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Items: 1 to 50 of 145

1.

ALK4 coordinates extracellular and intrinsic signals to regulate development of cortical somatostatin interneurons.

Göngrich C, Krapacher FA, Munguba H, Fernández-Suárez D, Andersson A, Hjerling-Leffler J, Ibáñez CF.

J Cell Biol. 2019 Nov 1. pii: jcb.201905002. doi: 10.1083/jcb.201905002. [Epub ahead of print]

PMID:
31676717
2.

Correction: MAG induces apoptosis in cerebellar granule neurons through p75NTR demarcating granule layer/white matter boundary.

Fernández-Suárez D, Krapacher FA, Andersson A, Ibáñez CF, Kisiswa L.

Cell Death Dis. 2019 Oct 31;10(11):824. doi: 10.1038/s41419-019-2058-3.

3.

MAG induces apoptosis in cerebellar granule neurons through p75NTR demarcating granule layer/white matter boundary.

Fernández-Suárez D, Krapacher FA, Andersson A, Ibáñez CF, Kisiswa L.

Cell Death Dis. 2019 Sep 30;10(10):732. doi: 10.1038/s41419-019-1970-x. Erratum in: Cell Death Dis. 2019 Oct 31;10(11):824.

4.

The p75 Neurotrophin Receptor Is an Essential Mediator of Impairments in Hippocampal-Dependent Associative Plasticity and Memory Induced by Sleep Deprivation.

Wong LW, Tann JY, Ibanez CF, Sajikumar S.

J Neurosci. 2019 Jul 10;39(28):5452-5465. doi: 10.1523/JNEUROSCI.2876-18.2019. Epub 2019 May 13.

PMID:
31085607
5.

Death domain of p75 neurotrophin receptor: a structural perspective on an intracellular signalling hub.

Yuan W, Ibáñez CF, Lin Z.

Biol Rev Camb Philos Soc. 2019 Aug;94(4):1282-1293. doi: 10.1111/brv.12502. Epub 2019 Feb 14.

PMID:
30762293
6.

Abnormal TDP-43 function impairs activity-dependent BDNF secretion, synaptic plasticity, and cognitive behavior through altered Sortilin splicing.

Tann JY, Wong LW, Sajikumar S, Ibáñez CF.

EMBO J. 2019 Mar 1;38(5). pii: e100989. doi: 10.15252/embj.2018100989. Epub 2019 Jan 28.

PMID:
30692134
8.

A Small Molecule Targeting the Transmembrane Domain of Death Receptor p75NTR Induces Melanoma Cell Death and Reduces Tumor Growth.

Goh ETH, Lin Z, Ahn BY, Lopes-Rodrigues V, Dang NH, Salim S, Berger B, Dymock B, Senger DL, Ibáñez CF.

Cell Chem Biol. 2018 Dec 20;25(12):1485-1494.e5. doi: 10.1016/j.chembiol.2018.09.007. Epub 2018 Oct 4.

PMID:
30293939
9.

RIP2 Gates TRAF6 Interaction with Death Receptor p75NTR to Regulate Cerebellar Granule Neuron Survival.

Kisiswa L, Fernández-Suárez D, Sergaki MC, Ibáñez CF.

Cell Rep. 2018 Jul 24;24(4):1013-1024. doi: 10.1016/j.celrep.2018.06.098.

10.

Cell-autonomous role of GFRα1 in the development of olfactory bulb GABAergic interneurons.

Zechel S, Fernandez-Suarez D, Ibáñez CF.

Biol Open. 2018 May 18;7(5). pii: bio033753. doi: 10.1242/bio.033753.

11.

Compromised Survival of Cerebellar Molecular Layer Interneurons Lacking GDNF Receptors GFRα1 or RET Impairs Normal Cerebellar Motor Learning.

Sergaki MC, López-Ramos JC, Stagkourakis S, Gruart A, Broberger C, Delgado-García JM, Ibáñez CF.

Cell Rep. 2017 Jun 6;19(10):1977-1986. doi: 10.1016/j.celrep.2017.05.030.

12.

GFRα1 Regulates Purkinje Cell Migration by Counteracting NCAM Function.

Sergaki MC, Ibáñez CF.

Cell Rep. 2017 Jan 10;18(2):367-379. doi: 10.1016/j.celrep.2016.12.039.

13.

Thalamo-cortical axons regulate the radial dispersion of neocortical GABAergic interneurons.

Zechel S, Nakagawa Y, Ibáñez CF.

Elife. 2016 Dec 9;5. pii: e20770. doi: 10.7554/eLife.20770.

14.

Death Domain Signaling by Disulfide-Linked Dimers of the p75 Neurotrophin Receptor Mediates Neuronal Death in the CNS.

Tanaka K, Kelly CE, Goh KY, Lim KB, Ibáñez CF.

J Neurosci. 2016 May 18;36(20):5587-95. doi: 10.1523/JNEUROSCI.4536-15.2016.

15.

Biology of GDNF and its receptors - Relevance for disorders of the central nervous system.

Ibáñez CF, Andressoo JO.

Neurobiol Dis. 2017 Jan;97(Pt B):80-89. doi: 10.1016/j.nbd.2016.01.021. Epub 2016 Jan 29. Review.

PMID:
26829643
16.

Structural basis of death domain signaling in the p75 neurotrophin receptor.

Lin Z, Tann JY, Goh ET, Kelly C, Lim KB, Gao JF, Ibanez CF.

Elife. 2015 Dec 8;4:e11692. doi: 10.7554/eLife.11692.

17.

Neuron-type-specific signaling by the p75NTR death receptor is regulated by differential proteolytic cleavage.

Vicario A, Kisiswa L, Tann JY, Kelly CE, Ibáñez CF.

J Cell Sci. 2015 Apr 15;128(8):1507-17. doi: 10.1242/jcs.161745. Epub 2015 Feb 26.

18.

Topographical transcriptome mapping of the mouse medial ganglionic eminence by spatially resolved RNA-seq.

Zechel S, Zajac P, Lönnerberg P, Ibáñez CF, Linnarsson S.

Genome Biol. 2014;15(10):486.

19.

Adipocyte ALK7 links nutrient overload to catecholamine resistance in obesity.

Guo T, Marmol P, Moliner A, Björnholm M, Zhang C, Shokat KM, Ibanez CF.

Elife. 2014 Aug 25;3:e03245. doi: 10.7554/eLife.03245.

20.

Differential regulation of mouse pancreatic islet insulin secretion and Smad proteins by activin ligands.

Wu H, Mezghenna K, Marmol P, Guo T, Moliner A, Yang SN, Berggren PO, Ibáñez CF.

Diabetologia. 2014 Jan;57(1):148-56. doi: 10.1007/s00125-013-3079-6. Epub 2013 Oct 17.

PMID:
24132781
21.

Structure and physiology of the RET receptor tyrosine kinase.

Ibáñez CF.

Cold Spring Harb Perspect Biol. 2013 Feb 1;5(2). pii: a009134. doi: 10.1101/cshperspect.a009134. Review.

22.

Genetic dissection of neurotrophin signaling through the p75 neurotrophin receptor.

Charalampopoulos I, Vicario A, Pediaditakis I, Gravanis A, Simi A, Ibáñez CF.

Cell Rep. 2012 Dec 27;2(6):1563-70. doi: 10.1016/j.celrep.2012.11.009. Epub 2012 Dec 20.

23.

Critical role of GFRα1 in the development and function of the main olfactory system.

Marks C, Belluscio L, Ibáñez CF.

J Neurosci. 2012 Nov 28;32(48):17306-20. doi: 10.1523/JNEUROSCI.1522-12.2012.

24.

Neuroendocrine control of female reproductive function by the activin receptor ALK7.

Sandoval-Guzmán T, Göngrich C, Moliner A, Guo T, Wu H, Broberger C, Ibáñez CF.

FASEB J. 2012 Dec;26(12):4966-76. doi: 10.1096/fj.11-199059. Epub 2012 Sep 5.

PMID:
22954591
25.

p75 neurotrophin receptor signaling in nervous system injury and degeneration: paradox and opportunity.

Ibáñez CF, Simi A.

Trends Neurosci. 2012 Jul;35(7):431-40. doi: 10.1016/j.tins.2012.03.007. Epub 2012 Apr 13. Review.

PMID:
22503537
26.

MET signaling in GABAergic neuronal precursors of the medial ganglionic eminence restricts GDNF activity in cells that express GFRα1 and a new transmembrane receptor partner.

Perrinjaquet M, Sjöstrand D, Moliner A, Zechel S, Lamballe F, Maina F, Ibáñez CF.

J Cell Sci. 2011 Aug 15;124(Pt 16):2797-805. doi: 10.1242/jcs.083717.

27.

Protein-tyrosine phosphatase SHP2 contributes to GDNF neurotrophic activity through direct binding to phospho-Tyr687 in the RET receptor tyrosine kinase.

Perrinjaquet M, Vilar M, Ibáñez CF.

J Biol Chem. 2010 Oct 8;285(41):31867-75. doi: 10.1074/jbc.M110.144923. Epub 2010 Aug 3.

28.

Beyond the cell surface: new mechanisms of receptor function.

Ibáñez CF.

Biochem Biophys Res Commun. 2010 May 21;396(1):24-7. doi: 10.1016/j.bbrc.2010.01.136. Review.

PMID:
20494105
29.

Assembly and activation of neurotrophic factor receptor complexes.

Simi A, Ibáñez CF.

Dev Neurobiol. 2010 Apr;70(5):323-31. doi: 10.1002/dneu.20773. Review.

30.

Regionalized loss of parvalbumin interneurons in the cerebral cortex of mice with deficits in GFRalpha1 signaling.

Canty AJ, Dietze J, Harvey M, Enomoto H, Milbrandt J, Ibáñez CF.

J Neurosci. 2009 Aug 26;29(34):10695-705. doi: 10.1523/JNEUROSCI.2658-09.2009.

31.

Ligand-independent signaling by disulfide-crosslinked dimers of the p75 neurotrophin receptor.

Vilar M, Charalampopoulos I, Kenchappa RS, Reversi A, Klos-Applequist JM, Karaca E, Simi A, Spuch C, Choi S, Friedman WJ, Ericson J, Schiavo G, Carter BD, Ibáñez CF.

J Cell Sci. 2009 Sep 15;122(Pt 18):3351-7. doi: 10.1242/jcs.055061. Epub 2009 Aug 25.

32.

Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers.

Vilar M, Charalampopoulos I, Kenchappa RS, Simi A, Karaca E, Reversi A, Choi S, Bothwell M, Mingarro I, Friedman WJ, Schiavo G, Bastiaens PI, Verveer PJ, Carter BD, Ibáñez CF.

Neuron. 2009 Apr 16;62(1):72-83. doi: 10.1016/j.neuron.2009.02.020.

33.

Signalling mechanisms.

Ibanez CF, Häusser M.

Curr Opin Neurobiol. 2008 Jun;18(3):229-31. No abstract available.

PMID:
19180740
34.

Catecholaminergic neuron survival: getting hooked on GDNF.

Ibáñez CF.

Nat Neurosci. 2008 Jul;11(7):735-6. doi: 10.1038/nn0708-735. No abstract available.

PMID:
18575468
35.

Optimized mouse ES cell culture system by suspension growth in a fully defined medium.

Andäng M, Moliner A, Doege CA, Ibañez CF, Ernfors P.

Nat Protoc. 2008;3(6):1013-7. doi: 10.1038/nprot.2008.65.

PMID:
18536648
36.

Growth/differentiation factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesity.

Andersson O, Korach-Andre M, Reissmann E, Ibáñez CF, Bertolino P.

Proc Natl Acad Sci U S A. 2008 May 20;105(20):7252-6. doi: 10.1073/pnas.0800272105. Epub 2008 May 14.

37.

Activin B receptor ALK7 is a negative regulator of pancreatic beta-cell function.

Bertolino P, Holmberg R, Reissmann E, Andersson O, Berggren PO, Ibáñez CF.

Proc Natl Acad Sci U S A. 2008 May 20;105(20):7246-51. doi: 10.1073/pnas.0801285105. Epub 2008 May 14.

38.

Mouse embryonic stem cell-derived spheres with distinct neurogenic potentials.

Moliner A, Enfors P, Ibáñez CF, Andäng M.

Stem Cells Dev. 2008 Apr;17(2):233-43. doi: 10.1089/scd.2007.0211.

PMID:
18447639
39.

Insights into GFRalpha1 regulation of neural cell adhesion molecule (NCAM) function from structure-function analysis of the NCAM/GFRalpha1 receptor complex.

Sjöstrand D, Ibáñez CF.

J Biol Chem. 2008 May 16;283(20):13792-8. doi: 10.1074/jbc.M800283200. Epub 2008 Mar 19.

40.

Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation.

Andäng M, Hjerling-Leffler J, Moliner A, Lundgren TK, Castelo-Branco G, Nanou E, Pozas E, Bryja V, Halliez S, Nishimaru H, Wilbertz J, Arenas E, Koltzenburg M, Charnay P, El Manira A, Ibañez CF, Ernfors P.

Nature. 2008 Jan 24;451(7177):460-4. doi: 10.1038/nature06488. Epub 2008 Jan 9.

PMID:
18185516
41.

Message in a bottle: long-range retrograde signaling in the nervous system.

Ibáñez CF.

Trends Cell Biol. 2007 Nov;17(11):519-28. Epub 2007 Oct 29. Review.

PMID:
18029183
42.

Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development.

Andersson O, Bertolino P, Ibáñez CF.

Dev Biol. 2007 Nov 15;311(2):500-11. Epub 2007 Sep 14.

43.

Hierarchical control of sensory neuron development by neurotrophic factors.

Ibáñez CF, Ernfors P.

Neuron. 2007 Jun 7;54(5):673-5. Review.

44.

Disruption of the GDNF binding site in NCAM dissociates ligand binding and homophilic cell adhesion.

Sjöstrand D, Carlsson J, Paratcha G, Persson B, Ibáñez CF.

J Biol Chem. 2007 Apr 27;282(17):12734-40. Epub 2007 Feb 23.

45.

GDNF and GFRalpha1 promote formation of neuronal synapses by ligand-induced cell adhesion.

Ledda F, Paratcha G, Sandoval-Guzmán T, Ibáñez CF.

Nat Neurosci. 2007 Mar;10(3):293-300. Epub 2007 Feb 18.

PMID:
17310246
46.

Structure and chemical inhibition of the RET tyrosine kinase domain.

Knowles PP, Murray-Rust J, Kjaer S, Scott RP, Hanrahan S, Santoro M, Ibáñez CF, McDonald NQ.

J Biol Chem. 2006 Nov 3;281(44):33577-87. Epub 2006 Aug 23.

47.
48.

Self-association of the transmembrane domain of RET underlies oncogenic activation by MEN2A mutations.

Kjaer S, Kurokawa K, Perrinjaquet M, Abrescia C, Ibáñez CF.

Oncogene. 2006 Nov 9;25(53):7086-95. Epub 2006 May 29.

PMID:
16732321
49.

Synergistic interaction between Gdf1 and Nodal during anterior axis development.

Andersson O, Reissmann E, Jörnvall H, Ibáñez CF.

Dev Biol. 2006 May 15;293(2):370-81. Epub 2006 Mar 27.

50.

Bex1, a novel interactor of the p75 neurotrophin receptor, links neurotrophin signaling to the cell cycle.

Vilar M, Murillo-Carretero M, Mira H, Magnusson K, Besset V, Ibáñez CF.

EMBO J. 2006 Mar 22;25(6):1219-30. Epub 2006 Feb 23.

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