Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 23

1.

A Proposed Roadmap for Parkinson's Disease Proof of Concept Clinical Trials Investigating Compounds Targeting Alpha-Synuclein.

Merchant KM, Cedarbaum JM, Brundin P, Dave KD, Eberling J, Espay AJ, Hutten SJ, Javidnia M, Luthman J, Maetzler W, Menalled L, Reimer AN, Stoessl AJ, Weiner DM.

J Parkinsons Dis. 2018 Oct 29. doi: 10.3233/JPD-181471. [Epub ahead of print]

PMID:
30400107
2.

Antibody-based methods for the measurement of α-synuclein concentration in human cerebrospinal fluid - method comparison and round robin study.

Mollenhauer B, Bowman FD, Drake D, Duong J, Blennow K, El-Agnaf O, Shaw LM, Masucci J, Taylor P, Umek RM, Dunty JM, Smith CL, Stoops E, Vanderstichele H, Schmid AW, Moniatte M, Zhang J, Kruse N, Lashuel HA, Teunissen C, Schubert T, Dave KD, Hutten SJ, Zetterberg H.

J Neurochem. 2018 Aug 20. doi: 10.1111/jnc.14569. [Epub ahead of print]

PMID:
30125936
3.

CRISPR-enhanced engineering of therapy-sensitive cancer cells for self-targeting of primary and metastatic tumors.

Reinshagen C, Bhere D, Choi SH, Hutten S, Nesterenko I, Wakimoto H, Le Roux E, Rizvi A, Du W, Minicucci C, Shah K.

Sci Transl Med. 2018 Jul 11;10(449). pii: eaao3240. doi: 10.1126/scitranslmed.aao3240.

PMID:
29997250
4.

Nuclear egress of TDP-43 and FUS occurs independently of Exportin-1/CRM1.

Ederle H, Funk C, Abou-Ajram C, Hutten S, Funk EBE, Kehlenbach RH, Bailer SM, Dormann D.

Sci Rep. 2018 May 4;8(1):7084. doi: 10.1038/s41598-018-25007-5.

5.

Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.

Hofweber M, Hutten S, Bourgeois B, Spreitzer E, Niedner-Boblenz A, Schifferer M, Ruepp MD, Simons M, Niessing D, Madl T, Dormann D.

Cell. 2018 Apr 19;173(3):706-719.e13. doi: 10.1016/j.cell.2018.03.004.

PMID:
29677514
6.

A user's guide for α-synuclein biomarker studies in biological fluids: Perianalytical considerations.

Mollenhauer B, Batrla R, El-Agnaf O, Galasko DR, Lashuel HA, Merchant KM, Shaw LM, Selkoe DJ, Umek R, Vanderstichele H, Zetterberg H, Zhang J, Caspell-Garcia C, Coffey C, Hutten SJ, Frasier M, Taylor P; Investigating Synuclein Consortium of the Michael J. Fox Foundation for Parkinson's Research.

Mov Disord. 2017 Aug;32(8):1117-1130. doi: 10.1002/mds.27090. Epub 2017 Jul 22. Review.

7.

Dexamethasone-conjugated DNA nanotubes as anti-inflammatory agents in vivo.

Sellner S, Kocabey S, Zhang T, Nekolla K, Hutten S, Krombach F, Liedl T, Rehberg M.

Biomaterials. 2017 Jul;134:78-90. doi: 10.1016/j.biomaterials.2017.04.031. Epub 2017 Apr 17.

PMID:
28458030
8.

Visualization of BRI1 and SERK3/BAK1 Nanoclusters in Arabidopsis Roots.

Hutten SJ, Hamers DS, Aan den Toorn M, van Esse W, Nolles A, Bücherl CA, de Vries SC, Hohlbein J, Borst JW.

PLoS One. 2017 Jan 23;12(1):e0169905. doi: 10.1371/journal.pone.0169905. eCollection 2017.

9.

The Search for a Peripheral Biopsy Indicator of α-Synuclein Pathology for Parkinson Disease.

Lee JM, Derkinderen P, Kordower JH, Freeman R, Munoz DG, Kremer T, Zago W, Hutten SJ, Adler CH, Serrano GE, Beach TG.

J Neuropathol Exp Neurol. 2017 Jan 1;76(1):2-15. doi: 10.1093/jnen/nlw103. Review.

PMID:
28069931
10.

hnRNPA2/B1 Function in Neurodegeneration: It's a Gain, Not a Loss.

Hutten S, Dormann D.

Neuron. 2016 Nov 23;92(4):672-674. doi: 10.1016/j.neuron.2016.11.014.

11.

Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study.

Nalls MA, McLean CY, Rick J, Eberly S, Hutten SJ, Gwinn K, Sutherland M, Martinez M, Heutink P, Williams NM, Hardy J, Gasser T, Brice A, Price TR, Nicolas A, Keller MF, Molony C, Gibbs JR, Chen-Plotkin A, Suh E, Letson C, Fiandaca MS, Mapstone M, Federoff HJ, Noyce AJ, Morris H, Van Deerlin VM, Weintraub D, Zabetian C, Hernandez DG, Lesage S, Mullins M, Conley ED, Northover CA, Frasier M, Marek K, Day-Williams AG, Stone DJ, Ioannidis JP, Singleton AB; Parkinson's Disease Biomarkers Program and Parkinson's Progression Marker Initiative investigators.

Lancet Neurol. 2015 Oct;14(10):1002-9. doi: 10.1016/S1474-4422(15)00178-7. Epub 2015 Aug 10.

12.

Time-lapse imaging of nuclear bodies.

Hutten S, Swift S, Lamond AI.

Methods Mol Biol. 2015;1262:55-67. doi: 10.1007/978-1-4939-2253-6_4.

PMID:
25555575
13.

Unmasking the messenger.

Hutten S, Sharangdhar T, Kiebler M.

RNA Biol. 2014;11(8):992-7. doi: 10.4161/rna.32091. Epub 2014 Oct 31. Review.

14.

Importin 7 and Nup358 promote nuclear import of the protein component of human telomerase.

Frohnert C, Hutten S, Wälde S, Nath A, Kehlenbach RH.

PLoS One. 2014 Feb 20;9(2):e88887. doi: 10.1371/journal.pone.0088887. eCollection 2014.

15.

A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II.

Hutten S, Chachami G, Winter U, Melchior F, Lamond AI.

J Cell Sci. 2014 Mar 1;127(Pt 5):1065-78. doi: 10.1242/jcs.141788. Epub 2014 Jan 10.

16.

The nucleoporin Nup358/RanBP2 promotes nuclear import in a cargo- and transport receptor-specific manner.

Wälde S, Thakar K, Hutten S, Spillner C, Nath A, Rothbauer U, Wiemann S, Kehlenbach RH.

Traffic. 2012 Feb;13(2):218-33. doi: 10.1111/j.1600-0854.2011.01302.x. Epub 2011 Nov 21.

17.

An intranucleolar body associated with rDNA.

Hutten S, Prescott A, James J, Riesenberg S, Boulon S, Lam YW, Lamond AI.

Chromosoma. 2011 Oct;120(5):481-99. doi: 10.1007/s00412-011-0327-8. Epub 2011 Jun 23.

18.

The nucleolus under stress.

Boulon S, Westman BJ, Hutten S, Boisvert FM, Lamond AI.

Mol Cell. 2010 Oct 22;40(2):216-27. doi: 10.1016/j.molcel.2010.09.024. Review.

19.

A proteomic screen for nucleolar SUMO targets shows SUMOylation modulates the function of Nop5/Nop58.

Westman BJ, Verheggen C, Hutten S, Lam YW, Bertrand E, Lamond AI.

Mol Cell. 2010 Aug 27;39(4):618-31. doi: 10.1016/j.molcel.2010.07.025.

20.

The nuclear pore component Nup358 promotes transportin-dependent nuclear import.

Hutten S, Wälde S, Spillner C, Hauber J, Kehlenbach RH.

J Cell Sci. 2009 Apr 15;122(Pt 8):1100-10. doi: 10.1242/jcs.040154. Epub 2009 Mar 19.

21.

The Nup358-RanGAP complex is required for efficient importin alpha/beta-dependent nuclear import.

Hutten S, Flotho A, Melchior F, Kehlenbach RH.

Mol Biol Cell. 2008 May;19(5):2300-10. doi: 10.1091/mbc.E07-12-1279. Epub 2008 Feb 27.

22.

CRM1-mediated nuclear export: to the pore and beyond.

Hutten S, Kehlenbach RH.

Trends Cell Biol. 2007 Apr;17(4):193-201. Epub 2007 Feb 20.

PMID:
17317185
23.

Nup214 is required for CRM1-dependent nuclear protein export in vivo.

Hutten S, Kehlenbach RH.

Mol Cell Biol. 2006 Sep;26(18):6772-85.

Supplemental Content

Loading ...
Support Center