Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 233

1.

Enterovirus infection during pregnancy is inversely associated with atopic disease in the offspring.

Korhonen L, Seiskari T, Lehtonen J, Puustinen L, Surcel HM, Haapala AM, Niemelä O, Virtanen SM, Honkanen H, Karjalainen M, Ilonen J, Veijola R, Knip M, Lönnrot M, Hyöty H.

Clin Exp Allergy. 2018 Sep 19. doi: 10.1111/cea.13280. [Epub ahead of print]

PMID:
30230072
2.

Molecular epidemiology of enteroviruses in young children at increased risk of type 1 diabetes.

Sioofy-Khojine AB, Oikarinen S, Honkanen H, Huhtala H, Lehtonen JP, Briese T, Hyöty H; TEDDY Study Group.

PLoS One. 2018 Sep 7;13(9):e0201959. doi: 10.1371/journal.pone.0201959. eCollection 2018.

3.

Dynamics of Plasma Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes - Type 1 Diabetes Prediction and Prevention Study (DIPP).

Lamichhane S, Ahonen L, Dyrlund TS, Kemppainen E, Siljander H, Hyöty H, Ilonen J, Toppari J, Veijola R, Hyötyläinen T, Knip M, Oresic M.

Sci Rep. 2018 Jul 13;8(1):10635. doi: 10.1038/s41598-018-28907-8.

4.

Strain-Level Analysis of Mother-to-Child Bacterial Transmission during the First Few Months of Life.

Yassour M, Jason E, Hogstrom LJ, Arthur TD, Tripathi S, Siljander H, Selvenius J, Oikarinen S, Hyöty H, Virtanen SM, Ilonen J, Ferretti P, Pasolli E, Tett A, Asnicar F, Segata N, Vlamakis H, Lander ES, Huttenhower C, Knip M, Xavier RJ.

Cell Host Microbe. 2018 Jul 11;24(1):146-154.e4. doi: 10.1016/j.chom.2018.06.007.

PMID:
30001517
5.

Short-term direct contact with soil and plant materials leads to an immediate increase in diversity of skin microbiota.

Grönroos M, Parajuli A, Laitinen OH, Roslund MI, Vari HK, Hyöty H, Puhakka R, Sinkkonen A.

Microbiologyopen. 2018 May 29:e00645. doi: 10.1002/mbo3.645. [Epub ahead of print]

6.

Nature-derived microbiota exposure as a novel immunomodulatory approach.

Nurminen N, Lin J, Grönroos M, Puhakka R, Kramna L, Vari HK, Viskari H, Oikarinen S, Roslund M, Parajuli A, Tyni I, Cinek O, Laitinen O, Hyöty H, Sinkkonen A.

Future Microbiol. 2018 Jun 1;13:737-744. doi: 10.2217/fmb-2017-0286. Epub 2018 May 17.

PMID:
29771153
7.

Higher parental occupational social contact is associated with a reduced risk of incident pediatric type 1 diabetes: Mediation through molecular enteroviral indices.

Ponsonby AL, Pezic A, Cameron FJ, Rodda C, Kemp AS, Carlin JB, Hyoty H, Sioofy-Khojine A, Dwyer T, Ellis JA, Craig ME.

PLoS One. 2018 Apr 17;13(4):e0193992. doi: 10.1371/journal.pone.0193992. eCollection 2018.

8.

Half-lives of PAHs and temporal microbiota changes in commonly used urban landscaping materials.

Roslund MI, Grönroos M, Rantalainen AL, Jumpponen A, Romantschuk M, Parajuli A, Hyöty H, Laitinen O, Sinkkonen A.

PeerJ. 2018 Mar 19;6:e4508. doi: 10.7717/peerj.4508. eCollection 2018.

9.

First trimester enterovirus IgM and beta cell autoantibodies in mothers to children affected by type 1 diabetes autoimmunity before 7 years of age.

Lind A, Lynch KF, Lundgren M, Lernmark Å, Almgren P, Ramelius A, Puustinen L, Hyöty H, Lundstig A.

J Reprod Immunol. 2018 Jun;127:1-6. doi: 10.1016/j.jri.2018.02.004. Epub 2018 Mar 2.

PMID:
29550618
10.

Urbanization Reduces Transfer of Diverse Environmental Microbiota Indoors.

Parajuli A, Grönroos M, Siter N, Puhakka R, Vari HK, Roslund MI, Jumpponen A, Nurminen N, Laitinen OH, Hyöty H, Rajaniemi J, Sinkkonen A.

Front Microbiol. 2018 Feb 5;9:84. doi: 10.3389/fmicb.2018.00084. eCollection 2018.

11.

New Coxsackievirus 2Apro and 3Cpro protease antibodies for virus detection and discovery of pathogenic mechanisms.

Laitinen OH, Svedin E, Kapell S, Hankaniemi MM, Larsson PG, Domsgen E, Stone VM, Määttä JAE, Hyöty H, Hytönen VP, Flodström-Tullberg M.

J Virol Methods. 2018 May;255:29-37. doi: 10.1016/j.jviromet.2018.02.001. Epub 2018 Feb 6.

PMID:
29425680
12.

Coxsackievirus B1 infections are associated with the initiation of insulin-driven autoimmunity that progresses to type 1 diabetes.

Sioofy-Khojine AB, Lehtonen J, Nurminen N, Laitinen OH, Oikarinen S, Huhtala H, Pakkanen O, Ruokoranta T, Hankaniemi MM, Toppari J, Vähä-Mäkilä M, Ilonen J, Veijola R, Knip M, Hyöty H.

Diabetologia. 2018 May;61(5):1193-1202. doi: 10.1007/s00125-018-4561-y. Epub 2018 Feb 5.

PMID:
29404673
13.

A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses.

Saarinen NVV, Laiho JE, Richardson SJ, Zeissler M, Stone VM, Marjomäki V, Kantoluoto T, Horwitz MS, Sioofy-Khojine A, Honkimaa A, Hankaniemi MM, Flodström-Tullberg M, Hyöty H, Hytönen VP, Laitinen OH.

Sci Rep. 2018 Jan 8;8(1):33. doi: 10.1038/s41598-017-18495-4.

14.

Quantitative CrAssphage real-time PCR assay derived from data of multiple geographically distant populations.

Cinek O, Mazankova K, Kramna L, Odeh R, Alassaf A, Ibekwe MU, Ahmadov G, Mekki H, Abdullah MA, Elmahi BME, Hyöty H, Rainetova P.

J Med Virol. 2018 Apr;90(4):767-771. doi: 10.1002/jmv.25012. Epub 2018 Jan 19.

PMID:
29297933
15.

A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes.

Stone VM, Hankaniemi MM, Svedin E, Sioofy-Khojine A, Oikarinen S, Hyöty H, Laitinen OH, Hytönen VP, Flodström-Tullberg M.

Diabetologia. 2018 Feb;61(2):476-481. doi: 10.1007/s00125-017-4492-z. Epub 2017 Nov 18.

PMID:
29151123
16.

The abundance of health-associated bacteria is altered in PAH polluted soils-Implications for health in urban areas?

Parajuli A, Grönroos M, Kauppi S, Płociniczak T, Roslund MI, Galitskaya P, Laitinen OH, Hyöty H, Jumpponen A, Strömmer R, Romantschuk M, Hui N, Sinkkonen A.

PLoS One. 2017 Nov 16;12(11):e0187852. doi: 10.1371/journal.pone.0187852. eCollection 2017.

17.

Enterovirus-associated changes in blood transcriptomic profiles of children with genetic susceptibility to type 1 diabetes.

Lietzen N, An LTT, Jaakkola MK, Kallionpää H, Oikarinen S, Mykkänen J, Knip M, Veijola R, Ilonen J, Toppari J, Hyöty H, Lahesmaa R, Elo LL.

Diabetologia. 2018 Feb;61(2):381-388. doi: 10.1007/s00125-017-4460-7. Epub 2017 Nov 8.

PMID:
29119244
18.

Correction to: Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study.

Lönnrot M, Lynch KF, Elding Larsson H, Lernmark Å, Rewers MJ, Törn C, Burkhardt BR, Briese T, Hagopian WA, She JX, Simell OG, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Hyöty H; TEDDY Study Group.

Diabetologia. 2018 Jan;61(1):254. doi: 10.1007/s00125-017-4487-9.

PMID:
29080005
19.

Association Between Early-Life Antibiotic Use and the Risk of Islet or Celiac Disease Autoimmunity.

Kemppainen KM, Vehik K, Lynch KF, Larsson HE, Canepa RJ, Simell V, Koletzko S, Liu E, Simell OG, Toppari J, Ziegler AG, Rewers MJ, Lernmark Å, Hagopian WA, She JX, Akolkar B, Schatz DA, Atkinson MA, Blaser MJ, Krischer JP, Hyöty H, Agardh D, Triplett EW; Environmental Determinants of Diabetes in the Young (TEDDY) Study Group.

JAMA Pediatr. 2017 Dec 1;171(12):1217-1225. doi: 10.1001/jamapediatrics.2017.2905.

PMID:
29052687
20.

Exocrine pancreas function decreases during the progression of the beta-cell damaging process in young prediabetic children.

Kondrashova A, Nurminen N, Lehtonen J, Hyöty M, Toppari J, Ilonen J, Veijola R, Knip M, Hyöty H.

Pediatr Diabetes. 2018 May;19(3):398-402. doi: 10.1111/pedi.12592. Epub 2017 Oct 17.

PMID:
29044779
21.

Pandemrix® vaccination is not associated with increased risk of islet autoimmunity or type 1 diabetes in the TEDDY study children.

Elding Larsson H, Lynch KF, Lönnrot M, Haller MJ, Lernmark Å, Hagopian WA, She JX, Simell O, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Rewers MJ, Hyöty H; TEDDY Study Group.

Diabetologia. 2018 Jan;61(1):193-202. doi: 10.1007/s00125-017-4448-3. Epub 2017 Oct 9.

22.

Gestational respiratory infections interacting with offspring HLA and CTLA-4 modifies incident β-cell autoantibodies.

Lynch KF, Lee HS, Törn C, Vehik K, Krischer JP, Larsson HE, Haller MJ, Hagopian WA, Rewers MJ, She JX, Simell OG, Toppari J, Ziegler AG, Akolkar B, Hyöty H, Bonifacio E, Lernmark Å; TEDDY Study Group.

J Autoimmun. 2018 Jan;86:93-103. doi: 10.1016/j.jaut.2017.09.005. Epub 2017 Sep 21.

PMID:
28941965
23.

Live attenuated enterovirus vaccine (OPV) is not associated with islet autoimmunity in children with genetic susceptibility to type 1 diabetes: prospective cohort study.

Viskari H, Oikarinen S, Hoppu S, Vuorinen T, Huhtala H, Toppari J, Veijola R, Ilonen J, Knip M, Hyöty H.

Diabetologia. 2018 Jan;61(1):203-209. doi: 10.1007/s00125-017-4410-4. Epub 2017 Sep 2.

PMID:
28866779
24.

Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study.

Lönnrot M, Lynch KF, Elding Larsson H, Lernmark Å, Rewers MJ, Törn C, Burkhardt BR, Briese T, Hagopian WA, She JX, Simell OG, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Hyöty H; TEDDY Study Group.

Diabetologia. 2017 Oct;60(10):1931-1940. doi: 10.1007/s00125-017-4365-5. Epub 2017 Aug 2. Erratum in: Diabetologia. 2018 Jan;61(1):254.

PMID:
28770319
25.

Early childhood infections precede development of beta-cell autoimmunity and type 1 diabetes in children with HLA-conferred disease risk.

Mustonen N, Siljander H, Peet A, Tillmann V, Härkönen T, Ilonen J, Hyöty H, Knip M; DIABIMMUNE Study Group.

Pediatr Diabetes. 2018 Mar;19(2):293-299. doi: 10.1111/pedi.12547. Epub 2017 Jun 9.

PMID:
28597957
26.

Optimized production and purification of Coxsackievirus B1 vaccine and its preclinical evaluation in a mouse model.

Hankaniemi MM, Laitinen OH, Stone VM, Sioofy-Khojine A, Määttä JAE, Larsson PG, Marjomäki V, Hyöty H, Flodström-Tullberg M, Hytönen VP.

Vaccine. 2017 Jun 27;35(30):3718-3725. doi: 10.1016/j.vaccine.2017.05.057. Epub 2017 Jun 1.

PMID:
28579231
27.

Vipie: web pipeline for parallel characterization of viral populations from multiple NGS samples.

Lin J, Kramna L, Autio R, Hyöty H, Nykter M, Cinek O.

BMC Genomics. 2017 May 15;18(1):378. doi: 10.1186/s12864-017-3721-7.

28.

Next-Generation Sequencing Combined with Specific PCR Assays To Determine the Bacterial 16S rRNA Gene Profiles of Middle Ear Fluid Collected from Children with Acute Otitis Media.

Sillanpää S, Kramna L, Oikarinen S, Sipilä M, Rautiainen M, Aittoniemi J, Laranne J, Hyöty H, Cinek O.

mSphere. 2017 Mar 22;2(2). pii: e00006-17. doi: 10.1128/mSphere.00006-17. eCollection 2017 Mar-Apr.

29.

Correction: B-Cell Responses to Human Bocaviruses 1-4: New Insights from a Childhood Follow-Up Study.

Kantola K, Hedman L, Tanner L, Simell V, Mäkinen M, Partanen J, Sadeghi M, Veijola R, Knip M, Ilonen J, Hyöty H, Toppari J, Simell O, Hedman K, Söderlund-Venermo M.

PLoS One. 2017 Feb 8;12(2):e0172078. doi: 10.1371/journal.pone.0172078. eCollection 2017.

30.

Detection and localization of viral infection in the pancreas of patients with type 1 diabetes using short fluorescently-labelled oligonucleotide probes.

Busse N, Paroni F, Richardson SJ, Laiho JE, Oikarinen M, Frisk G, Hyöty H, de Koning E, Morgan NG, Maedler K.

Oncotarget. 2017 Feb 21;8(8):12620-12636. doi: 10.18632/oncotarget.14896.

31.

Circulating CXCR5+PD-1+ICOS+ Follicular T Helper Cells Are Increased Close to the Diagnosis of Type 1 Diabetes in Children With Multiple Autoantibodies.

Viisanen T, Ihantola EL, Näntö-Salonen K, Hyöty H, Nurminen N, Selvenius J, Juutilainen A, Moilanen L, Pihlajamäki J, Veijola R, Toppari J, Knip M, Ilonen J, Kinnunen T.

Diabetes. 2017 Feb;66(2):437-447. doi: 10.2337/db16-0714. Epub 2016 Oct 10.

32.

Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary?

Campbell-Thompson ML, Atkinson MA, Butler AE, Giepmans BN, von Herrath MG, Hyöty H, Kay TW, Morgan NG, Powers AC, Pugliese A, Richardson SJ, In't Veld PA.

Diabetologia. 2017 Apr;60(4):753-755. doi: 10.1007/s00125-016-4195-x. Epub 2017 Jan 9. No abstract available.

33.

Detection of enteroviruses in stools precedes islet autoimmunity by several months: possible evidence for slowly operating mechanisms in virus-induced autoimmunity.

Honkanen H, Oikarinen S, Nurminen N, Laitinen OH, Huhtala H, Lehtonen J, Ruokoranta T, Hankaniemi MM, Lecouturier V, Almond JW, Tauriainen S, Simell O, Ilonen J, Veijola R, Viskari H, Knip M, Hyöty H.

Diabetologia. 2017 Mar;60(3):424-431. doi: 10.1007/s00125-016-4177-z. Epub 2017 Jan 9.

PMID:
28070615
34.

Coxsackie-adenovirus receptor expression is enhanced in pancreas from patients with type 1 diabetes.

Hodik M, Anagandula M, Fuxe J, Krogvold L, Dahl-Jørgensen K, Hyöty H, Sarmiento L, Frisk G; POD-V Consortium.

BMJ Open Diabetes Res Care. 2016 Nov 25;4(1):e000219. eCollection 2016.

35.

Imbalance of bacteriome profiles within the Finnish Diabetes Prediction and Prevention study: Parallel use of 16S profiling and virome sequencing in stool samples from children with islet autoimmunity and matched controls.

Cinek O, Kramna L, Lin J, Oikarinen S, Kolarova K, Ilonen J, Simell O, Veijola R, Autio R, Hyöty H.

Pediatr Diabetes. 2017 Nov;18(7):588-598. doi: 10.1111/pedi.12468. Epub 2016 Nov 17.

PMID:
27860030
36.

Factors That Increase Risk of Celiac Disease Autoimmunity After a Gastrointestinal Infection in Early Life.

Kemppainen KM, Lynch KF, Liu E, Lönnrot M, Simell V, Briese T, Koletzko S, Hagopian W, Rewers M, She JX, Simell O, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Lernmark Å, Hyöty H, Triplett EW, Agardh D; TEDDY Study Group.

Clin Gastroenterol Hepatol. 2017 May;15(5):694-702.e5. doi: 10.1016/j.cgh.2016.10.033. Epub 2016 Nov 10.

37.

Human enterovirus and rhinovirus infections are associated with otitis media in a prospective birth cohort study.

Seppälä E, Sillanpää S, Nurminen N, Huhtala H, Toppari J, Ilonen J, Veijola R, Knip M, Sipilä M, Laranne J, Oikarinen S, Hyöty H.

J Clin Virol. 2016 Dec;85:1-6. doi: 10.1016/j.jcv.2016.10.010. Epub 2016 Oct 20.

PMID:
27780081
38.

Natural Development of Antibodies against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis Protein Antigens during the First 13 Years of Life.

Borges IC, Andrade DC, Cardoso MR, Toppari J, Vähä-Mäkilä M, Ilonen J, Knip M, Hyöty H, Veijola R, Simell O, Jartti T, Käyhty H, Ruuskanen O, Nascimento-Carvalho CM.

Clin Vaccine Immunol. 2016 Nov 4;23(11):878-883. Print 2016 Nov.

39.

Moraxella catarrhalis Might Be More Common than Expected in Acute Otitis Media in Young Finnish Children.

Sillanpää S, Oikarinen S, Sipilä M, Kramna L, Rautiainen M, Huhtala H, Aittoniemi J, Laranne J, Hyöty H, Cinek O.

J Clin Microbiol. 2016 Sep;54(9):2373-9. doi: 10.1128/JCM.01146-16. Epub 2016 Jul 13.

40.

Viruses in type 1 diabetes.

Hyöty H.

Pediatr Diabetes. 2016 Jul;17 Suppl 22:56-64. doi: 10.1111/pedi.12370. Review.

PMID:
27411438
41.

Antibiotic resistance in pathogens causing acute otitis media in Finnish children.

Sillanpää S, Sipilä M, Hyöty H, Rautiainen M, Laranne J.

Int J Pediatr Otorhinolaryngol. 2016 Jun;85:91-4. doi: 10.1016/j.ijporl.2016.03.037. Epub 2016 Apr 11.

PMID:
27240503
42.

Relative sensitivity of immunohistochemistry, multiple reaction monitoring mass spectrometry, in situ hybridization and PCR to detect Coxsackievirus B1 in A549 cells.

Laiho JE, Oikarinen M, Richardson SJ, Frisk G, Nyalwidhe J, Burch TC, Morris MA, Oikarinen S, Pugliese A, Dotta F, Campbell-Thompson M, Nadler J, Morgan NG, Hyöty H; JDRF nPOD-Virus Group.

J Clin Virol. 2016 Apr;77:21-8. doi: 10.1016/j.jcv.2016.01.015. Epub 2016 Feb 2.

43.

Development and maturation of norovirus antibodies in childhood.

Blazevic V, Malm M, Honkanen H, Knip M, Hyöty H, Vesikari T.

Microbes Infect. 2016 Apr;18(4):263-9. doi: 10.1016/j.micinf.2015.12.004. Epub 2015 Dec 25.

44.

Serum 25-Hydroxyvitamin D Concentrations in Children Progressing to Autoimmunity and Clinical Type 1 Diabetes.

Mäkinen M, Mykkänen J, Koskinen M, Simell V, Veijola R, Hyöty H, Ilonen J, Knip M, Simell O, Toppari J.

J Clin Endocrinol Metab. 2016 Feb;101(2):723-9. doi: 10.1210/jc.2015-3504. Epub 2015 Dec 22.

45.

B-Cell Responses to Human Bocaviruses 1-4: New Insights from a Childhood Follow-Up Study.

Kantola K, Hedman L, Tanner L, Simell V, Mäkinen M, Partanen J, Sadeghi M, Veijola R, Knip M, Ilonen J, Hyöty H, Toppari J, Simell O, Hedman K, Söderlund-Venermo M.

PLoS One. 2015 Sep 29;10(9):e0139096. doi: 10.1371/journal.pone.0139096. eCollection 2015. Erratum in: PLoS One. 2017 Feb 8;12 (2):e0172078.

46.

Influenza A virus antibodies show no association with pancreatic islet autoantibodies in children genetically predisposed to type 1 diabetes.

Kondrashova A, Nurminen N, Patrikainen M, Huhtala H, Lehtonen J, Toppari J, Ilonen J, Simell OG, Veijola R, Knip M, Hyöty H.

Diabetologia. 2015 Nov;58(11):2592-5. doi: 10.1007/s00125-015-3723-4. Epub 2015 Aug 8.

PMID:
26253765
47.

Application of bioinformatics in probe design enables detection of enteroviruses on different taxonomic levels by advanced in situ hybridization technology.

Laiho JE, Oikarinen S, Oikarinen M, Larsson PG, Stone VM, Hober D, Oberste S, Flodström-Tullberg M, Isola J, Hyöty H.

J Clin Virol. 2015 Aug;69:165-71. doi: 10.1016/j.jcv.2015.06.085. Epub 2015 Jun 23.

PMID:
26209400
48.

Multiple consecutive norovirus infections in the first 2 years of life.

Blazevic V, Malm M, Salminen M, Oikarinen S, Hyöty H, Veijola R, Vesikari T.

Eur J Pediatr. 2015 Dec;174(12):1679-83. doi: 10.1007/s00431-015-2591-8. Epub 2015 Jul 9.

49.

Investigation of CTLA-4-318C/T gene polymorphism in cases with type 1 diabetes of Azerbaijan, Northwest Iran.

Almasi S, Aliparasti MR, Aliasgarzadeh A, Abd-Nikfarjam B, Hyöty H, Knip M, Feizi H, Sioofy-Khojine A, Rahnama B.

Immunol Lett. 2015 Aug;166(2):134-9. doi: 10.1016/j.imlet.2015.05.021. Epub 2015 Jun 5.

PMID:
26051683
50.

High-throughput multiplex quantitative polymerase chain reaction method for Giardia lamblia and Cryptosporidium species detection in stool samples.

Nurminen N, Juuti R, Oikarinen S, Fan YM, Lehto KM, Mangani C, Maleta K, Ashorn P, Hyöty H.

Am J Trop Med Hyg. 2015 Jun;92(6):1222-6. doi: 10.4269/ajtmh.15-0054. Epub 2015 Apr 27.

Supplemental Content

Support Center