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Items: 1 to 50 of 75

1.

Epigenetic upregulation and functional role of the mitochondrial aspartate/glutamate carrier isoform 1 in hepatocellular carcinoma.

Infantino V, Dituri F, Convertini P, Santarsiero A, Palmieri F, Todisco S, Mancarella S, Giannelli G, Iacobazzi V.

Biochim Biophys Acta Mol Basis Dis. 2019 Jan;1865(1):38-47. doi: 10.1016/j.bbadis.2018.10.018. Epub 2018 Oct 12.

PMID:
30321589
2.

FOXD3 acts as a repressor of the mitochondrial S-adenosylmethionine carrier (SLC25A26) gene expression in cancer cells.

Cianciulli A, Menga A, Ferdinando P, Iacobazzi V.

Biochimie. 2018 Nov;154:25-34. doi: 10.1016/j.biochi.2018.07.025. Epub 2018 Aug 2.

PMID:
30076902
3.

Metabolic routes in inflammation: the citrate pathway and its potential as therapeutic target.

Infantino V, Pierri CL, Iacobazzi V.

Curr Med Chem. 2018 May 10. doi: 10.2174/0929867325666180510124558. [Epub ahead of print]

PMID:
29745322
4.

SLC25A26 overexpression impairs cell function via mtDNA hypermethylation and rewiring of methyl metabolism.

Menga A, Palmieri EM, Cianciulli A, Infantino V, Mazzone M, Scilimati A, Palmieri F, Castegna A, Iacobazzi V.

FEBS J. 2017 Mar;284(6):967-984. doi: 10.1111/febs.14028. Epub 2017 Feb 21.

5.

New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity.

Piemontese L, Cerchia C, Laghezza A, Ziccardi P, Sblano S, Tortorella P, Iacobazzi V, Infantino V, Convertini P, Dal Piaz F, Lupo A, Colantuoni V, Lavecchia A, Loiodice F.

Eur J Med Chem. 2017 Feb 15;127:379-397. doi: 10.1016/j.ejmech.2016.12.047. Epub 2016 Dec 24.

PMID:
28076827
6.

The contribution of the citrate pathway to oxidative stress in Down syndrome.

Convertini P, Menga A, Andria G, Scala I, Santarsiero A, Castiglione Morelli MA, Iacobazzi V, Infantino V.

Immunology. 2016 Dec;149(4):423-431. doi: 10.1111/imm.12659. Epub 2016 Oct 3.

7.

Mitochondrial carriers in inflammation induced by bacterial endotoxin and cytokines.

Iacobazzi V, Infantino V, Castegna A, Menga A, Palmieri EM, Convertini P, Palmieri F.

Biol Chem. 2017 Mar;398(3):303-317. doi: 10.1515/hsz-2016-0260.

PMID:
27727142
8.

The mitochondrial side of epigenetics.

Castegna A, Iacobazzi V, Infantino V.

Physiol Genomics. 2015 Aug;47(8):299-307. doi: 10.1152/physiolgenomics.00096.2014. Epub 2015 Jun 2. Review.

PMID:
26038395
9.

Permethylated Anigopreissin A inhibits human hepatoma cell proliferation by mitochondria-induced apoptosis.

Convertini P, Tramutola F, Iacobazzi V, Lupattelli P, Chiummiento L, Infantino V.

Chem Biol Interact. 2015 Jul 25;237:1-8. doi: 10.1016/j.cbi.2015.05.005. Epub 2015 May 14.

PMID:
25980588
10.

Acetylation of human mitochondrial citrate carrier modulates mitochondrial citrate/malate exchange activity to sustain NADPH production during macrophage activation.

Palmieri EM, Spera I, Menga A, Infantino V, Porcelli V, Iacobazzi V, Pierri CL, Hooper DC, Palmieri F, Castegna A.

Biochim Biophys Acta. 2015 Aug;1847(8):729-38. doi: 10.1016/j.bbabio.2015.04.009. Epub 2015 Apr 24.

11.

On the metabolically active form of metaglidasen: improved synthesis and investigation of its peculiar activity on peroxisome proliferator-activated receptors and skeletal muscles.

Laghezza A, Montanari R, Lavecchia A, Piemontese L, Pochetti G, Iacobazzi V, Infantino V, Capelli D, De Bellis M, Liantonio A, Pierno S, Tortorella P, Conte Camerino D, Loiodice F.

ChemMedChem. 2015 Mar;10(3):555-65. doi: 10.1002/cmdc.201402462. Epub 2015 Jan 29.

PMID:
25641779
12.

The mitochondrial aspartate/glutamate carrier isoform 1 gene expression is regulated by CREB in neuronal cells.

Menga A, Iacobazzi V, Infantino V, Avantaggiati ML, Palmieri F.

Int J Biochem Cell Biol. 2015 Mar;60:157-66. doi: 10.1016/j.biocel.2015.01.004. Epub 2015 Jan 14.

13.

Glutamine synthetase desensitizes differentiated adipocytes to proinflammatory stimuli by raising intracellular glutamine levels.

Palmieri EM, Spera I, Menga A, Infantino V, Iacobazzi V, Castegna A.

FEBS Lett. 2014 Dec 20;588(24):4807-14. doi: 10.1016/j.febslet.2014.11.015. Epub 2014 Nov 20.

14.

The human SLC25A33 and SLC25A36 genes of solute carrier family 25 encode two mitochondrial pyrimidine nucleotide transporters.

Di Noia MA, Todisco S, Cirigliano A, Rinaldi T, Agrimi G, Iacobazzi V, Palmieri F.

J Biol Chem. 2014 Nov 28;289(48):33137-48. doi: 10.1074/jbc.M114.610808. Epub 2014 Oct 15.

15.

Hyperhomocysteinemia: related genetic diseases and congenital defects, abnormal DNA methylation and newborn screening issues.

Iacobazzi V, Infantino V, Castegna A, Andria G.

Mol Genet Metab. 2014 Sep-Oct;113(1-2):27-33. doi: 10.1016/j.ymgme.2014.07.016. Epub 2014 Jul 21. Review.

PMID:
25087163
16.

A key role of the mitochondrial citrate carrier (SLC25A1) in TNFα- and IFNγ-triggered inflammation.

Infantino V, Iacobazzi V, Menga A, Avantaggiati ML, Palmieri F.

Biochim Biophys Acta. 2014 Nov;1839(11):1217-1225. doi: 10.1016/j.bbagrm.2014.07.013. Epub 2014 Jul 27.

17.

SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker.

Kolukula VK, Sahu G, Wellstein A, Rodriguez OC, Preet A, Iacobazzi V, D'Orazi G, Albanese C, Palmieri F, Avantaggiati ML.

Oncotarget. 2014 Mar 15;5(5):1212-25.

18.

Citrate--new functions for an old metabolite.

Iacobazzi V, Infantino V.

Biol Chem. 2014 Apr;395(4):387-99. doi: 10.1515/hsz-2013-0271. Review.

PMID:
24445237
19.

ATP-citrate lyase is essential for macrophage inflammatory response.

Infantino V, Iacobazzi V, Palmieri F, Menga A.

Biochem Biophys Res Commun. 2013 Oct 11;440(1):105-11. doi: 10.1016/j.bbrc.2013.09.037. Epub 2013 Sep 17.

PMID:
24051091
20.

MEF2C exon α: role in gene activation and differentiation.

Infantino V, Convertini P, Menga A, Iacobazzi V.

Gene. 2013 Dec 1;531(2):355-62. doi: 10.1016/j.gene.2013.08.044. Epub 2013 Sep 2.

PMID:
24008018
21.

Mitochondrial DNA methylation as a next-generation biomarker and diagnostic tool.

Iacobazzi V, Castegna A, Infantino V, Andria G.

Mol Genet Metab. 2013 Sep-Oct;110(1-2):25-34. doi: 10.1016/j.ymgme.2013.07.012. Epub 2013 Jul 19. Review.

PMID:
23920043
22.

Mechanisms of divergent effects of activated peroxisome proliferator-activated receptor-γ on mitochondrial citrate carrier expression in 3T3-L1 fibroblasts and mature adipocytes.

Bonofiglio D, Santoro A, Martello E, Vizza D, Rovito D, Cappello AR, Barone I, Giordano C, Panza S, Catalano S, Iacobazzi V, Dolce V, Andò S.

Biochim Biophys Acta. 2013 Jun;1831(6):1027-36. doi: 10.1016/j.bbalip.2013.01.014. Epub 2013 Jan 28.

PMID:
23370576
23.
24.

New 2-(aryloxy)-3-phenylpropanoic acids as peroxisome proliferator-activated receptor α/γ dual agonists able to upregulate mitochondrial carnitine shuttle system gene expression.

Laghezza A, Pochetti G, Lavecchia A, Fracchiolla G, Faliti S, Piemontese L, Di Giovanni C, Iacobazzi V, Infantino V, Montanari R, Capelli D, Tortorella P, Loiodice F.

J Med Chem. 2013 Jan 10;56(1):60-72. doi: 10.1021/jm301018z. Epub 2012 Dec 18.

PMID:
23171045
25.

The mitochondrial oxoglutarate carrier: from identification to mechanism.

Monné M, Miniero DV, Iacobazzi V, Bisaccia F, Fiermonte G.

J Bioenerg Biomembr. 2013 Feb;45(1-2):1-13. doi: 10.1007/s10863-012-9475-7. Review. Erratum in: J Bioenerg Biomembr. 2013 Feb;45(1-2):175. Iacobazzi, Vito [added].

PMID:
23054077
26.

Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier.

Menga A, Infantino V, Iacobazzi F, Convertini P, Palmieri F, Iacobazzi V.

Eur Neuropsychopharmacol. 2013 Aug;23(8):978-87. doi: 10.1016/j.euroneuro.2012.08.015. Epub 2012 Sep 7.

PMID:
22959654
27.

The mitochondrial carnitine/acylcarnitine carrier: function, structure and physiopathology.

Indiveri C, Iacobazzi V, Tonazzi A, Giangregorio N, Infantino V, Convertini P, Console L, Palmieri F.

Mol Aspects Med. 2011 Aug;32(4-6):223-33. doi: 10.1016/j.mam.2011.10.008. Epub 2011 Oct 15. Review.

PMID:
22020112
28.

Identification of a novel Sp1 splice variant as a strong transcriptional activator.

Infantino V, Convertini P, Iacobazzi F, Pisano I, Scarcia P, Iacobazzi V.

Biochem Biophys Res Commun. 2011 Aug 19;412(1):86-91. doi: 10.1016/j.bbrc.2011.07.047. Epub 2011 Jul 21.

PMID:
21798247
29.

The mitochondrial citrate carrier: a new player in inflammation.

Infantino V, Convertini P, Cucci L, Panaro MA, Di Noia MA, Calvello R, Palmieri F, Iacobazzi V.

Biochem J. 2011 Sep 15;438(3):433-6. doi: 10.1042/BJ20111275.

PMID:
21787310
30.

Impairment of methyl cycle affects mitochondrial methyl availability and glutathione level in Down's syndrome.

Infantino V, Castegna A, Iacobazzi F, Spera I, Scala I, Andria G, Iacobazzi V.

Mol Genet Metab. 2011 Mar;102(3):378-82. doi: 10.1016/j.ymgme.2010.11.166. Epub 2010 Dec 9.

PMID:
21195648
31.

Role of FOXA and Sp1 in mitochondrial acylcarnitine carrier gene expression in different cell lines.

Convertini P, Infantino V, Bisaccia F, Palmieri F, Iacobazzi V.

Biochem Biophys Res Commun. 2011 Jan 7;404(1):376-81. doi: 10.1016/j.bbrc.2010.11.126. Epub 2010 Dec 3.

PMID:
21130740
32.

Statins, fibrates and retinoic acid upregulate mitochondrial acylcarnitine carrier gene expression.

Iacobazzi V, Convertini P, Infantino V, Scarcia P, Todisco S, Palmieri F.

Biochem Biophys Res Commun. 2009 Oct 30;388(4):643-7. doi: 10.1016/j.bbrc.2009.08.008. Epub 2009 Aug 6.

PMID:
19665003
33.

Transcription of the mitochondrial citrate carrier gene: identification of a silencer and its binding protein ZNF224.

Iacobazzi V, Infantino V, Convertini P, Vozza A, Agrimi G, Palmieri F.

Biochem Biophys Res Commun. 2009 Aug 14;386(1):186-91. doi: 10.1016/j.bbrc.2009.06.003. Epub 2009 Jun 6.

PMID:
19505435
34.

Role of FOXA in mitochondrial citrate carrier gene expression and insulin secretion.

Iacobazzi V, Infantino V, Bisaccia F, Castegna A, Palmieri F.

Biochem Biophys Res Commun. 2009 Jul 24;385(2):220-4. doi: 10.1016/j.bbrc.2009.05.030. Epub 2009 May 13.

PMID:
19445897
35.

Epigenetic mechanisms and Sp1 regulate mitochondrial citrate carrier gene expression.

Iacobazzi V, Infantino V, Palmieri F.

Biochem Biophys Res Commun. 2008 Nov 7;376(1):15-20. doi: 10.1016/j.bbrc.2008.08.015. Epub 2008 Aug 13.

PMID:
18706393
36.

Functional characterization of residues within the carnitine/acylcarnitine translocase RX2PANAAXF distinct motif.

De Lucas JR, Indiveri C, Tonazzi A, Perez P, Giangregorio N, Iacobazzi V, Palmieri F.

Mol Membr Biol. 2008 Feb;25(2):152-63. doi: 10.1080/09687680701697476.

PMID:
18307102
37.

Identification of a New Splice Variant of the Human ABCC6 Transporter.

Armentano MF, Ostuni A, Infantino V, Iacobazzi V, Castiglione Morelli MA, Bisaccia F.

Biochem Res Int. 2008;2008:912478. doi: 10.1155/2008/912478. Epub 2008 Oct 16.

38.

Transcription of the mitochondrial citrate carrier gene: role of SREBP-1, upregulation by insulin and downregulation by PUFA.

Infantino V, Iacobazzi V, De Santis F, Mastrapasqua M, Palmieri F.

Biochem Biophys Res Commun. 2007 Apr 27;356(1):249-54. Epub 2007 Feb 28.

PMID:
17350599
39.

Identification of mitochondrial carriers in Saccharomyces cerevisiae by transport assay of reconstituted recombinant proteins.

Palmieri F, Agrimi G, Blanco E, Castegna A, Di Noia MA, Iacobazzi V, Lasorsa FM, Marobbio CM, Palmieri L, Scarcia P, Todisco S, Vozza A, Walker J.

Biochim Biophys Acta. 2006 Sep-Oct;1757(9-10):1249-62. Epub 2006 May 23. Review.

40.
41.

Molecular and functional analysis of SLC25A20 mutations causing carnitine-acylcarnitine translocase deficiency.

Iacobazzi V, Invernizzi F, Baratta S, Pons R, Chung W, Garavaglia B, Dionisi-Vici C, Ribes A, Parini R, Huertas MD, Roldan S, Lauria G, Palmieri F, Taroni F.

Hum Mutat. 2004 Oct;24(4):312-20.

PMID:
15365988
42.

The structure of Rigidoporus lignosus Laccase containing a full complement of copper ions, reveals an asymmetrical arrangement for the T3 copper pair.

Garavaglia S, Cambria MT, Miglio M, Ragusa S, Iacobazzi V, Palmieri F, D'Ambrosio C, Scaloni A, Rizzi M.

J Mol Biol. 2004 Oct 1;342(5):1519-31.

PMID:
15364578
43.

Response to therapy in carnitine/acylcarnitine translocase (CACT) deficiency due to a novel missense mutation.

Iacobazzi V, Pasquali M, Singh R, Matern D, Rinaldo P, Amat di San Filippo C, Palmieri F, Longo N.

Am J Med Genet A. 2004 Apr 15;126A(2):150-5.

PMID:
15057979
44.
45.

Aberrant mRNA splicing associated with coding region mutations in children with carnitine-acylcarnitine translocase deficiency.

Hsu BY, Iacobazzi V, Wang Z, Harvie H, Chalmers RA, Saudubray JM, Palmieri F, Ganguly A, Stanley CA.

Mol Genet Metab. 2001 Sep-Oct;74(1-2):248-55.

PMID:
11592821
46.

Genomic organization and mapping of the gene (SLC25A19) encoding the human mitochondrial deoxynucleotide carrier (DNC).

Iacobazzi V, Ventura M, Fiermonte G, Prezioso G, Rocchi M, Palmieri F.

Cytogenet Cell Genet. 2001;93(1-2):40-2.

PMID:
11474176
47.

Functional analysis of mutant human carnitine acylcarnitine translocases in yeast.

IJlst L, van Roermund CW, Iacobazzi V, Oostheim W, Ruiter JP, Williams JC, Palmieri F, Wanders RJ.

Biochem Biophys Res Commun. 2001 Jan 26;280(3):700-6.

PMID:
11162577
48.

Identification of the mitochondrial carnitine carrier in Saccharomyces cerevisiae.

Palmieri L, Lasorsa FM, Iacobazzi V, Runswick MJ, Palmieri F, Walker JE.

FEBS Lett. 1999 Dec 3;462(3):472-6.

49.

Assignment of the oxoglutarate carrier gene (SLC20A4) to human chromosome 17p13.3.

Piccininni S, Iacobazzi V, Lauria G, Rocchi M, Palmieri F.

Cytogenet Cell Genet. 1998;83(3-4):256-7. No abstract available.

PMID:
10072597
50.

The structure and organization of the human carnitine/acylcarnitine translocase (CACT1) gene2.

Iacobazzi V, Naglieri MA, Stanley CA, Wanders RJ, Palmieri F.

Biochem Biophys Res Commun. 1998 Nov 27;252(3):770-4.

PMID:
9837782

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