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Items: 1 to 50 of 85


Defining a microRNA-mRNA interaction map for calcineurin inhibitor induced nephrotoxicity.

Benway CJ, Iacomini J.

Am J Transplant. 2018 Apr;18(4):796-809. doi: 10.1111/ajt.14503. Epub 2017 Oct 30.


Impact of environmental factors on alloimmunity and transplant fate.

Riella LV, Bagley J, Iacomini J, Alegre ML.

J Clin Invest. 2017 Jun 30;127(7):2482-2491. doi: 10.1172/JCI90596. Epub 2017 May 8. Review.


Impact of hyperlipidemia on alloimmunity.

Bagley J, Yuan J, Iacomini J.

Curr Opin Organ Transplant. 2017 Feb;22(1):14-21. doi: 10.1097/MOT.0000000000000381. Review.


Hyperlipidemia Alters Regulatory T Cell Function and Promotes Resistance to Tolerance Induction Through Costimulatory Molecule Blockade.

Bagley J, Yuan J, Chandrakar A, Iacomini J.

Am J Transplant. 2015 Sep;15(9):2324-35. doi: 10.1111/ajt.13351. Epub 2015 Jun 16.


Hyperlipidemia Promotes Anti-Donor Th17 Responses That Accelerate Allograft Rejection.

Yuan J, Bagley J, Iacomini J.

Am J Transplant. 2015 Sep;15(9):2336-45. doi: 10.1111/ajt.13350. Epub 2015 Jun 16.


Retargeting pre-existing human antibodies to a bacterial pathogen with an alpha-Gal conjugated aptamer.

Kristian SA, Hwang JH, Hall B, Leire E, Iacomini J, Old R, Galili U, Roberts C, Mullis KB, Westby M, Nizet V.

J Mol Med (Berl). 2015 Jun;93(6):619-31. doi: 10.1007/s00109-015-1280-4. Epub 2015 May 5.


MicroRNA-494 promotes cyclosporine-induced nephrotoxicity and epithelial to mesenchymal transition by inhibiting PTEN.

Yuan J, Benway CJ, Bagley J, Iacomini J.

Am J Transplant. 2015 Jun;15(6):1682-91. doi: 10.1111/ajt.13161. Epub 2015 Apr 6.


Independent effects of sham laparotomy and anesthesia on hepatic microRNA expression in rats.

Werner W, Sallmon H, Leder A, Lippert S, Reutzel-Selke A, Morgül MH, Jonas S, Dame C, Neuhaus P, Iacomini J, Tullius SG, Sauer IM, Raschzok N.

BMC Res Notes. 2014 Oct 8;7:702. doi: 10.1186/1756-0500-7-702.


The site of allergen expression in hematopoietic cells determines the degree and quality of tolerance induced through molecular chimerism.

Baranyi U, Gattringer M, Farkas AM, Hock K, Pilat N, Iacomini J, Valenta R, Wekerle T.

Eur J Immunol. 2013 Sep;43(9):2451-60. doi: 10.1002/eji.201243277. Epub 2013 Jul 15.


Engraftment of retrovirally transduced Bet v 1-GFP expressing bone marrow cells leads to allergen-specific tolerance.

Gattringer M, Baranyi U, Pilat N, Hock K, Klaus C, Buchberger E, Ramsey H, Iacomini J, Valenta R, Wekerle T.

Immunobiology. 2013 Sep;218(9):1139-46. doi: 10.1016/j.imbio.2013.03.007. Epub 2013 Mar 30.


Tolerance to MHC class II disparate allografts through genetic modification of bone marrow.

Jindra PT, Tripathi S, Tian C, Iacomini J, Bagley J.

Gene Ther. 2013 May;20(5):478-86. doi: 10.1038/gt.2012.57. Epub 2012 Jul 26.


Persistent molecular microchimerism induces long-term tolerance towards a clinically relevant respiratory allergen.

Baranyi U, Pilat N, Gattringer M, Linhart B, Klaus C, Schwaiger E, Iacomini J, Valenta R, Wekerle T.

Clin Exp Allergy. 2012 Aug;42(8):1282-92. doi: 10.1111/j.1365-2222.2012.04049.x.


Critical role of proinflammatory cytokine IL-6 in allograft rejection and tolerance.

Zhao X, Boenisch O, Yeung M, Mfarrej B, Yang S, Turka LA, Sayegh MH, Iacomini J, Yuan X.

Am J Transplant. 2012 Jan;12(1):90-101. doi: 10.1111/j.1600-6143.2011.03770.x. Epub 2011 Oct 12.


MicroRNA expression data reveals a signature of kidney damage following ischemia reperfusion injury.

Shapiro MD, Bagley J, Latz J, Godwin JG, Ge X, Tullius SG, Iacomini J.

PLoS One. 2011;6(8):e23011. doi: 10.1371/journal.pone.0023011. Epub 2011 Aug 15.


A novel clinically relevant approach to tip the balance toward regulation in stringent transplant model.

D'Addio F, Yuan X, Habicht A, Williams J, Ruzek M, Iacomini J, Turka LA, Sayegh MH, Najafian N, Ansari MJ.

Transplantation. 2010 Aug 15;90(3):260-9.


Identification of a microRNA signature of renal ischemia reperfusion injury.

Godwin JG, Ge X, Stephan K, Jurisch A, Tullius SG, Iacomini J.

Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14339-44. doi: 10.1073/pnas.0912701107. Epub 2010 Jul 22.


Costimulation-dependent expression of microRNA-214 increases the ability of T cells to proliferate by targeting Pten.

Jindra PT, Bagley J, Godwin JG, Iacomini J.

J Immunol. 2010 Jul 15;185(2):990-7. doi: 10.4049/jimmunol.1000793. Epub 2010 Jun 14.


Induction of transplantation tolerance to fully mismatched cardiac allografts by T cell mediated delivery of alloantigen.

Tian C, Yuan X, Jindra PT, Bagley J, Sayegh MH, Iacomini J.

Clin Immunol. 2010 Aug;136(2):174-87. doi: 10.1016/j.clim.2010.04.012. Epub 2010 May 8.


Understanding how Tregs are regulated: therapeutic implications.

Yuan X, Sayegh MH, Iacomini J.

Transplantation. 2009 Nov 27;88(10):1159-60. doi: 10.1097/TP.0b013e3181bc236f. No abstract available.


Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells.

Yuan X, Ansari MJ, D'Addio F, Paez-Cortez J, Schmitt I, Donnarumma M, Boenisch O, Zhao X, Popoola J, Clarkson MR, Yagita H, Akiba H, Freeman GJ, Iacomini J, Turka LA, Glimcher LH, Sayegh MH.

Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10734-9. doi: 10.1073/pnas.0812538106. Epub 2009 Jun 15.


Gene therapy in type 1 diabetes.

Bagley J, Paez-Cortez J, Tian C, Iacomini J.

Crit Rev Immunol. 2008;28(4):301-24. Review.


A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy.

Yuan X, Paez-Cortez J, Schmitt-Knosalla I, D'Addio F, Mfarrej B, Donnarumma M, Habicht A, Clarkson MR, Iacomini J, Glimcher LH, Sayegh MH, Ansari MJ.

J Exp Med. 2008 Dec 22;205(13):3133-44. doi: 10.1084/jem.20081937. Epub 2008 Dec 1.


Prevention of type 1 diabetes in NOD mice by genetic engineering of hematopoietic stem cells.

Bagley J, Tian C, Iacomini J.

Methods Mol Biol. 2008;433:277-85. doi: 10.1007/978-1-59745-237-3_17.


Liver sinusoidal endothelial cells as possible vehicles for gene therapy: a comparison between plasmid-based and lentiviral gene transfer techniques.

Paez-Cortez J, Montano R, Iacomini J, Cardier J.

Endothelium. 2008 Jul-Aug;15(4):165-73. doi: 10.1080/10623320802174464.


Tolerization of a type I allergic immune response through transplantation of genetically modified hematopoietic stem cells.

Baranyi U, Linhart B, Pilat N, Gattringer M, Bagley J, Muehlbacher F, Iacomini J, Valenta R, Wekerle T.

J Immunol. 2008 Jun 15;180(12):8168-75.


Ig knock-in mice producing anti-carbohydrate antibodies: breakthrough of B cells producing low affinity anti-self antibodies.

Benatuil L, Kaye J, Cretin N, Godwin JG, Cariappa A, Pillai S, Iacomini J.

J Immunol. 2008 Mar 15;180(6):3839-48.


Induction of transplantation tolerance by combining non-myeloablative conditioning with delivery of alloantigen by T cells.

Tian C, Yuan X, Bagley J, Blazar BR, Sayegh MH, Iacomini J.

Clin Immunol. 2008 May;127(2):130-7. doi: 10.1016/j.clim.2008.01.005. Epub 2008 Feb 15.


Induction of robust diabetes resistance and prevention of recurrent type 1 diabetes following islet transplantation by gene therapy.

Tian C, Ansari MJ, Paez-Cortez J, Bagley J, Godwin J, Donnarumma M, Sayegh MH, Iacomini J.

J Immunol. 2007 Nov 15;179(10):6762-9.


New approaches to the prevention of organ allograft rejection and tolerance induction.

Bagley J, Tian C, Iacomini J.

Transplantation. 2007 Jul 15;84(1 Suppl):S38-41.


Long-term survival of transplanted allogeneic cells engineered to express a T cell chemorepellent.

Papeta N, Chen T, Vianello F, Gererty L, Malik A, Mok YT, Tharp WG, Bagley J, Zhao G, Stevceva L, Yoon V, Sykes M, Sachs D, Iacomini J, Poznansky MC.

Transplantation. 2007 Jan 27;83(2):174-83.


High efficiency and long-term foreign gene expression in cultured liver sinusoidal endothelial cells by retroviral transduction.

Paez J, Montaño R, Benatuil L, Iacomini J, Cardier JE.

Endothelium. 2006 Jul-Aug;13(4):279-85.


Induction of alloreactive CD4 T cell tolerance in molecular chimeras: a possible role for regulatory T cells.

Forman D, Kang ES, Tian C, Paez-Cortez J, Iacomini J.

J Immunol. 2006 Mar 15;176(6):3410-6.


Monitoring tolerance induction.

Iacomini J.

Pediatr Transplant. 2006 Feb;10(1):5-6. No abstract available.


Measuring T cell alloreactivity to predict kidney transplant outcomes: are we there yet?

Iacomini J, Sayegh MH.

J Am Soc Nephrol. 2006 Feb;17(2):328-30. Epub 2005 Dec 28. No abstract available.


The influence of natural antibody specificity on antigen immunogenicity.

Benatuil L, Kaye J, Rich RF, Fishman JA, Green WR, Iacomini J.

Eur J Immunol. 2005 Sep;35(9):2638-47.


Oocyte generation in adult mammalian ovaries by putative germ cells in bone marrow and peripheral blood.

Johnson J, Bagley J, Skaznik-Wikiel M, Lee HJ, Adams GB, Niikura Y, Tschudy KS, Tilly JC, Cortes ML, Forkert R, Spitzer T, Iacomini J, Scadden DT, Tilly JL.

Cell. 2005 Jul 29;122(2):303-15.


Preventing autoimmune diabetes through gene therapy.

Tian C, Bagley J, Iacomini J.

Discov Med. 2005 Apr;5(26):186-90.


Induction of central tolerance by mature T cells.

Tian C, Bagley J, Forman D, Iacomini J.

J Immunol. 2004 Dec 15;173(12):7217-22.


Prevention of type 1 diabetes by gene therapy.

Tian C, Bagley J, Cretin N, Seth N, Wucherpfennig KW, Iacomini J.

J Clin Invest. 2004 Oct;114(7):969-78.


Bone marrow transplantation restores immune system function and prevents lymphoma in Atm-deficient mice.

Bagley J, Cortes ML, Breakefield XO, Iacomini J.

Blood. 2004 Jul 15;104(2):572-8. Epub 2004 Mar 25.


The role of complement receptors in production of antibodies specific for Galalpha1,3Gal.

Kaye J, Bagley J, Malkowski D, Iacomini J.

Transplantation. 2004 Jan 27;77(2):314-6.


Induction of T cell tolerance to a protein expressed in the cytoplasm through retroviral-mediated gene transfer.

Tian C, Bagley J, Kaye J, Iacomini J.

J Gene Med. 2003 May;5(5):359-65.


Gene therapy progress and prospects: gene therapy in organ transplantation.

Bagley J, Iacomini J.

Gene Ther. 2003 Apr;10(8):605-11. Review.


T cells mediate resistance to genetically modified bone marrow in lethally irradiated recipients.

Bagley J, Tian C, Sachs DH, Iacomini J.

Transplantation. 2002 Nov 27;74(10):1454-60.


Rejection of alphaGAL mismatched skin grafts: a model of acute vascular rejection?

Iacomini J.

Transplantation. 2002 Sep 15;74(5):599-600. No abstract available.


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