edwards JE, Ibrahim AS.

Front Immunol. 2018 Jun 15;9:1349. doi: 10.3389/fimmu.2018.01349. eCollection 2018.


Effect of adding nalbuphine to intrathecal bupivacaine with morphine on postoperative nausea and vomiting and pruritus after elective cesarean delivery: a randomized double blinded study.

Ibrahim AS, Aly MG, Thabet ME, Abdelaziz MR.

Minerva Anestesiol. 2019 Mar;85(3):255-262. doi: 10.23736/S0375-9393.18.12751-9. Epub 2018 May 30.


Renal iron deposition by magnetic resonance imaging in pediatric β-thalassemia major patients: Relation to renal biomarkers, total body iron and chelation therapy.

ElAlfy MS, Khalil Elsherif NH, Ebeid FSE, Ismail EAR, Ahmed KA, Darwish YW, Ibrahim AS, Elghamry IRF, Shokrey NA, Alajeil DN.

Eur J Radiol. 2018 Jun;103:65-70. doi: 10.1016/j.ejrad.2018.04.007. Epub 2018 Apr 9.


Addressing the challenges of ECMO simulation.

Alinier G, Hassan IF, Alsalemi A, Al Disi M, Ait Hssain A, Labib A, Alhomsi Y, Bensaali F, Amira A, Ibrahim AS.

Perfusion. 2018 Oct;33(7):568-576. doi: 10.1177/0267659118777194. Epub 2018 May 23.


The Hyr1 protein from the fungus Candida albicans is a cross kingdom immunotherapeutic target for Acinetobacter bacterial infection.

Uppuluri P, Lin L, Alqarihi A, Luo G, Youssef EG, Alkhazraji S, Yount NY, Ibrahim BA, Bolaris MA, Edwards JE Jr, Swidergall M, Filler SG, Yeaman MR, Ibrahim AS.

PLoS Pathog. 2018 May 10;14(5):e1007056. doi: 10.1371/journal.ppat.1007056. eCollection 2018 May.


Possible association of ghrelin/obestatin balance with cardiometabolic risk in obese subjects with Helicobacter pylori.

Ibrahim AS, Eldeeb MM, Salama OA, Rashad MM, Okasha KM.

Endocr Regul. 2018 Apr 1;52(2):101-109. doi: 10.2478/enr-2018-0012.


A Fungal Immunotherapeutic Vaccine (NDV-3A) for Treatment of Recurrent Vulvovaginal Candidiasis-A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial.

Edwards JE Jr, Schwartz MM, Schmidt CS, Sobel JD, Nyirjesy P, Schodel F, Marchus E, Lizakowski M, DeMontigny EA, Hoeg J, Holmberg T, Cooke MT, Hoover K, Edwards L, Jacobs M, Sussman S, Augenbraun M, Drusano M, Yeaman MR, Ibrahim AS, Filler SG, Hennessey JP Jr.

Clin Infect Dis. 2018 Jun 1;66(12):1928-1936. doi: 10.1093/cid/ciy185.


Microbial Oxidation of the Fusidic Acid Side Chain by Cunninghamella echinulata.

Ibrahim AS, Elokely KM, Ferreira D, Ragab AE.

Molecules. 2018 Apr 21;23(4). pii: E970. doi: 10.3390/molecules23040970.


Semi-quantitative Cough Strength Score as a Predictor for Extubation Outcome in Traumatic Brain Injury: A Prospective Observational Study.

Ibrahim AS, Aly MG, Abdel-Rahman KA, Mohamed MA, Mehany MM, Aziz EM.

Neurocrit Care. 2018 Oct;29(2):273-279. doi: 10.1007/s12028-018-0539-3.


In Situ Validation of the Endothelial Cell Receptor GRP78 in a Case of Rhinocerebral Mucormycosis.

Shumilov E, Bacher U, Perske C, Mohr A, Eiffert H, Hasenkamp J, Trümper L, Wulf GG, Ströbel P, Ibrahim AS, Venkataramani V.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e00172-18. doi: 10.1128/AAC.00172-18. Print 2018 May. No abstract available.


MRI for the diagnosis of cardiac and liver iron overload in patients with transfusion-dependent thalassemia: An algorithm to guide clinical use when availability is limited.

Viprakasit V, Ajlan A, Aydinok Y, Al Ebadi BAA, Dewedar H, Ibrahim AS, Ragab L, Trad O, Wataify AS, Wong LLL, Taher AT.

Am J Hematol. 2018 Jun;93(6):E135-E137. doi: 10.1002/ajh.25075. Epub 2018 Mar 15. No abstract available.


Role of endoplasmic reticulum stress in 12/15-lipoxygenase-induced retinal microvascular dysfunction in a mouse model of diabetic retinopathy.

Elmasry K, Ibrahim AS, Saleh H, Elsherbiny N, Elshafey S, Hussein KA, Al-Shabrawey M.

Diabetologia. 2018 May;61(5):1220-1232. doi: 10.1007/s00125-018-4560-z. Epub 2018 Feb 21.


Calli Essential Oils Synergize with Lawsone against Multidrug Resistant Pathogens.

Soliman SSM, Alsaadi AI, Youssef EG, Khitrov G, Noreddin AM, Husseiny MI, Ibrahim AS.

Molecules. 2017 Dec 20;22(12). pii: E2223. doi: 10.3390/molecules22122223.


The mucormycete-host interface.

Ibrahim AS, Voelz K.

Curr Opin Microbiol. 2017 Dec;40:40-45. doi: 10.1016/j.mib.2017.10.010. Epub 2017 Nov 4. Review.


Hyperhomocysteinemia Alters Retinal Endothelial Cells Barrier Function and Angiogenic Potential via Activation of Oxidative Stress.

Mohamed R, Sharma I, Ibrahim AS, Saleh H, Elsherbiny NM, Fulzele S, Elmasry K, Smith SB, Al-Shabrawey M, Tawfik A.

Sci Rep. 2017 Sep 20;7(1):11952. doi: 10.1038/s41598-017-09731-y.


Oncologic outcomes of KTP laser surgery versus radiation for T1 glottic carcinoma.

Ahmed J, Ibrahim ASG, M Freedman L, Rosow DE.

Laryngoscope. 2018 May;128(5):1052-1056. doi: 10.1002/lary.26853. Epub 2017 Sep 12.


Molecular mechanisms of mucormycosis-The bitter and the sweet.

Baldin C, Ibrahim AS.

PLoS Pathog. 2017 Aug 3;13(8):e1006408. doi: 10.1371/journal.ppat.1006408. eCollection 2017 Aug. Review. No abstract available.

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