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Items: 35

1.

Preclinical efficacy and safety of KCNH2-G628S gene therapy for postoperative atrial fibrillation.

Liu Z, Hutt JA, Rajeshkumar B, Azuma Y, Duan KL, Donahue JK.

J Thorac Cardiovasc Surg. 2017 Nov;154(5):1644-1651.e8. doi: 10.1016/j.jtcvs.2017.05.052. Epub 2017 May 23.

2.

The Natural History of Pneumonic Tularemia in Female Fischer 344 Rats after Inhalational Exposure to Aerosolized Francisella tularensis Subspecies tularensis Strain SCHU S4.

Hutt JA, Lovchik JA, Dekonenko A, Hahn AC, Wu TH.

Am J Pathol. 2017 Feb;187(2):252-267. doi: 10.1016/j.ajpath.2016.09.021. Epub 2016 Dec 8.

3.

Safety and biodistribution assessment of sc-rAAV2.5IL-1Ra administered via intra-articular injection in a mono-iodoacetate-induced osteoarthritis rat model.

Wang G, Evans CH, Benson JM, Hutt JA, Seagrave J, Wilder JA, Grieger JC, Samulski RJ, Terse PS.

Mol Ther Methods Clin Dev. 2016 Jan 13;3:15052. doi: 10.1038/mtm.2015.52. eCollection 2016.

4.

Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection.

Reed MD, Wilder JA, Mega WM, Hutt JA, Kuehl PJ, Valderas MW, Chew LL, Liang BC, Squires CH.

PLoS One. 2015 Jul 24;10(7):e0130952. doi: 10.1371/journal.pone.0130952. eCollection 2015.

5.

Lethal factor, but not edema factor, is required to cause fatal anthrax in cynomolgus macaques after pulmonary spore challenge.

Hutt JA, Lovchik JA, Drysdale M, Sherwood RL, Brasel T, Lipscomb MF, Lyons CR.

Am J Pathol. 2014 Dec;184(12):3205-16. doi: 10.1016/j.ajpath.2014.08.008. Epub 2014 Oct 5.

6.

Local and systemic tolerability of a 2'O-methoxyethyl antisense oligonucleotide targeting interleukin-4 receptor-α delivery by inhalation in mouse and monkey.

Fey RA, Templin MV, McDonald JD, Yu RZ, Hutt JA, Gigliotti AP, Henry SP, Reed MD.

Inhal Toxicol. 2014 Jul;26(8):452-63. doi: 10.3109/08958378.2014.907587. Epub 2014 Jun 16.

PMID:
24932560
7.

Intrapleural administration of an AAVrh.10 vector coding for human α1-antitrypsin for the treatment of α1-antitrypsin deficiency.

Chiuchiolo MJ, Kaminsky SM, Sondhi D, Hackett NR, Rosenberg JB, Frenk EZ, Hwang Y, Van de Graaf BG, Hutt JA, Wang G, Benson J, Crystal RG.

Hum Gene Ther Clin Dev. 2013 Dec;24(4):161-73. doi: 10.1089/humc.2013.168.

PMID:
24191907
8.

Expression of either lethal toxin or edema toxin by Bacillus anthracis is sufficient for virulence in a rabbit model of inhalational anthrax.

Lovchik JA, Drysdale M, Koehler TM, Hutt JA, Lyons CR.

Infect Immun. 2012 Jul;80(7):2414-25. doi: 10.1128/IAI.06340-11. Epub 2012 Apr 23.

9.

Cowpox virus inhibits human dendritic cell immune function by nonlethal, nonproductive infection.

Hansen SJ, Rushton J, Dekonenko A, Chand HS, Olson GK, Hutt JA, Pickup D, Lyons CR, Lipscomb MF.

Virology. 2011 Apr 10;412(2):411-25. doi: 10.1016/j.virol.2011.01.024. Epub 2011 Feb 21.

10.

Antibodies contribute to effective vaccination against respiratory infection by type A Francisella tularensis strains.

Mara-Koosham G, Hutt JA, Lyons CR, Wu TH.

Infect Immun. 2011 Apr;79(4):1770-8. doi: 10.1128/IAI.00605-10. Epub 2011 Jan 31.

11.

Zebrafish atlastin controls motility and spinal motor axon architecture via inhibition of the BMP pathway.

Fassier C, Hutt JA, Scholpp S, Lumsden A, Giros B, Nothias F, Schneider-Maunoury S, Houart C, Hazan J.

Nat Neurosci. 2010 Nov;13(11):1380-7. doi: 10.1038/nn.2662. Epub 2010 Oct 10.

PMID:
20935645
12.

Preclinical evaluation of a recombinant adeno-associated virus vector expressing human alpha-1 antitrypsin made using a recombinant herpes simplex virus production method.

Chulay JD, Ye GJ, Thomas DL, Knop DR, Benson JM, Hutt JA, Wang G, Humphries M, Flotte TR.

Hum Gene Ther. 2011 Feb;22(2):155-65. doi: 10.1089/hum.2010.118. Epub 2010 Dec 12.

13.

Aerobiology and inhalation exposure to biological select agents and toxins.

Roy CJ, Reed DS, Hutt JA.

Vet Pathol. 2010 Sep;47(5):779-89. doi: 10.1177/0300985810378650. Epub 2010 Aug 3. Review.

PMID:
20682804
14.

Granuloma formation induced by low-dose chronic silica inhalation is associated with an anti-apoptotic response in Lewis rats.

Langley RJ, Mishra NC, Peña-Philippides JC, Hutt JA, Sopori ML.

J Toxicol Environ Health A. 2010;73(10):669-83. doi: 10.1080/15287390903578521.

15.

Vaccination of Fischer 344 rats against pulmonary infections by Francisella tularensis type A strains.

Wu TH, Zsemlye JL, Statom GL, Hutt JA, Schrader RM, Scrymgeour AA, Lyons CR.

Vaccine. 2009 Jul 23;27(34):4684-93. doi: 10.1016/j.vaccine.2009.05.060. Epub 2009 Jun 9.

16.

The SARS-CoV ferret model in an infection-challenge study.

Chu YK, Ali GD, Jia F, Li Q, Kelvin D, Couch RC, Harrod KS, Hutt JA, Cameron C, Weiss SR, Jonsson CB.

Virology. 2008 Apr 25;374(1):151-63. doi: 10.1016/j.virol.2007.12.032. Epub 2008 Jan 29.

17.

A review of the histopathology of cigarette smoke-induced lung cancer in rats and mice.

Hahn FF, Gigliotti AP, Hutt JA, March TH, Mauderly JL.

Int J Toxicol. 2007 Jul-Aug;26(4):307-13.

PMID:
17661221
18.

Comparative oncology of lung tumors.

Hahn FF, Gigliotti A, Hutt JA.

Toxicol Pathol. 2007 Jan;35(1):130-5. Erratum in: Toxicol Pathol. 2007;35(3):458.

PMID:
17325981
19.

C-reactive protein-mediated suppression of nephrotoxic nephritis: role of macrophages, complement, and Fcgamma receptors.

Rodriguez W, Mold C, Kataranovski M, Hutt JA, Marnell LL, Verbeek JS, Du Clos TW.

J Immunol. 2007 Jan 1;178(1):530-8.

20.

The homeodomain transcription factor drg11 is expressed in primary sensory neurons and their putative CNS targets during embryonic development of the zebrafish.

McCormick LJ, Hutt JA, Hazan J, Houart C, Cohen J.

Gene Expr Patterns. 2007 Jan;7(3):289-96. Epub 2006 Sep 9.

PMID:
17045851
21.

Gene promoter hypermethylation in mouse lung tumors.

Vuillemenot BR, Hutt JA, Belinsky SA.

Mol Cancer Res. 2006 Apr;4(4):267-73.

22.

Cigarette smoke suppresses Th1 cytokine production and increases RSV expression in a neonatal model.

Phaybouth V, Wang SZ, Hutt JA, McDonald JD, Harrod KS, Barrett EG.

Am J Physiol Lung Cell Mol Physiol. 2006 Feb;290(2):L222-31. Epub 2005 Aug 26.

23.

Molecular evidence from Ciona intestinalis for the evolutionary origin of vertebrate sensory placodes.

Mazet F, Hutt JA, Milloz J, Millard J, Graham A, Shimeld SM.

Dev Biol. 2005 Jun 15;282(2):494-508.

24.

Life-span inhalation exposure to mainstream cigarette smoke induces lung cancer in B6C3F1 mice through genetic and epigenetic pathways.

Hutt JA, Vuillemenot BR, Barr EB, Grimes MJ, Hahn FF, Hobbs CH, March TH, Gigliotti AP, Seilkop SK, Finch GL, Mauderly JL, Belinsky SA.

Carcinogenesis. 2005 Nov;26(11):1999-2009. Epub 2005 Jun 8. Erratum in: Carcinogenesis. 2005 Dec;26(12):2214.

PMID:
15944214
25.

Intranasal vaccination induces protective immunity against intranasal infection with virulent Francisella tularensis biovar A.

Wu TH, Hutt JA, Garrison KA, Berliba LS, Zhou Y, Lyons CR.

Infect Immun. 2005 May;73(5):2644-54.

26.

The toxicity of microcystin LR in mice following 7 days of inhalation exposure.

Benson JM, Hutt JA, Rein K, Boggs SE, Barr EB, Fleming LE.

Toxicon. 2005 May;45(6):691-8.

27.
28.

Carcinogen exposure differentially modulates RAR-beta promoter hypermethylation, an early and frequent event in mouse lung carcinogenesis.

Vuillemenot BR, Pulling LC, Palmisano WA, Hutt JA, Belinsky SA.

Carcinogenesis. 2004 Apr;25(4):623-9. Epub 2003 Dec 4.

PMID:
14656941
29.

Pax gene expression in the developing central nervous system of Ciona intestinalis.

Mazet F, Hutt JA, Millard J, Shimeld SM.

Gene Expr Patterns. 2003 Dec;3(6):743-5.

PMID:
14643682
32.

Transcriptional regulation of C/EBPdelta in G(0) growth-arrested mouse mammary epithelial cells.

O'Rourke JP, Hutt JA, DeWille J.

Biochem Biophys Res Commun. 1999 Sep 7;262(3):696-701.

PMID:
10471388
33.

CCAAT/enhancer-binding protein delta regulates mammary epithelial cell G0 growth arrest and apoptosis.

O'Rourke JP, Newbound GC, Hutt JA, DeWille J.

J Biol Chem. 1999 Jun 4;274(23):16582-9.

34.

Thoracic and abdominal blastomycosis in a horse.

Toribio RE, Kohn CW, Lawrence AE, Hardy J, Hutt JA.

J Am Vet Med Assoc. 1999 May 1;214(9):1357-60, 1335.

PMID:
10319179
35.

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