Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 94


A two-component protease in Methylorubrum extorquens with high activity toward the peptide precursor of the redox cofactor pyrroloquinoline quinone.

Martins AM, Latham JA, Martel PJ, Barr I, Iavarone AT, Klinman JP.

J Biol Chem. 2019 Aug 19. pii: jbc.RA119.009684. doi: 10.1074/jbc.RA119.009684. [Epub ahead of print]


Kinetic Characterization of the C-H Activation Step for the Lipoxygenase from the Pathogenic Fungus Magnaporthe oryzae: Impact of N-Linked Glycosylation.

Kostenko A, Ray K, Iavarone AT, Offenbacher AR.

Biochemistry. 2019 Jul 23;58(29):3193-3203. doi: 10.1021/acs.biochem.9b00467. Epub 2019 Jul 10.


Discovery of Hydroxylase Activity for PqqB Provides a Missing Link in the Pyrroloquinoline Quinone Biosynthetic Pathway.

Koehn EM, Latham JA, Armand T, Evans RL 3rd, Tu X, Wilmot CM, Iavarone AT, Klinman JP.

J Am Chem Soc. 2019 Mar 13;141(10):4398-4405. doi: 10.1021/jacs.8b13453. Epub 2019 Feb 27.


Oxidative Pathways of Deoxyribose and Deoxyribonate Catabolism.

Price MN, Ray J, Iavarone AT, Carlson HK, Ryan EM, Malmstrom RR, Arkin AP, Deutschbauer AM.

mSystems. 2019 Feb 5;4(1). pii: e00297-18. doi: 10.1128/mSystems.00297-18. eCollection 2019 Jan-Feb.


A Functional Mini-Integrase in a Two-Protein-type V-C CRISPR System.

Wright AV, Wang JY, Burstein D, Harrington LB, Paez-Espino D, Kyrpides NC, Iavarone AT, Banfield JF, Doudna JA.

Mol Cell. 2019 Feb 21;73(4):727-737.e3. doi: 10.1016/j.molcel.2018.12.015. Epub 2019 Jan 29.


Biotransformation of AFFF Component 6:2 Fluorotelomer Thioether Amido Sulfonate Generates 6:2 Fluorotelomer Thioether Carboxylate under Sulfate-Reducing Conditions.

Yi S, Harding-Marjanovic KC, Houtz EF, Gao Y, Lawrence JE, Nichiporuk RV, Iavarone AT, Zhuang WQ, Hansen M, Field JA, Sedlak DL, Alvarez-Cohen L.

Environ Sci Technol Lett. 2018 May 8;5(5):283-288. doi: 10.1021/acs.estlett.8b00148. Epub 2018 Apr 4.


A unique supramolecular organization of photosystem I in the moss Physcomitrella patens.

Iwai M, Grob P, Iavarone AT, Nogales E, Niyogi KK.

Nat Plants. 2018 Nov;4(11):904-909. doi: 10.1038/s41477-018-0271-1. Epub 2018 Oct 29.


A flavin-based extracellular electron transfer mechanism in diverse Gram-positive bacteria.

Light SH, Su L, Rivera-Lugo R, Cornejo JA, Louie A, Iavarone AT, Ajo-Franklin CM, Portnoy DA.

Nature. 2018 Oct;562(7725):140-144. doi: 10.1038/s41586-018-0498-z. Epub 2018 Sep 12.


Dissimilatory Sulfate Reduction Under High Pressure by Desulfovibrio alaskensis G20.

Williamson AJ, Carlson HK, Kuehl JV, Huang LL, Iavarone AT, Deutschbauer A, Coates JD.

Front Microbiol. 2018 Jul 9;9:1465. doi: 10.3389/fmicb.2018.01465. eCollection 2018.


Reactivity of O2 versus H2O2 with polysaccharide monooxygenases.

Hangasky JA, Iavarone AT, Marletta MA.

Proc Natl Acad Sci U S A. 2018 May 8;115(19):4915-4920. doi: 10.1073/pnas.1801153115. Epub 2018 Apr 23.


Mapping the H-NOX/HK Binding Interface in Vibrio cholerae by Hydrogen/Deuterium Exchange Mass Spectrometry.

Guo Y, Iavarone AT, Cooper MM, Marletta MA.

Biochemistry. 2018 Mar 20;57(11):1779-1789. doi: 10.1021/acs.biochem.8b00027. Epub 2018 Feb 27.


Characterization of Chlamydomonas reinhardtii Core Histones by Top-Down Mass Spectrometry Reveals Unique Algae-Specific Variants and Post-Translational Modifications.

Khan A, Eikani CK, Khan H, Iavarone AT, Pesavento JJ.

J Proteome Res. 2018 Jan 5;17(1):23-32. doi: 10.1021/acs.jproteome.7b00780. Epub 2017 Dec 8.


Hydrogen-deuterium exchange reveals long-range dynamical allostery in soybean lipoxygenase.

Offenbacher AR, Iavarone AT, Klinman JP.

J Biol Chem. 2018 Jan 26;293(4):1138-1148. doi: 10.1074/jbc.M117.817197. Epub 2017 Nov 30.


Regulation of nitric oxide signaling by formation of a distal receptor-ligand complex.

Guo Y, Suess DLM, Herzik MA Jr, Iavarone AT, Britt RD, Marletta MA.

Nat Chem Biol. 2017 Dec;13(12):1216-1221. doi: 10.1038/nchembio.2488. Epub 2017 Oct 2.


Hydrogen-Deuterium Exchange of Lipoxygenase Uncovers a Relationship between Distal, Solvent Exposed Protein Motions and the Thermal Activation Barrier for Catalytic Proton-Coupled Electron Tunneling.

Offenbacher AR, Hu S, Poss EM, Carr CAM, Scouras AD, Prigozhin DM, Iavarone AT, Palla A, Alber T, Fraser JS, Klinman JP.

ACS Cent Sci. 2017 Jun 28;3(6):570-579. doi: 10.1021/acscentsci.7b00142. Epub 2017 Jun 9.


Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics.

Spiciarich DR, Nolley R, Maund SL, Purcell SC, Herschel J, Iavarone AT, Peehl DM, Bertozzi CR.

Angew Chem Int Ed Engl. 2017 Jul 24;56(31):8992-8997. doi: 10.1002/anie.201701424. Epub 2017 Jun 26.


Correction: RNA and DNA Targeting by a Reconstituted Thermus thermophilus Type III-A CRISPR-Cas System.

Liu TY, Iavarone AT, Doudna JA.

PLoS One. 2017 Apr 6;12(4):e0175612. doi: 10.1371/journal.pone.0175612. eCollection 2017.


Oncometabolite D-2-Hydroxyglutarate enhances gene silencing through inhibition of specific H3K36 histone demethylases.

Janke R, Iavarone AT, Rine J.

Elife. 2017 Mar 27;6. pii: e22451. doi: 10.7554/eLife.22451.


Development of IsoTaG, a Chemical Glycoproteomics Technique for Profiling Intact N- and O-Glycopeptides from Whole Cell Proteomes.

Woo CM, Felix A, Byrd WE, Zuegel DK, Ishihara M, Azadi P, Iavarone AT, Pitteri SJ, Bertozzi CR.

J Proteome Res. 2017 Apr 7;16(4):1706-1718. doi: 10.1021/acs.jproteome.6b01053. Epub 2017 Feb 28.


Redox-based reagents for chemoselective methionine bioconjugation.

Lin S, Yang X, Jia S, Weeks AM, Hornsby M, Lee PS, Nichiporuk RV, Iavarone AT, Wells JA, Toste FD, Chang CJ.

Science. 2017 Feb 10;355(6325):597-602. doi: 10.1126/science.aal3316.


Nitric Oxide-Induced Conformational Changes Govern H-NOX and Histidine Kinase Interaction and Regulation in Shewanella oneidensis.

Rao M, Herzik MA Jr, Iavarone AT, Marletta MA.

Biochemistry. 2017 Mar 7;56(9):1274-1284. doi: 10.1021/acs.biochem.6b01133. Epub 2017 Feb 21.


Activity of the Pore-Forming Virulence Factor Listeriolysin O Is Reversibly Inhibited by Naturally Occurring S-Glutathionylation.

Portman JL, Huang Q, Reniere ML, Iavarone AT, Portnoy DA.

Infect Immun. 2017 Mar 23;85(4). pii: e00959-16. doi: 10.1128/IAI.00959-16. Print 2017 Apr.


RNA and DNA Targeting by a Reconstituted Thermus thermophilus Type III-A CRISPR-Cas System.

Liu TY, Iavarone AT, Doudna JA.

PLoS One. 2017 Jan 23;12(1):e0170552. doi: 10.1371/journal.pone.0170552. eCollection 2017. Erratum in: PLoS One. 2017 Apr 6;12 (4):e0175612.


Using lysine adducts of human serum albumin to investigate the disposition of exogenous formaldehyde in human blood.

Regazzoni LG, Grigoryan H, Ji Z, Chen X, Daniels SI, Huang D, Sanchez S, Tang N, Sillé FC, Iavarone AT, Williams ER, Zhang L, Rappaport SM.

Toxicol Lett. 2017 Feb 15;268:26-35. doi: 10.1016/j.toxlet.2017.01.002. Epub 2017 Jan 16.


Identification of Glutaminyl Cyclase Genes Involved in Pyroglutamate Modification of Fungal Lignocellulolytic Enzymes.

Wu VW, Dana CM, Iavarone AT, Clark DS, Glass NL.

MBio. 2017 Jan 17;8(1). pii: e02231-16. doi: 10.1128/mBio.02231-16.


Profiling the Serum Albumin Cys34 Adductome of Solid Fuel Users in Xuanwei and Fuyuan, China.

Lu SS, Grigoryan H, Edmands WM, Hu W, Iavarone AT, Hubbard A, Rothman N, Vermeulen R, Lan Q, Rappaport SM.

Environ Sci Technol. 2017 Jan 3;51(1):46-57. doi: 10.1021/acs.est.6b03955. Epub 2016 Dec 12.


Adductomics Pipeline for Untargeted Analysis of Modifications to Cys34 of Human Serum Albumin.

Grigoryan H, Edmands W, Lu SS, Yano Y, Regazzoni L, Iavarone AT, Williams ER, Rappaport SM.

Anal Chem. 2016 Nov 1;88(21):10504-10512. Epub 2016 Oct 10.


Promiscuous Diffusible Signal Factor Production and Responsiveness of the Xylella fastidiosa Rpf System.

Ionescu M, Yokota K, Antonova E, Garcia A, Beaulieu E, Hayes T, Iavarone AT, Lindow SE.

MBio. 2016 Jul 19;7(4). pii: e01054-16. doi: 10.1128/mBio.01054-16.


Magnetite Biomineralization in Magnetospirillum magneticum Is Regulated by a Switch-like Behavior in the HtrA Protease MamE.

Hershey DM, Browne PJ, Iavarone AT, Teyra J, Lee EH, Sidhu SS, Komeili A.

J Biol Chem. 2016 Aug 19;291(34):17941-52. doi: 10.1074/jbc.M116.731000. Epub 2016 Jun 14.


Evaluating Ultra-long-Chain Fatty Acids as Biomarkers of Colorectal Cancer Risk.

Perttula K, Edmands WM, Grigoryan H, Cai X, Iavarone AT, Gunter MJ, Naccarati A, Polidoro S, Hubbard A, Vineis P, Rappaport SM.

Cancer Epidemiol Biomarkers Prev. 2016 Aug;25(8):1216-23. doi: 10.1158/1055-9965.EPI-16-0204. Epub 2016 Jun 2.


Unconventional endocannabinoid signaling governs sperm activation via the sex hormone progesterone.

Miller MR, Mannowetz N, Iavarone AT, Safavi R, Gracheva EO, Smith JF, Hill RZ, Bautista DM, Kirichok Y, Lishko PV.

Science. 2016 Apr 29;352(6285):555-9. doi: 10.1126/science.aad6887. Epub 2016 Mar 17.


Demonstration That the Radical S-Adenosylmethionine (SAM) Enzyme PqqE Catalyzes de Novo Carbon-Carbon Cross-linking within a Peptide Substrate PqqA in the Presence of the Peptide Chaperone PqqD.

Barr I, Latham JA, Iavarone AT, Chantarojsiri T, Hwang JD, Klinman JP.

J Biol Chem. 2016 Apr 22;291(17):8877-84. doi: 10.1074/jbc.C115.699918. Epub 2016 Mar 8.


Targeted Lipid Profiling Discovers Plasma Biomarkers of Acute Brain Injury.

Sheth SA, Iavarone AT, Liebeskind DS, Won SJ, Swanson RA.

PLoS One. 2015 Jun 15;10(6):e0129735. doi: 10.1371/journal.pone.0129735. eCollection 2015.


Synthetic and Evolutionary Construction of a Chlorate-Reducing Shewanella oneidensis MR-1.

Clark IC, Melnyk RA, Youngblut MD, Carlson HK, Iavarone AT, Coates JD.

MBio. 2015 May 19;6(3):e00282-15. doi: 10.1128/mBio.00282-15.


Novel mechanism for scavenging of hypochlorite involving a periplasmic methionine-rich Peptide and methionine sulfoxide reductase.

Melnyk RA, Youngblut MD, Clark IC, Carlson HK, Wetmore KM, Price MN, Iavarone AT, Deutschbauer AM, Arkin AP, Coates JD.

MBio. 2015 May 12;6(3):e00233-15. doi: 10.1128/mBio.00233-15.


Isotope-targeted glycoproteomics (IsoTaG): a mass-independent platform for intact N- and O-glycopeptide discovery and analysis.

Woo CM, Iavarone AT, Spiciarich DR, Palaniappan KK, Bertozzi CR.

Nat Methods. 2015 Jun;12(6):561-7. doi: 10.1038/nmeth.3366. Epub 2015 Apr 20.


GEMM-I riboswitches from Geobacter sense the bacterial second messenger cyclic AMP-GMP.

Kellenberger CA, Wilson SC, Hickey SF, Gonzalez TL, Su Y, Hallberg ZF, Brewer TF, Iavarone AT, Carlson HK, Hsieh YF, Hammond MC.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5383-8. doi: 10.1073/pnas.1419328112. Epub 2015 Apr 6.


PqqD is a novel peptide chaperone that forms a ternary complex with the radical S-adenosylmethionine protein PqqE in the pyrroloquinoline quinone biosynthetic pathway.

Latham JA, Iavarone AT, Barr I, Juthani PV, Klinman JP.

J Biol Chem. 2015 May 15;290(20):12908-18. doi: 10.1074/jbc.M115.646521. Epub 2015 Mar 27.


(Per)chlorate-reducing bacteria can utilize aerobic and anaerobic pathways of aromatic degradation with (per)chlorate as an electron acceptor.

Carlström CI, Loutey D, Bauer S, Clark IC, Rohde RA, Iavarone AT, Lucas L, Coates JD.

MBio. 2015 Mar 24;6(2). pii: e02287-14. doi: 10.1128/mBio.02287-14.


Mechanisms of direct inhibition of the respiratory sulfate-reduction pathway by (per)chlorate and nitrate.

Carlson HK, Kuehl JV, Hazra AB, Justice NB, Stoeva MK, Sczesnak A, Mullan MR, Iavarone AT, Engelbrektson A, Price MN, Deutschbauer AM, Arkin AP, Coates JD.

ISME J. 2015 Jun;9(6):1295-305. doi: 10.1038/ismej.2014.216. Epub 2014 Nov 18.


The cyclic dinucleotide c-di-AMP is an allosteric regulator of metabolic enzyme function.

Sureka K, Choi PH, Precit M, Delince M, Pensinger DA, Huynh TN, Jurado AR, Goo YA, Sadilek M, Iavarone AT, Sauer JD, Tong L, Woodward JJ.

Cell. 2014 Sep 11;158(6):1389-1401. doi: 10.1016/j.cell.2014.07.046.


Chlorate reduction in Shewanella algae ACDC is a recently acquired metabolism characterized by gene loss, suboptimal regulation and oxidative stress.

Clark IC, Melnyk RA, Iavarone AT, Novichkov PS, Coates JD.

Mol Microbiol. 2014 Oct;94(1):107-25. doi: 10.1111/mmi.12746. Epub 2014 Sep 5.


Chemoenzymatic Fc glycosylation via engineered aldehyde tags.

Smith EL, Giddens JP, Iavarone AT, Godula K, Wang LX, Bertozzi CR.

Bioconjug Chem. 2014 Apr 16;25(4):788-95. doi: 10.1021/bc500061s. Epub 2014 Apr 7.


Nitric oxide-induced conformational changes in soluble guanylate cyclase.

Underbakke ES, Iavarone AT, Chalmers MJ, Pascal BD, Novick S, Griffin PR, Marletta MA.

Structure. 2014 Apr 8;22(4):602-11. doi: 10.1016/j.str.2014.01.008. Epub 2014 Feb 20.


Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.

Jinek M, Jiang F, Taylor DW, Sternberg SH, Kaya E, Ma E, Anders C, Hauer M, Zhou K, Lin S, Kaplan M, Iavarone AT, Charpentier E, Nogales E, Doudna JA.

Science. 2014 Mar 14;343(6176):1247997. doi: 10.1126/science.1247997. Epub 2014 Feb 6.


Antibody enrichment and mass spectrometry of albumin-Cys34 adducts.

Chung MK, Grigoryan H, Iavarone AT, Rappaport SM.

Chem Res Toxicol. 2014 Mar 17;27(3):400-7. doi: 10.1021/tx400337k. Epub 2013 Dec 24.


Site-specific protein transamination using N-methylpyridinium-4-carboxaldehyde.

Witus LS, Netirojjanakul C, Palla KS, Muehl EM, Weng CH, Iavarone AT, Francis MB.

J Am Chem Soc. 2013 Nov 13;135(45):17223-9. doi: 10.1021/ja408868a. Epub 2013 Nov 5.


Free mycolic acid accumulation in the cell wall of the mce1 operon mutant strain of Mycobacterium tuberculosis.

Cantrell SA, Leavell MD, Marjanovic O, Iavarone AT, Leary JA, Riley LW.

J Microbiol. 2013 Oct;51(5):619-26. doi: 10.1007/s12275-013-3092-y. Epub 2013 Sep 14.


Nutritional control of epigenetic processes in yeast and human cells.

Sadhu MJ, Guan Q, Li F, Sales-Lee J, Iavarone AT, Hammond MC, Cande WZ, Rine J.

Genetics. 2013 Nov;195(3):831-44. doi: 10.1534/genetics.113.153981. Epub 2013 Aug 26.

Supplemental Content

Loading ...
Support Center