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Items: 1 to 50 of 315

1.

Histomorphometric analysis of critical-sized bone defects using Osteomeasure and Aperio systems.

Medeiros Savi F, Lawrence F, Hutmacher DW, Woodruff M, Bray LJ, Wille ML.

Tissue Eng Part C Methods. 2019 Oct 30. doi: 10.1089/ten.TEC.2019.0179. [Epub ahead of print]

PMID:
31663423
2.

Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of zoledronic acid in vivo.

Landgraf M, Lahr CA, Sanchez-Herrero A, Meinert C, Shokoohmand A, Pollock PM, Hutmacher DW, Shafiee A, McGovern JA.

Bone Res. 2019 Oct 21;7:31. doi: 10.1038/s41413-019-0072-9. eCollection 2019.

3.

Addressing Patient Specificity in the Engineering of Tumor Models.

Bray LJ, Hutmacher DW, Bock N.

Front Bioeng Biotechnol. 2019 Sep 12;7:217. doi: 10.3389/fbioe.2019.00217. eCollection 2019. Review.

4.

Investigation of Sustained BMP Delivery in the Prevention of Medication-Related Osteonecrosis of the Jaw (MRONJ) in a Rat Model.

Brierly GI, Ren J, Baldwin J, Saifzadeh S, Theodoropoulos C, Tsurkan MV, Lynham A, Hsu E, Nikolarakos D, Werner C, Woodruff MA, Hutmacher DW, Bray LJ.

Macromol Biosci. 2019 Nov;19(11):e1900226. doi: 10.1002/mabi.201900226. Epub 2019 Sep 24.

PMID:
31549786
5.

Microenvironment engineering of osteoblastic bone metastases reveals osteomimicry of patient-derived prostate cancer xenografts.

Shokoohmand A, Ren J, Baldwin J, Atack A, Shafiee A, Theodoropoulos C, Wille ML, Tran PA, Bray LJ, Smith D, Chetty N, Pollock PM, Hutmacher DW, Clements JA, Williams ED, Bock N.

Biomaterials. 2019 Nov;220:119402. doi: 10.1016/j.biomaterials.2019.119402. Epub 2019 Jul 31.

PMID:
31400612
6.

In vitro disease models 4.0 via automation and high-throughput processing.

Eggert S, Hutmacher DW.

Biofabrication. 2019 Jul 11;11(4):043002. doi: 10.1088/1758-5090/ab296f.

PMID:
31293247
7.

Recombinant Human Bone Morphogenetic Protein 7 Exerts Osteo-Catabolic Effects on Bone Grafts That Outweigh Its Osteo-Anabolic Capacity.

Lahr CA, Wagner F, Shafiee A, Rudert M, Hutmacher DW, Holzapfel BM.

Calcif Tissue Int. 2019 Sep;105(3):331-340. doi: 10.1007/s00223-019-00574-5. Epub 2019 Jun 18.

PMID:
31214730
8.

Immunogold FIB-SEM: Combining Volumetric Ultrastructure Visualization with 3D Biomolecular Analysis to Dissect Cell-Environment Interactions.

Gopal S, Chiappini C, Armstrong JPK, Chen Q, Serio A, Hsu CC, Meinert C, Klein TJ, Hutmacher DW, Rothery S, Stevens MM.

Adv Mater. 2019 Aug;31(32):e1900488. doi: 10.1002/adma.201900488. Epub 2019 Jun 13.

9.

Biologically Inspired Scaffolds for Heart Valve Tissue Engineering via Melt Electrowriting.

Saidy NT, Wolf F, Bas O, Keijdener H, Hutmacher DW, Mela P, De-Juan-Pardo EM.

Small. 2019 Jun;15(24):e1900873. doi: 10.1002/smll.201900873. Epub 2019 May 6.

PMID:
31058444
10.

Engineering osteoblastic metastases to delineate the adaptive response of androgen-deprived prostate cancer in the bone metastatic microenvironment.

Bock N, Shokoohmand A, Kryza T, Röhl J, Meijer J, Tran PA, Nelson CC, Clements JA, Hutmacher DW.

Bone Res. 2019 Apr 25;7:13. doi: 10.1038/s41413-019-0049-8. eCollection 2019.

11.

A clarion call for understanding regulatory processes for additive manufacturing in the health sector.

Horst A, McDonald F, Hutmacher DW.

Expert Rev Med Devices. 2019 May;16(5):405-412. doi: 10.1080/17434440.2019.1609353. Epub 2019 Apr 30. Review.

PMID:
31037978
12.

Periodontal Tissue Engineering with a Multiphasic Construct and Cell Sheets.

Vaquette C, Saifzadeh S, Farag A, Hutmacher DW, Ivanovski S.

J Dent Res. 2019 Jun;98(6):673-681. doi: 10.1177/0022034519837967. Epub 2019 Apr 10.

PMID:
30971166
13.

3D printed dual macro-, microscale porous network as a tissue engineering scaffold with drug delivering function.

Dang HP, Shabab T, Shafiee A, Peiffer QC, Fox K, Tran N, Dargaville TR, Hutmacher DW, Tran PA.

Biofabrication. 2019 Apr 26;11(3):035014. doi: 10.1088/1758-5090/ab14ff.

PMID:
30933941
14.

A humanized bone microenvironment uncovers HIF2 alpha as a latent marker for osteosarcoma.

Wagner F, Holzapfel BM, Martine LC, McGovern J, Lahr CA, Boxberg M, Prodinger PM, Grässel S, Loessner D, Hutmacher DW.

Acta Biomater. 2019 Apr 15;89:372-381. doi: 10.1016/j.actbio.2019.02.051. Epub 2019 Mar 2.

PMID:
30836200
15.

Radium 223-Mediated Zonal Cytotoxicity of Prostate Cancer in Bone.

Dondossola E, Casarin S, Paindelli C, De-Juan-Pardo EM, Hutmacher DW, Logothetis CJ, Friedl P.

J Natl Cancer Inst. 2019 Oct 1;111(10):1042-1050. doi: 10.1093/jnci/djz007.

PMID:
30657953
16.

Tuning mechanical reinforcement and bioactivity of 3D printed ternary nanocomposites by interfacial peptide-polymer conjugates.

Bas O, Hanßke F, Lim J, Ravichandran A, Kemnitz E, Teoh SH, Hutmacher DW, Börner HG.

Biofabrication. 2019 Jun 12;11(3):035028. doi: 10.1088/1758-5090/aafec8.

PMID:
30645987
17.

Tissue engineered human prostate microtissues reveal key role of mast cell-derived tryptase in potentiating cancer-associated fibroblast (CAF)-induced morphometric transition in vitro.

Pereira BA, Lister NL, Hashimoto K, Teng L, Flandes-Iparraguirre M, Eder A, Sanchez-Herrero A, Niranjan B; Melbourne Urological Research Alliance (MURAL).

Biomaterials. 2019 Mar;197:72-85. doi: 10.1016/j.biomaterials.2018.12.030. Epub 2019 Jan 2.

PMID:
30641266
18.

Printomics: the high-throughput analysis of printing parameters applied to melt electrowriting.

Wunner FM, Mieszczanek P, Bas O, Eggert S, Maartens J, Dalton PD, De-Juan-Pardo EM, Hutmacher DW.

Biofabrication. 2019 Jan 24;11(2):025004. doi: 10.1088/1758-5090/aafc41.

PMID:
30616231
19.

Humanization of the Prostate Microenvironment Reduces Homing of PC3 Prostate Cancer Cells to Human Tissue-Engineered Bone.

McGovern JA, Shafiee A, Wagner F, Lahr CA, Landgraf M, Meinert C, Williams ED, Russell PJ, Clements JA, Loessner D, Holzapfel BM, Risbridger GP, Hutmacher DW.

Cancers (Basel). 2018 Nov 13;10(11). pii: E438. doi: 10.3390/cancers10110438.

20.

A 3D tumor microenvironment regulates cell proliferation, peritoneal growth and expression patterns.

Loessner D, Rockstroh A, Shokoohmand A, Holzapfel BM, Wagner F, Baldwin J, Boxberg M, Schmalfeldt B, Lengyel E, Clements JA, Hutmacher DW.

Biomaterials. 2019 Jan;190-191:63-75. doi: 10.1016/j.biomaterials.2018.10.014. Epub 2018 Oct 16.

PMID:
30396040
21.

Nipple Reconstruction: A Regenerative Medicine Approach Using 3D-Printed Tissue Scaffolds.

Khoo D, Ung O, Blomberger D, Hutmacher DW.

Tissue Eng Part B Rev. 2019 Apr;25(2):126-134. doi: 10.1089/ten.TEB.2018.0253. Review.

PMID:
30379123
22.

Engineering Anisotropic Muscle Tissue using Acoustic Cell Patterning.

Armstrong JPK, Puetzer JL, Serio A, Guex AG, Kapnisi M, Breant A, Zong Y, Assal V, Skaalure SC, King O, Murty T, Meinert C, Franklin AC, Bassindale PG, Nichols MK, Terracciano CM, Hutmacher DW, Drinkwater BW, Klein TJ, Perriman AW, Stevens MM.

Adv Mater. 2018 Oct;30(43):e1802649. doi: 10.1002/adma.201802649. Epub 2018 Sep 12.

23.

Tissue Engineered Constructs for Periodontal Regeneration: Current Status and Future Perspectives.

Vaquette C, Pilipchuk SP, Bartold PM, Hutmacher DW, Giannobile WV, Ivanovski S.

Adv Healthc Mater. 2018 Nov;7(21):e1800457. doi: 10.1002/adhm.201800457. Epub 2018 Aug 26. Review.

PMID:
30146758
24.

Intravital microscopy of osteolytic progression and therapy response of cancer lesions in the bone.

Dondossola E, Alexander S, Holzapfel BM, Filippini S, Starbuck MW, Hoffman RM, Navone N, De-Juan-Pardo EM, Logothetis CJ, Hutmacher DW, Friedl P.

Sci Transl Med. 2018 Aug 1;10(452). pii: eaao5726. doi: 10.1126/scitranslmed.aao5726.

25.

The quest for mechanically and biologically functional soft biomaterials via soft network composites.

Bas O, Catelas I, De-Juan-Pardo EM, Hutmacher DW.

Adv Drug Deliv Rev. 2018 Jul;132:214-234. doi: 10.1016/j.addr.2018.07.015. Epub 2018 Jul 24. Review.

PMID:
30048654
26.

SpheroidSim-Preliminary evaluation of a new computational tool to predict the influence of cell cycle time and phase fraction on spheroid growth.

Little JP, Pettet GJ, Hutmacher DW, Loessner D.

Biotechnol Prog. 2018 Nov;34(6):1335-1343. doi: 10.1002/btpr.2692. Epub 2018 Sep 11.

PMID:
30009492
27.

Non-linear optical microscopy and histological analysis of collagen, elastin and lysyl oxidase expression in breast capsular contracture.

Poh PSP, Schmauss V, McGovern JA, Schmauss D, Chhaya MP, Foehr P, Seeger M, Ntziachristos V, Hutmacher DW, van Griensven M, Schantz JT, Balmayor ER.

Eur J Med Res. 2018 Jun 4;23(1):30. doi: 10.1186/s40001-018-0322-0.

28.

A Method for Prostate and Breast Cancer Cell Spheroid Cultures Using Gelatin Methacryloyl-Based Hydrogels.

Meinert C, Theodoropoulos C, Klein TJ, Hutmacher DW, Loessner D.

Methods Mol Biol. 2018;1786:175-194. doi: 10.1007/978-1-4939-7845-8_10.

PMID:
29786793
29.

Humanization of bone and bone marrow in an orthotopic site reveals new potential therapeutic targets in osteosarcoma.

Wagner F, Holzapfel BM, McGovern JA, Shafiee A, Baldwin JG, Martine LC, Lahr CA, Wunner FM, Friis T, Bas O, Boxberg M, Prodinger PM, Shokoohmand A, Moi D, Mazzieri R, Loessner D, Hutmacher DW.

Biomaterials. 2018 Jul;171:230-246. doi: 10.1016/j.biomaterials.2018.04.030. Epub 2018 Apr 16.

PMID:
29705656
30.

Animal models for bone tissue engineering and modelling disease.

McGovern JA, Griffin M, Hutmacher DW.

Dis Model Mech. 2018 Apr 23;11(4). pii: dmm033084. doi: 10.1242/dmm.033084. Review.

31.

Immune system augmentation via humanization using stem/progenitor cells and bioengineering in a breast cancer model study.

Shafiee A, McGovern JA, Lahr CA, Meinert C, Moi D, Wagner F, Landgraf M, De-Juan-Pardo E, Mazzieri R, Hutmacher DW.

Int J Cancer. 2018 Sep 15;143(6):1470-1482. doi: 10.1002/ijc.31528. Epub 2018 May 7.

32.

Melt Electrospinning Writing of Highly Ordered Large Volume Scaffold Architectures.

Wunner FM, Wille ML, Noonan TG, Bas O, Dalton PD, De-Juan-Pardo EM, Hutmacher DW.

Adv Mater. 2018 May;30(20):e1706570. doi: 10.1002/adma.201706570. Epub 2018 Apr 10.

PMID:
29633443
33.

3D printed Polycaprolactone scaffolds with dual macro-microporosity for applications in local delivery of antibiotics.

Visscher LE, Dang HP, Knackstedt MA, Hutmacher DW, Tran PA.

Mater Sci Eng C Mater Biol Appl. 2018 Jun 1;87:78-89. doi: 10.1016/j.msec.2018.02.008. Epub 2018 Feb 15.

PMID:
29549952
34.

The effect of decellularized tissue engineered constructs on periodontal regeneration.

Farag A, Hashimi SM, Vaquette C, Bartold PM, Hutmacher DW, Ivanovski S.

J Clin Periodontol. 2018 May;45(5):586-596. doi: 10.1111/jcpe.12886. Epub 2018 Apr 17.

PMID:
29500836
35.

Meso-Endothelial Bipotent Progenitors from Human Placenta Display Distinct Molecular and Cellular Identity.

Shafiee A, Patel J, Hutmacher DW, Fisk NM, Khosrotehrani K.

Stem Cell Reports. 2018 Mar 13;10(3):890-904. doi: 10.1016/j.stemcr.2018.01.011. Epub 2018 Mar 1.

36.

Assessment of static and perfusion methods for decellularization of PCL membrane-supported periodontal ligament cell sheet constructs.

Farag A, Hashimi SM, Vaquette C, Volpato FZ, Hutmacher DW, Ivanovski S.

Arch Oral Biol. 2018 Apr;88:67-76. doi: 10.1016/j.archoralbio.2018.01.014. Epub 2018 Jan 31.

PMID:
29407754
37.

Melt Electrospinning Writing of Three-dimensional Poly(ε-caprolactone) Scaffolds with Controllable Morphologies for Tissue Engineering Applications.

Wunner FM, Bas O, Saidy NT, Dalton PD, Pardo EMD, Hutmacher DW.

J Vis Exp. 2017 Dec 23;(130). doi: 10.3791/56289.

PMID:
29364204
38.

Rational Design of Mouse Models for Cancer Research.

Landgraf M, McGovern JA, Friedl P, Hutmacher DW.

Trends Biotechnol. 2018 Mar;36(3):242-251. doi: 10.1016/j.tibtech.2017.12.001. Epub 2018 Jan 5. Review.

PMID:
29310843
39.

Independent Evaluation of Medical-Grade Bioresorbable Filaments for Fused Deposition Modelling/Fused Filament Fabrication of Tissue Engineered Constructs.

Mohseni M, Hutmacher DW, Castro NJ.

Polymers (Basel). 2018 Jan 2;10(1). pii: E40. doi: 10.3390/polym10010040.

40.

A novel bioreactor system for biaxial mechanical loading enhances the properties of tissue-engineered human cartilage.

Meinert C, Schrobback K, Hutmacher DW, Klein TJ.

Sci Rep. 2017 Dec 5;7(1):16997. doi: 10.1038/s41598-017-16523-x.

41.

A Novel 3D Cultured Model for Studying Early Changes in Age-Related Macular Degeneration.

Shokoohmand A, Jeon JE, Theodoropoulos C, Baldwin JG, Hutmacher DW, Feigl B.

Macromol Biosci. 2017 Dec;17(12). doi: 10.1002/mabi.201700221. Epub 2017 Oct 27.

PMID:
29076662
42.

Mesenchymal stem/stromal cells enhance engraftment, vasculogenic and pro-angiogenic activities of endothelial colony forming cells in immunocompetent hosts.

Shafiee A, Patel J, Lee JS, Hutmacher DW, Fisk NM, Khosrotehrani K.

Sci Rep. 2017 Oct 19;7(1):13558. doi: 10.1038/s41598-017-13971-3.

43.

Fetal Bone Marrow-Derived Mesenchymal Stem/Stromal Cells Enhance Humanization and Bone Formation of BMP7 Loaded Scaffolds.

Shafiee A, Baldwin JG, Patel J, Holzapfel BM, Fisk NM, Khosrotehrani K, Hutmacher DW.

Biotechnol J. 2017 Dec;12(12). doi: 10.1002/biot.201700414. Epub 2017 Sep 25.

PMID:
28862380
44.

An Integrated Design, Material, and Fabrication Platform for Engineering Biomechanically and Biologically Functional Soft Tissues.

Bas O, D'Angella D, Baldwin JG, Castro NJ, Wunner FM, Saidy NT, Kollmannsberger S, Reali A, Rank E, De-Juan-Pardo EM, Hutmacher DW.

ACS Appl Mater Interfaces. 2017 Sep 6;9(35):29430-29437. doi: 10.1021/acsami.7b08617. Epub 2017 Aug 23.

PMID:
28816441
45.

Challenges and opportunities in the manufacture and expansion of cells for therapy.

Maartens JH, De-Juan-Pardo E, Wunner FM, Simula A, Voelcker NH, Barry SC, Hutmacher DW.

Expert Opin Biol Ther. 2017 Oct;17(10):1221-1233. doi: 10.1080/14712598.2017.1360273. Epub 2017 Aug 18. Review.

PMID:
28777667
46.

Scaffold curvature-mediated novel biomineralization process originates a continuous soft tissue-to-bone interface.

Paris M, Götz A, Hettrich I, Bidan CM, Dunlop JWC, Razi H, Zizak I, Hutmacher DW, Fratzl P, Duda GN, Wagermaier W, Cipitria A.

Acta Biomater. 2017 Sep 15;60:64-80. doi: 10.1016/j.actbio.2017.07.029. Epub 2017 Jul 20.

PMID:
28736221
47.

[Scaffold-based Bone Tissue Engineering].

Holzapfel BM, Rudert M, Hutmacher DW.

Orthopade. 2017 Aug;46(8):701-710. doi: 10.1007/s00132-017-3444-0. Review. German.

PMID:
28725934
48.

A humanised tissue-engineered bone model allows species-specific breast cancer-related bone metastasis in vivo.

Quent V, Taubenberger AV, Reichert JC, Martine LC, Clements JA, Hutmacher DW, Loessner D.

J Tissue Eng Regen Med. 2018 Feb;12(2):494-504. doi: 10.1002/term.2517. Epub 2017 Nov 29.

PMID:
28714574
49.

Lycopene reduces ovarian tumor growth and intraperitoneal metastatic load.

Holzapfel NP, Shokoohmand A, Wagner F, Landgraf M, Champ S, Holzapfel BM, Clements JA, Hutmacher DW, Loessner D.

Am J Cancer Res. 2017 Jun 1;7(6):1322-1336. eCollection 2017.

50.

3D printed lattices as an activation and expansion platform for T cell therapy.

Delalat B, Harding F, Gundsambuu B, De-Juan-Pardo EM, Wunner FM, Wille ML, Jasieniak M, Malatesta KAL, Griesser HJ, Simula A, Hutmacher DW, Voelcker NH, Barry SC.

Biomaterials. 2017 Sep;140:58-68. doi: 10.1016/j.biomaterials.2017.05.009. Epub 2017 Jun 7.

PMID:
28628776

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