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Items: 1 to 50 of 185

1.

Expression of PD-L1 and SOX2 during rectal tumourigenesis: Potential mechanisms for immune escape and tumour cell invasion.

Miller TJ, Mccoy MJ, Hemmings C, Iacopetta B, Platell CF.

Oncol Lett. 2018 Nov;16(5):5761-5768. doi: 10.3892/ol.2018.9337. Epub 2018 Aug 21.

2.

Prognostic significance of immune cells in non-small cell lung cancer: meta-analysis.

Soo RA, Chen Z, Yan Teng RS, Tan HL, Iacopetta B, Tai BC, Soong R.

Oncotarget. 2018 May 15;9(37):24801-24820. doi: 10.18632/oncotarget.24835. eCollection 2018 May 15.

3.

Implementation of next generation sequencing technology for somatic mutation detection in routine laboratory practice.

Giardina T, Robinson C, Grieu-Iacopetta F, Millward M, Iacopetta B, Spagnolo D, Amanuel B.

Pathology. 2018 Jun;50(4):389-401. doi: 10.1016/j.pathol.2018.01.005. Epub 2018 May 8.

PMID:
29752127
4.

Tumor PIK3CA Genotype and Prognosis in Early-Stage Breast Cancer: A Pooled Analysis of Individual Patient Data.

Zardavas D, Te Marvelde L, Milne RL, Fumagalli D, Fountzilas G, Kotoula V, Razis E, Papaxoinis G, Joensuu H, Moynahan ME, Hennessy BT, Bieche I, Saal LH, Stal O, Iacopetta B, Jensen JD, O'Toole S, Lopez-Knowles E, Barbaraeschi M, Noguchi S, Azim HA Jr, Lerma E, Bachelot T, Wang Q, Perez-Tenorio G, Can de Velde CJH, Rea DW, Sabine V, Bartlett JMS, Sotiriou C, Michiels S, Loi S.

J Clin Oncol. 2018 Apr 1;36(10):981-990. doi: 10.1200/JCO.2017.74.8301. Epub 2018 Feb 22.

5.

Determinants of variability of five programmed death ligand-1 immunohistochemistry assays in non-small cell lung cancer samples.

Soo RA, Yun Lim JS, Asuncion BR, Fazreen Z, Herrera MC, Mohd Omar MF, Diem Phuong NH, Seet JE, Amanuel B, Iacopetta B, Byrne D, Hendry S, Fox S, Soong R.

Oncotarget. 2018 Jan 2;9(6):6841-6851. doi: 10.18632/oncotarget.23827. eCollection 2018 Jan 23.

6.

Acquired resistance to PI3K/mTOR inhibition is associated with mitochondrial DNA mutation and glycolysis.

Koh KX, Tan GH, Hui Low SH, Mohd Omar MF, Han MJ, Iacopetta B, Soo R, Beloueche-Babari M, Bhattacharya B, Soong R.

Oncotarget. 2017 Nov 24;8(66):110133-110144. doi: 10.18632/oncotarget.22655. eCollection 2017 Dec 15.

7.

The prognostic value of cancer stem-like cell markers SOX2 and CD133 in stage III colon cancer is modified by expression of the immune-related markers FoxP3, PD-L1 and CD3.

Miller TJ, McCoy MJ, Hemmings C, Bulsara MK, Iacopetta B, Platell CF.

Pathology. 2017 Dec;49(7):721-730. doi: 10.1016/j.pathol.2017.08.007. Epub 2017 Nov 6.

PMID:
29102042
8.

Screening for Lynch syndrome in young Saudi colorectal cancer patients using microsatellite instability testing and next generation sequencing.

Alqahtani M, Edwards C, Buzzacott N, Carpenter K, Alsaleh K, Alsheikh A, Abozeed W, Mashhour M, Almousa A, Housawi Y, Al Hawwaj S, Iacopetta B.

Fam Cancer. 2018 Apr;17(2):197-203. doi: 10.1007/s10689-017-0015-9.

PMID:
28643016
9.

Objective analysis of cancer stem cell marker expression using immunohistochemistry.

Miller TJ, McCoy MJ, Hemmings C, Bulsara MK, Iacopetta B, Platell CF.

Pathology. 2017 Jan;49(1):24-29. doi: 10.1016/j.pathol.2016.09.063. Epub 2016 Nov 29.

PMID:
27913042
10.

Screening for Lynch Syndrome in Young Colorectal Cancer Patients from Saudi Arabia Using Microsatellite Instability as the Initial Test.

Alqahtani M, Grieu F, Carrello A, Amanuel B, Mashour M, Alattas R, Alsaleh K, Alsheikh A, Alqahtani S, Iacopetta B.

Asian Pac J Cancer Prev. 2016;17(4):1917-23.

11.

HSP110 T17 simplifies and improves the microsatellite instability testing in patients with colorectal cancer.

Buhard O, Lagrange A, Guilloux A, Colas C, Chouchène M, Wanherdrick K, Coulet F, Guillerm E, Dorard C, Marisa L, Bokhari A, Greene M, El-Murr N, Bodo S, Muleris M, Sourouille I, Svrcek M, Cervera P, Blanché H, Lefevre JH, Parc Y, Lepage C, Chapusot C, Bouvier AM, Gaub MP, Selves J, Garrett K, Iacopetta B, Soong R, Hamelin R, Garrido C, Lascols O, André T, Fléjou JF, Collura A, Duval A.

J Med Genet. 2016 Jun;53(6):377-84. doi: 10.1136/jmedgenet-2015-103518. Epub 2016 Feb 1.

PMID:
26831756
12.

FOXP3+ T regulatory lymphocytes in primary melanoma are associated with BRAF mutation but not with response to BRAF inhibitor.

Leslie C, Bowyer SE, White A, Grieu-Iacopetta F, Trevenen M, Iacopetta B, Amanuel B, Millward M.

Pathology. 2015 Oct;47(6):557-63. doi: 10.1097/PAT.0000000000000314.

PMID:
26308130
13.

Feasibility of low-throughput next generation sequencing for germline DNA screening.

Sapari NS, Elahi E, Wu M, Loh M, Ng HK, Han X, Yap HL, Klemm TP, Pang B, Benoukraf T, Teo YY, Iacopetta B, Lee SC, Soong R.

Clin Chem. 2014 Dec;60(12):1549-57. doi: 10.1373/clinchem.2014.227728. Epub 2014 Oct 22.

14.

KRAS mutation testing of metastatic colorectal cancer in Australia: where are we at?

Scott RJ, Fox SB, Desai J, Grieu F, Amanuel B, Garrett K, Harraway J, Cheetham G, Pattle N, Haddad A, Byron K, Rudzki B, Waring P, Iacopetta B.

Asia Pac J Clin Oncol. 2014 Sep;10(3):261-5. doi: 10.1111/ajco.12201. Epub 2014 May 9.

PMID:
24811330
15.

DNA methylation subgroups and the CpG island methylator phenotype in gastric cancer: a comprehensive profiling approach.

Loh M, Liem N, Vaithilingam A, Lim PL, Sapari NS, Elahi E, Mok ZY, Cheng CL, Yan B, Pang B, Salto-Tellez M, Yong WP, Iacopetta B, Soong R.

BMC Gastroenterol. 2014 Mar 28;14:55. doi: 10.1186/1471-230X-14-55.

16.

Patients with colorectal tumors with microsatellite instability and large deletions in HSP110 T17 have improved response to 5-fluorouracil–based chemotherapy.

Collura A, Lagrange A, Svrcek M, Marisa L, Buhard O, Guilloux A, Wanherdrick K, Dorard C, Taieb A, Saget A, Loh M, Soong R, Zeps N, Platell C, Mews A, Iacopetta B, De Thonel A, Seigneuric R, Marcion G, Chapusot C, Lepage C, Bouvier AM, Gaub MP, Milano G, Selves J, Senet P, Delarue P, Arzouk H, Lacoste C, Coquelle A, Bengrine-Lefèvre L, Tournigand C, Lefèvre JH, Parc Y, Biard DS, Fléjou JF, Garrido C, Duval A.

Gastroenterology. 2014 Feb;146(2):401-11.e1.

PMID:
24512910
17.

Population-based screening for Lynch syndrome in Western Australia.

Schofield L, Grieu F, Amanuel B, Carrello A, Spagnolo D, Kiraly C, Pachter N, Goldblatt J, Platell C, Levitt M, Stewart C, Salama P, Ee H, Raftopoulous S, Katris P, Threlfall T, Edkins E, Wallace M, Iacopetta B.

Int J Cancer. 2014 Sep 1;135(5):1085-91. doi: 10.1002/ijc.28744. Epub 2014 Feb 24.

18.

Phosphatidylinositol-3-kinase pathway aberrations in gastric and colorectal cancer: meta-analysis, co-occurrence and ethnic variation.

Chong ML, Loh M, Thakkar B, Pang B, Iacopetta B, Soong R.

Int J Cancer. 2014 Mar 1;134(5):1232-8. doi: 10.1002/ijc.28444. Epub 2013 Sep 17.

19.

A multisite blinded study for the detection of BRAF mutations in formalin-fixed, paraffin-embedded malignant melanoma.

Richter A, Grieu F, Carrello A, Amanuel B, Namdarian K, Rynska A, Lucas A, Michael V, Bell A, Fox SB, Hewitt CA, Do H, McArthur GA, Wong SQ, Dobrovic A, Iacopetta B.

Sci Rep. 2013;3:1659. doi: 10.1038/srep01659.

20.

Epstein-Barr virus, human papillomavirus and mouse mammary tumour virus as multiple viruses in breast cancer.

Glenn WK, Heng B, Delprado W, Iacopetta B, Whitaker NJ, Lawson JS.

PLoS One. 2012;7(11):e48788. doi: 10.1371/journal.pone.0048788. Epub 2012 Nov 19.

21.

Dietary and supplemental folate and the risk of left- and right-sided colorectal cancer.

Clapin HF, Fritschi L, Iacopetta B, Heyworth JS.

Nutr Cancer. 2012;64(7):937-45. doi: 10.1080/01635581.2012.715718. Epub 2012 Oct 4.

22.

Integrating next-generation sequencing into the diagnostic testing of inherited cancer predisposition.

Ku CS, Cooper DN, Iacopetta B, Roukos DH.

Clin Genet. 2013 Jan;83(1):2-6. doi: 10.1111/cge.12028. Epub 2012 Oct 29.

PMID:
23020236
23.

The topography of DNA methylation in the non-neoplastic colonic mucosa surrounding colorectal cancers.

Subramaniam MM, Loh M, Chan JY, Liem N, Lim PL, Peng YW, Lim XY, Yeoh KG, Iacopetta B, Soong R, Salto-Tellez M.

Mol Carcinog. 2014 Feb;53(2):98-108. doi: 10.1002/mc.21951. Epub 2012 Aug 21.

PMID:
22911899
24.

Can population differences in chemotherapy outcomes be inferred from differences in pharmacogenetic frequencies?

Loh M, Chua D, Yao Y, Soo RA, Garrett K, Zeps N, Platell C, Minamoto T, Kawakami K, Iacopetta B, Soong R.

Pharmacogenomics J. 2013 Oct;13(5):423-9. doi: 10.1038/tpj.2012.26. Epub 2012 Jun 26.

PMID:
22733238
25.

Incidence of BRAF p.Val600Glu and p.Val600Lys mutations in a consecutive series of 183 metastatic melanoma patients from a high incidence region.

Amanuel B, Grieu F, Kular J, Millward M, Iacopetta B.

Pathology. 2012 Jun;44(4):357-9. doi: 10.1097/PAT.0b013e3283532565.

PMID:
22614711
26.

Gene discovery in familial cancer syndromes by exome sequencing: prospects for the elucidation of familial colorectal cancer type X.

Ku CS, Cooper DN, Wu M, Roukos DH, Pawitan Y, Soong R, Iacopetta B.

Mod Pathol. 2012 Aug;25(8):1055-68. doi: 10.1038/modpathol.2012.62. Epub 2012 Apr 20. Review.

27.

Exome versus transcriptome sequencing in identifying coding region variants.

Ku CS, Wu M, Cooper DN, Naidoo N, Pawitan Y, Pang B, Iacopetta B, Soong R.

Expert Rev Mol Diagn. 2012 Apr;12(3):241-51. doi: 10.1586/erm.12.10. Review.

PMID:
22468815
28.

Technological advances in DNA sequence enrichment and sequencing for germline genetic diagnosis.

Ku CS, Wu M, Cooper DN, Naidoo N, Pawitan Y, Pang B, Iacopetta B, Soong R.

Expert Rev Mol Diagn. 2012 Mar;12(2):159-73. doi: 10.1586/erm.11.95. Review.

PMID:
22369376
29.

Villin expression is frequently lost in poorly differentiated colon cancer.

Arango D, Al-Obaidi S, Williams DS, Dopeso H, Mazzolini R, Corner G, Byun DS, Carr AA, Murone C, Tögel L, Zeps N, Aaltonen LA, Iacopetta B, Mariadason JM.

Am J Pathol. 2012 Apr;180(4):1509-21. doi: 10.1016/j.ajpath.2012.01.006. Epub 2012 Feb 18.

30.

FOXP3+ cell density in lymphoid follicles from histologically normal mucosa is a strong prognostic factor in early stage colon cancer.

Salama P, Stewart C, Forrest C, Platell C, Iacopetta B.

Cancer Immunol Immunother. 2012 Aug;61(8):1183-90. doi: 10.1007/s00262-011-1191-3. Epub 2011 Dec 31.

PMID:
22210551
31.

Challenges in the diagnosis and management of Lynch Syndrome in an Indigenous family living in a remote West Australian community.

Schofield L, Goldblatt J, Iacopetta B.

Rural Remote Health. 2011;11(4):1836. Epub 2011 Dec 22.

32.

A state-wide population-based program for detection of lynch syndrome based upon immunohistochemical and molecular testing of colorectal tumours.

Schofield L, Grieu F, Goldblatt J, Amanuel B, Iacopetta B.

Fam Cancer. 2012 Mar;11(1):1-6. doi: 10.1007/s10689-011-9494-2.

PMID:
22120844
33.

Fruit and vegetable consumption and the risk of proximal colon, distal colon, and rectal cancers in a case-control study in Western Australia.

Annema N, Heyworth JS, McNaughton SA, Iacopetta B, Fritschi L.

J Am Diet Assoc. 2011 Oct;111(10):1479-90. doi: 10.1016/j.jada.2011.07.008.

PMID:
21963014
34.

Low expression of Granzyme B in colorectal cancer is associated with signs of early metastastic invasion.

Salama P, Phillips M, Platell C, Iacopetta B.

Histopathology. 2011 Aug;59(2):207-15. doi: 10.1111/j.1365-2559.2011.03915.x.

PMID:
21884199
35.

Sequential expression of putative stem cell markers in gastric carcinogenesis.

Wang T, Ong CW, Shi J, Srivastava S, Yan B, Cheng CL, Yong WP, Chan SL, Yeoh KG, Iacopetta B, Salto-Tellez M.

Br J Cancer. 2011 Aug 23;105(5):658-65. doi: 10.1038/bjc.2011.287. Epub 2011 Aug 9.

36.

Low cytosine triphosphate synthase 2 expression renders resistance to 5-fluorouracil in colorectal cancer.

Tan WL, Bhattacharya B, Loh M, Balasubramanian I, Akram M, Dong D, Wong L, Thakkar B, Salto-Tellez M, Soo RA, Fichtner I, Iacopetta B, Soong R.

Cancer Biol Ther. 2011 Mar 15;11(6):599-608. Epub 2011 Mar 15.

PMID:
21378502
37.

Meat consumption and cooking practices and the risk of colorectal cancer.

Tabatabaei SM, Fritschi L, Knuiman MW, Boyle T, Iacopetta BJ, Platell C, Heyworth JS.

Eur J Clin Nutr. 2011 Jun;65(6):668-75. doi: 10.1038/ejcn.2011.17. Epub 2011 Mar 2.

PMID:
21364608
38.

Microsatellite instability in colorectal cancer.

Iacopetta B, Grieu F, Amanuel B.

Asia Pac J Clin Oncol. 2010 Dec;6(4):260-9. doi: 10.1111/j.1743-7563.2010.01335.x. Epub 2010 Oct 26. Review.

PMID:
21114775
39.

Selected dietary micronutrients and the risk of right- and left-sided colorectal cancers: a case-control study in Western Australia.

van Lee L, Heyworth J, McNaughton S, Iacopetta B, Clayforth C, Fritschi L.

Ann Epidemiol. 2011 Mar;21(3):170-7. doi: 10.1016/j.annepidem.2010.10.005. Epub 2010 Dec 15.

PMID:
21109455
40.

KRAS mutation and microsatellite instability in endometrial adenocarcinomas showing MELF-type myometrial invasion.

Stewart CJ, Amanuel B, Grieu F, Carrello A, Iacopetta B.

J Clin Pathol. 2010 Jul;63(7):604-8. doi: 10.1136/jcp.2009.069500.

PMID:
20591910
41.

Tumour banking as part of routine clinical practice.

Platell C, Zeps N, Joseph D, Spry N, Iacopetta B, Caruso V.

ANZ J Surg. 2010 Apr;80(4):203-4. doi: 10.1111/j.1445-2197.2010.05239.x. No abstract available.

PMID:
20575941
42.

Comprehensive profiling of DNA methylation in colorectal cancer reveals subgroups with distinct clinicopathological and molecular features.

Ang PW, Loh M, Liem N, Lim PL, Grieu F, Vaithilingam A, Platell C, Yong WP, Iacopetta B, Soong R.

BMC Cancer. 2010 May 21;10:227. doi: 10.1186/1471-2407-10-227.

43.

MicroRNA-130b regulates the tumour suppressor RUNX3 in gastric cancer.

Lai KW, Koh KX, Loh M, Tada K, Subramaniam MM, Lim XY, Vaithilingam A, Salto-Tellez M, Iacopetta B, Ito Y, Soong R; Singapore Gastric Cancer Consortium.

Eur J Cancer. 2010 May;46(8):1456-63. doi: 10.1016/j.ejca.2010.01.036. Epub 2010 Feb 20.

PMID:
20176475
44.

CD133 expression predicts for non-response to chemotherapy in colorectal cancer.

Ong CW, Kim LG, Kong HH, Low LY, Iacopetta B, Soong R, Salto-Tellez M.

Mod Pathol. 2010 Mar;23(3):450-7. doi: 10.1038/modpathol.2009.181. Epub 2010 Jan 15.

45.

Genetic factors associated with intestinal metaplasia in a high risk Singapore-Chinese population: a cohort study.

Zhu F, Loh M, Hill J, Lee S, Koh KX, Lai KW, Salto-Tellez M, Iacopetta B, Yeoh KG, Soong R; Singapore Gastric Cancer Consortium.

BMC Gastroenterol. 2009 Oct 13;9:76. doi: 10.1186/1471-230X-9-76.

46.

A multicenter blinded study to evaluate KRAS mutation testing methodologies in the clinical setting.

Whitehall V, Tran K, Umapathy A, Grieu F, Hewitt C, Evans TJ, Ismail T, Li WQ, Collins P, Ravetto P, Leggett B, Salto-Tellez M, Soong R, Fox S, Scott RJ, Dobrovic A, Iacopetta B.

J Mol Diagn. 2009 Nov;11(6):543-52. doi: 10.2353/jmoldx.2009.090057. Epub 2009 Oct 8.

47.

Molecular markers of response and toxicity to FOLFOX chemotherapy in metastatic colorectal cancer.

Chua W, Goldstein D, Lee CK, Dhillon H, Michael M, Mitchell P, Clarke SJ, Iacopetta B.

Br J Cancer. 2009 Sep 15;101(6):998-1004. doi: 10.1038/sj.bjc.6605239. Epub 2009 Aug 11.

48.

Matrix metalloproteinase-2 gene variants and abdominal aortic aneurysm.

Smallwood L, Warrington N, Allcock R, van Bockxmeer F, Palmer LJ, Iacopetta B, Golledge J, Norman PE.

Eur J Vasc Endovasc Surg. 2009 Aug;38(2):169-71. doi: 10.1016/j.ejvs.2009.04.019. Epub 2009 Jun 10.

49.

Meta-analysis of genetic polymorphisms and gastric cancer risk: variability in associations according to race.

Loh M, Koh KX, Yeo BH, Song CM, Chia KS, Zhu F, Yeoh KG, Hill J, Iacopetta B, Soong R.

Eur J Cancer. 2009 Sep;45(14):2562-8. doi: 10.1016/j.ejca.2009.03.017. Epub 2009 Apr 15.

PMID:
19375306
50.

The MTHFR C677T and DeltaDNMT3B C-149T polymorphisms confer different risks for right- and left-sided colorectal cancer.

Iacopetta B, Heyworth J, Girschik J, Grieu F, Clayforth C, Fritschi L.

Int J Cancer. 2009 Jul 1;125(1):84-90. doi: 10.1002/ijc.24324.

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