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Effectiveness and Safety of Apixaban Compared With Rivaroxaban for Patients With Atrial Fibrillation in Routine Practice: A Cohort Study.

Fralick M, Colacci M, Schneeweiss S, Huybrechts KF, Lin KJ, Gagne JJ.

Ann Intern Med. 2020 Mar 10. doi: 10.7326/M19-2522. [Epub ahead of print]


Validation of algorithms to identify adverse perinatal outcomes in the Medicaid Analytic Extract database.

He M, Huybrechts KF, Dejene SZ, Straub L, Bartels D, Burns S, Combs DJ, Cottral J, Gray KJ, Manning-Geist BL, Mogun H, Reimers RM, Hernandez-Diaz S, Bateman BT.

Pharmacoepidemiol Drug Saf. 2020 Mar 2. doi: 10.1002/pds.4967. [Epub ahead of print]


Maternal and fetal outcomes following exposure to duloxetine in pregnancy: cohort study.

Huybrechts KF, Bateman BT, Pawar A, Bessette LG, Mogun H, Levin R, Li H, Motsko S, Scantamburlo Fernandes MF, Upadhyaya HP, Hernandez-Diaz S.

BMJ. 2020 Feb 19;368:m237. doi: 10.1136/bmj.m237.


Perinatal Outcomes Associated with Maternal Asthma and Its Severity and Control during Pregnancy.

Yland JJ, Bateman BT, Huybrechts KF, Brill G, Schatz MX, Wurst KE, Hernández-Díaz S.

J Allergy Clin Immunol Pract. 2020 Jan 22. pii: S2213-2198(20)30056-8. doi: 10.1016/j.jaip.2020.01.016. [Epub ahead of print]


Safety and Effectiveness of Dabigatran and Other Direct Oral Anticoagulants Compared With Warfarin in Patients With Atrial Fibrillation.

Huybrechts KF, Gopalakrishnan C, Bartels DB, Zint K, Gurusamy VK, Landon J, Schneeweiss S.

Clin Pharmacol Ther. 2019 Dec 23. doi: 10.1002/cpt.1753. [Epub ahead of print]


Using nationally representative survey data for external adjustment of unmeasured confounders: An example using the NHANES data.

Hernández-Díaz S, Bateman BT, Palmsten K, Schneeweiss S, Huybrechts KF.

Pharmacoepidemiol Drug Saf. 2019 Dec 20. doi: 10.1002/pds.4946. [Epub ahead of print]


Evaluating the Utility of Coarsened Exact Matching for Pharmacoepidemiology using Real and Simulated Claims Data.

Ripollone JE, Huybrechts KF, Rothman KJ, Ferguson RE, Franklin JM.

Am J Epidemiol. 2019 Dec 17. pii: kwz268. doi: 10.1093/aje/kwz268. [Epub ahead of print]


Antidiabetic medication use during pregnancy: an international utilization study.

Cesta CE, Cohen JM, Pazzagli L, Bateman BT, Bröms G, Einarsdóttir K, Furu K, Havard A, Heino A, Hernandez-Diaz S, Huybrechts KF, Karlstad Ø, Kieler H, Li J, Leinonen MK, Gulseth HL, Tran D, Yu Y, Zoega H, Odsbu I.

BMJ Open Diabetes Res Care. 2019 Nov 2;7(1):e000759. doi: 10.1136/bmjdrc-2019-000759. eCollection 2019.


Intravenous Ondansetron in Pregnancy and Risk of Congenital Malformations.

Huybrechts KF, Hernandez-Diaz S, Straub L, Gray KJ, Zhu Y, Mogun H, Bateman BT.

JAMA. 2019 Nov 15. doi: 10.1001/jama.2019.18587. [Epub ahead of print] No abstract available.


Identifying pregnancies in insurance claims data: Methods and application to retinoid teratogenic surveillance.

MacDonald SC, Cohen JM, Panchaud A, McElrath TF, Huybrechts KF, Hernández-Díaz S.

Pharmacoepidemiol Drug Saf. 2019 Sep;28(9):1211-1221. doi: 10.1002/pds.4794. Epub 2019 Jul 22.


Poorly Controlled Asthma During Pregnancy Remains Common in the United States.

Cohen JM, Bateman BT, Huybrechts KF, Mogun H, Yland J, Schatz M, Wurst KE, Hernandez-Diaz S.

J Allergy Clin Immunol Pract. 2019 Nov - Dec;7(8):2672-2680.e10. doi: 10.1016/j.jaip.2019.05.043. Epub 2019 Jun 28.


The Impact of Technology on the Diagnosis of Congenital Malformations.

Straub L, Huybrechts KF, Bateman BT, Mogun H, Gray KJ, Holmes LB, Hernandez-Diaz S.

Am J Epidemiol. 2019 Nov 1;188(11):1892-1901. doi: 10.1093/aje/kwz153.


Anticonvulsant Mood Stabilizer and Lithium Use and Risk of Adverse Pregnancy Outcomes.

Cohen JM, Huybrechts KF, Patorno E, Desai RJ, Mogun H, Bateman BT, Hernández-Díaz S.

J Clin Psychiatry. 2019 Jun 18;80(4). pii: 18m12572. doi: 10.4088/JCP.18m12572.


β-Blocker Use in Pregnancy and the Risk for Congenital Malformations.

Bateman BT, Huybrechts KF, Hernandez-Diaz S, Kieler H, Zoega H.

Ann Intern Med. 2019 Jun 18;170(12):909-910. doi: 10.7326/L19-0157. No abstract available.


Use of real-world evidence from healthcare utilization data to evaluate drug safety during pregnancy.

Huybrechts KF, Bateman BT, Hernández-Díaz S.

Pharmacoepidemiol Drug Saf. 2019 Jul;28(7):906-922. doi: 10.1002/pds.4789. Epub 2019 May 10. Review.


Evaluating utilization patterns of oral anticoagulants in routine care.

Gopalakrishnan C, Schneeweiss S, Bartels DB, Zint K, Santiago Ortiz A, Huybrechts KF.

J Thromb Haemost. 2019 Jul;17(7):1033-1043. doi: 10.1111/jth.14467. Epub 2019 May 29.


Antipsychotic utilization patterns among patients with schizophrenic disorder: a cross-national analysis in four countries.

Sultana J, Hurtado I, Bejarano-Quisoboni D, Giorgianni F, Huybrechts KF, Lu Z, Patorno E, Sanfélix-Gimeno G, Tari DU, Trifirò G.

Eur J Clin Pharmacol. 2019 Jul;75(7):1005-1015. doi: 10.1007/s00228-019-02654-9. Epub 2019 Mar 1.


Sequential Monitoring of the Comparative Effectiveness and Safety of Dabigatran in Routine Care.

Schneeweiss S, Gopalakrishnan C, Bartels DB, Franklin JM, Zint K, Kulldorff M, Huybrechts KF.

Circ Cardiovasc Qual Outcomes. 2019 Feb;12(2):e005173. doi: 10.1161/CIRCOUTCOMES.118.005173.


Days' Supply of Initial Opioid Analgesic Prescriptions and Additional Fills for Acute Pain Conditions Treated in the Primary Care Setting - United States, 2014.

Mundkur ML, Franklin JM, Abdia Y, Huybrechts KF, Patorno E, Gagne JJ, Meyer TE, Staffa J, Bateman BT.

MMWR Morb Mortal Wkly Rep. 2019 Feb 15;68(6):140-143. doi: 10.15585/mmwr.mm6806a3.


Association of Maternal First-Trimester Ondansetron Use With Cardiac Malformations and Oral Clefts in Offspring.

Huybrechts KF, Hernández-Díaz S, Straub L, Gray KJ, Zhu Y, Patorno E, Desai RJ, Mogun H, Bateman BT.

JAMA. 2018 Dec 18;320(23):2429-2437. doi: 10.1001/jama.2018.18307.


Claims Data Studies of Direct Oral Anticoagulants Can Achieve Balance in Important Clinical Parameters Only Observable in Electronic Health Records.

Huybrechts KF, Gopalakrishnan C, Franklin JM, Zint K, Franca LR, Bartels DB, Landon J, Schneeweiss S.

Clin Pharmacol Ther. 2019 Apr;105(4):979-993. doi: 10.1002/cpt.1256. Epub 2018 Nov 11.


β-Blocker Use in Pregnancy and the Risk for Congenital Malformations: An International Cohort Study.

Bateman BT, Heide-Jørgensen U, Einarsdóttir K, Engeland A, Furu K, Gissler M, Hernandez-Diaz S, Kieler H, Lahesmaa-Korpinen AM, Mogun H, Nørgaard M, Reutfors J, Selmer R, Huybrechts KF, Zoega H.

Ann Intern Med. 2018 Nov 20;169(10):665-673. doi: 10.7326/M18-0338. Epub 2018 Oct 16.


Opioid dispensing patterns after oocyte retrieval.

Bortoletto P, Prabhu M, Garry EM, Huybrechts KF, Anchan RM, Bateman BT.

Fertil Steril. 2018 Oct;110(5):905-909. doi: 10.1016/j.fertnstert.2018.06.023.


Psychiatric Medications and Reproductive Safety: Scientific and Clinical Perspectives Pertaining to the US FDA Pregnancy and Lactation Labeling Rule.

Freeman MP, Farchione T, Yao L, Sahin L, Taylor L, Huybrechts KF, Nonacs R, Sosinsky AZ, Viguera AC, Cohen LS.

J Clin Psychiatry. 2018 Jul 17;79(4). pii: 18ah38120. doi: 10.4088/JCP.18ah38120.


Longitudinal Trends and Variation in Antipsychotic Use in Older Adults After Cardiac Surgery.

Kim DH, Mahesri M, Bateman BT, Huybrechts KF, Inouye SK, Marcantonio ER, Herzig SJ, Ely EW, Pisani MA, Levin R, Avorn J.

J Am Geriatr Soc. 2018 Aug;66(8):1491-1498. doi: 10.1111/jgs.15418. Epub 2018 Aug 19.


Opioid Overdose After Surgical Discharge.

Ladha KS, Gagne JJ, Patorno E, Huybrechts KF, Rathmell JP, Wang SV, Bateman BT.

JAMA. 2018 Aug 7;320(5):502-504. doi: 10.1001/jama.2018.6933. No abstract available.


Data Mining for Adverse Drug Events With a Propensity Score-matched Tree-based Scan Statistic.

Wang SV, Maro JC, Baro E, Izem R, Dashevsky I, Rogers JR, Nguyen M, Gagne JJ, Patorno E, Huybrechts KF, Major JM, Zhou E, Reidy M, Cosgrove A, Schneeweiss S, Kulldorff M.

Epidemiology. 2018 Nov;29(6):895-903. doi: 10.1097/EDE.0000000000000907.


Frequency of Opioid Dispensing After Vaginal Delivery.

Prabhu M, Garry EM, Hernandez-Diaz S, MacDonald SC, Huybrechts KF, Bateman BT.

Obstet Gynecol. 2018 Aug;132(2):459-465. doi: 10.1097/AOG.0000000000002741.


Changes in Outpatient Use of Antibiotics by Adults in the United States, 2006-2015.

Mundkur ML, Franklin J, Huybrechts KF, Fischer MA, Kesselheim AS, Linder JA, Landon J, Patorno E.

Drug Saf. 2018 Dec;41(12):1333-1342. doi: 10.1007/s40264-018-0697-4.


Anticonvulsants and the risk of perinatal bleeding complications: A pregnancy cohort study.

Panchaud A, Cohen JM, Patorno E, Huybrechts KF, Desai RJ, Gray KJ, Mogun H, Hernandez-Diaz S, Bateman BT.

Neurology. 2018 Aug 7;91(6):e533-e542. doi: 10.1212/WNL.0000000000005944. Epub 2018 Jul 6.


Implications of the Propensity Score Matching Paradox in Pharmacoepidemiology.

Ripollone JE, Huybrechts KF, Rothman KJ, Ferguson RE, Franklin JM.

Am J Epidemiol. 2018 Sep 1;187(9):1951-1961. doi: 10.1093/aje/kwy078.


Continuation of Atypical Antipsychotic Medication During Early Pregnancy and the Risk of Gestational Diabetes.

Park Y, Hernandez-Diaz S, Bateman BT, Cohen JM, Desai RJ, Patorno E, Glynn RJ, Cohen LS, Mogun H, Huybrechts KF.

Am J Psychiatry. 2018 Jun 1;175(6):564-574. doi: 10.1176/appi.ajp.2018.17040393. Epub 2018 May 7.


Using prescription claims to detect aberrant behaviors with opioids: comparison and validation of 5 algorithms.

Rough K, Huybrechts KF, Hernandez-Diaz S, Desai RJ, Patorno E, Bateman BT.

Pharmacoepidemiol Drug Saf. 2019 Jan;28(1):62-69. doi: 10.1002/pds.4443. Epub 2018 Apr 24.


Use of haloperidol versus atypical antipsychotics and risk of in-hospital death in patients with acute myocardial infarction: cohort study.

Park Y, Bateman BT, Kim DH, Hernandez-Diaz S, Patorno E, Glynn RJ, Mogun H, Huybrechts KF.

BMJ. 2018 Mar 28;360:k1218. doi: 10.1136/bmj.k1218.


Generalized boosted modeling to identify subgroups where effect of dabigatran versus warfarin may differ: An observational cohort study of patients with atrial fibrillation.

Wang SV, Huybrechts KF, Fischer MA, Franklin JM, Glynn RJ, Schneeweiss S, Gagne JJ.

Pharmacoepidemiol Drug Saf. 2018 Apr;27(4):383-390. doi: 10.1002/pds.4395. Epub 2018 Jan 30.


Topiramate use early in pregnancy and the risk of oral clefts: A pregnancy cohort study.

Hernandez-Diaz S, Huybrechts KF, Desai RJ, Cohen JM, Mogun H, Pennell PB, Bateman BT, Patorno E.

Neurology. 2018 Jan 23;90(4):e342-e351. doi: 10.1212/WNL.0000000000004857. Epub 2017 Dec 27.


Association Between Methylphenidate and Amphetamine Use in Pregnancy and Risk of Congenital Malformations: A Cohort Study From the International Pregnancy Safety Study Consortium.

Huybrechts KF, Bröms G, Christensen LB, Einarsdóttir K, Engeland A, Furu K, Gissler M, Hernandez-Diaz S, Karlsson P, Karlstad Ø, Kieler H, Lahesmaa-Korpinen AM, Mogun H, Nørgaard M, Reutfors J, Sørensen HT, Zoega H, Bateman BT.

JAMA Psychiatry. 2018 Feb 1;75(2):167-175. doi: 10.1001/jamapsychiatry.2017.3644.


A Bias in the Evaluation of Bias Comparing Randomized Trials with Nonexperimental Studies.

Franklin JM, Dejene S, Huybrechts KF, Wang SV, Kulldorff M, Rothman KJ.

Epidemiol Methods. 2017 Apr;6(1). pii: 20160018. doi: 10.1515/em-2016-0018. Epub 2017 Apr 22.


Placental Complications Associated With Psychostimulant Use in Pregnancy.

Cohen JM, Hernández-Díaz S, Bateman BT, Park Y, Desai RJ, Gray KJ, Patorno E, Mogun H, Huybrechts KF.

Obstet Gynecol. 2017 Dec;130(6):1192-1201. doi: 10.1097/AOG.0000000000002362.


Patterns of opioid initiation at first visits for pain in United States primary care settings.

Mundkur ML, Rough K, Huybrechts KF, Levin R, Gagne JJ, Desai RJ, Patorno E, Choudhry NK, Bateman BT.

Pharmacoepidemiol Drug Saf. 2018 May;27(5):495-503. doi: 10.1002/pds.4322. Epub 2017 Oct 2.


Lithium Use in Pregnancy and the Risk of Cardiac Malformations.

Patorno E, Huybrechts KF, Hernandez-Diaz S.

N Engl J Med. 2017 Aug 31;377(9):893-894. doi: 10.1056/NEJMc1708919. No abstract available.


Risk of neonatal drug withdrawal after intrauterine co-exposure to opioids and psychotropic medications: cohort study.

Huybrechts KF, Bateman BT, Desai RJ, Hernandez-Diaz S, Rough K, Mogun H, Kerzner LS, Davis JM, Stover M, Bartels D, Cottral J, Patorno E.

BMJ. 2017 Aug 2;358:j3326. doi: 10.1136/bmj.j3326.


Variability in the Use of Protective Mechanical Ventilation During General Anesthesia.

Ladha KS, Bateman BT, Houle TT, De Jong MAC, Vidal Melo MF, Huybrechts KF, Kurth T, Eikermann M.

Anesth Analg. 2018 Feb;126(2):503-512. doi: 10.1213/ANE.0000000000002343.


International trends in antipsychotic use: A study in 16 countries, 2005-2014.

Hálfdánarson Ó, Zoëga H, Aagaard L, Bernardo M, Brandt L, Fusté AC, Furu K, Garuoliené K, Hoffmann F, Huybrechts KF, Kalverdijk LJ, Kawakami K, Kieler H, Kinoshita T, Litchfield M, López SC, Machado-Alba JE, Machado-Duque ME, Mahesri M, Nishtala PS, Pearson SA, Reutfors J, Saastamoinen LK, Sato I, Schuiling-Veninga CCM, Shyu YC, Skurtveit S, Verdoux H, Wang LJ, Yahni CZ, Bachmann CJ.

Eur Neuropsychopharmacol. 2017 Oct;27(10):1064-1076. doi: 10.1016/j.euroneuro.2017.07.001. Epub 2017 Jul 27.


Benzodiazepines and risk of all cause mortality in adults: cohort study.

Patorno E, Glynn RJ, Levin R, Lee MP, Huybrechts KF.

BMJ. 2017 Jul 6;358:j2941. doi: 10.1136/bmj.j2941.


Antipsychotic Medication Use Among Publicly Insured Pregnant Women in the United States.

Park Y, Huybrechts KF, Cohen JM, Bateman BT, Desai RJ, Patorno E, Mogun H, Cohen LS, Hernandez-Diaz S.

Psychiatr Serv. 2017 Nov 1;68(11):1112-1119. doi: 10.1176/ Epub 2017 Jun 15.


Patterns of Opioid Prescription and Use After Cesarean Delivery.

Bateman BT, Cole NM, Maeda A, Burns SM, Houle TT, Huybrechts KF, Clancy CR, Hopp SB, Ecker JL, Ende H, Grewe K, Raposo Corradini B, Schoenfeld RE, Sankar K, Day LJ, Harris L, Booth JL, Flood P, Bauer ME, Tsen LC, Landau R, Leffert LR.

Obstet Gynecol. 2017 Jul;130(1):29-35. doi: 10.1097/AOG.0000000000002093.


Lithium Use in Pregnancy and the Risk of Cardiac Malformations.

Patorno E, Huybrechts KF, Bateman BT, Cohen JM, Desai RJ, Mogun H, Cohen LS, Hernandez-Diaz S.

N Engl J Med. 2017 Jun 8;376(23):2245-2254. doi: 10.1056/NEJMoa1612222.


Zidovudine use in pregnancy and congenital malformations.

Rough K, Sun JW, Seage GR 3rd, Williams PL, Huybrechts KF, Bateman BT, Hernandez-Diaz S.

AIDS. 2017 Jul 31;31(12):1733-1743. doi: 10.1097/QAD.0000000000001549. Review.


The Potential Return on Public Investment in Detecting Adverse Drug Effects.

Huybrechts KF, Desai RJ, Park M, Gagne JJ, Najafzadeh M, Avorn J.

Med Care. 2017 Jun;55(6):545-551. doi: 10.1097/MLR.0000000000000717.

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