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Items: 1 to 50 of 99

1.

Immunosuppressive mediators impair pro-inflammatory innate lymphoid cell function in human malignant melanoma.

Ercolano G, Garcia-Garijo A, Salomé B, Gomez-Cadena A, Vanoni G, Mastelic-Gavillet B, Ianaro A, Speiser DE, Romero P, Trabanelli S, Jandus C.

Cancer Immunol Res. 2020 Feb 4. pii: canimm.0504.2019. doi: 10.1158/2326-6066.CIR-19-0504. [Epub ahead of print]

PMID:
32019778
2.

Knockdown of PTGS2 by CRISPR/CAS9 System Designates a New Potential Gene Target for Melanoma Treatment.

Ercolano G, De Cicco P, Rubino V, Terrazzano G, Ruggiero G, Carriero R, Kunderfranco P, Ianaro A.

Front Pharmacol. 2019 Dec 5;10:1456. doi: 10.3389/fphar.2019.01456. eCollection 2019.

3.

Adenosine mediates functional and metabolic suppression of peripheral and tumor-infiltrating CD8+ T cells.

Mastelic-Gavillet B, Navarro Rodrigo B, Décombaz L, Wang H, Ercolano G, Ahmed R, Lozano LE, Ianaro A, Derré L, Valerio M, Tawadros T, Jichlinski P, Nguyen-Ngoc T, Speiser DE, Verdeil G, Gestermann N, Dormond O, Kandalaft L, Coukos G, Jandus C, Ménétrier-Caux C, Caux C, Ho PC, Romero P, Harari A, Vigano S.

J Immunother Cancer. 2019 Oct 10;7(1):257. doi: 10.1186/s40425-019-0719-5.

4.

Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.

De Cicco P, Ercolano G, Rubino V, Terrazzano G, Ruggiero G, Cirino G, Ianaro A.

Br J Pharmacol. 2020 Feb;177(4):884-897. doi: 10.1111/bph.14824. Epub 2019 Nov 27.

PMID:
31392723
5.

Anti-metastatic Properties of Naproxen-HBTA in a Murine Model of Cutaneous Melanoma.

Ercolano G, De Cicco P, Frecentese F, Saccone I, Corvino A, Giordano F, Magli E, Fiorino F, Severino B, Calderone V, Citi V, Cirino G, Ianaro A.

Front Pharmacol. 2019 Feb 8;10:66. doi: 10.3389/fphar.2019.00066. eCollection 2019. Erratum in: Front Pharmacol. 2019 Feb 26;10:213.

6.

New Drugs from the Sea: Pro-Apoptotic Activity of Sponges and Algae Derived Compounds.

Ercolano G, De Cicco P, Ianaro A.

Mar Drugs. 2019 Jan 7;17(1). pii: E31. doi: 10.3390/md17010031. Review.

7.

Indicaxanthin from Opuntia Ficus Indica (L. Mill) impairs melanoma cell proliferation, invasiveness, and tumor progression.

Allegra M, De Cicco P, Ercolano G, Attanzio A, Busà R, Cirino G, Tesoriere L, Livrea MA, Ianaro A.

Phytomedicine. 2018 Nov 15;50:19-24. doi: 10.1016/j.phymed.2018.09.171. Epub 2018 Sep 18.

PMID:
30466978
8.

MicroRNA-143-3p inhibits growth and invasiveness of melanoma cells by targeting cyclooxygenase-2 and inversely correlates with malignant melanoma progression.

Panza E, Ercolano G, De Cicco P, Armogida C, Scognamiglio G, Botti G, Cirino G, Ianaro A.

Biochem Pharmacol. 2018 Oct;156:52-59. doi: 10.1016/j.bcp.2018.08.008. Epub 2018 Aug 9.

PMID:
30098313
9.

Hydrogen Sulfide Reduces Myeloid-Derived Suppressor Cell-Mediated Inflammatory Response in a Model of Helicobacter hepaticus-Induced Colitis.

De Cicco P, Sanders T, Cirino G, Maloy KJ, Ianaro A.

Front Immunol. 2018 Mar 27;9:499. doi: 10.3389/fimmu.2018.00499. eCollection 2018.

10.

Nutraceuticals: opening the debate for a regulatory framework.

Santini A, Cammarata SM, Capone G, Ianaro A, Tenore GC, Pani L, Novellino E.

Br J Clin Pharmacol. 2018 Apr;84(4):659-672. doi: 10.1111/bcp.13496. Epub 2018 Feb 14. Review.

11.

NMR-based phytochemical analysis of Vitis vinifera cv Falanghina leaves. Characterization of a previously undescribed biflavonoid with antiproliferative activity.

Tartaglione L, Gambuti A, De Cicco P, Ercolano G, Ianaro A, Taglialatela-Scafati O, Moio L, Forino M.

Fitoterapia. 2018 Mar;125:13-17. doi: 10.1016/j.fitote.2017.12.009. Epub 2017 Dec 11.

PMID:
29242038
12.

Antiproliferative metabolites from the Northern African endemic plant Daucus virgatus (Apiaceae).

Snene A, Sirignano C, Rigano D, Formisano C, El Mokni R, Ercolano G, Dhaouadi H, Ianaro A, Hammami S, Taglialatela-Scafati O.

Phytochemistry. 2017 Nov;143:194-198. doi: 10.1016/j.phytochem.2017.08.010. Epub 2017 Aug 23.

PMID:
28843162
13.

Gaseous Mediators in Gastrointestinal Mucosal Defense and Injury.

Wallace JL, Ianaro A, de Nucci G.

Dig Dis Sci. 2017 Sep;62(9):2223-2230. doi: 10.1007/s10620-017-4681-0. Epub 2017 Jul 21. Review.

PMID:
28733867
14.

Preclinical evaluation of the urokinase receptor-derived peptide UPARANT as an anti-inflammatory drug.

Boccella S, Panza E, Lista L, Belardo C, Ianaro A, De Rosa M, de Novellis V, Pavone V.

Inflamm Res. 2017 Aug;66(8):701-709. doi: 10.1007/s00011-017-1051-5. Epub 2017 Apr 29.

PMID:
28456844
15.

The Hydrogen Sulfide Releasing Molecule Acetyl Deacylasadisulfide Inhibits Metastatic Melanoma.

De Cicco P, Panza E, Armogida C, Ercolano G, Taglialatela-Scafati O, Shokoohinia Y, Camerlingo R, Pirozzi G, Calderone V, Cirino G, Ianaro A.

Front Pharmacol. 2017 Feb 27;8:65. doi: 10.3389/fphar.2017.00065. eCollection 2017.

16.

COX-2 expression positively correlates with PD-L1 expression in human melanoma cells.

Botti G, Fratangelo F, Cerrone M, Liguori G, Cantile M, Anniciello AM, Scala S, D'Alterio C, Trimarco C, Ianaro A, Cirino G, Caracò C, Colombino M, Palmieri G, Pepe S, Ascierto PA, Sabbatino F, Scognamiglio G.

J Transl Med. 2017 Feb 23;15(1):46. doi: 10.1186/s12967-017-1150-7.

17.

ATB-346, a novel hydrogen sulfide-releasing anti-inflammatory drug, induces apoptosis of human melanoma cells and inhibits melanoma development in vivo.

De Cicco P, Panza E, Ercolano G, Armogida C, Sessa G, Pirozzi G, Cirino G, Wallace JL, Ianaro A.

Pharmacol Res. 2016 Dec;114:67-73. doi: 10.1016/j.phrs.2016.10.019. Epub 2016 Oct 21.

PMID:
27777130
18.

Differential expression of cyclooxygenase-2 in metastatic melanoma affects progression free survival.

Panza E, De Cicco P, Ercolano G, Armogida C, Scognamiglio G, Anniciello AM, Botti G, Cirino G, Ianaro A.

Oncotarget. 2016 Aug 30;7(35):57077-57085. doi: 10.18632/oncotarget.10976.

19.

Hydrogen sulfide-releasing anti-inflammatory drugs for chemoprevention and treatment of cancer.

Ianaro A, Cirino G, Wallace JL.

Pharmacol Res. 2016 Sep;111:652-658. doi: 10.1016/j.phrs.2016.07.041. Epub 2016 Jul 27. Review.

PMID:
27475881
20.

Profound Chemopreventative Effects of a Hydrogen Sulfide-Releasing NSAID in the APCMin/+ Mouse Model of Intestinal Tumorigenesis.

Paul-Clark M, Elsheikh W, Kirkby N, Chan M, Devchand P, Agbor TA, Flannigan KL, Cheadle C, Freydin M, Ianaro A, Mitchell JA, Wallace JL.

PLoS One. 2016 Feb 24;11(2):e0147289. doi: 10.1371/journal.pone.0147289. eCollection 2016.

21.

Correction: Human Cystathionine-β-Synthase Phosphorylation on Serine227 Modulates Hydrogen Sulfide Production in Human Urothelium.

d'Emmanuele di Villa Bianca R, Mitidieri E, Esposito D, Donnarumma E, Russo A, Fusco F, Ianaro A, Mirone V, Cirino G, Russo G, Sorrentino R.

PLoS One. 2015 Oct 15;10(10):e0141027. doi: 10.1371/journal.pone.0141027. eCollection 2015. No abstract available.

22.

Cystathionine β-synthase-derived hydrogen sulfide is involved in human malignant hyperthermia.

Vellecco V, Mancini A, Ianaro A, Calderone V, Attanasio C, Cantalupo A, Andria B, Savoia G, Panza E, Di Martino A, Cirino G, Bucci M.

Clin Sci (Lond). 2016 Jan;130(1):35-44. doi: 10.1042/CS20150521. Epub 2015 Oct 12.

PMID:
26460077
23.

Human Cystathionine-β-Synthase Phosphorylation on Serine227 Modulates Hydrogen Sulfide Production in Human Urothelium.

d'Emmanuele di Villa Bianca R, Mitidieri E, Esposito D, Donnarumma E, Russo A, Fusco F, Ianaro A, Mirone V, Cirino G, Russo G, Sorrentino R.

PLoS One. 2015 Sep 14;10(9):e0136859. doi: 10.1371/journal.pone.0136859. eCollection 2015. Erratum in: PLoS One. 2015;10(10):e0141027. Donnarumm, Erminia [corrected to Donnarumma, Erminia]. Retraction in: PLoS One. 2019 Sep 12;14(9):e0222416.

24.

Gaseous mediators in resolution of inflammation.

Wallace JL, Ianaro A, Flannigan KL, Cirino G.

Semin Immunol. 2015 May;27(3):227-33. doi: 10.1016/j.smim.2015.05.004. Epub 2015 Jun 18. Review.

PMID:
26095908
25.

S1P-induced airway smooth muscle hyperresponsiveness and lung inflammation in vivo: molecular and cellular mechanisms.

Roviezzo F, Sorrentino R, Bertolino A, De Gruttola L, Terlizzi M, Pinto A, Napolitano M, Castello G, D'Agostino B, Ianaro A, Sorrentino R, Cirino G.

Br J Pharmacol. 2015 Apr;172(7):1882-93. doi: 10.1111/bph.13033. Epub 2015 Jan 23.

26.

Role of the cystathionine γ lyase/hydrogen sulfide pathway in human melanoma progression.

Panza E, De Cicco P, Armogida C, Scognamiglio G, Gigantino V, Botti G, Germano D, Napolitano M, Papapetropoulos A, Bucci M, Cirino G, Ianaro A.

Pigment Cell Melanoma Res. 2015 Jan;28(1):61-72. doi: 10.1111/pcmr.12312. Epub 2014 Oct 6.

PMID:
25205294
27.

Crucial role of androgen receptor in vascular H2S biosynthesis induced by testosterone.

Brancaleone V, Vellecco V, Matassa DS, d'Emmanuele di Villa Bianca R, Sorrentino R, Ianaro A, Bucci M, Esposito F, Cirino G.

Br J Pharmacol. 2015 Mar;172(6):1505-15. doi: 10.1111/bph.12740. Epub 2014 Jul 2.

28.

Indicaxanthin from cactus pear fruit exerts anti-inflammatory effects in carrageenin-induced rat pleurisy.

Allegra M, Ianaro A, Tersigni M, Panza E, Tesoriere L, Livrea MA.

J Nutr. 2014 Feb;144(2):185-92. doi: 10.3945/jn.113.183657. Epub 2013 Dec 4.

PMID:
24306215
29.

Involvement of proteinase activated receptor-2 in the vascular response to sphingosine 1-phosphate.

Roviezzo F, De Angelis A, De Gruttola L, Bertolino A, Sullo N, Brancaleone V, Bucci M, De Palma R, Urbanek K, D'Agostino B, Ianaro A, Sorrentino R, Cirino G.

Clin Sci (Lond). 2014 Apr;126(8):545-56. doi: 10.1042/CS20130272.

PMID:
24131465
30.

Perthamide C inhibits eNOS and iNOS expression and has immunomodulating activity in vivo.

Bucci M, Cantalupo A, Vellecco V, Panza E, Monti MC, Zampella A, Ianaro A, Cirino G.

PLoS One. 2013;8(3):e57801. doi: 10.1371/journal.pone.0057801. Epub 2013 Mar 12. Retraction in: PLoS One. 2019 Aug 30;14(8):e0222175.

31.

Nociceptin/orphanin FQ receptor activation decreases the airway hyperresponsiveness induced by allergen in sensitized mice.

Sullo N, Roviezzo F, Matteis M, Ianaro A, Calò G, Guerrini R, De Gruttola L, Spaziano G, Cirino G, Rossi F, D'Agostino B.

Am J Physiol Lung Cell Mol Physiol. 2013 May 15;304(10):L657-64. doi: 10.1152/ajplung.00358.2012. Epub 2013 Mar 15.

32.

Cross-talk between toll-like receptor 4 (TLR4) and proteinase-activated receptor 2 (PAR(2) ) is involved in vascular function.

Bucci M, Vellecco V, Harrington L, Brancaleone V, Roviezzo F, Mattace Raso G, Ianaro A, Lungarella G, De Palma R, Meli R, Cirino G.

Br J Pharmacol. 2013 Jan;168(2):411-20. doi: 10.1111/j.1476-5381.2012.02205.x.

33.

Sinularioside, a triacetylated glycolipid from the Indonesian soft coral Sinularia sp., is an inhibitor of NO release.

Putra MY, Ianaro A, Panza E, Bavestrello G, Cerrano C, Fattorusso E, Taglialatela-Scafati O.

Bioorg Med Chem Lett. 2012 Apr 15;22(8):2723-5. doi: 10.1016/j.bmcl.2012.02.102. Epub 2012 Mar 8.

PMID:
22446094
34.

Tedarenes A and B: structural and stereochemical analysis of two new strained cyclic diarylheptanoids from the marine sponge Tedania ignis.

Costantino V, Fattorusso E, Mangoni A, Perinu C, Teta R, Panza E, Ianaro A.

J Org Chem. 2012 Aug 3;77(15):6377-83. doi: 10.1021/jo300295j. Epub 2012 Mar 29.

PMID:
22443364
35.

Apolipoprotein A-I (ApoA-I) mimetic peptide P2a by restoring cholesterol esterification unmasks ApoA-I anti-inflammatory endogenous activity in vivo.

Bucci M, Cigliano L, Vellecco V, D'Andrea LD, Ziaco B, Rossi A, Sautebin L, Carlucci A, Abrescia P, Pedone C, Ianaro A, Cirino G.

J Pharmacol Exp Ther. 2012 Mar;340(3):716-22. doi: 10.1124/jpet.111.189308. Epub 2011 Dec 13.

PMID:
22171091
36.

Nanocapsules based on linear and Y-shaped 3-miktoarm star-block PEO-PCL copolymers as sustained delivery system for hydrophilic molecules.

Maglio G, Nicodemi F, Conte C, Palumbo R, Tirino P, Panza E, Ianaro A, Ungaro F, Quaglia F.

Biomacromolecules. 2011 Dec 12;12(12):4221-9. doi: 10.1021/bm201036r. Epub 2011 Nov 22.

PMID:
22047492
37.

Lauroside B, a megastigmane glycoside from Laurus nobilis (bay laurel) leaves, induces apoptosis in human melanoma cell lines by inhibiting NF-κB activation.

Panza E, Tersigni M, Iorizzi M, Zollo F, De Marino S, Festa C, Napolitano M, Castello G, Ialenti A, Ianaro A.

J Nat Prod. 2011 Feb 25;74(2):228-33. doi: 10.1021/np100688g. Epub 2010 Dec 28.

PMID:
21188975
38.

The I{kappa}B kinase inhibitor nuclear factor-{kappa}B essential modulator-binding domain peptide for inhibition of injury-induced neointimal formation.

Grassia G, Maddaluno M, Musilli C, De Stefano D, Carnuccio R, Di Lauro MV, Parratt CA, Kennedy S, Di Meglio P, Ianaro A, Maffia P, Parenti A, Ialenti A.

Arterioscler Thromb Vasc Biol. 2010 Dec;30(12):2458-66. doi: 10.1161/ATVBAHA.110.215467. Epub 2010 Oct 7.

PMID:
20930169
39.

Terpioside B, a difucosyl GSL from the marine sponge Terpios sp. is a potent inhibitor of NO release.

Costantino V, Fattorusso E, Mangoni A, Teta R, Panza E, Ianaro A.

Bioorg Med Chem. 2010 Jul 15;18(14):5310-5. doi: 10.1016/j.bmc.2010.05.048. Epub 2010 May 24.

PMID:
20624608
40.

New insight in LPS antagonist.

Ianaro A, Tersigni M, D'Acquisto F.

Mini Rev Med Chem. 2009 Mar;9(3):306-17. Review.

PMID:
19275723
41.

NEMO-binding domain peptide inhibits proliferation of human melanoma cells.

Ianaro A, Tersigni M, Belardo G, Di Martino S, Napolitano M, Palmieri G, Sini M, De Maio A, Ombra M, Gentilcore G, Capone M, Ascierto M, Satriano RA, Farina B, Faraone-Mennella M, Ascierto PA, Ialenti A.

Cancer Lett. 2009 Feb 18;274(2):331-6. doi: 10.1016/j.canlet.2008.09.038. Epub 2008 Nov 11.

PMID:
19004544
42.

Thiazolidinediones are partial agonists for the glucocorticoid receptor.

Matthews L, Berry A, Tersigni M, D'Acquisto F, Ianaro A, Ray D.

Endocrinology. 2009 Jan;150(1):75-86. doi: 10.1210/en.2008-0196. Epub 2008 Sep 18.

43.

Paraliane and pepluane diterpenes as anti-inflammatory agents: first insights in structure-activity relationships.

Barile E, Fattorusso E, Ialenti A, Ianaro A, Lanzotti V.

Bioorg Med Chem Lett. 2007 Aug 1;17(15):4196-200. Epub 2007 May 25.

PMID:
17561395
44.

Neutralization of interleukin-18 inhibits neointimal formation in a rat model of vascular injury.

Maffia P, Grassia G, Di Meglio P, Carnuccio R, Berrino L, Garside P, Ianaro A, Ialenti A.

Circulation. 2006 Aug 1;114(5):430-7. Epub 2006 Jul 24.

PMID:
16864728
45.

From willow bark to peptides: the ever widening spectrum of NF-kappaB inhibitors.

D'Acquisto F, Ianaro A.

Curr Opin Pharmacol. 2006 Aug;6(4):387-92. Epub 2006 Jun 14. Review.

PMID:
16781194
46.

A novel lipid A from Halomonas magadiensis inhibits enteric LPS-induced human monocyte activation.

Ialenti A, Di Meglio P, Grassia G, Maffia P, Di Rosa M, Lanzetta R, Molinaro A, Silipo A, Grant W, Ianaro A.

Eur J Immunol. 2006 Feb;36(2):354-60.

47.

Discovery and biological evaluation of the novel naturally occurring diterpene pepluanone as antiinflammatory agent.

Corea G, Fattorusso E, Lanzotti V, Di Meglio P, Maffia P, Grassia G, Ialenti A, Ianaro A.

J Med Chem. 2005 Nov 3;48(22):7055-62.

PMID:
16250665
48.

New sesquiterpene lactones from Laurus nobilis leaves as inhibitors of nitric oxide production.

De Marino S, Borbone N, Zollo F, Ianaro A, Di Meglio P, Iorizzi M.

Planta Med. 2005 Aug;71(8):706-10.

PMID:
16142632
49.

The IkappaB kinase is a key factor in triggering influenza A virus-induced inflammatory cytokine production in airway epithelial cells.

Bernasconi D, Amici C, La Frazia S, Ianaro A, Santoro MG.

J Biol Chem. 2005 Jun 24;280(25):24127-34. Epub 2005 Apr 18.

50.

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