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Items: 31

1.

The human orphan nuclear receptor tailless (TLX, NR2E1) is druggable.

Benod C, Villagomez R, Filgueira CS, Hwang PK, Leonard PG, Poncet-Montange G, Rajagopalan S, Fletterick RJ, Gustafsson JÅ, Webb P.

PLoS One. 2014 Jun 17;9(6):e99440. doi: 10.1371/journal.pone.0099440. eCollection 2014.

2.

Flexible antibodies with nonprotein hinges.

Capon DJ, Kaneko N, Yoshimori T, Shimada T, Wurm FM, Hwang PK, Tong X, Adams SA, Simmons G, Sato TA, Tanaka K.

Proc Jpn Acad Ser B Phys Biol Sci. 2011;87(9):603-16.

3.

Conformation switching of clathrin light chain regulates clathrin lattice assembly.

Wilbur JD, Hwang PK, Ybe JA, Lane M, Sellers BD, Jacobson MP, Fletterick RJ, Brodsky FM.

Dev Cell. 2010 May 18;18(5):841-8. doi: 10.1016/j.devcel.2010.04.007.

4.

Accommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domain.

Wilbur JD, Hwang PK, Brodsky FM, Fletterick RJ.

Acta Crystallogr D Biol Crystallogr. 2010 Mar;66(Pt 3):314-8. doi: 10.1107/S0907444909054535. Epub 2010 Feb 12.

5.

A dimer-specific function of the transcription factor NFATp.

Falvo JV, Lin CH, Tsytsykova AV, Hwang PK, Thanos D, Goldfeld AE, Maniatis T.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19637-42. doi: 10.1073/pnas.0810648105. Epub 2008 Dec 5.

6.

Actin binding by Hip1 (huntingtin-interacting protein 1) and Hip1R (Hip1-related protein) is regulated by clathrin light chain.

Wilbur JD, Chen CY, Manalo V, Hwang PK, Fletterick RJ, Brodsky FM.

J Biol Chem. 2008 Nov 21;283(47):32870-9. doi: 10.1074/jbc.M802863200. Epub 2008 Sep 12.

7.

Novel binding sites on clathrin and adaptors regulate distinct aspects of coat assembly.

Knuehl C, Chen CY, Manalo V, Hwang PK, Ota N, Brodsky FM.

Traffic. 2006 Dec;7(12):1688-700. Epub 2006 Oct 17.

8.

New faces of the familiar clathrin lattice.

Wilbur JD, Hwang PK, Brodsky FM.

Traffic. 2005 Apr;6(4):346-50. Review.

9.

Clathrin self-assembly involves coordinated weak interactions favorable for cellular regulation.

Wakeham DE, Chen CY, Greene B, Hwang PK, Brodsky FM.

EMBO J. 2003 Oct 1;22(19):4980-90.

10.

Clathrin light and heavy chain interface: alpha-helix binding superhelix loops via critical tryptophans.

Chen CY, Reese ML, Hwang PK, Ota N, Agard D, Brodsky FM.

EMBO J. 2002 Nov 15;21(22):6072-82.

11.

Molecular structures of proteins involved in vesicle fusion.

Ybe JA, Wakeham DE, Brodsky FM, Hwang PK.

Traffic. 2000 Jun;1(6):474-9. Review.

12.

Molecular structures of proteins involved in vesicle coat formation.

Wakeham DE, Ybe JA, Brodsky FM, Hwang PK.

Traffic. 2000 May;1(5):393-8. Review.

13.

Detection of surgical glove integrity.

Sohn RL, Murray MT, Franko A, Hwang PK, Dulchavsky SA, Grimm MJ.

Am Surg. 2000 Mar;66(3):302-6.

PMID:
10759204
14.

Clathrin self-assembly is mediated by a tandemly repeated superhelix.

Ybe JA, Brodsky FM, Hofmann K, Lin K, Liu SH, Chen L, Earnest TN, Fletterick RJ, Hwang PK.

Nature. 1999 May 27;399(6734):371-5.

PMID:
10360576
15.

Crystal structure of neurotrophin-3 homodimer shows distinct regions are used to bind its receptors.

Butte MJ, Hwang PK, Mobley WC, Fletterick RJ.

Biochemistry. 1998 Dec 1;37(48):16846-52.

PMID:
9836577
16.

Distinct phosphorylation signals converge at the catalytic center in glycogen phosphorylases.

Lin K, Hwang PK, Fletterick RJ.

Structure. 1997 Nov 15;5(11):1511-23.

17.

A protein phosphorylation switch at the conserved allosteric site in GP.

Lin K, Rath VL, Dai SC, Fletterick RJ, Hwang PK.

Science. 1996 Sep 13;273(5281):1539-42.

PMID:
8703213
18.

The evolution of an allosteric site in phosphorylase.

Rath VL, Lin K, Hwang PK, Fletterick RJ.

Structure. 1996 Apr 15;4(4):463-73.

19.

Mechanism of regulation in yeast glycogen phosphorylase.

Lin K, Hwang PK, Fletterick RJ.

J Biol Chem. 1995 Nov 10;270(45):26833-9.

20.
21.

Cooperative binding is not required for activation of muscle phosphorylase.

Browner MF, Hwang PK, Fletterick RJ.

Biochemistry. 1992 Nov 24;31(46):11291-6.

PMID:
1445866
22.

Purification and crystallization of glycogen phosphorylase from Saccharomyces cerevisiae.

Rath VL, Hwang PK, Fletterick RJ.

J Mol Biol. 1992 Jun 20;225(4):1027-34.

PMID:
1613787
23.

Molecular analysis of GPH1, the gene encoding glycogen phosphorylase in Saccharomyces cerevisiae.

Hwang PK, Tugendreich S, Fletterick RJ.

Mol Cell Biol. 1989 Apr;9(4):1659-66.

24.

The family of glycogen phosphorylases: structure and function.

Newgard CB, Hwang PK, Fletterick RJ.

Crit Rev Biochem Mol Biol. 1989;24(1):69-99. Review.

PMID:
2667896
25.

Convergent and divergent evolution of regulatory sites in eukaryotic phosphorylases.

Hwang PK, Fletterick RJ.

Nature. 1986 Nov 6-12;324(6092):80-4.

PMID:
3537803
26.

Sequence analysis of the cDNA encoding human liver glycogen phosphorylase reveals tissue-specific codon usage.

Newgard CB, Nakano K, Hwang PK, Fletterick RJ.

Proc Natl Acad Sci U S A. 1986 Nov;83(21):8132-6.

27.

Complete cDNA sequence for rabbit muscle glycogen phosphorylase.

Nakano K, Hwang PK, Fletterick RJ.

FEBS Lett. 1986 Aug 18;204(2):283-7.

28.

Structural relationships in glycogen phosphorylases.

Fletterick RJ, Burke JA, Hwang PK, Nakano K, Newgard CB.

Ann N Y Acad Sci. 1986;478:220-32. Review. No abstract available.

PMID:
3541750
29.

Comparative sequence analysis of rat, rabbit, and human muscle glycogen phosphorylase cDNAs.

Hwang PK, See YP, Vincentini AM, Powers MA, Fletterick RJ, Crerar MM.

Eur J Biochem. 1985 Oct 15;152(2):267-74.

30.

Interaction between hemoglobin subunits in the hemoglobin . haptoglobin complex.

Hwang PK, Greer J.

J Biol Chem. 1980 Apr 10;255(7):3038-41. No abstract available.

31.

Identification of residues involved in the binding of hemoglobin alpha chains to haptoglobin.

Hwang PK, Greer J.

J Biol Chem. 1979 Apr 10;254(7):2265-70. No abstract available.

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