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Statistical analysis plan for the Dex-CSDH trial: a randomised, double-blind, placebo-controlled trial of a 2-week course of dexamethasone for adult patients with a symptomatic chronic subdural haematoma.

Allison A, Edlmann E, Kolias AG, Davis-Wilkie C, Mee H, Thelin EP, Turner C, Hutchinson PJ, Bond S.

Trials. 2019 Dec 10;20(1):698. doi: 10.1186/s13063-019-3866-6.


Aptamer-modified gold nanoparticles for rapid aggregation-based detection of inflammation: an optical assay for interleukin-6.

Giorgi-Coll S, Marín MJ, Sule O, Hutchinson PJ, Carpenter KLH.

Mikrochim Acta. 2019 Dec 4;187(1):13. doi: 10.1007/s00604-019-3975-7.


WSES consensus conference guidelines: monitoring and management of severe adult traumatic brain injury patients with polytrauma in the first 24 hours.

Picetti E, Rossi S, Abu-Zidan FM, Ansaloni L, Armonda R, Baiocchi GL, Bala M, Balogh ZJ, Berardino M, Biffl WL, Bouzat P, Buki A, Ceresoli M, Chesnut RM, Chiara O, Citerio G, Coccolini F, Coimbra R, Di Saverio S, Fraga GP, Gupta D, Helbok R, Hutchinson PJ, Kirkpatrick AW, Kinoshita T, Kluger Y, Leppaniemi A, Maas AIR, Maier RV, Minardi F, Moore EE, Myburgh JA, Okonkwo DO, Otomo Y, Rizoli S, Rubiano AM, Sahuquillo J, Sartelli M, Scalea TM, Servadei F, Stahel PF, Stocchetti N, Taccone FS, Tonetti T, Velmahos G, Weber D, Catena F.

World J Emerg Surg. 2019 Nov 29;14:53. doi: 10.1186/s13017-019-0270-1. eCollection 2019. Review.


Relationship Between Measures of Cerebrovascular Reactivity and Intracranial Lesion Progression in Acute TBI Patients: an Exploratory Analysis.

Mathieu F, Zeiler FA, Whitehouse DP, Das T, Ercole A, Smielewski P, Hutchinson PJ, Czosnyka M, Newcombe VFJ, Menon DK.

Neurocrit Care. 2019 Dec 3. doi: 10.1007/s12028-019-00885-3. [Epub ahead of print]


Implementation of duty of candour within neurosurgery: a national survey and framework for improved application in clinical practice.

Basu S, Marcus HJ, Sayal P, Kitchen N, Ley R, Hutchinson PJ, Thorne L.

Ann R Coll Surg Engl. 2019 Nov 22:1-5. doi: 10.1308/rcsann.2019.0124. [Epub ahead of print]


Single procedure revision cranioplasty with intra-operative autoclave following titanium plate exposure.

Moneim J, Wenlock RD, Wells AJ, Price RD, Timofeev I, Helmy A, Hutchinson PJ.

Br J Neurosurg. 2019 Nov 18:1-4. doi: 10.1080/02688697.2019.1690129. [Epub ahead of print]


Mapping global evidence on strategies and interventions in neurotrauma and road traffic collisions prevention: a scoping review protocol.

M Selveindran S, Khan MM, Simadibrata DM, Hutchinson PJA, Brayne C, Hill C, Kolias A, Joannides AJ, Servadei F, Rubiano AM, Shabani HK.

BMJ Open. 2019 Nov 12;9(11):e031517. doi: 10.1136/bmjopen-2019-031517.


Hinge/floating craniotomy as an alternative technique for cerebral decompression: a scoping review.

Layard Horsfall H, Mohan M, Devi BI, Adeleye AO, Shukla DP, Bhat D, Khan M, Clark DJ, Chari A, Servadei F, Khan T, Rubiano AM, Hutchinson PJ, Kolias AG.

Neurosurg Rev. 2019 Nov 11. doi: 10.1007/s10143-019-01180-7. [Epub ahead of print] Review.


Spatial and Temporal Pattern of Ischemia and Abnormal Vascular Function Following Traumatic Brain Injury.

Launey Y, Fryer TD, Hong YT, Steiner LA, Nortje J, Veenith TV, Hutchinson PJ, Ercole A, Gupta AK, Aigbirhio FI, Pickard JD, Coles JP, Menon DK.

JAMA Neurol. 2019 Nov 11. doi: 10.1001/jamaneurol.2019.3854. [Epub ahead of print]


A comparison of publication to TBI burden ratio of low- and middle-income countries versus high-income countries: how can we improve worldwide care of TBI?

Tropeano MP, Spaggiari R, Ileyassoff H, Park KB, Kolias AG, Hutchinson PJ, Servadei F.

Neurosurg Focus. 2019 Nov 1;47(5):E5. doi: 10.3171/2019.8.FOCUS19507.


Emergency neurosurgery for traumatic brain injury: the need for a national and international registry study.

Solla DJF, Quadros DG, Kolias AG, Clark DJ, Hutchinson PJ, Teixeira MJ, Andrade AF, Paiva WS.

Rev Assoc Med Bras (1992). 2019 Sep 12;65(8):1035-1036. doi: 10.1590/1806-9282.65.8.1035. No abstract available.


Case-mix, care pathways, and outcomes in patients with traumatic brain injury in CENTER-TBI: a European prospective, multicentre, longitudinal, cohort study.

Steyerberg EW, Wiegers E, Sewalt C, Buki A, Citerio G, De Keyser V, Ercole A, Kunzmann K, Lanyon L, Lecky F, Lingsma H, Manley G, Nelson D, Peul W, Stocchetti N, von Steinbüchel N, Vande Vyvere T, Verheyden J, Wilson L, Maas AIR, Menon DK; CENTER-TBI Participants and Investigators.

Lancet Neurol. 2019 Oct;18(10):923-934. doi: 10.1016/S1474-4422(19)30232-7.


Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multicentre, single-blinded, randomised trial and economic evaluation.

Mallucci CL, Jenkinson MD, Conroy EJ, Hartley JC, Brown M, Dalton J, Kearns T, Moitt T, Griffiths MJ, Culeddu G, Solomon T, Hughes D, Gamble C; BASICS Study collaborators.

Lancet. 2019 Oct 26;394(10208):1530-1539. doi: 10.1016/S0140-6736(19)31603-4. Epub 2019 Sep 12. Erratum in: Lancet. 2019 Sep 18;:.


The Evolution of the Role of External Ventricular Drainage in Traumatic Brain Injury.

Chau CYC, Craven CL, Rubiano AM, Adams H, Tülü S, Czosnyka M, Servadei F, Ercole A, Hutchinson PJ, Kolias AG.

J Clin Med. 2019 Sep 10;8(9). pii: E1422. doi: 10.3390/jcm8091422. Review.


Correction: Modelling outcomes after paediatric brain injury with admission laboratory values: a machine-learning approach.

Kayhanian S, Young AMH, Mangla C, Jalloh I, Fernandes HM, Garnett MR, Hutchinson PJ, Agrawal S.

Pediatr Res. 2019 Nov;86(5):675. doi: 10.1038/s41390-019-0545-y.


Delineating Astrocytic Cytokine Responses in a Human Stem Cell Model of Neural Trauma.

Thelin EP, Hall CE, Tyzack GE, Frostell A, Giorgi-Coll S, Alam A, Carpenter KLH, Mitchell J, Tajsic T, Hutchinson PJ, Patani R, Helmy A.

J Neurotrauma. 2019 Sep 18. doi: 10.1089/neu.2019.6480. [Epub ahead of print]


Surgery for intracerebral haemorrhage.

Kolias AG, Marcus HJ, Broekman ML, Hutchinson PJ, McCulloch P.

Lancet. 2019 Aug 24;394(10199):e21. doi: 10.1016/S0140-6736(19)31410-2. No abstract available.


Academic neurosurgery in the UK: present and future directions.

Waqar M, Davies BM, Zakaria R, Barone DG, Kolias AG, Yu KK, Ellenbogen JR, Brennan PM, Kotter MR, Gray WP, King AT, Turner C, Kitchen N, May P, Jenkinson MD, Hutchinson PJ.

Postgrad Med J. 2019 Oct;95(1128):524-530. doi: 10.1136/postgradmedj-2019-136805. Epub 2019 Aug 20.


Modelling outcomes after paediatric brain injury with admission laboratory values: a machine-learning approach.

Kayhanian S, Young AMH, Mangla C, Jalloh I, Fernandes HM, Garnett MR, Hutchinson PJ, Agrawal S.

Pediatr Res. 2019 Nov;86(5):641-645. doi: 10.1038/s41390-019-0510-9. Epub 2019 Jul 26. Erratum in: Pediatr Res. 2019 Aug 28;:.


A comparison of radiological descriptions of spinal cord compression with quantitative measures, and their role in non-specialist clinical management.

Tempest-Mitchell J, Hilton B, Davies BM, Nouri A, Hutchinson PJ, Scoffings DJ, Mannion RJ, Trivedi R, Timofeev I, Crawford JR, Hay D, Laing RJ, Kotter MRN.

PLoS One. 2019 Jul 22;14(7):e0219380. doi: 10.1371/journal.pone.0219380. eCollection 2019.


Dextran 500 Improves Recovery of Inflammatory Markers: An In Vitro Microdialysis Study.

Giorgi-Coll S, Thelin EP, Lindblad C, Tajsic T, Carpenter KLH, Hutchinson PJA, Helmy A.

J Neurotrauma. 2019 Aug 6. doi: 10.1089/neu.2019.6513. [Epub ahead of print]


Footprint of Reports From Low- and Low- to Middle-Income Countries in the Neurosurgical Data: A Study From 2015 to 2017.

Servadei F, Tropeano MP, Spaggiari R, Cannizzaro D, Al Fauzi A, Bajamal AH, Khan T, Kolias AG, Hutchinson PJ.

World Neurosurg. 2019 Oct;130:e822-e830. doi: 10.1016/j.wneu.2019.06.230. Epub 2019 Jul 9.


Consensus statement from the International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury : Consensus statement.

Hutchinson PJ, Kolias AG, Tajsic T, Adeleye A, Aklilu AT, Apriawan T, Bajamal AH, Barthélemy EJ, Devi BI, Bhat D, Bulters D, Chesnut R, Citerio G, Cooper DJ, Czosnyka M, Edem I, El-Ghandour NMF, Figaji A, Fountas KN, Gallagher C, Hawryluk GWJ, Iaccarino C, Joseph M, Khan T, Laeke T, Levchenko O, Liu B, Liu W, Maas A, Manley GT, Manson P, Mazzeo AT, Menon DK, Michael DB, Muehlschlegel S, Okonkwo DO, Park KB, Rosenfeld JV, Rosseau G, Rubiano AM, Shabani HK, Stocchetti N, Timmons SD, Timofeev I, Uff C, Ullman JS, Valadka A, Waran V, Wells A, Wilson MH, Servadei F.

Acta Neurochir (Wien). 2019 Jul;161(7):1261-1274. doi: 10.1007/s00701-019-03936-y. Epub 2019 May 28. Review.


The History of Decompressive Craniectomy in Traumatic Brain Injury.

Rossini Z, Nicolosi F, Kolias AG, Hutchinson PJ, De Sanctis P, Servadei F.

Front Neurol. 2019 May 8;10:458. doi: 10.3389/fneur.2019.00458. eCollection 2019. Review.


A systems approach to trauma care in Myanmar: from health partnership to academic collaboration.

Bashford T, Myint PPN, Win S, Thu M, Naing MM, Burnstein R, Hlaing TT, Brealey E, Hutchinson PJ, Clarkson J.

Future Healthc J. 2018 Oct;5(3):171-175. doi: 10.7861/futurehosp.5-3-171.


Dex-CSDH randomised, placebo-controlled trial of dexamethasone for chronic subdural haematoma: report of the internal pilot phase.

Edlmann E, Thelin EP, Caldwell K, Turner C, Whitfield P, Bulters D, Holton P, Suttner N, Owusu-Agyemang K, Al-Tamimi YZ, Gatt D, Thomson S, Anderson IA, Richards O, Gherle M, Toman E, Nandi D, Kane P, Pantaleo B, Davis-Wilkie C, Tarantino S, Barton G, Marcus HJ, Chari A, Belli A, Bond S, Gafoor R, Dawson S, Whitehead L, Brennan P, Wilkinson I, Kolias AG, Hutchinson PJA; Dex-CSDH trial collaborative and BNTRC collaborative.

Sci Rep. 2019 Apr 10;9(1):5885. doi: 10.1038/s41598-019-42087-z.


Correction to: Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial.

Kolias AG, Edlmann E, Thelin EP, Bulters D, Holton P, Suttner N, Owusu-Agyemang K, Al-Tamimi YZ, Gatt D, Thomson S, Anderson IA, Richards O, Whitfield P, Gherle M, Caldwell K, Davis-Wilkie C, Tarantino S, Barton G, Marcus HJ, Chari A, Brennan P, Belli A, Bond S, Turner C, Whitehead L, Wilkinson I, Hutchinson PJ; British Neurosurgical Trainee Research Collaborative (BNTRC) and Dex-CSDH Trial Collaborators.

Trials. 2019 Mar 18;20(1):175. doi: 10.1186/s13063-019-3283-x.


Metabolism and inflammation: implications for traumatic brain injury therapeutics.

Killen MJ, Giorgi-Coll S, Helmy A, Hutchinson PJ, Carpenter KL.

Expert Rev Neurother. 2019 Mar;19(3):227-242. doi: 10.1080/14737175.2019.1582332. Epub 2019 Mar 8.


Thresholds for identifying pathological intracranial pressure in paediatric traumatic brain injury.

Kayhanian S, Young AMH, Ewen RL, Piper RJ, Guilfoyle MR, Donnelly J, Fernandes HM, Garnett M, Smielewski P, Czosnyka M, Agrawal S, Hutchinson PJ.

Sci Rep. 2019 Mar 5;9(1):3537. doi: 10.1038/s41598-019-39848-1.


Primum non nocere: a call for balance when reporting on CTE.

Stewart W, Allinson K, Al-Sarraj S, Bachmeier C, Barlow K, Belli A, Burns MP, Carson A, Crawford F, Dams-O'Connor K, Diaz-Arrastia R, Dixon CE, Edlow BL, Ferguson S, Fischl B, Folkerth RD, Gentleman S, Giza CC, Grady MS, Helmy A, Herceg M, Holton JL, Howell D, Hutchinson PJ, Iacono D, Iglesias JE, Ikonomovic MD, Johnson VE, Keene CD, Kofler JK, Koliatsos VE, Lee EB, Levin H, Lifshitz J, Ling H, Loane DJ, Love S, Maas AI, Marklund N, Master CL, McElvenny DM, Meaney DF, Menon DK, Montine TJ, Mouzon B, Mufson EJ, Ojo JO, Prins M, Revesz T, Ritchie CW, Smith C, Sylvester R, Tang CY, Trojanowski JQ, Urankar K, Vink R, Wellington C, Wilde EA, Wilson L, Yeates K, Smith DH.

Lancet Neurol. 2019 Mar;18(3):231-233. doi: 10.1016/S1474-4422(19)30020-1. Epub 2019 Feb 12. No abstract available. Erratum in: Lancet Neurol. 2019 Apr;18(4):e3.


Correlation of Blood Biomarkers and Biomarker Panels with Traumatic Findings on Computed Tomography after Traumatic Brain Injury.

Posti JP, Takala RSK, Lagerstedt L, Dickens AM, Hossain I, Mohammadian M, Ala-Seppälä H, Frantzén J, van Gils M, Hutchinson PJ, Katila AJ, Maanpää HR, Menon DK, Newcombe VF, Tallus J, Hrusovsky K, Wilson DH, Gill J, Sanchez JC, Tenovuo O, Zetterberg H, Blennow K.

J Neurotrauma. 2019 Jul 15;36(14):2178-2189. doi: 10.1089/neu.2018.6254. Epub 2019 Apr 5.


A case series of early and late cranioplasty-comparison of surgical outcomes.

Bjornson A, Tajsic T, Kolias AG, Wells A, Naushahi MJ, Anwar F, Helmy A, Timofeev I, Hutchinson PJ.

Acta Neurochir (Wien). 2019 Mar;161(3):467-472. doi: 10.1007/s00701-019-03820-9. Epub 2019 Feb 4.


Correction to: Variation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study.

van Essen TA, den Boogert HF, Cnossen MC, de Ruiter GCW, Haitsma I, Polinder S, Steyerberg EW, Menon D, Maas AIR, Lingsma HF, Peul WC; CENTER-TBI Investigators and Participants.

Acta Neurochir (Wien). 2019 Mar;161(3):451-455. doi: 10.1007/s00701-019-03815-6.


Glucose Dynamics of Cortical Spreading Depolarization in Acute Brain Injury: A Systematic Review.

Stevens AR, Ng IHX, Helmy A, Hutchinson PJA, Menon DK, Ercole A.

J Neurotrauma. 2019 Jul 15;36(14):2153-2166. doi: 10.1089/neu.2018.6175. Epub 2019 Mar 28.


Traumatic brain injury: global collaboration for a global challenge.

Kolias AG, Rubiano AM, Figaji A, Servadei F, Hutchinson PJ.

Lancet Neurol. 2019 Feb;18(2):136-137. doi: 10.1016/S1474-4422(18)30494-0. No abstract available.


Genetic drivers of cerebral blood flow dysfunction in TBI: a speculative synthesis.

Zeiler FA, Thelin EP, Donnelly J, Stevens AR, Smielewski P, Czosnyka M, Hutchinson PJ, Menon DK.

Nat Rev Neurol. 2019 Jan;15(1):25-39. doi: 10.1038/s41582-018-0105-9. Review.


Social media for dissemination and public engagement in neurosurgery-the example of Brainbook.

Alamri A, Rogers P, Kearns C, Doke T, Al-Habib A, Servadei F, Hutchinson PJ, Kolias AG, Uff C.

Acta Neurochir (Wien). 2019 Jan;161(1):5-9. doi: 10.1007/s00701-018-3757-8. Epub 2018 Dec 10.


Influence of Antiplatelet and Anticoagulant Drug Use on Outcomes after Chronic Subdural Hematoma Drainage.

Poon MTC, Rea C, Kolias AG, Brennan PM; British Neurosurgical Trainee Research Collaborative (BNTRC).

J Neurotrauma. 2019 Jan 30. doi: 10.1089/neu.2018.6080. [Epub ahead of print]


Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial.

Kolias AG, Edlmann E, Thelin EP, Bulters D, Holton P, Suttner N, Owusu-Agyemang K, Al-Tamimi YZ, Gatt D, Thomson S, Anderson IA, Richards O, Whitfield P, Gherle M, Caldwell K, Davis-Wilkie C, Tarantino S, Barton G, Marcus HJ, Chari A, Brennan P, Belli A, Bond S, Turner C, Whitehead L, Wilkinson I, Hutchinson PJ; British Neurosurgical Trainee Research Collaborative (BNTRC) and Dex-CSDH Trial Collaborators.

Trials. 2018 Dec 4;19(1):670. doi: 10.1186/s13063-018-3050-4. Erratum in: Trials. 2019 Mar 18;20(1):175. Zolnouria, Ardalan [corrected to Zolnourian, Ardalan].


A neurosurgical approach to traumatic brain injury and post-traumatic hypopituitarism.

Tan CL, Hutchinson PJ.

Pituitary. 2019 Jun;22(3):332-337. doi: 10.1007/s11102-018-0925-z. Review.


Twenty-Five Years of Intracranial Pressure Monitoring After Severe Traumatic Brain Injury: A Retrospective, Single-Center Analysis.

Donnelly J, Czosnyka M, Adams H, Cardim D, Kolias AG, Zeiler FA, Lavinio A, Aries M, Robba C, Smielewski P, Hutchinson PJA, Menon DK, Pickard JD, Budohoski KP.

Neurosurgery. 2019 Jul 1;85(1):E75-E82. doi: 10.1093/neuros/nyy468.


The current status of decompressive craniectomy in traumatic brain injury.

Kolias AG, Viaroli E, Rubiano AM, Adams H, Khan T, Gupta D, Adeleye A, Iaccarino C, Servadei F, Devi BI, Hutchinson PJ.

Curr Trauma Rep. 2018 Sep 1;4(4):326-332. doi: 10.1007/s40719-018-0147-x.


Brain death and postmortem organ donation: report of a questionnaire from the CENTER-TBI study.

van Veen E, van der Jagt M, Cnossen MC, Maas AIR, de Beaufort ID, Menon DK, Citerio G, Stocchetti N, Rietdijk WJR, van Dijck JTJM, Kompanje EJO; CENTER-TBI investigators and participants.

Crit Care. 2018 Nov 16;22(1):306. doi: 10.1186/s13054-018-2241-4.


Pharmacological management of post-traumatic seizures in adults: current practice patterns in the UK and the Republic of Ireland.

Mee H, Kolias AG, Chari A, Ercole A, Lecky F, Turner C, Tudur-Smith C, Coles J, Anwar F, Belli A, Manford M, Ham T, McMahon C, Bulters D, Uff C, Duncan JS, Wilson MH, Marson AG, Hutchinson PJ.

Acta Neurochir (Wien). 2019 Mar;161(3):457-464. doi: 10.1007/s00701-018-3683-9. Epub 2018 Oct 1.


Central versus Local Radiological Reading of Acute Computed Tomography Characteristics in Multi-Center Traumatic Brain Injury Research.

Vande Vyvere T, Wilms G, Claes L, Martin Leon F, Nieboer D, Verheyden J, van den Hauwe L, Pullens P, Maas AIR, Parizel PM; Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Investigators and Participants.

J Neurotrauma. 2019 Apr 1;36(7):1080-1092. doi: 10.1089/neu.2018.6061. Epub 2018 Dec 11.


Phosphorus spectroscopy in acute TBI demonstrates metabolic changes that relate to outcome in the presence of normal structural MRI.

Stovell MG, Mada MO, Carpenter TA, Yan JL, Guilfoyle MR, Jalloh I, Welsh KE, Helmy A, Howe DJ, Grice P, Mason A, Giorgi-Coll S, Gallagher CN, Murphy MP, Menon DK, Hutchinson PJ, Carpenter KL.

J Cereb Blood Flow Metab. 2018 Sep 18:271678X18799176. doi: 10.1177/0271678X18799176. [Epub ahead of print]


Longitudinal Bedside Assessments of Brain Networks in Disorders of Consciousness: Case Reports From the Field.

Bareham CA, Allanson J, Roberts N, Hutchinson PJA, Pickard JD, Menon DK, Chennu S.

Front Neurol. 2018 Aug 21;9:676. doi: 10.3389/fneur.2018.00676. eCollection 2018.


Does Drain Position and Duration Influence Outcomes in Patients Undergoing Burr-Hole Evacuation of Chronic Subdural Hematoma? Lessons from a UK Multicenter Prospective Cohort Study.

Glancz LJ, Poon MTC, Coulter IC, Hutchinson PJ, Kolias AG, Brennan PM; British Neurosurgical Trainee Research Collaborative (BNTRC).

Neurosurgery. 2019 Oct 1;85(4):486-493. doi: 10.1093/neuros/nyy366.


Concussion in Motorsport? Experience, Knowledge, Attitudes, and Priorities of Medical Personnel and Drivers.

Adams SA, Turner AP, Richards H, Hutchinson PJ.

Clin J Sport Med. 2018 Aug 13. doi: 10.1097/JSM.0000000000000647. [Epub ahead of print]


The effect of succinate on brain NADH/NAD+ redox state and high energy phosphate metabolism in acute traumatic brain injury.

Stovell MG, Mada MO, Helmy A, Carpenter TA, Thelin EP, Yan JL, Guilfoyle MR, Jalloh I, Howe DJ, Grice P, Mason A, Giorgi-Coll S, Gallagher CN, Murphy MP, Menon DK, Hutchinson PJ, Carpenter KLH.

Sci Rep. 2018 Jul 24;8(1):11140. doi: 10.1038/s41598-018-29255-3.

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