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Items: 1 to 50 of 200

1.

Large uremic toxins: an unsolved problem in end-stage kidney disease.

Wolley MJ, Hutchison CA.

Nephrol Dial Transplant. 2018 Oct 1;33(suppl_3):iii6-iii11. doi: 10.1093/ndt/gfy179.

2.

Tuning Gene Activity by Inducible and Targeted Regulation of Gene Expression in Minimal Bacterial Cells.

Mariscal AM, Kakizawa S, Hsu JY, Tanaka K, González-González L, Broto A, Querol E, Lluch-Senar M, Piñero-Lambea C, Sun L, Weyman PD, Wise KS, Merryman C, Tse G, Moore AJ, Hutchison CA 3rd, Smith HO, Tomita M, Venter JC, Glass JI, Piñol J, Suzuki Y.

ACS Synth Biol. 2018 Jun 15;7(6):1538-1552. doi: 10.1021/acssynbio.8b00028. Epub 2018 May 22.

3.

Design and methods of the REMOVAL-HD study: a tRial Evaluating Mid cut-Off Value membrane clearance of Albumin and Light chains in HaemoDialysis patients.

Krishnasamy R, Hawley CM, Jardine MJ, Roberts MA, Cho YJ, Wong MG, Heath A, Nelson CL, Sen S, Mount PF, Pascoe EM, Darssan D, Vergara LA, Paul-Brent PA, Toussaint ND, Johnson DW, Hutchison CA.

BMC Nephrol. 2018 Apr 17;19(1):89. doi: 10.1186/s12882-018-0883-8.

4.

Exploring the Clinical Relevance of Providing Increased Removal of Large Middle Molecules.

Wolley M, Jardine M, Hutchison CA.

Clin J Am Soc Nephrol. 2018 May 7;13(5):805-814. doi: 10.2215/CJN.10110917. Epub 2018 Mar 5. Review.

PMID:
29507008
5.

Cognitive Behavioral Therapy (CBT) for Subacute Low Back Pain: a Systematic Review.

Mariano TY, Urman RD, Hutchison CA, Jamison RN, Edwards RR.

Curr Pain Headache Rep. 2018 Feb 23;22(3):15. doi: 10.1007/s11916-018-0669-5. Review.

PMID:
29476270
6.

The Association of Serum Free Light Chains With Mortality and Progression to End-Stage Renal Disease in Chronic Kidney Disease: Systematic Review and Individual Patient Data Meta-analysis.

Fraser SDS, Fenton A, Harris S, Shardlow A, Liabeuf S, Massy ZA, Burmeister A, Hutchison CA, Landray M, Emberson J, Kalra PA, Ritchie JP, Cockwell P, Taal MW.

Mayo Clin Proc. 2017 Nov;92(11):1671-1681. doi: 10.1016/j.mayocp.2017.08.021. Epub 2017 Nov 1. Review. Erratum in: Mayo Clin Proc. 2017 Dec;92 (12 ):1866. Kalra, Phil [corrected to Kalra, Phil A].

PMID:
29101935
7.

The Rationale for Expanded Hemodialysis Therapy (HDx).

Hutchison CA, Wolley M.

Contrib Nephrol. 2017;191:142-152. doi: 10.1159/000479262. Epub 2017 Sep 14. Review.

PMID:
28910797
8.

The treatment of paraprotein-related kidney disease.

Hutchison CA, Xiong F, Mollee P.

Curr Opin Nephrol Hypertens. 2017 Nov;26(6):477-483. doi: 10.1097/MNH.0000000000000369. Review.

PMID:
28885307
9.

Minimal Cells-Real and Imagined.

Glass JI, Merryman C, Wise KS, Hutchison CA 3rd, Smith HO.

Cold Spring Harb Perspect Biol. 2017 Dec 1;9(12). pii: a023861. doi: 10.1101/cshperspect.a023861. Review.

PMID:
28348033
10.

Laboratory testing in monoclonal gammopathy of renal significance (MGRS).

Leung N, Barnidge DR, Hutchison CA.

Clin Chem Lab Med. 2016 Jun 1;54(6):929-37. doi: 10.1515/cclm-2015-0994. Review.

11.

Design and synthesis of a minimal bacterial genome.

Hutchison CA 3rd, Chuang RY, Noskov VN, Assad-Garcia N, Deerinck TJ, Ellisman MH, Gill J, Kannan K, Karas BJ, Ma L, Pelletier JF, Qi ZQ, Richter RA, Strychalski EA, Sun L, Suzuki Y, Tsvetanova B, Wise KS, Smith HO, Glass JI, Merryman C, Gibson DG, Venter JC.

Science. 2016 Mar 25;351(6280):aad6253. doi: 10.1126/science.aad6253. Erratum in: ACS Chem Biol. 2016 May 20;11(5):1463.

PMID:
27013737
12.

Correction: The Association between Polyclonal Combined Serum Free Light Chain Concentration and Mortality in Individuals with Early Chronic Kidney Disease.

Assi LK, McIntyre N, Fraser S, Harris S, Hutchison CA, McIntyre CW, Cockwell P, Taal MW.

PLoS One. 2015 Oct 20;10(10):e0141404. doi: 10.1371/journal.pone.0141404. eCollection 2015. No abstract available.

13.

Patients with multiple myeloma have excellent long-term outcomes after recovery from dialysis-dependent acute kidney injury.

Yadav P, Hutchison CA, Basnayake K, Stringer S, Jesky M, Fifer L, Snell K, Pinney J, Drayson MT, Cook M, Cockwell P.

Eur J Haematol. 2016 Jun;96(6):610-7. doi: 10.1111/ejh.12644. Epub 2015 Sep 16.

PMID:
26248588
14.

The Association between Polyclonal Combined Serum Free Light Chain Concentration and Mortality in Individuals with Early Chronic Kidney Disease.

Assi LK, McIntyre N, Fraser S, Harris S, Hutchison CA, McIntyre CW, Cockwell P, Taal MW.

PLoS One. 2015 Jul 1;10(7):e0129980. doi: 10.1371/journal.pone.0129980. eCollection 2015. Erratum in: PLoS One. 2015;10(10):e0141404.

15.

Designer diatom episomes delivered by bacterial conjugation.

Karas BJ, Diner RE, Lefebvre SC, McQuaid J, Phillips AP, Noddings CM, Brunson JK, Valas RE, Deerinck TJ, Jablanovic J, Gillard JT, Beeri K, Ellisman MH, Glass JI, Hutchison CA 3rd, Smith HO, Venter JC, Allen AE, Dupont CL, Weyman PD.

Nat Commun. 2015 Apr 21;6:6925. doi: 10.1038/ncomms7925.

16.

Bacterial genome reduction using the progressive clustering of deletions via yeast sexual cycling.

Suzuki Y, Assad-Garcia N, Kostylev M, Noskov VN, Wise KS, Karas BJ, Stam J, Montague MG, Hanly TJ, Enriquez NJ, Ramon A, Goldgof GM, Richter RA, Vashee S, Chuang RY, Winzeler EA, Hutchison CA 3rd, Gibson DG, Smith HO, Glass JI, Venter JC.

Genome Res. 2015 Mar;25(3):435-44. doi: 10.1101/gr.182477.114. Epub 2015 Feb 5.

17.

Diagnosis of monoclonal gammopathy of renal significance.

Bridoux F, Leung N, Hutchison CA, Touchard G, Sethi S, Fermand JP, Picken MM, Herrera GA, Kastritis E, Merlini G, Roussel M, Fervenza FC, Dispenzieri A, Kyle RA, Nasr SH; International Kidney and Monoclonal Gammopathy Research Group.

Kidney Int. 2015 Apr;87(4):698-711. doi: 10.1038/ki.2014.408. Epub 2015 Jan 21. Review.

PMID:
25607108
18.

Rescue of mutant fitness defects using in vitro reconstituted designer transposons in Mycoplasma mycoides.

Karas BJ, Wise KS, Sun L, Venter JC, Glass JI, Hutchison CA 3rd, Smith HO, Suzuki Y.

Front Microbiol. 2014 Jul 23;5:369. doi: 10.3389/fmicb.2014.00369. eCollection 2014.

19.

Extended high cut-off haemodialysis for myeloma cast nephropathy in Auckland, 2008-2012.

Tan J, Lam-Po-Tang M, Hutchison CA, de Zoysa JR.

Nephrology (Carlton). 2014 Jul;19(7):432-5. doi: 10.1111/nep.12267.

PMID:
24931113
20.

Value of antibodies to free light chains in immunoperoxidase studies of renal biopsies.

Owen-Casey MP, Sim R, Cook HT, Roufosse CA, Gillmore JD, Gilbertson JA, Hutchison CA, Howie AJ.

J Clin Pathol. 2014 Aug;67(8):661-6. doi: 10.1136/jclinpath-2014-202231. Epub 2014 May 9.

21.

The impact of exercise on the variation of serum free light chains.

Jacobs JF, Eijsvogels TM, van der Geest KS, Koenen HJ, Hutchison CA, Boots AM, Hopman MT, Joosten I.

Clin Chem Lab Med. 2014 Nov;52(11):e239-42. doi: 10.1515/cclm-2014-0352. No abstract available.

PMID:
24803612
22.

Serum polyclonal immunoglobulin free light chain levels predict mortality in people with chronic kidney disease.

Hutchison CA, Burmeister A, Harding SJ, Basnayake K, Church H, Jesky MD, White K, Green CE, Stringer SJ, Bassett P, Ferro CJ, Cockwell P.

Mayo Clin Proc. 2014 May;89(5):615-22. doi: 10.1016/j.mayocp.2014.01.028.

23.

Elevated serum free light chains predict cardiovascular events in type 2 diabetes.

Bellary S, Faint JM, Assi LK, Hutchison CA, Harding SJ, Raymond NT, Barnett AH.

Diabetes Care. 2014 Jul;37(7):2028-30. doi: 10.2337/dc13-2227. Epub 2014 Apr 17.

PMID:
24742658
24.

Transferring whole genomes from bacteria to yeast spheroplasts using entire bacterial cells to reduce DNA shearing.

Karas BJ, Jablanovic J, Irvine E, Sun L, Ma L, Weyman PD, Gibson DG, Glass JI, Venter JC, Hutchison CA 3rd, Smith HO, Suzuki Y.

Nat Protoc. 2014 Apr;9(4):743-50. doi: 10.1038/nprot.2014.045. Epub 2014 Mar 6.

PMID:
24603933
25.

Assembly of eukaryotic algal chromosomes in yeast.

Karas BJ, Molparia B, Jablanovic J, Hermann WJ, Lin YC, Dupont CL, Tagwerker C, Yonemoto IT, Noskov VN, Chuang RY, Allen AE, Glass JI, Hutchison CA 3rd, Smith HO, Venter JC, Weyman PD.

J Biol Eng. 2013 Dec 10;7(1):30. doi: 10.1186/1754-1611-7-30.

26.

The relationship between high-sensitivity CRP and polyclonal free light chains as markers of inflammation in chronic disease.

Burmeister A, Assi LK, Ferro CJ, Hughes RG, Barnett AH, Bellary S, Cockwell P, Pratt G, Hutchison CA.

Int J Lab Hematol. 2014 Aug;36(4):415-24. doi: 10.1111/ijlh.12159. Epub 2013 Nov 5.

PMID:
24188493
27.

Kinetic modelling of haemodialysis removal of myoglobin in rhabdomyolysis patients.

Keir R, Evans ND, Hutchison CA, Vigano MR, Stella A, Fabbrini P, Storr M, Chappell MJ.

Comput Methods Programs Biomed. 2014 May;114(3):e29-38. doi: 10.1016/j.cmpb.2013.07.017. Epub 2013 Aug 14.

PMID:
24008249
28.

Assembly of large, high G+C bacterial DNA fragments in yeast.

Noskov VN, Karas BJ, Young L, Chuang RY, Gibson DG, Lin YC, Stam J, Yonemoto IT, Suzuki Y, Andrews-Pfannkoch C, Glass JI, Smith HO, Hutchison CA 3rd, Venter JC, Weyman PD.

ACS Synth Biol. 2012 Jul 20;1(7):267-73. doi: 10.1021/sb3000194. Epub 2012 May 21.

PMID:
23651249
29.

Direct transfer of whole genomes from bacteria to yeast.

Karas BJ, Jablanovic J, Sun L, Ma L, Goldgof GM, Stam J, Ramon A, Manary MJ, Winzeler EA, Venter JC, Weyman PD, Gibson DG, Glass JI, Hutchison CA 3rd, Smith HO, Suzuki Y.

Nat Methods. 2013 May;10(5):410-2. doi: 10.1038/nmeth.2433. Epub 2013 Mar 31.

30.

Monoclonal gammopathy of renal significance: when MGUS is no longer undetermined or insignificant.

Leung N, Bridoux F, Hutchison CA, Nasr SH, Cockwell P, Fermand JP, Dispenzieri A, Song KW, Kyle RA; International Kidney and Monoclonal Gammopathy Research Group.

Blood. 2012 Nov 22;120(22):4292-5. doi: 10.1182/blood-2012-07-445304. Epub 2012 Oct 9. Review.

31.

Sequence analysis of a complete 1.66 Mb Prochlorococcus marinus MED4 genome cloned in yeast.

Tagwerker C, Dupont CL, Karas BJ, Ma L, Chuang RY, Benders GA, Ramon A, Novotny M, Montague MG, Venepally P, Brami D, Schwartz A, Andrews-Pfannkoch C, Gibson DG, Glass JI, Smith HO, Venter JC, Hutchison CA 3rd.

Nucleic Acids Res. 2012 Nov 1;40(20):10375-83. doi: 10.1093/nar/gks823. Epub 2012 Aug 31.

32.

Monoclonal gammopathy of undetermined significance: an update for nephrologists.

Parry HM, Pratt G, Hutchison CA.

Adv Chronic Kidney Dis. 2012 Sep;19(5):291-6. doi: 10.1053/j.ackd.2012.07.006. Review.

PMID:
22920639
33.

Diagnostic accuracy of monoclonal antibody based serum immunoglobulin free light chain immunoassays in myeloma cast nephropathy.

Hutchison CA, Cockwell P, Cook M.

BMC Clin Pathol. 2012 Aug 9;12:12. doi: 10.1186/1472-6890-12-12.

34.

Novel approaches for reducing free light chains in patients with myeloma kidney.

Hutchison CA, Bladé J, Cockwell P, Cook M, Drayson M, Fermand JP, Kastritis E, Kyle R, Leung N, Pasquali S, Winearls C; International Kidney and Monoclonal Gammopathy Research Group.

Nat Rev Nephrol. 2012 Feb 21;8(4):234-43. doi: 10.1038/nrneph.2012.14. Review.

PMID:
22349488
35.

Immunoglobulin free light chain levels and recovery from myeloma kidney on treatment with chemotherapy and high cut-off haemodialysis.

Hutchison CA, Heyne N, Airia P, Schindler R, Zickler D, Cook M, Cockwell P, Grima D.

Nephrol Dial Transplant. 2012 Oct;27(10):3823-8. doi: 10.1093/ndt/gfr773. Epub 2012 Jan 23.

PMID:
22273664
36.

Cloning the Acholeplasma laidlawii PG-8A genome in Saccharomyces cerevisiae as a yeast centromeric plasmid.

Karas BJ, Tagwerker C, Yonemoto IT, Hutchison CA 3rd, Smith HO.

ACS Synth Biol. 2012 Jan 20;1(1):22-8. doi: 10.1021/sb200013j. Epub 2012 Jan 10.

PMID:
23651007
37.

Early survival and duration of hospital admission in rhabdomyolysis: ICNARC Case Mix Programme Database.

Hutchison CA, Patel K, Whitehouse T.

Crit Care. 2011;15(6):452. doi: 10.1186/cc10492. Epub 2011 Nov 16. No abstract available.

38.

The pathogenesis and diagnosis of acute kidney injury in multiple myeloma.

Hutchison CA, Batuman V, Behrens J, Bridoux F, Sirac C, Dispenzieri A, Herrera GA, Lachmann H, Sanders PW; International Kidney and Monoclonal Gammopathy Research Group.

Nat Rev Nephrol. 2011 Nov 1;8(1):43-51. doi: 10.1038/nrneph.2011.168. Review.

39.

Serum free light chains and the risk of ESRD and death in CKD.

Haynes R, Hutchison CA, Emberson J, Dasgupta T, Wheeler DC, Townend JN, Landray MJ, Cockwell P.

Clin J Am Soc Nephrol. 2011 Dec;6(12):2829-37. doi: 10.2215/CJN.03350411. Epub 2011 Oct 27.

40.

Polyclonal immunoglobulin free light chains as a potential biomarker of immune stimulation and inflammation.

Hutchison CA, Landgren O.

Clin Chem. 2011 Oct;57(10):1387-9. doi: 10.1373/clinchem.2011.169433. No abstract available.

41.

High cut-off dialysis membranes: current uses and future potential.

Gondouin B, Hutchison CA.

Adv Chronic Kidney Dis. 2011 May;18(3):180-7. doi: 10.1053/j.ackd.2011.02.006. Review.

PMID:
21531324
42.

Early reduction of serum-free light chains associates with renal recovery in myeloma kidney.

Hutchison CA, Cockwell P, Stringer S, Bradwell A, Cook M, Gertz MA, Dispenzieri A, Winters JL, Kumar S, Rajkumar SV, Kyle RA, Leung N.

J Am Soc Nephrol. 2011 Jun;22(6):1129-36. doi: 10.1681/ASN.2010080857. Epub 2011 Apr 21.

43.

The biology of immunoglobulin free light chains and kidney injury.

Basnayake K, Stringer SJ, Hutchison CA, Cockwell P.

Kidney Int. 2011 Jun;79(12):1289-301. doi: 10.1038/ki.2011.94. Epub 2011 Apr 13. Review.

44.

Aggregated serum free light chains may prevent adequate removal by high cut-off haemodialysis.

Harding S, Provot F, Beuscart JB, Cook M, Bradwell AR, Stringer S, White D, Cockwell P, Hutchison CA.

Nephrol Dial Transplant. 2011 Apr;26(4):1438. doi: 10.1093/ndt/gfr019. Epub 2011 Mar 15.

PMID:
21406545
45.

Renal impairment in multiple myeloma: time is of the essence.

Hutchison CA, Bridoux F.

J Clin Oncol. 2011 Apr 10;29(11):e312-3; author reply e314. doi: 10.1200/JCO.2010.34.3038. Epub 2011 Feb 22. No abstract available.

PMID:
21343553
46.

Modelled cost-effectiveness of high cut-off haemodialysis compared to standard haemodialysis in the management of myeloma kidney.

Grima DT, Airia P, Attard C, Hutchison CA.

Curr Med Res Opin. 2011 Feb;27(2):383-91. doi: 10.1185/03007995.2010.543125. Epub 2010 Dec 23.

PMID:
21175375
47.

Chemical synthesis of the mouse mitochondrial genome.

Gibson DG, Smith HO, Hutchison CA 3rd, Venter JC, Merryman C.

Nat Methods. 2010 Nov;7(11):901-3. doi: 10.1038/nmeth.1515. Epub 2010 Oct 10.

PMID:
20935651
48.

Free light-chains and renal disorders: when small is worse.

Hutchison CA, Pratt G.

Lancet. 2010 Oct 9;376(9748):1220; author reply 1221-2. doi: 10.1016/S0140-6736(10)61873-9. No abstract available.

PMID:
20934588
49.

Differential progression of renal scarring and determinants of late renal recovery in sustained dialysis dependent acute kidney injury secondary to myeloma kidney.

Basnayake K, Cheung CK, Sheaff M, Fuggle W, Kamel D, Nakoinz S, Hutchison CA, Cook M, Stoves J, Bradwell AR, Cockwell P.

J Clin Pathol. 2010 Oct;63(10):884-7. doi: 10.1136/jcp.2010.079236.

PMID:
20876319
50.

Management options for cast nephropathy in multiple myeloma.

Cockwell P, Hutchison CA.

Curr Opin Nephrol Hypertens. 2010 Nov;19(6):550-5. doi: 10.1097/MNH.0b013e32833ef72c. Review.

PMID:
20827195

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