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Items: 9

1.

Structural basis for substrate selectivity and nucleophilic substitution mechanisms in human adenine phosphoribosyltransferase catalyzed reaction.

Ozeir M, Huyet J, Burgevin MC, Pinson B, Chesney F, Remy JM, Siddiqi AR, Lupoli R, Pinon G, Saint-Marc C, Gibert JF, Morales R, Ceballos-Picot I, Barouki R, Daignan-Fornier B, Olivier-Bandini A, Augé F, Nioche P.

J Biol Chem. 2019 Aug 9;294(32):11980-11991. doi: 10.1074/jbc.RA119.009087. Epub 2019 Jun 3.

2.

Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase.

Huyet J, Ozeir M, Burgevin MC, Pinson B, Chesney F, Remy JM, Siddiqi AR, Lupoli R, Pinon G, Saint-Marc C, Gibert JF, Morales R, Ceballos-Picot I, Barouki R, Daignan-Fornier B, Olivier-Bandini A, Augé F, Nioche P.

Cell Chem Biol. 2018 Jun 21;25(6):666-676.e4. doi: 10.1016/j.chembiol.2018.02.011. Epub 2018 Mar 22.

3.

Clostridium perfringensα-toxin interaction with red cells and model membranes.

Jewell SA, Titball RW, Huyet J, Naylor CE, Basak AK, Gologan P, Winlove CP, Petrov PG.

Soft Matter. 2015 Oct 21;11(39):7748-61. doi: 10.1039/c5sm00876j. Epub 2015 Aug 25.

PMID:
26303814
4.

Structural Insights into Clostridium perfringens Delta Toxin Pore Formation.

Huyet J, Naylor CE, Savva CG, Gibert M, Popoff MR, Basak AK.

PLoS One. 2013 Jun 21;8(6):e66673. doi: 10.1371/journal.pone.0066673. Print 2013.

5.

Structural determinants of ligand binding to the mineralocorticoid receptor.

Huyet J, Pinon GM, Fay MR, Rafestin-Oblin ME, Fagart J.

Mol Cell Endocrinol. 2012 Mar 24;350(2):187-95. doi: 10.1016/j.mce.2011.07.035. Epub 2011 Jul 25. Review.

PMID:
21820032
6.

Crystallization and preliminary X-ray diffraction studies of delta-toxin from Clostridium perfringens.

Huyet J, Gilbert M, Popoff MR, Basak A.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Mar 1;67(Pt 3):369-71. doi: 10.1107/S1744309110054187. Epub 2011 Feb 25.

7.

A new mode of mineralocorticoid receptor antagonism by a potent and selective nonsteroidal molecule.

Fagart J, Hillisch A, Huyet J, Bärfacker L, Fay M, Pleiss U, Pook E, Schäfer S, Rafestin-Oblin ME, Kolkhof P.

J Biol Chem. 2010 Sep 24;285(39):29932-40. doi: 10.1074/jbc.M110.131342. Epub 2010 Jul 22.

8.

Structural basis of spirolactone recognition by the mineralocorticoid receptor.

Huyet J, Pinon GM, Fay MR, Fagart J, Rafestin-Oblin ME.

Mol Pharmacol. 2007 Sep;72(3):563-71. Epub 2007 Jun 14.

PMID:
17569793
9.

Crystal structure of a mutant mineralocorticoid receptor responsible for hypertension.

Fagart J, Huyet J, Pinon GM, Rochel M, Mayer C, Rafestin-Oblin ME.

Nat Struct Mol Biol. 2005 Jun;12(6):554-5. Epub 2005 May 22.

PMID:
15908963

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