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Items: 16

1.

Immune Checkpoint Blockade Enhances Shared Neoantigen-Induced T-cell Immunity Directed against Mutated Calreticulin in Myeloproliferative Neoplasms.

Cimen Bozkus C, Roudko V, Finnigan JP, Mascarenhas J, Hoffman R, Iancu-Rubin C, Bhardwaj N.

Cancer Discov. 2019 Sep;9(9):1192-1207. doi: 10.1158/2159-8290.CD-18-1356. Epub 2019 Jul 2.

PMID:
31266769
2.

Novel treatments to tackle myelofibrosis.

Zimran E, Keyzner A, Iancu-Rubin C, Hoffman R, Kremyanskaya M.

Expert Rev Hematol. 2018 Nov;11(11):889-902. doi: 10.1080/17474086.2018.1536538. Epub 2018 Oct 26. Review.

PMID:
30324817
3.

Whirling Platelets Away for Transfusion.

Iancu-Rubin C, Hoffman R, Migliaccio AR.

Cell. 2018 Jul 26;174(3):503-504. doi: 10.1016/j.cell.2018.07.018.

4.

Neonatal expression of RNA-binding protein IGF2BP3 regulates the human fetal-adult megakaryocyte transition.

Elagib KE, Lu CH, Mosoyan G, Khalil S, Zasadzińska E, Foltz DR, Balogh P, Gru AA, Fuchs DA, Rimsza LM, Verhoeyen E, Sansó M, Fisher RP, Iancu-Rubin C, Goldfarb AN.

J Clin Invest. 2017 Jun 1;127(6):2365-2377. doi: 10.1172/JCI88936. Epub 2017 May 8.

5.

Imetelstat, a telomerase inhibitor, differentially affects normal and malignant megakaryopoiesis.

Mosoyan G, Kraus T, Ye F, Eng K, Crispino JD, Hoffman R, Iancu-Rubin C.

Leukemia. 2017 Nov;31(11):2458-2467. doi: 10.1038/leu.2017.78. Epub 2017 Mar 8.

6.

Programmed cell death-1 pathway inhibition in myeloid malignancies: implications for myeloproliferative neoplasms.

Choi DC, Tremblay D, Iancu-Rubin C, Mascarenhas J.

Ann Hematol. 2017 Jun;96(6):919-927. doi: 10.1007/s00277-016-2915-4. Epub 2017 Jan 6. Review.

PMID:
28062906
7.

Preclinical rationale for TGF-β inhibition as a therapeutic target for the treatment of myelofibrosis.

Ceglia I, Dueck AC, Masiello F, Martelli F, He W, Federici G, Petricoin EF 3rd, Zeuner A, Iancu-Rubin C, Weinberg R, Hoffman R, Mascarenhas J, Migliaccio AR.

Exp Hematol. 2016 Dec;44(12):1138-1155.e4. doi: 10.1016/j.exphem.2016.08.007. Epub 2016 Aug 31.

8.

Role of epigenetic reprogramming in hematopoietic stem cell function.

Iancu-Rubin C, Hoffman R.

Curr Opin Hematol. 2015 Jul;22(4):279-85. doi: 10.1097/MOH.0000000000000143. Review.

PMID:
26049747
9.

p27(Kip1) and STMN1: partners again?

Atweh GF, Iancu-Rubin C.

Cell Cycle. 2014;13(20):3163. doi: 10.4161/15384101.2014.966580. No abstract available.

10.

Activation of p53 by the MDM2 inhibitor RG7112 impairs thrombopoiesis.

Iancu-Rubin C, Mosoyan G, Glenn K, Gordon RE, Nichols GL, Hoffman R.

Exp Hematol. 2014 Feb;42(2):137-45.e5. doi: 10.1016/j.exphem.2013.11.012. Epub 2013 Dec 3.

PMID:
24309210
11.

Stromal cell-mediated inhibition of erythropoiesis can be attenuated by Sotatercept (ACE-011), an activin receptor type II ligand trap.

Iancu-Rubin C, Mosoyan G, Wang J, Kraus T, Sung V, Hoffman R.

Exp Hematol. 2013 Feb;41(2):155-166.e17. doi: 10.1016/j.exphem.2012.12.002. Epub 2012 Dec 20.

PMID:
23261964
12.

Panobinostat (LBH589)-induced acetylation of tubulin impairs megakaryocyte maturation and platelet formation.

Iancu-Rubin C, Gajzer D, Mosoyan G, Feller F, Mascarenhas J, Hoffman R.

Exp Hematol. 2012 Jul;40(7):564-74. doi: 10.1016/j.exphem.2012.02.004. Epub 2012 Feb 27.

13.

Down-regulation of stathmin expression is required for megakaryocyte maturation and platelet production.

Iancu-Rubin C, Gajzer D, Tripodi J, Najfeld V, Gordon RE, Hoffman R, Atweh GF.

Blood. 2011 Apr 28;117(17):4580-9. doi: 10.1182/blood-2010-09-305540. Epub 2011 Mar 1.

14.

Design of embedded chimeric peptide nucleic acids that efficiently enter and accurately reactivate gene expression in vivo.

Chen J, Peterson KR, Iancu-Rubin C, Bieker JJ.

Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16846-51. doi: 10.1073/pnas.0912896107. Epub 2010 Sep 13.

15.

Stathmin prevents the transition from a normal to an endomitotic cell cycle during megakaryocytic differentiation.

Iancu-Rubin C, Nasrallah CA, Atweh GF.

Cell Cycle. 2005 Dec;4(12):1774-82. Epub 2005 Dec 13.

PMID:
16258287
16.

p27(Kip1) and stathmin share the stage for the first time.

Iancu-Rubin C, Atweh GF.

Trends Cell Biol. 2005 Jul;15(7):346-8. Review.

PMID:
15951178

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