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Items: 1 to 50 of 162

1.

The assembly pathway of complex I in Arabidopsis thaliana.

Ligas J, Pineau E, Bock R, Huynen MA, Meyer EH.

Plant J. 2018 Oct 22. doi: 10.1111/tpj.14133. [Epub ahead of print]

PMID:
30347487
2.

Does mitochondrial DNA evolution in metazoa drive the origin of new mitochondrial proteins?

van Esveld SL, Huynen MA.

IUBMB Life. 2018 Dec;70(12):1240-1250. doi: 10.1002/iub.1940. Epub 2018 Oct 3. Review.

PMID:
30281911
3.

Xrp1 genetically interacts with the ALS-associated FUS orthologue caz and mediates its toxicity.

Mallik M, Catinozzi M, Hug CB, Zhang L, Wagner M, Bussmann J, Bittern J, Mersmann S, Klämbt C, Drexler HCA, Huynen MA, Vaquerizas JM, Storkebaum E.

J Cell Biol. 2018 Nov 5;217(11):3947-3964. doi: 10.1083/jcb.201802151. Epub 2018 Sep 12.

4.

Use of whole genome sequencing to predict Mycobacterium tuberculosis drug resistance in Indonesia.

Chaidir L, Ruesen C, Dutilh BE, Ganiem AR, Andryani A, Apriani L, Huynen MA, Ruslami R, Hill PC, Crevel RV, Alisjahbana B.

J Glob Antimicrob Resist. 2018 Aug 29. pii: S2213-7165(18)30165-6. doi: 10.1016/j.jgar.2018.08.018. [Epub ahead of print]

PMID:
30172045
5.

Isocitrate dehydrogenase 1-mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress.

Lenting K, Khurshed M, Peeters TH, van den Heuvel CNAM, van Lith SAM, de Bitter T, Hendriks W, Span PN, Molenaar RJ, Botman D, Verrijp K, Heerschap A, Ter Laan M, Kusters B, van Ewijk A, Huynen MA, van Noorden CJF, Leenders WPJ.

FASEB J. 2018 Jul 12:fj201800907RR. doi: 10.1096/fj.201800907RR. [Epub ahead of print]

PMID:
30001166
6.

Heterozygous missense variants of LMX1A lead to nonsyndromic hearing impairment and vestibular dysfunction.

Wesdorp M, de Koning Gans PAM, Schraders M, Oostrik J, Huynen MA, Venselaar H, Beynon AJ, van Gaalen J, Piai V, Voermans N, van Rossum MM, Hartel BP, Lelieveld SH, Wiel L, Verbist B, Rotteveel LJ, van Dooren MF, Lichtner P, Kunst HPM, Feenstra I, Admiraal RJC; DOOFNL Consortium, Yntema HG, Hoefsloot LH, Pennings RJE, Kremer H.

Hum Genet. 2018 May 12. doi: 10.1007/s00439-018-1880-5. [Epub ahead of print]

7.

Towards predicting the environmental metabolome from metagenomics with a mechanistic model.

Garza DR, van Verk MC, Huynen MA, Dutilh BE.

Nat Microbiol. 2018 Apr;3(4):456-460. doi: 10.1038/s41564-018-0124-8. Epub 2018 Mar 12.

PMID:
29531366
8.

Large-scale genomic analysis shows association between homoplastic genetic variation in Mycobacterium tuberculosis genes and meningeal or pulmonary tuberculosis.

Ruesen C, Chaidir L, van Laarhoven A, Dian S, Ganiem AR, Nebenzahl-Guimaraes H, Huynen MA, Alisjahbana B, Dutilh BE, van Crevel R.

BMC Genomics. 2018 Feb 5;19(1):122. doi: 10.1186/s12864-018-4498-z.

9.

Haemophilus is overrepresented in the nasopharynx of infants hospitalized with RSV infection and associated with increased viral load and enhanced mucosal CXCL8 responses.

Ederveen THA, Ferwerda G, Ahout IM, Vissers M, de Groot R, Boekhorst J, Timmerman HM, Huynen MA, van Hijum SAFT, de Jonge MI.

Microbiome. 2018 Jan 11;6(1):10. doi: 10.1186/s40168-017-0395-y.

10.

Probabilistic data integration identifies reliable gametocyte-specific proteins and transcripts in malaria parasites.

Meerstein-Kessel L, van der Lee R, Stone W, Lanke K, Baker DA, Alano P, Silvestrini F, Janse CJ, Khan SM, van de Vegte-Bolmer M, Graumans W, Siebelink-Stoter R, Kooij TWA, Marti M, Drakeley C, Campo JJ, van Dam TJP, Sauerwein R, Bousema T, Huynen MA.

Sci Rep. 2018 Jan 11;8(1):410. doi: 10.1038/s41598-017-18840-7.

11.

The Gene Ontology of eukaryotic cilia and flagella.

Roncaglia P, van Dam TJP, Christie KR, Nacheva L, Toedt G, Huynen MA, Huntley RP, Gibson TJ, Lomax J.

Cilia. 2017 Nov 16;6:10. doi: 10.1186/s13630-017-0054-8. eCollection 2017.

12.

Correction for Quainoo et al., "Whole-Genome Sequencing of Bacterial Pathogens: the Future of Nosocomial Outbreak Analysis".

Quainoo S, Coolen JPM, van Hijum SAFT, Huynen MA, Melchers WJG, van Schaik W, Wertheim HFL.

Clin Microbiol Rev. 2017 Nov 1;31(1). pii: e00082-17. doi: 10.1128/CMR.00082-17. Print 2018 Jan. No abstract available.

13.

Regulatory remodeling in the allo-tetraploid frog Xenopus laevis.

Elurbe DM, Paranjpe SS, Georgiou G, van Kruijsbergen I, Bogdanovic O, Gibeaux R, Heald R, Lister R, Huynen MA, van Heeringen SJ, Veenstra GJC.

Genome Biol. 2017 Oct 24;18(1):198. doi: 10.1186/s13059-017-1335-7.

14.

Genome-scale detection of positive selection in nine primates predicts human-virus evolutionary conflicts.

van der Lee R, Wiel L, van Dam TJP, Huynen MA.

Nucleic Acids Res. 2017 Oct 13;45(18):10634-10648. doi: 10.1093/nar/gkx704.

15.

Modest heterologous protection after Plasmodium falciparum sporozoite immunization: a double-blind randomized controlled clinical trial.

Walk J, Reuling IJ, Behet MC, Meerstein-Kessel L, Graumans W, van Gemert GJ, Siebelink-Stoter R, van de Vegte-Bolmer M, Janssen T, Teelen K, de Wilt JHW, de Mast Q, van der Ven AJ, Diez Benavente E, Campino S, Clark TG, Huynen MA, Hermsen CC, Bijker EM, Scholzen A, Sauerwein RW.

BMC Med. 2017 Sep 13;15(1):168. doi: 10.1186/s12916-017-0923-4.

16.

Whole-Genome Sequencing of Bacterial Pathogens: the Future of Nosocomial Outbreak Analysis.

Quainoo S, Coolen JPM, van Hijum SAFT, Huynen MA, Melchers WJG, van Schaik W, Wertheim HFL.

Clin Microbiol Rev. 2017 Oct;30(4):1015-1063. doi: 10.1128/CMR.00016-17. Review. Erratum in: Clin Microbiol Rev. 2017 Nov 1;31(1):.

17.

Interspecies differences in PTH-mediated PKA phosphorylation of the epithelial calcium channel TRPV5.

van Goor MK, Verkaart S, van Dam TJ, Huynen MA, van der Wijst J.

Pflugers Arch. 2017 Oct;469(10):1301-1311. doi: 10.1007/s00424-017-1996-9. Epub 2017 May 22.

18.

Fifteen years of research on oral-facial-digital syndromes: from 1 to 16 causal genes.

Bruel AL, Franco B, Duffourd Y, Thevenon J, Jego L, Lopez E, Deleuze JF, Doummar D, Giles RH, Johnson CA, Huynen MA, Chevrier V, Burglen L, Morleo M, Desguerres I, Pierquin G, Doray B, Gilbert-Dussardier B, Reversade B, Steichen-Gersdorf E, Baumann C, Panigrahi I, Fargeot-Espaliat A, Dieux A, David A, Goldenberg A, Bongers E, Gaillard D, Argente J, Aral B, Gigot N, St-Onge J, Birnbaum D, Phadke SR, Cormier-Daire V, Eguether T, Pazour GJ, Herranz-Pérez V, Goldstein JS, Pasquier L, Loget P, Saunier S, Mégarbané A, Rosnet O, Leroux MR, Wallingford JB, Blacque OE, Nachury MV, Attie-Bitach T, Rivière JB, Faivre L, Thauvin-Robinet C.

J Med Genet. 2017 Jun;54(6):371-380. doi: 10.1136/jmedgenet-2016-104436. Epub 2017 Mar 13. Review.

19.

Identification and evolutionary analysis of tissue-specific isoforms of mitochondrial complex I subunit NDUFV3.

Guerrero-Castillo S, Cabrera-Orefice A, Huynen MA, Arnold S.

Biochim Biophys Acta Bioenerg. 2017 Mar;1858(3):208-217. doi: 10.1016/j.bbabio.2016.12.004. Epub 2016 Dec 15.

20.

Heterochromatic histone modifications at transposons in Xenopus tropicalis embryos.

van Kruijsbergen I, Hontelez S, Elurbe DM, van Heeringen SJ, Huynen MA, Veenstra GJC.

Dev Biol. 2017 Jun 15;426(2):460-471. doi: 10.1016/j.ydbio.2016.08.031. Epub 2016 Sep 14.

21.

Proteomics of Human Dendritic Cell Subsets Reveals Subset-Specific Surface Markers and Differential Inflammasome Function.

Worah K, Mathan TSM, Vu Manh TP, Keerthikumar S, Schreibelt G, Tel J, Duiveman-de Boer T, Sköld AE, van Spriel AB, de Vries IJM, Huynen MA, Wessels HJ, Gloerich J, Dalod M, Lasonder E, Figdor CG, Buschow SI.

Cell Rep. 2016 Sep 13;16(11):2953-2966. doi: 10.1016/j.celrep.2016.08.023.

22.

ATP6AP1 deficiency causes an immunodeficiency with hepatopathy, cognitive impairment and abnormal protein glycosylation.

Jansen EJ, Timal S, Ryan M, Ashikov A, van Scherpenzeel M, Graham LA, Mandel H, Hoischen A, Iancu TC, Raymond K, Steenbergen G, Gilissen C, Huijben K, van Bakel NH, Maeda Y, Rodenburg RJ, Adamowicz M, Crushell E, Koenen H, Adams D, Vodopiutz J, Greber-Platzer S, Müller T, Dueckers G, Morava E, Sykut-Cegielska J, Martens GJ, Wevers RA, Niehues T, Huynen MA, Veltman JA, Stevens TH, Lefeber DJ.

Nat Commun. 2016 May 27;7:11600. doi: 10.1038/ncomms11600.

23.

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

Boldt K, van Reeuwijk J, Lu Q, Koutroumpas K, Nguyen TM, Texier Y, van Beersum SE, Horn N, Willer JR, Mans DA, Dougherty G, Lamers IJ, Coene KL, Arts HH, Betts MJ, Beyer T, Bolat E, Gloeckner CJ, Haidari K, Hetterschijt L, Iaconis D, Jenkins D, Klose F, Knapp B, Latour B, Letteboer SJ, Marcelis CL, Mitic D, Morleo M, Oud MM, Riemersma M, Rix S, Terhal PA, Toedt G, van Dam TJ, de Vrieze E, Wissinger Y, Wu KM, Apic G, Beales PL, Blacque OE, Gibson TJ, Huynen MA, Katsanis N, Kremer H, Omran H, van Wijk E, Wolfrum U, Kepes F, Davis EE, Franco B, Giles RH, Ueffing M, Russell RB, Roepman R; UK10K Rare Diseases Group.

Nat Commun. 2016 May 13;7:11491. doi: 10.1038/ncomms11491.

24.

Immunologic defects in severe mucocutaneous HSV-2 infections: Response to IFN-γ therapy.

Arts P, van de Veerdonk FL, van der Lee R, Langereis MA, Gilissen C, van Zelst-Stams WAG, Huynen MA, van der Meer JWM, van Kuppeveld FJ, Veltman JA, Kullberg BJ, Hoischen A, Netea MG.

J Allergy Clin Immunol. 2016 Sep;138(3):895-898. doi: 10.1016/j.jaci.2016.02.025. Epub 2016 Apr 7. No abstract available.

PMID:
27132219
25.

The origin of the supernumerary subunits and assembly factors of complex I: A treasure trove of pathway evolution.

Elurbe DM, Huynen MA.

Biochim Biophys Acta. 2016 Jul;1857(7):971-9. doi: 10.1016/j.bbabio.2016.03.027. Epub 2016 Apr 15. Review.

26.

CTCF-mediated chromatin loops enclose inducible gene regulatory domains.

Oti M, Falck J, Huynen MA, Zhou H.

BMC Genomics. 2016 Mar 22;17:252. doi: 10.1186/s12864-016-2516-6.

27.

CCDC115 Deficiency Causes a Disorder of Golgi Homeostasis with Abnormal Protein Glycosylation.

Jansen JC, Cirak S, van Scherpenzeel M, Timal S, Reunert J, Rust S, Pérez B, Vicogne D, Krawitz P, Wada Y, Ashikov A, Pérez-Cerdá C, Medrano C, Arnoldy A, Hoischen A, Huijben K, Steenbergen G, Quelhas D, Diogo L, Rymen D, Jaeken J, Guffon N, Cheillan D, van den Heuvel LP, Maeda Y, Kaiser O, Schara U, Gerner P, van den Boogert MA, Holleboom AG, Nassogne MC, Sokal E, Salomon J, van den Bogaart G, Drenth JP, Huynen MA, Veltman JA, Wevers RA, Morava E, Matthijs G, Foulquier F, Marquardt T, Lefeber DJ.

Am J Hum Genet. 2016 Feb 4;98(2):310-21. doi: 10.1016/j.ajhg.2015.12.010. Epub 2016 Jan 28.

28.

TMEM199 Deficiency Is a Disorder of Golgi Homeostasis Characterized by Elevated Aminotransferases, Alkaline Phosphatase, and Cholesterol and Abnormal Glycosylation.

Jansen JC, Timal S, van Scherpenzeel M, Michelakakis H, Vicogne D, Ashikov A, Moraitou M, Hoischen A, Huijben K, Steenbergen G, van den Boogert MA, Porta F, Calvo PL, Mavrikou M, Cenacchi G, van den Bogaart G, Salomon J, Holleboom AG, Rodenburg RJ, Drenth JP, Huynen MA, Wevers RA, Morava E, Foulquier F, Veltman JA, Lefeber DJ.

Am J Hum Genet. 2016 Feb 4;98(2):322-30. doi: 10.1016/j.ajhg.2015.12.011. Epub 2016 Jan 28.

29.

Systematic Phenomics Analysis Deconvolutes Genes Mutated in Intellectual Disability into Biologically Coherent Modules.

Kochinke K, Zweier C, Nijhof B, Fenckova M, Cizek P, Honti F, Keerthikumar S, Oortveld MA, Kleefstra T, Kramer JM, Webber C, Huynen MA, Schenck A.

Am J Hum Genet. 2016 Jan 7;98(1):149-64. doi: 10.1016/j.ajhg.2015.11.024.

30.

OFIP/KIAA0753 forms a complex with OFD1 and FOR20 at pericentriolar satellites and centrosomes and is mutated in one individual with oral-facial-digital syndrome.

Chevrier V, Bruel AL, Van Dam TJ, Franco B, Lo Scalzo M, Lembo F, Audebert S, Baudelet E, Isnardon D, Bole A, Borg JP, Kuentz P, Thevenon J, Burglen L, Faivre L, Rivière JB, Huynen MA, Birnbaum D, Rosnet O, Thauvin-Robinet C.

Hum Mol Genet. 2016 Feb 1;25(3):497-513. doi: 10.1093/hmg/ddv488. Epub 2015 Dec 7.

PMID:
26643951
31.

TMEM107 recruits ciliopathy proteins to subdomains of the ciliary transition zone and causes Joubert syndrome.

Lambacher NJ, Bruel AL, van Dam TJ, Szymańska K, Slaats GG, Kuhns S, McManus GJ, Kennedy JE, Gaff K, Wu KM, van der Lee R, Burglen L, Doummar D, Rivière JB, Faivre L, Attié-Bitach T, Saunier S, Curd A, Peckham M, Giles RH, Johnson CA, Huynen MA, Thauvin-Robinet C, Blacque OE.

Nat Cell Biol. 2016 Jan;18(1):122-31. doi: 10.1038/ncb3273. Epub 2015 Nov 23.

32.

WeGET: predicting new genes for molecular systems by weighted co-expression.

Szklarczyk R, Megchelenbrink W, Cizek P, Ledent M, Velemans G, Szklarczyk D, Huynen MA.

Nucleic Acids Res. 2016 Jan 4;44(D1):D567-73. doi: 10.1093/nar/gkv1228. Epub 2015 Nov 17.

33.

Integrative Genomics-Based Discovery of Novel Regulators of the Innate Antiviral Response.

van der Lee R, Feng Q, Langereis MA, Ter Horst R, Szklarczyk R, Netea MG, Andeweg AC, van Kuppeveld FJ, Huynen MA.

PLoS Comput Biol. 2015 Oct 20;11(10):e1004553. doi: 10.1371/journal.pcbi.1004553. eCollection 2015 Oct.

34.

Evolution and structural organization of the mitochondrial contact site (MICOS) complex and the mitochondrial intermembrane space bridging (MIB) complex.

Huynen MA, Mühlmeister M, Gotthardt K, Guerrero-Castillo S, Brandt U.

Biochim Biophys Acta. 2016 Jan;1863(1):91-101. doi: 10.1016/j.bbamcr.2015.10.009. Epub 2015 Oct 23.

35.

Estimating Metabolic Fluxes Using a Maximum Network Flexibility Paradigm.

Megchelenbrink W, Rossell S, Huynen MA, Notebaart RA, Marchiori E.

PLoS One. 2015 Oct 12;10(10):e0139665. doi: 10.1371/journal.pone.0139665. eCollection 2015.

36.

Sequence specificity between interacting and non-interacting homologs identifies interface residues--a homodimer and monomer use case.

Hou Q, Dutilh BE, Huynen MA, Heringa J, Feenstra KA.

BMC Bioinformatics. 2015 Oct 8;16:325. doi: 10.1186/s12859-015-0758-y.

37.

Transcriptome analysis of complex I-deficient patients reveals distinct expression programs for subunits and assembly factors of the oxidative phosphorylation system.

van der Lee R, Szklarczyk R, Smeitink J, Smeets HJ, Huynen MA, Vogel R.

BMC Genomics. 2015 Sep 15;16:691. doi: 10.1186/s12864-015-1883-8.

38.

An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes.

Wheway G, Schmidts M, Mans DA, Szymanska K, Nguyen TT, Racher H, Phelps IG, Toedt G, Kennedy J, Wunderlich KA, Sorusch N, Abdelhamed ZA, Natarajan S, Herridge W, van Reeuwijk J, Horn N, Boldt K, Parry DA, Letteboer SJF, Roosing S, Adams M, Bell SM, Bond J, Higgins J, Morrison EE, Tomlinson DC, Slaats GG, van Dam TJP, Huang L, Kessler K, Giessl A, Logan CV, Boyle EA, Shendure J, Anazi S, Aldahmesh M, Al Hazzaa S, Hegele RA, Ober C, Frosk P, Mhanni AA, Chodirker BN, Chudley AE, Lamont R, Bernier FP, Beaulieu CL, Gordon P, Pon RT, Donahue C, Barkovich AJ, Wolf L, Toomes C, Thiel CT, Boycott KM, McKibbin M, Inglehearn CF; UK10K Consortium; University of Washington Center for Mendelian Genomics, Stewart F, Omran H, Huynen MA, Sergouniotis PI, Alkuraya FS, Parboosingh JS, Innes AM, Willoughby CE, Giles RH, Webster AR, Ueffing M, Blacque O, Gleeson JG, Wolfrum U, Beales PL, Gibson T, Doherty D, Mitchison HM, Roepman R, Johnson CA.

Nat Cell Biol. 2015 Aug;17(8):1074-1087. doi: 10.1038/ncb3201. Epub 2015 Jul 13.

39.

The pros and cons of vertebrate animal models for functional and therapeutic research on inherited retinal dystrophies.

Slijkerman RW, Song F, Astuti GD, Huynen MA, van Wijk E, Stieger K, Collin RW.

Prog Retin Eye Res. 2015 Sep;48:137-59. doi: 10.1016/j.preteyeres.2015.04.004. Epub 2015 May 1. Review.

PMID:
25936606
40.

Predicting human genetic interactions from cancer genome evolution.

Lu X, Megchelenbrink W, Notebaart RA, Huynen MA.

PLoS One. 2015 May 1;10(5):e0125795. doi: 10.1371/journal.pone.0125795. eCollection 2015.

41.

The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections.

Jaeger M, van der Lee R, Cheng SC, Johnson MD, Kumar V, Ng A, Plantinga TS, Smeekens SP, Oosting M, Wang X, Barchet W, Fitzgerald K, Joosten LAB, Perfect JR, Wijmenga C, van de Veerdonk FL, Huynen MA, Xavier RJ, Kullberg BJ, Netea MG.

Eur J Clin Microbiol Infect Dis. 2015 May;34(5):963-974. doi: 10.1007/s10096-014-2309-2. Epub 2015 Jan 13.

42.

Intrinsically disordered segments affect protein half-life in the cell and during evolution.

van der Lee R, Lang B, Kruse K, Gsponer J, Sánchez de Groot N, Huynen MA, Matouschek A, Fuxreiter M, Babu MM.

Cell Rep. 2014 Sep 25;8(6):1832-1844. doi: 10.1016/j.celrep.2014.07.055. Epub 2014 Sep 15.

43.

A mutation in the human CBP4 ortholog UQCC3 impairs complex III assembly, activity and cytochrome b stability.

Wanschers BF, Szklarczyk R, van den Brand MA, Jonckheere A, Suijskens J, Smeets R, Rodenburg RJ, Stephan K, Helland IB, Elkamil A, Rootwelt T, Ott M, van den Heuvel L, Nijtmans LG, Huynen MA.

Hum Mol Genet. 2014 Dec 1;23(23):6356-65. doi: 10.1093/hmg/ddu357. Epub 2014 Jul 9.

PMID:
25008109
44.

MPV17L2 is required for ribosome assembly in mitochondria.

Dalla Rosa I, Durigon R, Pearce SF, Rorbach J, Hirst EM, Vidoni S, Reyes A, Brea-Calvo G, Minczuk M, Woellhaf MW, Herrmann JM, Huynen MA, Holt IJ, Spinazzola A.

Nucleic Acids Res. 2014 Jul;42(13):8500-15. doi: 10.1093/nar/gku513. Epub 2014 Jun 19.

45.

The symbiotic intestinal ciliates and the evolution of their hosts.

Moon-van der Staay SY, van der Staay GW, Michalowski T, Jouany JP, Pristas P, Javorský P, Kišidayová S, Varadyova Z, McEwan NR, Newbold CJ, van Alen T, de Graaf R, Schmid M, Huynen MA, Hackstein JH.

Eur J Protistol. 2014 Apr;50(2):166-73. doi: 10.1016/j.ejop.2014.01.004. Epub 2014 Jan 31.

PMID:
24703617
46.

Mutations in the UQCC1-interacting protein, UQCC2, cause human complex III deficiency associated with perturbed cytochrome b protein expression.

Tucker EJ, Wanschers BF, Szklarczyk R, Mountford HS, Wijeyeratne XW, van den Brand MA, Leenders AM, Rodenburg RJ, Reljić B, Compton AG, Frazier AE, Bruno DL, Christodoulou J, Endo H, Ryan MT, Nijtmans LG, Huynen MA, Thorburn DR.

PLoS Genet. 2013;9(12):e1004034. doi: 10.1371/journal.pgen.1004034. Epub 2013 Dec 26.

47.

Human intellectual disability genes form conserved functional modules in Drosophila.

Oortveld MA, Keerthikumar S, Oti M, Nijhof B, Fernandes AC, Kochinke K, Castells-Nobau A, van Engelen E, Ellenkamp T, Eshuis L, Galy A, van Bokhoven H, Habermann B, Brunner HG, Zweier C, Verstreken P, Huynen MA, Schenck A.

PLoS Genet. 2013 Oct;9(10):e1003911. doi: 10.1371/journal.pgen.1003911. Epub 2013 Oct 31.

48.

Genome evolution predicts genetic interactions in protein complexes and reveals cancer drug targets.

Lu X, Kensche PR, Huynen MA, Notebaart RA.

Nat Commun. 2013;4:2124. doi: 10.1038/ncomms3124.

49.

The SYSCILIA gold standard (SCGSv1) of known ciliary components and its applications within a systems biology consortium.

van Dam TJ, Wheway G, Slaats GG; SYSCILIA Study Group, Huynen MA, Giles RH.

Cilia. 2013 May 31;2(1):7. doi: 10.1186/2046-2530-2-7.

50.

ODoSE: a webserver for genome-wide calculation of adaptive divergence in prokaryotes.

Vos M, te Beek TA, van Driel MA, Huynen MA, Eyre-Walker A, van Passel MW.

PLoS One. 2013 May 6;8(5):e62447. doi: 10.1371/journal.pone.0062447. Print 2013.

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