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Items: 28


Going with the flow: diagnosing a lymphocyte-rich pleural effusion.

Hyams C, Jenkins MH, Daly R, Heys IC, Maskell NA.

Thorax. 2020 Apr;75(4):354-356. doi: 10.1136/thoraxjnl-2019-214293. Epub 2020 Jan 31. No abstract available.


Urinary antigen testing for pneumococcal pneumonia: is there evidence to make its use uncommon in clinical practice?

Hyams C, Williams OM, Williams P.

ERJ Open Res. 2020 Jan 10;6(1). pii: 00223-2019. doi: 10.1183/23120541.00223-2019. eCollection 2020 Jan. Review.


Relative Contributions of Extracellular and Internalized Bacteria to Early Macrophage Proinflammatory Responses to Streptococcus pneumoniae.

Periselneris J, Ercoli G, Pollard T, Chimalapati S, Camberlein E, Szylar G, Hyams C, Tomlinson G, Petersen FC, Floto RA, Noursadeghi M, Brown JS.

mBio. 2019 Sep 24;10(5). pii: e02144-19. doi: 10.1128/mBio.02144-19.


Pneumonitis: a serious adverse effect of PD-L1 inhibitors including pembrolizumab.

Rickard F, Hyams C, Low AT.

BMJ Case Rep. 2018 May 7;2018. pii: bcr-2018-224485. doi: 10.1136/bcr-2018-224485.


Is this still just sarcoidosis, or should we a-DRESS a different diagnosis?

Rolls S, Hyams C, Sheaff M, O'Shaughnessy TC.

BMJ Case Rep. 2015 Jun 29;2015. pii: bcr2014207778. doi: 10.1136/bcr-2014-207778.


Importance of bacterial replication and alveolar macrophage-independent clearance mechanisms during early lung infection with Streptococcus pneumoniae.

Camberlein E, Cohen JM, José R, Hyams CJ, Callard R, Chimalapati S, Yuste J, Edwards LA, Marshall H, van Rooijen N, Noursadeghi M, Brown JS.

Infect Immun. 2015 Mar;83(3):1181-9. doi: 10.1128/IAI.02788-14. Epub 2015 Jan 12.


Successful use of blood pleurodesis to resolve an iatrogenic persistent pneumothorax in a patient with pulmonary tuberculosis.

Shaukat M, Hyams C, Macavei VM, O'Shaughnessy TC.

BMJ Case Rep. 2014 Sep 19;2014. pii: bcr2014206710. doi: 10.1136/bcr-2014-206710.


Clinical features, microbiology and surgical outcomes of infective endocarditis: a 13-year study from a UK tertiary cardiothoracic referral centre.

Marks DJ, Hyams C, Koo CY, Pavlou M, Robbins J, Koo CS, Rodger G, Huggett JF, Yap J, Macrae MB, Swanton RH, Zumla AI, Miller RF.

QJM. 2015 Mar;108(3):219-29. doi: 10.1093/qjmed/hcu188. Epub 2014 Sep 15.


An unusual cause of a fall: an unusual presentation of lung carcinoma.

Kowa XY, Hyams C, Farrugia M, Lightowlers S.

BMJ Case Rep. 2014 May 7;2014. pii: bcr2013203019. doi: 10.1136/bcr-2013-203019.


The utility of different bioinformatics algorithms for genotypic HIV-1 tropism testing in a large clinical cohort with multiple subtypes.

Bartlett AD, MaCartney MJ, Conibear TC, Feyertag F, Smith CJ, Johnson MA, Hyams C, Garcia-Diaz A, McCormick AL, Booth C, Robertson DL, Webster DP.

AIDS. 2014 Jul 17;28(11):1611-7. doi: 10.1097/QAD.0000000000000288.


Serological cross reactivity to CMV and EBV causes problems in the diagnosis of acute hepatitis E virus infection.

Hyams C, Mabayoje DA, Copping R, Maranao D, Patel M, Labbett W, Haque T, Webster DP.

J Med Virol. 2014 Mar;86(3):478-83. doi: 10.1002/jmv.23827. Epub 2013 Nov 8.


Acute psychosis caused by hypothyroidism following radioactive iodine treatment of Graves' disease.

Hyams C, Joshi P, Foster P, Katz J.

JRSM Short Rep. 2013 Apr;4(4):26. doi: 10.1177/2042533313476858. Epub 2013 Mar 25. No abstract available.


A prospective study of early removal of the urethral catheter after colorectal surgery in patients having epidural analgesia as part of the Enhanced Recovery After Surgery programme.

Stubbs BM, Badcock KJ, Hyams C, Rizal FE, Warren S, Francis D.

Colorectal Dis. 2013 Jun;15(6):733-6. doi: 10.1111/codi.12124.


Streptococcus pneumoniae capsular serotype invasiveness correlates with the degree of factor H binding and opsonization with C3b/iC3b.

Hyams C, Trzcinski K, Camberlein E, Weinberger DM, Chimalapati S, Noursadeghi M, Lipsitch M, Brown JS.

Infect Immun. 2013 Jan;81(1):354-63. doi: 10.1128/IAI.00862-12. Epub 2012 Nov 12.


An unusual case of incomplete Kawasaki disease in an adolescent returning from holiday in Montana.

Hyams C, Day TG, Ramroop S, Paget S, Howard S, McMillan M, Vora S, de Keyser P.

Pediatr Cardiol. 2012 Oct;33(7):1196-9. doi: 10.1007/s00246-012-0246-3. Epub 2012 Mar 8.


Changes in capsular serotype alter the surface exposure of pneumococcal adhesins and impact virulence.

Sanchez CJ, Hinojosa CA, Shivshankar P, Hyams C, Camberlein E, Brown JS, Orihuela CJ.

PLoS One. 2011;6(10):e26587. doi: 10.1371/journal.pone.0026587. Epub 2011 Oct 19.


Effects of Streptococcus pneumoniae strain background on complement resistance.

Hyams C, Opel S, Hanage W, Yuste J, Bax K, Henriques-Normark B, Spratt BG, Brown JS.

PLoS One. 2011;6(10):e24581. doi: 10.1371/journal.pone.0024581. Epub 2011 Oct 13.


Protective contributions against invasive Streptococcus pneumoniae pneumonia of antibody and Th17-cell responses to nasopharyngeal colonisation.

Cohen JM, Khandavilli S, Camberlein E, Hyams C, Baxendale HE, Brown JS.

PLoS One. 2011;6(10):e25558. doi: 10.1371/journal.pone.0025558. Epub 2011 Oct 7.


Characterization of a new mouse model of empyema and the mechanisms of pleural invasion by Streptococcus pneumoniae.

Wilkosz S, Edwards LA, Bielsa S, Hyams C, Taylor A, Davies RJ, Laurent GJ, Chambers RC, Brown JS, Lee YC.

Am J Respir Cell Mol Biol. 2012 Feb;46(2):180-7. doi: 10.1165/rcmb.2011-0182OC. Epub 2011 Sep 1.


Priming innate immune responses to infection by cyclooxygenase inhibition kills antibiotic-susceptible and -resistant bacteria.

Stables MJ, Newson J, Ayoub SS, Brown J, Hyams CJ, Gilroy DW.

Blood. 2010 Oct 21;116(16):2950-9. doi: 10.1182/blood-2010-05-284844. Epub 2010 Jul 6.


Impaired opsonization with complement and phagocytosis of Streptococcus pyogenes in sera from subjects with inherited C2 deficiency.

Yuste J, Sen A, Truedsson L, Jönsson G, Hyams C, Cohen JM, Camberlein E, Sriskandan S, Brown JS.

Microbes Infect. 2010 Aug;12(8-9):626-34. doi: 10.1016/j.micinf.2010.04.004. Epub 2010 Apr 22.


C3b/iC3b deposition on Streptococcus pneumoniae is not affected by HIV infection.

Hyams C, Tam JC, Brown JS, Gordon SB.

PLoS One. 2010 Jan 26;5(1):e8902. doi: 10.1371/journal.pone.0008902.


Streptococcus pneumoniae resistance to complement-mediated immunity is dependent on the capsular serotype.

Hyams C, Yuste J, Bax K, Camberlein E, Weiser JN, Brown JS.

Infect Immun. 2010 Feb;78(2):716-25. doi: 10.1128/IAI.01056-09. Epub 2009 Nov 30.


The Streptococcus pneumoniae capsule inhibits complement activity and neutrophil phagocytosis by multiple mechanisms.

Hyams C, Camberlein E, Cohen JM, Bax K, Brown JS.

Infect Immun. 2010 Feb;78(2):704-15. doi: 10.1128/IAI.00881-09. Epub 2009 Nov 30.


The effects of PspC on complement-mediated immunity to Streptococcus pneumoniae vary with strain background and capsular serotype.

Yuste J, Khandavilli S, Ansari N, Muttardi K, Ismail L, Hyams C, Weiser J, Mitchell T, Brown JS.

Infect Immun. 2010 Jan;78(1):283-92. doi: 10.1128/IAI.00541-09. Epub 2009 Nov 2.


Impaired opsonization with C3b and phagocytosis of Streptococcus pneumoniae in sera from subjects with defects in the classical complement pathway.

Yuste J, Sen A, Truedsson L, Jönsson G, Tay LS, Hyams C, Baxendale HE, Goldblatt F, Botto M, Brown JS.

Infect Immun. 2008 Aug;76(8):3761-70. doi: 10.1128/IAI.00291-08. Epub 2008 Jun 9.


Roles of the alternative complement pathway and C1q during innate immunity to Streptococcus pyogenes.

Yuste J, Ali S, Sriskandan S, Hyams C, Botto M, Brown JS.

J Immunol. 2006 May 15;176(10):6112-20.


Serological evidence of arboviral infections among humans of coastal Kenya.

Morrill JC, Johnson BK, Hyams C, Okoth F, Tukei PM, Mugambi M, Woody J.

J Trop Med Hyg. 1991 Jun;94(3):166-8.


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